| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4-acetylaminobiphenyl 33.51 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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168 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:J20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| E2F2 | E2F transcription factor 2 | 5.2846 |
| KLHL21 | kelch-like family member 21 | 5.2456 |
| ABHD6 | abhydrolase domain containing 6 | 4.93962 |
| MAMLD1 | mastermind-like domain containing 1 | 4.79115 |
| WIF1 | WNT inhibitory factor 1 | 4.74185 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.7239 |
| MAP7 | microtubule-associated protein 7 | 4.54173 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.4629 |
| PRKCH | protein kinase C, eta | 4.34487 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 4.30212 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | 3.5556 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 3.09675 |
| ZNF556 | zinc finger protein 556 | 3.0402 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.97765 |
| RBKS | ribokinase | 2.95703 |
| OLFML2B | olfactomedin-like 2B | 2.929 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | 2.81215 |
| COQ8A | coenzyme Q8A | 2.71835 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.69102 |
| IFI27 | interferon, alpha-inducible protein 27 | 2.6664 |
| MAP2K3 | mitogen-activated protein kinase kinase 3 | 2.65692 |
| ZNF189 | zinc finger protein 189 | 2.6465 |
| SDF2 | stromal cell-derived factor 2 | 2.6399 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.62685 |
| SPAG5 | sperm associated antigen 5 | 2.61835 |
| METRN | meteorin, glial cell differentiation regulator | 2.5998 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.54575 |
| FLOT2 | flotillin 2 | 2.47092 |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 2.4606 |
| SESN1 | sestrin 1 | 2.4514 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 | 2.42235 |
| RBP1 | retinol binding protein 1, cellular | 2.4164 |
| MAOB | monoamine oxidase B | 2.40145 |
| TMEM9B | TMEM9 domain family, member B | 2.3565 |
| PDCD5 | programmed cell death 5 | 2.3458 |
| STIM1 | stromal interaction molecule 1 | 2.34335 |
| ABITRAM | actin binding transcription modulator | 2.34235 |
| RIC8B | RIC8 guanine nucleotide exchange factor B | 2.34115 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 | 2.3395 |
| TSPYL2 | TSPY-like 2 | 2.3385 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | 2.3294 |
| CRYAB | crystallin, alpha B | 2.31515 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 2.31425 |
| KXD1 | KxDL motif containing 1 | 2.29315 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 2.29205 |
| MCTS1 | malignant T cell amplified sequence 1 | 2.28895 |
| RWDD1 | RWD domain containing 1 | 2.27675 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 2.2764 |
| PENK | proenkephalin | 2.2628 |
| DCAF11 | DDB1 and CUL4 associated factor 11 | 2.25765 |
| NBAS | neuroblastoma amplified sequence | 2.25725 |
| EVX1 | even-skipped homeobox 1 | 2.2552 |
| ELAPOR1 | endosome-lysosome associated apoptosis and autophagy regulator 1 | 2.24945 |
| POLDIP2 | polymerase (DNA-directed), delta interacting protein 2 | 2.2381 |
| FKBP5 | FK506 binding protein 5 | 2.23775 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 2.23465 |
| KIF1B | kinesin family member 1B | 2.188 |
| SCRG1 | stimulator of chondrogenesis 1 | 2.1872 |
| UNC119B | unc-119 homolog B (C. elegans) | 2.16825 |
| EMD | emerin | 2.1614 |
| DERL2 | derlin 2 | 2.1527 |
| MVD | mevalonate (diphospho) decarboxylase | 2.14835 |
| OCEL1 | occludin/ELL domain containing 1 | 2.1279 |
| NDUFA8 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | 2.12005 |
| CIDEB | cell death-inducing DFFA-like effector b | 2.1073 |
| THBS4 | thrombospondin 4 | 2.10725 |
| TBX19 | T-box 19 | 2.1008 |
| TSPAN1 | tetraspanin 1 | 2.0939 |
| CD59 | CD59 molecule, complement regulatory protein | 2.09288 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 2.08327 |
| TRAF4 | TNF receptor-associated factor 4 | 2.07613 |
| F8 | coagulation factor VIII, procoagulant component | 2.06095 |
| HS1BP3 | HCLS1 binding protein 3 | 2.0596 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 | 2.0517 |
| DKK4 | dickkopf WNT signaling pathway inhibitor 4 | 2.0464 |
| PIERCE1 | piercer of microtubule wall 1 | 2.0462 |
| SNX3 | sorting nexin 3 | 2.0422 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | 2.03895 |
| HSPB2 | heat shock 27kDa protein 2 | 2.03455 |
| TFF1 | trefoil factor 1 | 2.03145 |
| HAVCR1 | hepatitis A virus cellular receptor 1 | 2.0289 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 2.0273 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 2.0249 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N | 2.01108 |
| BORCS6 | BLOC-1 related complex subunit 6 | 2.0108 |
| MXD1 | MAX dimerization protein 1 | 2.00925 |
| Symbol | Name | Standardized Value |
|---|---|---|
| S100A8 | S100 calcium binding protein A8 | -9.7285 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.20865 |
| NUP85 | nucleoporin 85kDa | -5.09175 |
| UFM1 | ubiquitin-fold modifier 1 | -4.9121 |
| PCNA | proliferating cell nuclear antigen | -4.75895 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -4.5797 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.2713 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.0924 |
| KCTD2 | potassium channel tetramerization domain containing 2 | -3.87038 |
| TMEM94 | transmembrane protein 94 | -3.59415 |
| NLRP4 | NLR family, pyrin domain containing 4 | -3.31715 |
| DIPK1A | divergent protein kinase domain 1A | -3.27073 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) | -3.04847 |
| PRCC | papillary renal cell carcinoma (translocation-associated) | -2.9789 |
| RAI14 | retinoic acid induced 14 | -2.89915 |
| ADPGK | ADP-dependent glucokinase | -2.8882 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit | -2.84628 |
| TENT4A | terminal nucleotidyltransferase 4A | -2.8058 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | -2.75905 |
| NGRN | neugrin, neurite outgrowth associated | -2.72405 |
| CD200 | CD200 molecule | -2.64252 |
| SMIM5 | small integral membrane protein 5 | -2.54885 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 | -2.50635 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.473 |
| ATG3 | autophagy related 3 | -2.46578 |
| TUBA4A | tubulin, alpha 4a | -2.4646 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.44975 |
| CHKB | choline kinase beta | -2.4464 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.4296 |
| MEFV | Mediterranean fever | -2.4282 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) | -2.42295 |
| SMAD7 | SMAD family member 7 | -2.4192 |
| ZNF12 | zinc finger protein 12 | -2.40555 |
| ADAMTSL3 | ADAMTS-like 3 | -2.39425 |
| KLHL3 | kelch-like family member 3 | -2.3801 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.3481 |
| PFN1 | profilin 1 | -2.32835 |
| NUDT15 | nudix (nucleoside diphosphate linked moiety X)-type motif 15 | -2.31955 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | -2.315 |
| FKBP4 | FK506 binding protein 4, 59kDa | -2.29562 |
| METTL3 | methyltransferase like 3 | -2.28597 |
| FAIM | Fas apoptotic inhibitory molecule | -2.2813 |
| NPTX1 | neuronal pentraxin I | -2.2569 |
| RAB23 | RAB23, member RAS oncogene family | -2.2163 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -2.19805 |
| NSUN5 | NOP2/Sun domain family, member 5 | -2.18712 |
| KCTD3 | potassium channel tetramerization domain containing 3 | -2.1809 |
| FAM193B | family with sequence similarity 193, member B | -2.1771 |
| PRPSAP1 | phosphoribosyl pyrophosphate synthetase-associated protein 1 | -2.1679 |
| PLCL1 | phospholipase C-like 1 | -2.16785 |
| DHX30 | DEAH (Asp-Glu-Ala-His) box helicase 30 | -2.1638 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 | -2.1622 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | -2.15045 |
| INSIG2 | insulin induced gene 2 | -2.13135 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -2.12593 |
| CDK3 | cyclin-dependent kinase 3 | -2.1244 |
| SAP30BP | SAP30 binding protein | -2.12085 |
| CDR2L | cerebellar degeneration-related protein 2-like | -2.1191 |
| CTSA | cathepsin A | -2.11705 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa | -2.10835 |
| SUCLA2 | succinate-CoA ligase, ADP-forming, beta subunit | -2.1078 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | -2.1012 |
| PGAP4 | post-GPI attachment to proteins GalNAc transferase 4 | -2.0768 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -2.07052 |
| DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | -2.0667 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -2.06247 |
| IER5 | immediate early response 5 | -2.0579 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -2.05465 |
| EVI2B | ecotropic viral integration site 2B | -2.0417 |
| RPH3A | rabphilin 3A | -2.04155 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -2.03977 |
| ZNF217 | zinc finger protein 217 | -2.03925 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -2.03275 |
| HPCAL1 | hippocalcin-like 1 | -2.02043 |
| LOC102723713 | TP53-target gene 3 protein | -2.0204 |
| FILIP1L | filamin A interacting protein 1-like | -2.02025 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -2.01666 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 | -2.01595 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -2.0151 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.0125 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) | -2.01242 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -2.0008 |
