CRCGN017_MCF10A.WT.HP_24H:K05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description glutaraldehyde 32.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:K05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.70453
FZD1 frizzled class receptor 1 2.55436
PROS1 protein S (alpha) 2.51131
KDM5D lysine (K)-specific demethylase 5D 2.46062
USP9Y ubiquitin specific peptidase 9, Y-linked 2.4075
PPARG peroxisome proliferator-activated receptor gamma 2.25216
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.17705
ABHD6 abhydrolase domain containing 6 2.10496

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -8.85798
GDF15 growth differentiation factor 15 -4.93688
ISOC1 isochorismatase domain containing 1 -4.71647
KRT14 keratin 14, type I -3.47372
MSMO1 methylsterol monooxygenase 1 -3.03752
PPIC peptidylprolyl isomerase C (cyclophilin C) -2.93898
SMC1A structural maintenance of chromosomes 1A -2.7524
PUF60 poly-U binding splicing factor 60KDa -2.71692
MSN moesin -2.66924
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.57413
ARID4B AT rich interactive domain 4B (RBP1-like) -2.42211
TNIP1 TNFAIP3 interacting protein 1 -2.36882
KIF14 kinesin family member 14 -2.34145
TBPL1 TBP-like 1 -2.21429
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.14658
RXYLT1 ribitol xylosyltransferase 1 -2.14496
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.09302
TRIM37 tripartite motif containing 37 -2.059
USP9X ubiquitin specific peptidase 9, X-linked -2.03477