CRCGN017_MCF10A.WT.HP_24H:K18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-aminoanthracene 11.26 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

672 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:K18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 10.0
WIF1 WNT inhibitory factor 1 6.6682
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 5.18225
ABHD4 abhydrolase domain containing 4 5.1302
KLHL21 kelch-like family member 21 5.0
CXCL2 chemokine (C-X-C motif) ligand 2 4.81905
NANOS3 nanos homolog 3 (Drosophila) 4.7293
GSTM2 glutathione S-transferase mu 2 (muscle) 4.67237
EGF epidermal growth factor 4.57905
NEFM neurofilament, medium polypeptide 4.50025
VSNL1 visinin-like 1 4.38383
SYN1 synapsin I 4.2404
NEFL neurofilament, light polypeptide 4.19525
SYT2 synaptotagmin II 4.182
ANO10 anoctamin 10 4.1165
NSG2 neuronal vesicle trafficking associated 2 3.98675
MELTF melanotransferrin 3.92785
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 3.89509
MED24 mediator complex subunit 24 3.88795
BARX2 BARX homeobox 2 3.80565
HLA-DRA major histocompatibility complex, class II, DR alpha 3.79887
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 3.7865
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.77257
PARP3 poly (ADP-ribose) polymerase family, member 3 3.7054
CNPY3 canopy FGF signaling regulator 3 3.70055
RGS7 regulator of G-protein signaling 7 3.69025
ZNF571 zinc finger protein 571 3.6694
HCLS1 hematopoietic cell-specific Lyn substrate 1 3.66695
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.62435
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 3.61215
FAR2 fatty acyl CoA reductase 2 3.57285
MOK MOK protein kinase 3.5717
PADI1 peptidyl arginine deiminase, type I 3.5561
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 3.53975
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 3.53495
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3.4734
COQ8A coenzyme Q8A 3.4584
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 3.42485
REEP2 receptor accessory protein 2 3.41665
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 3.37705
GET1 guided entry of tail-anchored proteins factor 1 3.3539
RPL39L ribosomal protein L39-like 3.30725
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 3.30035
DOK2 docking protein 2, 56kDa 3.2966
SATB1 SATB homeobox 1 3.29295
CMTR1 cap methyltransferase 1 3.28575
SARS2 seryl-tRNA synthetase 2, mitochondrial 3.27845
TRPM2 transient receptor potential cation channel, subfamily M, member 2 3.24555
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1 3.22455
SNAP91 synaptosomal-associated protein, 91kDa 3.2162
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 3.1972
LAG3 lymphocyte-activation gene 3 3.1889
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase 3.18625
FGGY FGGY carbohydrate kinase domain containing 3.142
KPTN kaptin (actin binding protein) 3.1364
CTNNA2 catenin (cadherin-associated protein), alpha 2 3.1342
EPHB3 EPH receptor B3 3.12525
GRIA2 glutamate receptor, ionotropic, AMPA 2 3.1213
CIB2 calcium and integrin binding family member 2 3.11625
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 3.0977
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 3.0928
SDHAF1 succinate dehydrogenase complex assembly factor 1 3.07177
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 3.0698
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 3.06465
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 3.06055
GSTA4 glutathione S-transferase alpha 4 3.0555
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2 3.05535
CBLN1 cerebellin 1 precursor 3.03805
DLL3 delta-like 3 (Drosophila) 3.02125
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 3.0168
TCEAL1 transcription elongation factor A (SII)-like 1 3.0028
XYLT1 xylosyltransferase I 3.0025
CPED1 cadherin-like and PC-esterase domain containing 1 3.00015
SNCB synuclein, beta 3.0
HAPSTR1 HUWE1 associated protein modifying stress responses 2.9936
ELOVL2 ELOVL fatty acid elongase 2 2.98772
CARTPT CART prepropeptide 2.9876
ANGPT1 angiopoietin 1 2.9812
CDH18 cadherin 18, type 2 2.96565
DGKG diacylglycerol kinase, gamma 90kDa 2.9477
CKB creatine kinase, brain 2.94045
CADPS2 Ca++-dependent secretion activator 2 2.93975
CLCNKA chloride channel, voltage-sensitive Ka 2.9365
E2F6 E2F transcription factor 6 2.9298
ZNF518A zinc finger protein 518A 2.9288
ATF5 activating transcription factor 5 2.9274
NRCAM neuronal cell adhesion molecule 2.91045
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 2.90715
IL26 interleukin 26 2.9048
ADGRL3 adhesion G protein-coupled receptor L3 2.90077
SYT1 synaptotagmin I 2.89975
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.89475
CCDC85B coiled-coil domain containing 85B 2.8911
LOC124907090 ankyrin repeat domain-containing protein SOWAHC-like 2.8873
OPCML opioid binding protein/cell adhesion molecule-like 2.8865
HBB hemoglobin, beta 2.8852
STMN2 stathmin 2 2.85995
AMPH amphiphysin 2.85805
ANK1 ankyrin 1, erythrocytic 2.85333
ZC4H2 zinc finger, C4H2 domain containing 2.8457
TUBB4A tubulin, beta 4A class IVa 2.84295
PPP1R12B protein phosphatase 1, regulatory subunit 12B 2.841
SAE1 SUMO1 activating enzyme subunit 1 2.834
ATL2 atlastin GTPase 2 2.8302
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 2.82265
CT55 cancer/testis antigen 55 2.8203
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 2.818
CLDN8 claudin 8 2.81725
ZNF428 zinc finger protein 428 2.81695
CALCA calcitonin-related polypeptide alpha 2.80411
IL13 interleukin 13 2.8035
SDHAF3 succinate dehydrogenase complex assembly factor 3 2.79305
BAG4 BCL2-associated athanogene 4 2.79035
DUSP2 dual specificity phosphatase 2 2.7823
RGN regucalcin 2.7683
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 2.76525
PRELID3A PRELI domain containing 3A 2.76335
GRHL2 grainyhead-like 2 (Drosophila) 2.7595
FBXO40 F-box protein 40 2.7555
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.75087
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 2.7447
GCLM glutamate-cysteine ligase, modifier subunit 2.74365
CAPN6 calpain 6 2.74047
TENM1 teneurin transmembrane protein 1 2.7258
SV2B synaptic vesicle glycoprotein 2B 2.7246
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 2.72175
MCOLN1 mucolipin 1 2.7192
AMDHD2 amidohydrolase domain containing 2 2.717
RUNDC3A RUN domain containing 3A 2.71535
HSPB6 heat shock protein, alpha-crystallin-related, B6 2.7151
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 2.7075
ZNF280A zinc finger protein 280A 2.707
CCL1 chemokine (C-C motif) ligand 1 2.70275
ACTL6B actin-like 6B 2.69715
CD34 CD34 molecule 2.69405
PI15 peptidase inhibitor 15 2.69365
BIN2 bridging integrator 2 2.69195
DRC9 dynein regulatory complex subunit 9 2.6864
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.68285
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 2.68088
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 2.6761
LGSN lengsin, lens protein with glutamine synthetase domain 2.6752
PYCR1 pyrroline-5-carboxylate reductase 1 2.6751
ZNF589 zinc finger protein 589 2.67397
SSBP3 single stranded DNA binding protein 3 2.6724
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 2.66565
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.6641
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11 2.66265
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 2.6593
ARHGAP24 Rho GTPase activating protein 24 2.65675
GCLC glutamate-cysteine ligase, catalytic subunit 2.64885
CNTFR ciliary neurotrophic factor receptor 2.64845
KCTD14 potassium channel tetramerization domain containing 14 2.648
PCNT pericentrin 2.6458
PRPF31 pre-mRNA processing factor 31 2.64435
PLA2G15 phospholipase A2, group XV 2.63825
SSUH2 ssu-2 homolog (C. elegans) 2.6376
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 2.63602
CLIP3 CAP-GLY domain containing linker protein 3 2.62725
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 2.61915
APLNR apelin receptor 2.61495
FAF1 Fas (TNFRSF6) associated factor 1 2.6127
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 2.6102
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 2.6089
ARB2A ARB2 cotranscriptional regulator A 2.60465
CA14 carbonic anhydrase XIV 2.60395
CALB1 calbindin 1, 28kDa 2.6003
SPTBN4 spectrin, beta, non-erythrocytic 4 2.5963
TMEM168 transmembrane protein 168 2.5949
COL1A2 collagen, type I, alpha 2 2.59065
ATP8B4 ATPase, class I, type 8B, member 4 2.5899
RPH3A rabphilin 3A 2.58895
MYBPC1 myosin binding protein C, slow type 2.5817
TBXT T-box transcription factor T 2.57995
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.57745
CRYAB crystallin, alpha B 2.5763
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.57625
GRM4 glutamate receptor, metabotropic 4 2.57015
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 2.56952
NECTIN4 nectin cell adhesion molecule 4 2.5646
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2.56195
NDRG4 NDRG family member 4 2.55885
LOC124907012 endogenous retrovirus group K member 7 Env polyprotein-like 2.5564
IRF6 interferon regulatory factor 6 2.55615
ICAM1 intercellular adhesion molecule 1 2.55607
MXD3 MAX dimerization protein 3 2.55455
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 2.55295
FES FES proto-oncogene, tyrosine kinase 2.55065
MTSS2 MTSS I-BAR domain containing 2 2.5493
DENND1C DENN/MADD domain containing 1C 2.5474
TAGLN3 transgelin 3 2.54655
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 2.54532
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.54515
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.5426
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 2.53705
CTF1 cardiotrophin 1 2.536
SOCS1 suppressor of cytokine signaling 1 2.53258
CCHCR1 coiled-coil alpha-helical rod protein 1 2.5265
ACSS3 acyl-CoA synthetase short-chain family member 3 2.52415
CCDC81 coiled-coil domain containing 81 2.52385
CD8A CD8a molecule 2.52165
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 2.5212
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 2.5172
EGLN1 egl-9 family hypoxia-inducible factor 1 2.51685
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 2.51358
CCDC91 coiled-coil domain containing 91 2.5124
CAMKMT calmodulin-lysine N-methyltransferase 2.51155
ODAM odontogenic, ameloblast asssociated 2.50865
GUF1 GUF1 GTPase homolog (S. cerevisiae) 2.50695
NXT2 nuclear transport factor 2-like export factor 2 2.50467
RALYL RALY RNA binding protein-like 2.50345
SSX2 synovial sarcoma, X breakpoint 2 2.50313
GFI1 growth factor independent 1 transcription repressor 2.49815
PLXND1 plexin D1 2.497
NT5DC2 5'-nucleotidase domain containing 2 2.49595
PLA2G2D phospholipase A2, group IID 2.49485
MSX1 msh homeobox 1 2.4942
RNF31 ring finger protein 31 2.4919
F2R coagulation factor II (thrombin) receptor 2.48885
CD248 CD248 molecule, endosialin 2.48695
NPPA natriuretic peptide A 2.48205
FAM184A family with sequence similarity 184, member A 2.47995
NECAB3 N-terminal EF-hand calcium binding protein 3 2.4777
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 2.4723
MNS1 meiosis-specific nuclear structural 1 2.4638
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2.4626
DIABLO diablo, IAP-binding mitochondrial protein 2.4619
CLCNKB chloride channel, voltage-sensitive Kb 2.4597
IL2RB interleukin 2 receptor, beta 2.459
UNC13D unc-13 homolog D (C. elegans) 2.4583
BPIFA1 BPI fold containing family A, member 1 2.45645
CASC3 cancer susceptibility candidate 3 2.45525
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 2.45505
IFNA13 interferon, alpha 13 2.4548
CASR calcium-sensing receptor 2.45405
GLRA2 glycine receptor, alpha 2 2.44795
INA internexin neuronal intermediate filament protein, alpha 2.4479
SPATS2 spermatogenesis associated, serine-rich 2 2.4478
EFNA3 ephrin-A3 2.44255
TCN2 transcobalamin II 2.4406
ELF2 E74-like factor 2 (ets domain transcription factor) 2.43942
KLHL11 kelch-like family member 11 2.4372
PCBP4 poly(rC) binding protein 4 2.43635
ZNF223 zinc finger protein 223 2.4315
KLHDC3 kelch domain containing 3 2.43097
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 2.43045
ACYP2 acylphosphatase 2, muscle type 2.42965
MYT1L myelin transcription factor 1-like 2.42548
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2 2.42455
GYG1 glycogenin 1 2.42322
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma 2.41715
SCN1B sodium channel, voltage gated, type I beta subunit 2.41665
SNX16 sorting nexin 16 2.4144
GSTM5 glutathione S-transferase mu 5 2.4119
CRTAM cytotoxic and regulatory T cell molecule 2.4072
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 2.40445
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 2.4031
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 2.4026
SCG3 secretogranin III 2.4025
TPSG1 tryptase gamma 1 2.40125
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 2.40065
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 2.39925
YJU2B YJU2 splicing factor homolog B 2.3962
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 2.39305
MIIP migration and invasion inhibitory protein 2.3916
CLCN5 chloride channel, voltage-sensitive 5 2.3869
ADGRE1 adhesion G protein-coupled receptor E1 2.38665
MUC7 mucin 7, secreted 2.3863
VASP vasodilator-stimulated phosphoprotein 2.38525
ARRB1 arrestin, beta 1 2.38425
EEF2 eukaryotic translation elongation factor 2 2.38298
SOCS6 suppressor of cytokine signaling 6 2.37893
NR1D1 nuclear receptor subfamily 1, group D, member 1 2.3756
FAM120C family with sequence similarity 120C 2.37455
HSF2 heat shock transcription factor 2 2.37367
AQP4 aquaporin 4 2.37181
ZFP37 ZFP37 zinc finger protein 2.3638
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 2.36205
PHKG1 phosphorylase kinase, gamma 1 (muscle) 2.362
PCDHB3 protocadherin beta 3 2.35775
OR52A1 olfactory receptor, family 52, subfamily A, member 1 2.35395
CLEC1A C-type lectin domain family 1, member A 2.35355
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 2.35305
CXCL3 chemokine (C-X-C motif) ligand 3 2.3528
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 2.3525
NXPH3 neurexophilin 3 2.344
CRYM crystallin, mu 2.3428
CLDN15 claudin 15 2.34225
PTPN6 protein tyrosine phosphatase, non-receptor type 6 2.34205
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.3381
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z 2.338
APOD apolipoprotein D 2.33795
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 2.3359
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 2.334
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.33253
GSK3A glycogen synthase kinase 3 alpha 2.3316
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 2.32915
ZIC1 Zic family member 1 2.32895
TRAP1 TNF receptor-associated protein 1 2.32555
SIRPG signal-regulatory protein gamma 2.3227
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 2.32081
SASH1 SAM and SH3 domain containing 1 2.3208
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 2.3189
PROX1 prospero homeobox 1 2.31755
ZNF8 zinc finger protein 8 2.31235
MYOM2 myomesin 2 2.31125
CPPED1 calcineurin-like phosphoesterase domain containing 1 2.31015
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.309
KEAP1 kelch-like ECH-associated protein 1 2.3061
PGC progastricsin (pepsinogen C) 2.3054
TSPOAP1 TSPO associated protein 1 2.3046
PPP2R5D protein phosphatase 2, regulatory subunit B', delta 2.30338
ACTG2 actin, gamma 2, smooth muscle, enteric 2.30095
SASH3 SAM and SH3 domain containing 3 2.29915
FABP3 fatty acid binding protein 3, muscle and heart 2.29315
HOXA2 homeobox A2 2.2882
CD8B CD8b molecule 2.2882
TLX1 T-cell leukemia homeobox 1 2.28005
RHBG Rh family, B glycoprotein (gene/pseudogene) 2.28
RAB27A RAB27A, member RAS oncogene family 2.27933
SLC39A7 solute carrier family 39 (zinc transporter), member 7 2.2724
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 2.2723
MECR mitochondrial trans-2-enoyl-CoA reductase 2.2722
PRPSAP1 phosphoribosyl pyrophosphate synthetase-associated protein 1 2.2718
ERCC2 excision repair cross-complementation group 2 2.2675
WWOX WW domain containing oxidoreductase 2.26663
CNGA3 cyclic nucleotide gated channel alpha 3 2.2664
VWA8 von Willebrand factor A domain containing 8 2.2641
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 2.262
SETBP1 SET binding protein 1 2.26135
ZNF614 zinc finger protein 614 2.25793
ZNF10 zinc finger protein 10 2.2566
ZNF280B zinc finger protein 280B 2.25545
TMEM242 transmembrane protein 242 2.2527
SOCS3 suppressor of cytokine signaling 3 2.25105
KIF5A kinesin family member 5A 2.25025
HOXC5 homeobox C5 2.24825
CAMK2B calcium/calmodulin-dependent protein kinase II beta 2.24767
ITPKC inositol-trisphosphate 3-kinase C 2.2474
ZMYM5 zinc finger, MYM-type 5 2.24573
SEZ6L seizure related 6 homolog (mouse)-like 2.24542
CDKN2A cyclin-dependent kinase inhibitor 2A 2.24505
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 2.24407
FAT1 FAT atypical cadherin 1 2.2423
PRDM13 PR domain containing 13 2.2418
GALK1 galactokinase 1 2.24
ZNF768 zinc finger protein 768 2.2366
SSX5 synovial sarcoma, X breakpoint 5 2.2354
OR7A5 olfactory receptor, family 7, subfamily A, member 5 2.23425
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 2.23315
FBXO22 F-box protein 22 2.2322
PPP5C protein phosphatase 5, catalytic subunit 2.232
AQP2 aquaporin 2 (collecting duct) 2.23145
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 2.22955
HDAC11 histone deacetylase 11 2.2294
HOXC8 homeobox C8 2.2293
MAGEA10 melanoma antigen family A10 2.2252
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 2.22097
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 2.21962
SCGN secretagogin, EF-hand calcium binding protein 2.21725
MYOZ1 myozenin 1 2.2122
CHGB chromogranin B 2.2096
NUCB2 nucleobindin 2 2.20425
GYPC glycophorin C (Gerbich blood group) 2.20345
CTNNA3 catenin (cadherin-associated protein), alpha 3 2.1999
CADM4 cell adhesion molecule 4 2.19675
ARID3A AT rich interactive domain 3A (BRIGHT-like) 2.1962
CLASRP CLK4-associating serine/arginine rich protein 2.195
PLP1 proteolipid protein 1 2.19405
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 2.18788
PPP4R3B protein phosphatase 4 regulatory subunit 3B 2.18555
RENBP renin binding protein 2.1847
ASIC1 acid sensing (proton gated) ion channel 1 2.18467
TGM5 transglutaminase 5 2.1843
PAQR6 progestin and adipoQ receptor family member VI 2.18305
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 2.17845
TAC1 tachykinin, precursor 1 2.17475
RRAGB Ras-related GTP binding B 2.1745
TBX21 T-box 21 2.17355
FGF9 fibroblast growth factor 9 2.17355
PNMA2 paraneoplastic Ma antigen 2 2.17245
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.17195
CDK19 cyclin-dependent kinase 19 2.17158
PCSK1 proprotein convertase subtilisin/kexin type 1 2.16815
ITGA9 integrin, alpha 9 2.1659
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 2.16065
MAGEA2B melanoma antigen family A2B 2.15595
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 2.15385
S100B S100 calcium binding protein B 2.1538
PLAC1 placenta-specific 1 2.1523
LIN7B lin-7 homolog B (C. elegans) 2.1512
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 2.1506
PCDHGA5 protocadherin gamma subfamily A, 5 2.1502
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 2.1472
SORBS1 sorbin and SH3 domain containing 1 2.1467
ZNF266 zinc finger protein 266 2.1396
DTNA dystrobrevin, alpha 2.13922
NIPSNAP1 nipsnap homolog 1 (C. elegans) 2.139
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.13695
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 2.1357
PDE4D phosphodiesterase 4D, cAMP-specific 2.13549
DIXDC1 DIX domain containing 1 2.13535
BCL2L10 BCL2-like 10 (apoptosis facilitator) 2.1324
MTA2 metastasis associated 1 family, member 2 2.13185
ZNF219 zinc finger protein 219 2.1316
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 2.13105
UBE2M ubiquitin-conjugating enzyme E2M 2.1298
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 2.12945
GNG4 guanine nucleotide binding protein (G protein), gamma 4 2.1252
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 2.1251
A4GALT alpha 1,4-galactosyltransferase 2.1224
STATH statherin 2.1221
NLRP2 NLR family, pyrin domain containing 2 2.1195
IFT52 intraflagellar transport 52 2.1192
PIGR polymeric immunoglobulin receptor 2.11905
SRR serine racemase 2.11893
SSX4B synovial sarcoma, X breakpoint 4B 2.11559
DENND4B DENN/MADD domain containing 4B 2.11165
PAX6 paired box 6 2.11155
CD226 CD226 molecule 2.10485
TRAPPC11 trafficking protein particle complex 11 2.10215
THAP3 THAP domain containing, apoptosis associated protein 3 2.1012
MANEA mannosidase, endo-alpha 2.10095
NREP neuronal regeneration related protein 2.09693
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.0968
RFX7 regulatory factor X, 7 2.0967
ZNF205 zinc finger protein 205 2.0965
CAPNS1 calpain, small subunit 1 2.0955
DMD dystrophin 2.09513
NECTIN2 nectin cell adhesion molecule 2 2.0936
HSPA2 heat shock 70kDa protein 2 2.093
RNF122 ring finger protein 122 2.09255
WNT8B wingless-type MMTV integration site family, member 8B 2.0919
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 2.09185
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.0907
CNTLN centlein, centrosomal protein 2.08885
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.08875
ZNF263 zinc finger protein 263 2.08835
CORO1A coronin, actin binding protein, 1A 2.08575
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 2.08495
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 2.0839
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa 2.08325
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 2.08253
MPZ myelin protein zero 2.08192
PRUNE2 prune homolog 2 (Drosophila) 2.08065
SSX3 synovial sarcoma, X breakpoint 3 2.0805
LTN1 listerin E3 ubiquitin protein ligase 1 2.0785
AMBN ameloblastin (enamel matrix protein) 2.0779
GSTM4 glutathione S-transferase mu 4 2.07762
STXBP5L syntaxin binding protein 5-like 2.07685
CLSTN3 calsyntenin 3 2.07645
TCHH trichohyalin 2.07495
TBC1D17 TBC1 domain family, member 17 2.07385
GRAMD4 GRAM domain containing 4 2.07365
ZNF236 zinc finger protein 236 2.07288
DRD5 dopamine receptor D5 2.07165
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 2.0713
ZNF133 zinc finger protein 133 2.07125
ST18 suppression of tumorigenicity 18, zinc finger 2.0687
PRH1 proline-rich protein HaeIII subfamily 1 2.068
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 2.06798
CDADC1 cytidine and dCMP deaminase domain containing 1 2.06625
ANKRD44 ankyrin repeat domain 44 2.0661
KRT9 keratin 9, type I 2.0655
CTNNBIP1 catenin, beta interacting protein 1 2.06405
CD3D CD3d molecule, delta (CD3-TCR complex) 2.06365
MAP1B microtubule-associated protein 1B 2.05982
APLP1 amyloid beta (A4) precursor-like protein 1 2.05975
FNDC4 fibronectin type III domain containing 4 2.0577
MRAS muscle RAS oncogene homolog 2.05695
RFXAP regulatory factor X-associated protein 2.05635
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 2.0558
STIM1 stromal interaction molecule 1 2.05295
LCN1 lipocalin 1 2.05145
CD33 CD33 molecule 2.05025
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.0496
RRH retinal pigment epithelium-derived rhodopsin homolog 2.04845
MAP3K8 mitogen-activated protein kinase kinase kinase 8 2.04815
ZNF761 zinc finger protein 761 2.04745
DPP6 dipeptidyl-peptidase 6 2.0469
BCL2L14 BCL2-like 14 (apoptosis facilitator) 2.04595
ASCL1 achaete-scute family bHLH transcription factor 1 2.04523
HOPX HOP homeobox 2.04515
PRR14L proline rich 14-like 2.0444
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 2.04285
SV2A synaptic vesicle glycoprotein 2A 2.04015
ZNF419 zinc finger protein 419 2.03767
PPP1R9B protein phosphatase 1, regulatory subunit 9B 2.0365
MTMR14 myotubularin related protein 14 2.0363
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 2.0303
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 2.0302
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4 2.02945
TMEM151B transmembrane protein 151B 2.0293
NKG7 natural killer cell granule protein 7 2.02895
CRIPT cysteine-rich PDZ-binding protein 2.0259
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.0251
TPH1 tryptophan hydroxylase 1 2.024
EN2 engrailed homeobox 2 2.01815
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 2.0159
CGREF1 cell growth regulator with EF-hand domain 1 2.01425
AP5S1 adaptor-related protein complex 5, sigma 1 subunit 2.0125
STK11 serine/threonine kinase 11 2.01242
ZKSCAN8 zinc finger with KRAB and SCAN domains 8 2.0115
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.01085
KCTD11 potassium channel tetramerization domain containing 11 2.0108
RAB4B RAB4B, member RAS oncogene family 2.01055
CASS4 Cas scaffolding protein family member 4 2.00975
GPR52 G protein-coupled receptor 52 2.0084
CEP76 centrosomal protein 76kDa 2.00513
XPA xeroderma pigmentosum, complementation group A 2.00405
GPR22 G protein-coupled receptor 22 2.00165
BCL2 B-cell CLL/lymphoma 2 2.00063

decreased expression

Symbol Name Standardized Value
DSG2 desmoglein 2 -7.2903
SGK1 serum/glucocorticoid regulated kinase 1 -5.39525
HAT1 histone acetyltransferase 1 -5.3006
SLC35F2 solute carrier family 35, member F2 -5.24955
MT2A metallothionein 2A -5.14035
MRPS16 mitochondrial ribosomal protein S16 -4.806
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.7011
YME1L1 YME1-like 1 ATPase -4.63172
CAB39 calcium binding protein 39 -4.57525
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -4.54775
CCNB2 cyclin B2 -4.3865
STXBP2 syntaxin binding protein 2 -4.3803
MRPS2 mitochondrial ribosomal protein S2 -4.37335
MSN moesin -4.22105
NUP93 nucleoporin 93kDa -3.9062
ANXA3 annexin A3 -3.7203
FCHO1 FCH domain only 1 -3.68425
SARAF store-operated calcium entry-associated regulatory factor -3.6596
KRT14 keratin 14, type I -3.63215
HMG20B high mobility group 20B -3.61895
BID BH3 interacting domain death agonist -3.49335
ELAC2 elaC ribonuclease Z 2 -3.4803
CD58 CD58 molecule -3.39678
WASHC4 WASH complex subunit 4 -3.33955
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -3.3155
MSMO1 methylsterol monooxygenase 1 -3.29985
CREB3L4 cAMP responsive element binding protein 3-like 4 -3.0939
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 -3.028
SGCE sarcoglycan, epsilon -3.0023
CIB1 calcium and integrin binding 1 (calmyrin) -2.92595
TMEM208 transmembrane protein 208 -2.9192
HSPA1A heat shock 70kDa protein 1A -2.9067
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32 -2.9022
SURF2 surfeit 2 -2.8958
TOMM34 translocase of outer mitochondrial membrane 34 -2.88885
MMD monocyte to macrophage differentiation-associated -2.87745
MTERF3 mitochondrial transcription termination factor 3 -2.8719
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) -2.85605
RPA3 replication protein A3, 14kDa -2.84675
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.7942
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) -2.7349
EXOSC4 exosome component 4 -2.72715
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.7229
RNF111 ring finger protein 111 -2.71915
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -2.70745
ZWILCH zwilch kinetochore protein -2.6784
MRPS31 mitochondrial ribosomal protein S31 -2.65408
COPS7A COP9 signalosome subunit 7A -2.6492
TM9SF2 transmembrane 9 superfamily member 2 -2.6257
SAR1A secretion associated, Ras related GTPase 1A -2.61372
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -2.6112
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -2.6082
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 -2.60505
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.58278
CANX calnexin -2.5609
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.51575
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.5125
SHTN1 shootin 1 -2.50735
TOM1L1 target of myb1 (chicken)-like 1 -2.4656
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -2.4566
EPHA2 EPH receptor A2 -2.44985
WDR3 WD repeat domain 3 -2.4473
MISP mitotic spindle positioning -2.41765
MRPS17 mitochondrial ribosomal protein S17 -2.4169
PRKX protein kinase, X-linked -2.41302
MCTS1 malignant T cell amplified sequence 1 -2.41095
RIGI RNA sensor RIG-I -2.41035
MT1X metallothionein 1X -2.41033
PPP1R26 protein phosphatase 1, regulatory subunit 26 -2.4086
KIF2C kinesin family member 2C -2.40418
CTSK cathepsin K -2.3826
CAMLG calcium modulating ligand -2.37845
ADGRG6 adhesion G protein-coupled receptor G6 -2.3732
VAMP8 vesicle-associated membrane protein 8 -2.36675
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -2.3603
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.35515
UFM1 ubiquitin-fold modifier 1 -2.3439
FOXF2 forkhead box F2 -2.3431
ATP5IF1 ATP synthase inhibitory factor subunit 1 -2.34295
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.3346
TGDS TDP-glucose 4,6-dehydratase -2.31965
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -2.3103
DCAF10 DDB1 and CUL4 associated factor 10 -2.3084
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) -2.3055
TBPL1 TBP-like 1 -2.30525
DOCK1 dedicator of cytokinesis 1 -2.3028
ANKRD10 ankyrin repeat domain 10 -2.3011
ZHX2 zinc fingers and homeoboxes 2 -2.292
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.26622
ZC2HC1A zinc finger, C2HC-type containing 1A -2.2569
IL7R interleukin 7 receptor -2.2512
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 -2.25025
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -2.2388
ISOC1 isochorismatase domain containing 1 -2.23605
AUP1 ancient ubiquitous protein 1 -2.23415
RARS1 arginyl-tRNA synthetase 1 -2.23045
SAP30L SAP30-like -2.21295
ULBP2 UL16 binding protein 2 -2.19555
RGS2 regulator of G-protein signaling 2 -2.1912
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -2.1862
SCUBE2 signal peptide, CUB domain, EGF-like 2 -2.18455
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 -2.181
GALT galactose-1-phosphate uridylyltransferase -2.1705
PWWP3A PWWP domain containing 3A, DNA repair factor -2.1572
CERS2 ceramide synthase 2 -2.1444
COL10A1 collagen, type X, alpha 1 -2.14202
FAIM Fas apoptotic inhibitory molecule -2.14105
ARHGAP29 Rho GTPase activating protein 29 -2.14055
ADAR adenosine deaminase, RNA-specific -2.1346
SPINT1 serine peptidase inhibitor, Kunitz type 1 -2.13315
EXOSC10 exosome component 10 -2.1309
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 -2.12995
GOLT1B golgi transport 1B -2.12725
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.1268
OSBPL11 oxysterol binding protein-like 11 -2.12535
SSB Sjogren syndrome antigen B (autoantigen La) -2.12525
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -2.12495
ZFAND1 zinc finger, AN1-type domain 1 -2.1219
PDZD8 PDZ domain containing 8 -2.12055
SAMD9 sterile alpha motif domain containing 9 -2.1166
PRPF3 pre-mRNA processing factor 3 -2.1116
PON2 paraoxonase 2 -2.11048
TSTD1 thiosulfate sulfurtransferase (rhodanese)-like domain containing 1 -2.10985
MUS81 MUS81 structure-specific endonuclease subunit -2.10855
MID1IP1 MID1 interacting protein 1 -2.1084
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -2.10695
FTSJ3 FtsJ homolog 3 (E. coli) -2.1042
ATP6V1G1 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1 -2.09835
ZNF354A zinc finger protein 354A -2.0948
SDCBP syndecan binding protein (syntenin) -2.0856
PMP22 peripheral myelin protein 22 -2.08429
NME7 NME/NM23 family member 7 -2.0827
PTPN14 protein tyrosine phosphatase, non-receptor type 14 -2.08185
NUDC nudC nuclear distribution protein -2.07827
PDGFC platelet derived growth factor C -2.0743
CD81 CD81 molecule -2.07235
LYPD1 LY6/PLAUR domain containing 1 -2.0627
INSIG2 insulin induced gene 2 -2.0625
TPD52-MRPS28 TPD52-MRPS28 readthrough -2.05974
COA4 cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) -2.0594
BIRC3 baculoviral IAP repeat containing 3 -2.058
CCP110 centriolar coiled coil protein 110kDa -2.05495
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -2.05007
GREM1 gremlin 1, DAN family BMP antagonist -2.0472
PTK2 protein tyrosine kinase 2 -2.046
PCID2 PCI domain containing 2 -2.0457
KHDC4 KH domain containing 4, pre-mRNA splicing factor -2.04555
TKT transketolase -2.04393
RBM34 RNA binding motif protein 34 -2.03393
VCPKMT valosin containing protein lysine (K) methyltransferase -2.03385
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.0337
ANXA1 annexin A1 -2.02535
UPP1 uridine phosphorylase 1 -2.0233
OSBPL8 oxysterol binding protein-like 8 -2.02067
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.01075
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 -2.01015
TXLNA taxilin alpha -2.00805
BBIP1 BBSome interacting protein 1 -2.00747
WAPL WAPL cohesin release factor -2.0047
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial -2.0005