CRCGN017_MCF10A.WT.HP_24H:K13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acrylamide 100.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:K13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 5.51795
TLR4 toll-like receptor 4 4.39315
BID BH3 interacting domain death agonist 3.46518
WIF1 WNT inhibitory factor 1 3.16115
JADE1 jade family PHD finger 1 2.81185
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.73492
CD70 CD70 molecule 2.31365
COQ8A coenzyme Q8A 2.3029
IL17RA interleukin 17 receptor A 2.1779
ACSL1 acyl-CoA synthetase long-chain family member 1 2.04378
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) 2.03275

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -5.0
CCNB2 cyclin B2 -4.66275
NPDC1 neural proliferation, differentiation and control, 1 -4.54065
PCCB propionyl CoA carboxylase, beta polypeptide -3.6817
SGK1 serum/glucocorticoid regulated kinase 1 -3.51175
SMNDC1 survival motor neuron domain containing 1 -3.3968
ARPP19 cAMP-regulated phosphoprotein, 19kDa -3.06925
DCK deoxycytidine kinase -2.9701
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.61045
KRT14 keratin 14, type I -2.4538
FOS FBJ murine osteosarcoma viral oncogene homolog -2.40245
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -2.3635
SNX7 sorting nexin 7 -2.36095
POLR2M polymerase (RNA) II (DNA directed) polypeptide M -2.09935
RNF111 ring finger protein 111 -2.0694
S100A8 S100 calcium binding protein A8 -2.05315
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -2.00045