CRCGN017_MCF10A.WT.HP_24H:J16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p,p'-dichlorodiphenyl sulfone 100.8 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:J16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
E2F2 E2F transcription factor 2 4.80835
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 4.42173
GPATCH8 G patch domain containing 8 3.28962
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.07475
CNPY3 canopy FGF signaling regulator 3 2.92475
PECR peroxisomal trans-2-enoyl-CoA reductase 2.8649
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2 2.3252
GLI3 GLI family zinc finger 3 2.2373
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.2032
IHH indian hedgehog 2.1545
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.0829
EPPK1 epiplakin 1 2.0751
SNX11 sorting nexin 11 2.00155

decreased expression

Symbol Name Standardized Value
DERA deoxyribose-phosphate aldolase (putative) -5.2254
COPS7A COP9 signalosome subunit 7A -4.93985
CCDC86 coiled-coil domain containing 86 -4.6558
TES testin LIM domain protein -4.43328
MAPK13 mitogen-activated protein kinase 13 -4.38625
PHKA1 phosphorylase kinase, alpha 1 (muscle) -3.86085
LYPLA1 lysophospholipase I -3.44117
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.21068
SNX7 sorting nexin 7 -2.0651
MOXD1 monooxygenase, DBH-like 1 -2.04455
NAP1L4 nucleosome assembly protein 1-like 4 -2.01755