CRCGN017_MCF10A.WT.HP_24H:K04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description glutaraldehyde 96.8 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:K04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 4.06329
ACAA1 acetyl-CoA acyltransferase 1 3.73792
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.66273
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 3.26078
LAGE3 L antigen family, member 3 3.13725
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.87448
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 2.81114
SNAP25 synaptosomal-associated protein, 25kDa 2.77704
TBX2 T-box 2 2.68324
COMP cartilage oligomeric matrix protein 2.6207
RAB31 RAB31, member RAS oncogene family 2.52842
MOCS3 molybdenum cofactor synthesis 3 2.52739
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.51202
ADAT1 adenosine deaminase, tRNA-specific 1 2.49909
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.28109
ZNF134 zinc finger protein 134 2.22885
ADAM15 ADAM metallopeptidase domain 15 2.11444
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.00958

decreased expression

Symbol Name Standardized Value
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.50778
PGAM4 phosphoglycerate mutase family member 4 -4.22443
BASP1 brain abundant, membrane attached signal protein 1 -4.11643
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.76584
KIF14 kinesin family member 14 -3.64468
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.5557
COPS7A COP9 signalosome subunit 7A -3.24263
PCCB propionyl CoA carboxylase, beta polypeptide -3.24014
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.80882
FPGS folylpolyglutamate synthase -2.36907
CD320 CD320 molecule -2.36554
ARID4A AT rich interactive domain 4A (RBP1-like) -2.24421
TGDS TDP-glucose 4,6-dehydratase -2.14281
TERF2 telomeric repeat binding factor 2 -2.0993
TMEM176A transmembrane protein 176A -2.07102
CCDC59 coiled-coil domain containing 59 -2.05745
CUEDC1 CUE domain containing 1 -2.0562
GDF15 growth differentiation factor 15 -2.01657
ARHGAP5 Rho GTPase activating protein 5 -2.01089