CRCGN017_MCF10A.WT.HP_24H:K06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description glutaraldehyde 10.76 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:K06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 5.46211
CCP110 centriolar coiled coil protein 110kDa 5.04754
HMOX1 heme oxygenase 1 5.01597
FGFR4 fibroblast growth factor receptor 4 4.04981
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.76625
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) 2.69696
AAMDC adipogenesis associated, Mth938 domain containing 2.56463
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.45576
PKN1 protein kinase N1 2.35302
GAB2 GRB2-associated binding protein 2 2.28651
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.25143
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 2.15261

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -6.17765
GDF15 growth differentiation factor 15 -4.84654
HMG20B high mobility group 20B -4.75291
PCNA proliferating cell nuclear antigen -4.02013
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.63948
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.31084
PTK2 protein tyrosine kinase 2 -3.29477
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.49283
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.34462
NGRN neugrin, neurite outgrowth associated -2.20987
CBX4 chromobox homolog 4 -2.12974
ARID4B AT rich interactive domain 4B (RBP1-like) -2.09058
ADAM23 ADAM metallopeptidase domain 23 -2.08112
KRT14 keratin 14, type I -2.069
ZFHX3 zinc finger homeobox 3 -2.03609
ANKRD10 ankyrin repeat domain 10 -2.00651
SMYD3 SET and MYND domain containing 3 -2.00297