CRCGN017_MCF10A.WT.HP_24H:K15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acrylamide 11.14 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:K15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 5.3928
SNAP25 synaptosomal-associated protein, 25kDa 5.0401
CNRIP1 cannabinoid receptor interacting protein 1 4.9246
CXCL2 chemokine (C-X-C motif) ligand 2 4.73365
AXIN1 axin 1 3.93895
UGDH UDP-glucose 6-dehydrogenase 3.58555
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 3.00183
NEFL neurofilament, light polypeptide 2.33588
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 2.2557
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 2.24475
NEFM neurofilament, medium polypeptide 2.1711
MGP matrix Gla protein 2.13655
INTS3 integrator complex subunit 3 2.1163
STMN2 stathmin 2 2.03457

decreased expression

Symbol Name Standardized Value
SGK1 serum/glucocorticoid regulated kinase 1 -5.0
BAG3 BCL2-associated athanogene 3 -4.9565
ADI1 acireductone dioxygenase 1 -4.774
S100A8 S100 calcium binding protein A8 -4.51505
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.47245
NPDC1 neural proliferation, differentiation and control, 1 -4.26345
PCCB propionyl CoA carboxylase, beta polypeptide -3.98045
RNF167 ring finger protein 167 -3.67115
TRAPPC3 trafficking protein particle complex 3 -3.47007
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.98045
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.8174
BASP1 brain abundant, membrane attached signal protein 1 -2.75705
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.70117
CCND3 cyclin D3 -2.6643
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.36775
SMC4 structural maintenance of chromosomes 4 -2.293
VAV1 vav 1 guanine nucleotide exchange factor -2.204
KAT2A K(lysine) acetyltransferase 2A -2.14535
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.0735
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 -2.0422
SAYSD1 SAYSVFN motif domain containing 1 -2.03375