CRCGN017_MCF10A.WT.HP_24H:J13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

44 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:J13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.9072
SNAP25 synaptosomal-associated protein, 25kDa 4.48467
MAP7 microtubule-associated protein 7 4.4689
SSBP2 single-stranded DNA binding protein 2 4.26627
FGFR4 fibroblast growth factor receptor 4 3.87628
ATMIN ATM interactor 3.23432
AHCYL1 adenosylhomocysteinase-like 1 2.35803
CCNF cyclin F 2.26207
GCSH glycine cleavage system protein H (aminomethyl carrier) 2.13535
TOB2 transducer of ERBB2, 2 2.1193
HLA-DRA major histocompatibility complex, class II, DR alpha 2.11217
HBB hemoglobin, beta 2.08198
PISD phosphatidylserine decarboxylase 2.0681
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 2.0584

decreased expression

Symbol Name Standardized Value
GOLT1B golgi transport 1B -5.3026
S100A8 S100 calcium binding protein A8 -5.0
VAT1 vesicle amine transport 1 -4.44795
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -4.39022
DNM1L dynamin 1-like -4.3645
MSN moesin -4.1223
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -4.07255
SGK1 serum/glucocorticoid regulated kinase 1 -3.9154
RBM34 RNA binding motif protein 34 -3.06452
ERGIC2 ERGIC and golgi 2 -2.93965
INTS13 integrator complex subunit 13 -2.9329
CAPRIN2 caprin family member 2 -2.78815
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase -2.6334
SINHCAF SIN3-HDAC complex associated factor -2.4934
ELOVL4 ELOVL fatty acid elongase 4 -2.4389
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -2.4339
NPPB natriuretic peptide B -2.2735
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) -2.23205
NMRK2 nicotinamide riboside kinase 2 -2.17375
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) -2.14345
HAPLN1 hyaluronan and proteoglycan link protein 1 -2.13438
MYH6 myosin, heavy chain 6, cardiac muscle, alpha -2.12902
ERCC6 excision repair cross-complementation group 6 -2.1287
BMAL2 basic helix-loop-helix ARNT like 2 -2.1176
STK38L serine/threonine kinase 38 like -2.1165
MED21 mediator complex subunit 21 -2.11543
SERGEF secretion regulating guanine nucleotide exchange factor -2.07055
POM121 POM121 transmembrane nucleoporin -2.045
PIWIL2 piwi-like RNA-mediated gene silencing 2 -2.03395
ZNF322 zinc finger protein 322 -2.0328