CRCGN017_MCF10A.WT.HP_24H:K24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description curcumin 11.23 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

981 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:K24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
HMOX1 heme oxygenase 1 10.0
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 8.70565
LRP10 low density lipoprotein receptor-related protein 10 7.9752
GLRX glutaredoxin (thioltransferase) 6.91302
SQSTM1 sequestosome 1 6.64358
ABHD4 abhydrolase domain containing 4 6.43215
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 6.33705
NUCB2 nucleobindin 2 6.0535
OXSR1 oxidative stress responsive 1 5.9037
TXNRD1 thioredoxin reductase 1 5.596
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 5.56525
TBX2 T-box 2 5.41933
CTSL cathepsin L 5.36785
AGR2 anterior gradient 2 5.20365
PTPN1 protein tyrosine phosphatase, non-receptor type 1 4.8977
CLTC clathrin, heavy chain (Hc) 4.87515
ALAS1 5'-aminolevulinate synthase 1 4.75765
UBQLN2 ubiquilin 2 4.75445
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 4.73235
AARS1 alanyl-tRNA synthetase 1 4.60425
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 4.5137
DUSP14 dual specificity phosphatase 14 4.4808
TMEM50A transmembrane protein 50A 4.4543
PGRMC1 progesterone receptor membrane component 1 4.41078
DUSP4 dual specificity phosphatase 4 4.39485
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 4.32428
GFPT1 glutamine--fructose-6-phosphate transaminase 1 4.29462
SLC35B1 solute carrier family 35, member B1 4.2545
GATA3 GATA binding protein 3 4.21972
CHPF2 chondroitin polymerizing factor 2 4.17207
SCRN1 secernin 1 4.1238
HBA1 hemoglobin, alpha 1 4.1131
TM9SF3 transmembrane 9 superfamily member 3 4.1094
ABHD6 abhydrolase domain containing 6 4.00303
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 3.96497
PLA2G15 phospholipase A2, group XV 3.90845
FHL2 four and a half LIM domains 2 3.89405
LSR lipolysis stimulated lipoprotein receptor 3.82555
RBKS ribokinase 3.8154
RGS2 regulator of G-protein signaling 2 3.7757
CANT1 calcium activated nucleotidase 1 3.7636
MCUR1 mitochondrial calcium uniporter regulator 1 3.73955
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 3.71817
UBE2A ubiquitin-conjugating enzyme E2A 3.67797
TALDO1 transaldolase 1 3.6699
WFS1 Wolfram syndrome 1 (wolframin) 3.6251
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 3.61325
WIPI1 WD repeat domain, phosphoinositide interacting 1 3.59138
GARS1 glycyl-tRNA synthetase 1 3.58775
TICAM1 toll-like receptor adaptor molecule 1 3.58065
FOXO4 forkhead box O4 3.56435
GABARAPL1 GABA(A) receptor-associated protein like 1 3.5229
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.49855
KEAP1 kelch-like ECH-associated protein 1 3.4954
TM9SF2 transmembrane 9 superfamily member 2 3.4777
IST1 increased sodium tolerance 1 homolog (yeast) 3.458
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.456
TERF2IP telomeric repeat binding factor 2, interacting protein 3.4368
MVP major vault protein 3.39405
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.3508
PKN1 protein kinase N1 3.32778
HBB hemoglobin, beta 3.3123
GCLM glutamate-cysteine ligase, modifier subunit 3.30425
SLC35F6 solute carrier family 35, member F6 3.30085
PSEN2 presenilin 2 3.3006
TNIP1 TNFAIP3 interacting protein 1 3.2906
MAPK13 mitogen-activated protein kinase 13 3.27292
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 3.23795
VGLL4 vestigial-like family member 4 3.21578
CTSA cathepsin A 3.21465
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 3.20645
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.2042
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa 3.19817
CCND3 cyclin D3 3.192
COPB1 coatomer protein complex, subunit beta 1 3.19132
STXBP1 syntaxin binding protein 1 3.1547
RAB11FIP5 RAB11 family interacting protein 5 (class I) 3.13695
SEC24A SEC24 family member A 3.13657
CNPY4 canopy FGF signaling regulator 4 3.1274
LRRC8E leucine rich repeat containing 8 family, member E 3.1234
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 3.0995
FOXD1 forkhead box D1 3.0844
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 3.07697
MSX2 msh homeobox 2 3.0754
PERP PERP, TP53 apoptosis effector 3.07485
TMCO1 transmembrane and coiled-coil domains 1 3.07203
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.06422
ITPKC inositol-trisphosphate 3-kinase C 3.05855
ACAA1 acetyl-CoA acyltransferase 1 3.05512
KIF13B kinesin family member 13B 3.0516
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 3.04827
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11 3.0368
AVPI1 arginine vasopressin-induced 1 3.03545
NPY5R neuropeptide Y receptor Y5 3.0349
ARMCX3 armadillo repeat containing, X-linked 3 3.02605
RAP1GAP RAP1 GTPase activating protein 3.02275
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 3.00775
SQOR sulfide quinone oxidoreductase 3.0068
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 2.9974
OSGIN1 oxidative stress induced growth inhibitor 1 2.99165
SMIM10L1 small integral membrane protein 10 like 1 2.98755
CARS1 cysteinyl-tRNA synthetase 1 2.977
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.97697
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 2.9701
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 2.96525
PCBP3 poly(rC) binding protein 3 2.96375
LGALS8 lectin, galactoside-binding, soluble, 8 2.95772
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1 2.95765
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 2.95658
CDPF1 cysteine-rich, DPF motif domain containing 1 2.944
MAP2K3 mitogen-activated protein kinase kinase 3 2.93265
TMEM41B transmembrane protein 41B 2.91883
SCAF8 SR-related CTD-associated factor 8 2.91365
LPAR1 lysophosphatidic acid receptor 1 2.91058
GPR137B G protein-coupled receptor 137B 2.9048
VSIG2 V-set and immunoglobulin domain containing 2 2.90185
SEPHS2 selenophosphate synthetase 2 2.899
RABAC1 Rab acceptor 1 (prenylated) 2.89755
TMEM40 transmembrane protein 40 2.8919
LARP6 La ribonucleoprotein domain family, member 6 2.87645
MAN2B1 mannosidase, alpha, class 2B, member 1 2.87095
KIFC3 kinesin family member C3 2.86615
LOC114841035 uncharacterized LOC114841035 2.8594
BHMT2 betaine--homocysteine S-methyltransferase 2 2.8487
STC2 stanniocalcin 2 2.84742
ADGRD2 adhesion G protein-coupled receptor D2 2.8469
BCAS4 breast carcinoma amplified sequence 4 2.84325
ELOVL1 ELOVL fatty acid elongase 1 2.84288
KLHL21 kelch-like family member 21 2.835
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.81753
PI3 peptidase inhibitor 3, skin-derived 2.8125
RNLS renalase, FAD-dependent amine oxidase 2.8107
PKP1 plakophilin 1 2.8102
DDA1 DET1 and DDB1 associated 1 2.7813
KIF5C kinesin family member 5C 2.7798
TFE3 transcription factor binding to IGHM enhancer 3 2.77577
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 2.77405
MAP7 microtubule-associated protein 7 2.76235
TUFT1 tuftelin 1 2.7555
HSPB8 heat shock 22kDa protein 8 2.74765
LMTK1 lemur tail kinase 1 2.73695
LOC128125814 uncharacterized LOC128125814 2.73105
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.72395
RABEP2 rabaptin, RAB GTPase binding effector protein 2 2.7222
BDKRB2 bradykinin receptor B2 2.721
RNF103 ring finger protein 103 2.7204
APOL2 apolipoprotein L, 2 2.71863
NPC1 Niemann-Pick disease, type C1 2.71598
BAG3 BCL2-associated athanogene 3 2.70965
GBA1 glucosylceramidase beta 1 2.70073
NDEL1 nudE neurodevelopment protein 1-like 1 2.69885
SAA2 serum amyloid A2 2.69318
PRR13 proline rich 13 2.6901
TMEM59 transmembrane protein 59 2.68985
QSOX1 quiescin Q6 sulfhydryl oxidase 1 2.6843
UBTD1 ubiquitin domain containing 1 2.6802
IER3 immediate early response 3 2.67995
PTTG1IP pituitary tumor-transforming 1 interacting protein 2.6698
H2AC19 H2A clustered histone 19 2.66482
GARRE1 granule associated Rac and RHOG effector 1 2.6585
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 2.65455
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.6532
PGPEP1 pyroglutamyl-peptidase I 2.65235
FYN FYN proto-oncogene, Src family tyrosine kinase 2.64833
TM4SF1 transmembrane 4 L six family member 1 2.64593
NUP58 nucleoporin 58 2.63285
SIL1 SIL1 nucleotide exchange factor 2.63045
PRSS8 protease, serine, 8 2.6292
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 2.62745
LYPD3 LY6/PLAUR domain containing 3 2.61855
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 2.61825
YPEL5 yippee-like 5 (Drosophila) 2.618
RRAGA Ras-related GTP binding A 2.61785
IL36RN interleukin 36 receptor antagonist 2.61755
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.614
LAD1 ladinin 1 2.60025
RNF10 ring finger protein 10 2.59955
EBI3 Epstein-Barr virus induced 3 2.59335
RHOG ras homolog family member G 2.5923
AMOTL2 angiomotin like 2 2.5854
TXNDC15 thioredoxin domain containing 15 2.5777
CRCT1 cysteine-rich C-terminal 1 2.57725
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.57175
VEGFC vascular endothelial growth factor C 2.5698
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 2.56845
SOD1 superoxide dismutase 1, soluble 2.56315
TP53BP2 tumor protein p53 binding protein 2 2.5595
TWF2 twinfilin actin binding protein 2 2.5594
SH2D2A SH2 domain containing 2A 2.55885
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 2.5581
AAMDC adipogenesis associated, Mth938 domain containing 2.55778
ISG20 interferon stimulated exonuclease gene 20kDa 2.55667
SAMD9 sterile alpha motif domain containing 9 2.54295
PRSS22 protease, serine, 22 2.5363
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.5303
FKBP11 FK506 binding protein 11, 19 kDa 2.52968
PTPN20 protein tyrosine phosphatase, non-receptor type 20 2.5292
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 2.51142
TM4SF20 transmembrane 4 L six family member 20 2.5103
FSTL1 follistatin-like 1 2.50405
LMO7 LIM domain 7 2.49875
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 2.4978
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 2.49615
CYB5R1 cytochrome b5 reductase 1 2.49385
UPP1 uridine phosphorylase 1 2.49355
CNKSR1 connector enhancer of kinase suppressor of Ras 1 2.49315
WIPI2 WD repeat domain, phosphoinositide interacting 2 2.48658
ELOVL4 ELOVL fatty acid elongase 4 2.48215
STX4 syntaxin 4 2.4782
CLDN5 claudin 5 2.47655
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.47445
G0S2 G0/G1 switch 2 2.4683
RASAL2 RAS protein activator like 2 2.4634
AKR1C1 aldo-keto reductase family 1, member C1 2.45941
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 2.45795
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.45535
KRT1 keratin 1, type II 2.45455
ROM1 retinal outer segment membrane protein 1 2.45025
BLVRB biliverdin reductase B 2.4477
ZFP36 ZFP36 ring finger protein 2.446
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 2.4436
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.43615
ATG13 autophagy related 13 2.4349
BSDC1 BSD domain containing 1 2.42295
GCC1 GRIP and coiled-coil domain containing 1 2.4228
HDLBP high density lipoprotein binding protein 2.42182
BEST1 bestrophin 1 2.4205
TMEM140 transmembrane protein 140 2.41945
CEMIP2 cell migration inducing hyaluronidase 2 2.4138
CTC1 CTS telomere maintenance complex component 1 2.41245
UGDH UDP-glucose 6-dehydrogenase 2.40855
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 2.40685
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 2.40595
GNAS GNAS complex locus 2.40478
PLK3 polo-like kinase 3 2.4005
IGFBP6 insulin-like growth factor binding protein 6 2.39535
EEIG1 estrogen-induced osteoclastogenesis regulator 1 2.39515
CDSN corneodesmosin 2.391
CCPG1 cell cycle progression 1 2.38559
FXR2 fragile X mental retardation, autosomal homolog 2 2.3842
NIT1 nitrilase 1 2.38045
SPATA2L spermatogenesis associated 2-like 2.38025
OLAH oleoyl-ACP hydrolase 2.37995
CALCB calcitonin-related polypeptide beta 2.37105
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.3697
LAMB3 laminin, beta 3 2.3697
RGS3 regulator of G-protein signaling 3 2.36825
USP9X ubiquitin specific peptidase 9, X-linked 2.36678
CSRP1 cysteine and glycine-rich protein 1 2.36323
KPNA4 karyopherin alpha 4 (importin alpha 3) 2.3598
GPC1 glypican 1 2.35822
RNF220 ring finger protein 220 2.35375
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit 2.35148
RNF11 ring finger protein 11 2.35075
PPP4R1 protein phosphatase 4, regulatory subunit 1 2.3488
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 2.3483
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 2.3479
LPGAT1 lysophosphatidylglycerol acyltransferase 1 2.34485
MAGED1 melanoma antigen family D1 2.3444
GORASP2 golgi reassembly stacking protein 2, 55kDa 2.3443
TIMP2 TIMP metallopeptidase inhibitor 2 2.34275
NFE2L1 nuclear factor, erythroid 2-like 1 2.34078
CGB8 chorionic gonadotropin, beta polypeptide 8 2.33605
PHGDH phosphoglycerate dehydrogenase 2.3334
EMC3 ER membrane protein complex subunit 3 2.3311
ELF4 E74-like factor 4 (ets domain transcription factor) 2.32553
TRIM62 tripartite motif containing 62 2.32442
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide 2.3162
CERS2 ceramide synthase 2 2.3156
C2CD2 C2 calcium-dependent domain containing 2 2.31335
LRRC41 leucine rich repeat containing 41 2.3092
LRRC32 leucine rich repeat containing 32 2.30875
MAST4 microtubule associated serine/threonine kinase family member 4 2.3058
PLS3 plastin 3 2.30325
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 2.29925
IL36G interleukin 36, gamma 2.29565
ALX1 ALX homeobox 1 2.2927
GTPBP2 GTP binding protein 2 2.28365
ULBP2 UL16 binding protein 2 2.283
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 2.2801
USP47 ubiquitin specific peptidase 47 2.27922
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 2.2769
SP140 SP140 nuclear body protein 2.27655
MAP1B microtubule-associated protein 1B 2.27408
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.2734
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 2.2726
MISP mitotic spindle positioning 2.2706
OSBPL2 oxysterol binding protein-like 2 2.26165
CXCL2 chemokine (C-X-C motif) ligand 2 2.26065
ATOSB atos homolog B 2.25883
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 2.25423
PDK2 pyruvate dehydrogenase kinase, isozyme 2 2.24972
KLC3 kinesin light chain 3 2.24645
KRT6B keratin 6B, type II 2.24485
LYPLA2 lysophospholipase II 2.24437
TBC1D13 TBC1 domain family, member 13 2.23955
EFNA1 ephrin-A1 2.23855
TSG101 tumor susceptibility 101 2.237
CHIC2 cysteine-rich hydrophobic domain 2 2.23635
ZDHHC18 zinc finger, DHHC-type containing 18 2.2354
CCDC92 coiled-coil domain containing 92 2.23395
CD5L CD5 molecule-like 2.23265
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 2.23172
SUCO SUN domain containing ossification factor 2.23165
HGD homogentisate 1,2-dioxygenase 2.23067
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 2.2289
USH1C Usher syndrome 1C (autosomal recessive, severe) 2.22793
NABP1 nucleic acid binding protein 1 2.2268
CBR1 carbonyl reductase 1 2.22655
AHCYL2 adenosylhomocysteinase-like 2 2.22447
DACH1 dachshund family transcription factor 1 2.22337
FBN2 fibrillin 2 2.22073
SLC6A14 solute carrier family 6 (amino acid transporter), member 14 2.2168
TMBIM1 transmembrane BAX inhibitor motif containing 1 2.21635
MBD5 methyl-CpG binding domain protein 5 2.2159
SEC62 SEC62 homolog (S. cerevisiae) 2.21578
AKIRIN1 akirin 1 2.21415
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 2.21325
AOC1 amine oxidase, copper containing 1 2.2088
TRIM16 tripartite motif containing 16 2.20775
GLB1 galactosidase, beta 1 2.20705
CRYGB crystallin, gamma B 2.2062
CDC34 cell division cycle 34 2.20605
PDZK1IP1 PDZK1 interacting protein 1 2.204
HYAL4 hyaluronoglucosaminidase 4 2.20365
MID1IP1 MID1 interacting protein 1 2.20185
TMCC2 transmembrane and coiled-coil domain family 2 2.1991
DAPK3 death-associated protein kinase 3 2.19895
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 2.197
REXO2 RNA exonuclease 2 2.19629
CBR3 carbonyl reductase 3 2.194
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.19095
ELL2 elongation factor, RNA polymerase II, 2 2.1907
STC1 stanniocalcin 1 2.18867
SFRP5 secreted frizzled-related protein 5 2.18765
CCN2 cellular communication network factor 2 2.1857
OCLN occludin 2.18515
CLDN4 claudin 4 2.17785
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.17765
IL21R interleukin 21 receptor 2.17737
GPRC5A G protein-coupled receptor, class C, group 5, member A 2.1772
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 2.17515
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.1734
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b 2.1732
LBP lipopolysaccharide binding protein 2.17282
MMP25 matrix metallopeptidase 25 2.17085
IER2 immediate early response 2 2.1708
PCDH1 protocadherin 1 2.1693
DMTF1 cyclin D binding myb-like transcription factor 1 2.16547
NXPE3 neurexophilin and PC-esterase domain family, member 3 2.1654
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 2.16465
SKIC2 SKI2 subunit of superkiller complex 2.1612
INPPL1 inositol polyphosphate phosphatase-like 1 2.1593
KRT34 keratin 34, type I 2.15725
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 2.15462
IFRD1 interferon-related developmental regulator 1 2.15433
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 2.1513
ARMCX2 armadillo repeat containing, X-linked 2 2.1498
P3H1 prolyl 3-hydroxylase 1 2.14945
LXN latexin 2.1494
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated 2.14925
KRT16 keratin 16, type I 2.14565
ITSN2 intersectin 2 2.14325
PCSK7 proprotein convertase subtilisin/kexin type 7 2.1425
TMEM127 transmembrane protein 127 2.14125
CLCN4 chloride channel, voltage-sensitive 4 2.14096
RNF114 ring finger protein 114 2.14067
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 2.1379
TFF1 trefoil factor 1 2.136
STK10 serine/threonine kinase 10 2.1359
PINK1 PTEN induced putative kinase 1 2.13477
PLEKHA5 pleckstrin homology domain containing, family A member 5 2.1346
AKR1C3 aldo-keto reductase family 1, member C3 2.13405
TJP1 tight junction protein 1 2.13325
TPST2 tyrosylprotein sulfotransferase 2 2.1314
RHOF ras homolog family member F (in filopodia) 2.1302
UBE2H ubiquitin-conjugating enzyme E2H 2.12738
SLC16A4 solute carrier family 16, member 4 2.1253
BORCS8 BLOC-1 related complex subunit 8 2.12245
FXYD5 FXYD domain containing ion transport regulator 5 2.12065
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 2.11785
NID2 nidogen 2 (osteonidogen) 2.11735
PHTF1 putative homeodomain transcription factor 1 2.1172
CSNK1E casein kinase 1, epsilon 2.11632
TSPAN1 tetraspanin 1 2.1129
GMIP GEM interacting protein 2.11165
ADAP2 ArfGAP with dual PH domains 2 2.1114
RUBCN rubicon autophagy regulator 2.11075
HPGDS hematopoietic prostaglandin D synthase 2.10855
LMX1B LIM homeobox transcription factor 1, beta 2.10765
WDR44 WD repeat domain 44 2.10465
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 2.10255
TIMP4 TIMP metallopeptidase inhibitor 4 2.1024
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 2.0994
POPDC3 popeye domain containing 3 2.09915
FAM110D family with sequence similarity 110, member D 2.09825
TMEM248 transmembrane protein 248 2.09695
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 2.09355
RPN1 ribophorin I 2.09095
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.09015
GNG11 guanine nucleotide binding protein (G protein), gamma 11 2.0889
CASZ1 castor zinc finger 1 2.08545
BDKRB1 bradykinin receptor B1 2.08475
P3H3 prolyl 3-hydroxylase 3 2.08445
DHRS7 dehydrogenase/reductase (SDR family) member 7 2.0821
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 2.08085
ATP9A ATPase, class II, type 9A 2.08065
ACTN4 actinin, alpha 4 2.0789
NPPA natriuretic peptide A 2.07825
IGFBP1 insulin-like growth factor binding protein 1 2.0778
CLU clusterin 2.07767
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 2.07735
PLAAT3 phospholipase A and acyltransferase 3 2.0729
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 2.07085
SH2B3 SH2B adaptor protein 3 2.0675
FOSL1 FOS-like antigen 1 2.0665
EIF1B eukaryotic translation initiation factor 1B 2.0655
STEAP1B STEAP family member 1B 2.06095
CACFD1 calcium channel flower domain containing 1 2.058
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 2.05765
ELAVL3 ELAV like neuron-specific RNA binding protein 3 2.05725
DSPP dentin sialophosphoprotein 2.05452
ITPRID2 ITPR interacting domain containing 2 2.05375
INO80B INO80 complex subunit B 2.05325
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F 2.0531
MYL10 myosin, light chain 10, regulatory 2.05078
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 2.04945
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 2.04685
ENDOD1 endonuclease domain containing 1 2.04502
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 2.04465
SSR4 signal sequence receptor, delta 2.04245
F2RL1 coagulation factor II (thrombin) receptor-like 1 2.03902
DOLK dolichol kinase 2.0377
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.03735
GGTLC1 gamma-glutamyltransferase light chain 1 2.037
ATG2A autophagy related 2A 2.03685
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 2.03638
STXBP2 syntaxin binding protein 2 2.03615
TBX4 T-box 4 2.03375
POF1B premature ovarian failure, 1B 2.0319
RNMT RNA (guanine-7-) methyltransferase 2.03117
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 2.0303
NRBF2 nuclear receptor binding factor 2 2.03025
GIPC1 GIPC PDZ domain containing family, member 1 2.02765
IL32 interleukin 32 2.02635
BRMS1L breast cancer metastasis-suppressor 1-like 2.02615
ATF3 activating transcription factor 3 2.02555
CCDC30 coiled-coil domain containing 30 2.02075
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma 2.01825
FNDC4 fibronectin type III domain containing 4 2.01585
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 2.01425
YIPF1 Yip1 domain family, member 1 2.0133
AFF4 AF4/FMR2 family, member 4 2.01305
TUBAL3 tubulin, alpha-like 3 2.01115
LIN7A lin-7 homolog A (C. elegans) 2.01065
ELMO2 engulfment and cell motility 2 2.01
RRAGC Ras-related GTP binding C 2.0095
SEC24B SEC24 family member B 2.00935
TPST1 tyrosylprotein sulfotransferase 1 2.00595
EPHA2 EPH receptor A2 2.00565
CTAGE8 CTAGE family, member 8 2.00425
LOC124906748 beta-defensin 4A 2.003
CYTH2 cytohesin 2 2.00295
UBA1 ubiquitin-like modifier activating enzyme 1 2.00285

decreased expression

Symbol Name Standardized Value
HADH hydroxyacyl-CoA dehydrogenase -8.03522
PSRC1 proline/serine-rich coiled-coil 1 -7.4459
TRAP1 TNF receptor-associated protein 1 -7.0497
TOP2A topoisomerase (DNA) II alpha 170kDa -7.03935
PARP2 poly (ADP-ribose) polymerase 2 -6.69435
CDC45 cell division cycle 45 -6.4475
MSMO1 methylsterol monooxygenase 1 -6.3966
PCNA proliferating cell nuclear antigen -6.2777
ISOC1 isochorismatase domain containing 1 -6.2638
UBE2C ubiquitin-conjugating enzyme E2C -6.18685
CCNB2 cyclin B2 -5.66715
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -5.66475
STMN1 stathmin 1 -5.6134
CDK1 cyclin-dependent kinase 1 -5.52677
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -5.22535
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -5.1191
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 -5.07225
CDK4 cyclin-dependent kinase 4 -5.0333
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -4.96385
CYCS cytochrome c, somatic -4.823
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.7628
CDC20 cell division cycle 20 -4.7268
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.7007
CRYZ crystallin, zeta (quinone reductase) -4.6495
ANKRD10 ankyrin repeat domain 10 -4.639
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.57945
GPHN gephyrin -4.5283
NLRP4 NLR family, pyrin domain containing 4 -4.523
NUP85 nucleoporin 85kDa -4.4577
NUP93 nucleoporin 93kDa -4.41725
HSPD1 heat shock 60kDa protein 1 (chaperonin) -4.30367
NUSAP1 nucleolar and spindle associated protein 1 -4.29682
DNM1 dynamin 1 -4.2743
NT5DC2 5'-nucleotidase domain containing 2 -4.2224
RUVBL1 RuvB-like AAA ATPase 1 -4.06655
ACYP1 acylphosphatase 1, erythrocyte (common) type -4.03565
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -3.96855
PYGL phosphorylase, glycogen, liver -3.96695
BIRC5 baculoviral IAP repeat containing 5 -3.9468
ZDHHC6 zinc finger, DHHC-type containing 6 -3.94015
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) -3.92015
ZNF692 zinc finger protein 692 -3.90495
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -3.89545
HSPA8 heat shock 70kDa protein 8 -3.88463
CCNA2 cyclin A2 -3.88068
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -3.86765
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.84257
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -3.80165
CETN3 centrin, EF-hand protein, 3 -3.7055
EBNA1BP2 EBNA1 binding protein 2 -3.70065
NUP37 nucleoporin 37kDa -3.6996
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.65637
METTL17 methyltransferase like 17 -3.6475
BID BH3 interacting domain death agonist -3.64548
ELP4 elongator acetyltransferase complex subunit 4 -3.62565
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -3.6099
SDHAF3 succinate dehydrogenase complex assembly factor 3 -3.60865
SCARB1 scavenger receptor class B, member 1 -3.58333
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.5708
MRPS17 mitochondrial ribosomal protein S17 -3.56795
SH3D19 SH3 domain containing 19 -3.55242
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -3.54285
COMMD10 COMM domain containing 10 -3.536
AURKB aurora kinase B -3.52755
RPL39L ribosomal protein L39-like -3.5251
FAF1 Fas (TNFRSF6) associated factor 1 -3.5199
NUP42 nucleoporin 42 -3.51005
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -3.5086
EIF3D eukaryotic translation initiation factor 3, subunit D -3.49705
TROAP trophinin associated protein -3.4913
STOML2 stomatin (EPB72)-like 2 -3.49065
TCTN1 tectonic family member 1 -3.46825
PLK1 polo-like kinase 1 -3.45535
DCK deoxycytidine kinase -3.4375
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.4271
RACGAP1 Rac GTPase activating protein 1 -3.42105
EVL Enah/Vasp-like -3.40465
DSCC1 DNA replication and sister chromatid cohesion 1 -3.4007
KAT2A K(lysine) acetyltransferase 2A -3.39405
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae) -3.3664
OSGEP O-sialoglycoprotein endopeptidase -3.3618
OIP5 Opa interacting protein 5 -3.354
BZW2 basic leucine zipper and W2 domains 2 -3.33095
TRIP13 thyroid hormone receptor interactor 13 -3.31185
CENPA centromere protein A -3.3004
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.2979
GINS2 GINS complex subunit 2 (Psf2 homolog) -3.29455
KIF15 kinesin family member 15 -3.2943
FKBP5 FK506 binding protein 5 -3.2855
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -3.27413
TP53 tumor protein p53 -3.27275
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.26895
PARPBP PARP1 binding protein -3.26765
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -3.26745
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 -3.26695
S100A13 S100 calcium binding protein A13 -3.26547
PBK PDZ binding kinase -3.264
EIF3E eukaryotic translation initiation factor 3, subunit E -3.25385
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -3.2496
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -3.24015
REV1 REV1, polymerase (DNA directed) -3.2297
KIF20A kinesin family member 20A -3.22415
MDH1 malate dehydrogenase 1, NAD (soluble) -3.2223
NCAPH non-SMC condensin I complex, subunit H -3.20765
PEX2 peroxisomal biogenesis factor 2 -3.20405
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 -3.20015
CDCA4 cell division cycle associated 4 -3.19845
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase -3.19735
OXA1L oxidase (cytochrome c) assembly 1-like -3.1963
MRPL11 mitochondrial ribosomal protein L11 -3.19495
NCAPD2 non-SMC condensin I complex, subunit D2 -3.17925
FANCI Fanconi anemia, complementation group I -3.1768
SESN1 sestrin 1 -3.1766
MTRF1 mitochondrial translational release factor 1 -3.1725
POLD1 polymerase (DNA directed), delta 1, catalytic subunit -3.15695
NUP107 nucleoporin 107kDa -3.14125
ADSL adenylosuccinate lyase -3.13613
OXCT1 3-oxoacid CoA transferase 1 -3.11985
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa -3.11948
C1QBP complement component 1, q subcomponent binding protein -3.11345
ASF1B anti-silencing function 1B histone chaperone -3.11105
COQ6 coenzyme Q6 monooxygenase -3.1087
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -3.1071
MAT2B methionine adenosyltransferase II, beta -3.0882
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 -3.08535
RFC3 replication factor C (activator 1) 3, 38kDa -3.08195
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.07315
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.06695
ATAD2 ATPase family, AAA domain containing 2 -3.06325
TSEN2 TSEN2 tRNA splicing endonuclease subunit -3.05515
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) -3.0539
ZFAND1 zinc finger, AN1-type domain 1 -3.0467
DPYD dihydropyrimidine dehydrogenase -3.0458
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -3.0439
GEMIN2 gem (nuclear organelle) associated protein 2 -3.03539
RPIA ribose 5-phosphate isomerase A -3.03065
NCKIPSD NCK interacting protein with SH3 domain -3.0257
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -3.02438
SPC25 SPC25, NDC80 kinetochore complex component -3.02135
MIS18A MIS18 kinetochore protein A -3.0182
YEATS4 YEATS domain containing 4 -2.98965
S100A4 S100 calcium binding protein A4 -2.98825
GEMIN6 gem (nuclear organelle) associated protein 6 -2.98155
SCML1 sex comb on midleg-like 1 (Drosophila) -2.96325
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -2.95915
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -2.9495
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -2.94315
THYN1 thymocyte nuclear protein 1 -2.9429
NPM3 nucleophosmin/nucleoplasmin 3 -2.9407
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.9286
ATP5PB ATP synthase peripheral stalk-membrane subunit b -2.9218
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.91575
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -2.90963
CBX3 chromobox homolog 3 -2.9071
GFUS GDP-L-fucose synthase -2.90147
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.89965
ZNF83 zinc finger protein 83 -2.89905
ABHD10 abhydrolase domain containing 10 -2.8858
NCAPG2 non-SMC condensin II complex, subunit G2 -2.88235
KNTC1 kinetochore associated 1 -2.87765
KHDC4 KH domain containing 4, pre-mRNA splicing factor -2.8711
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -2.8549
CCNF cyclin F -2.85098
CDCA8 cell division cycle associated 8 -2.85005
THOC6 THO complex 6 -2.84525
IFRD2 interferon-related developmental regulator 2 -2.84072
NFIL3 nuclear factor, interleukin 3 regulated -2.8363
IPO4 importin 4 -2.82775
ERAP2 endoplasmic reticulum aminopeptidase 2 -2.8265
DSN1 DSN1, MIS12 kinetochore complex component -2.8216
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B -2.81925
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -2.8191
MRPL42 mitochondrial ribosomal protein L42 -2.8184
KIF18B kinesin family member 18B -2.8158
MPHOSPH9 M-phase phosphoprotein 9 -2.81475
CRIP2 cysteine-rich protein 2 -2.8047
FXN frataxin -2.7909
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.7806
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.768
EXO1 exonuclease 1 -2.7642
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.75973
NME7 NME/NM23 family member 7 -2.74165
ALDOC aldolase C, fructose-bisphosphate -2.73455
RBMX RNA binding motif protein, X-linked -2.72685
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.71615
DDB2 damage-specific DNA binding protein 2, 48kDa -2.716
RBL2 retinoblastoma-like 2 -2.71448
EXOSC8 exosome component 8 -2.7137
SMYD2 SET and MYND domain containing 2 -2.7119
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.71125
NEK2 NIMA-related kinase 2 -2.70268
CKAP2 cytoskeleton associated protein 2 -2.6987
INTS8 integrator complex subunit 8 -2.69085
VRK1 vaccinia related kinase 1 -2.67915
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -2.67725
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 -2.67718
QTRT1 queuine tRNA-ribosyltransferase 1 -2.675
CDC7 cell division cycle 7 -2.66975
CA9 carbonic anhydrase IX -2.6672
SIRAL2 SIR2 antiphage like 2 -2.66375
MRPL35 mitochondrial ribosomal protein L35 -2.66165
MKKS McKusick-Kaufman syndrome -2.661
KIF11 kinesin family member 11 -2.6374
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1 -2.6344
KIF14 kinesin family member 14 -2.6344
CCT2 chaperonin containing TCP1, subunit 2 (beta) -2.6336
MOCS2 molybdenum cofactor synthesis 2 -2.6333
ENC1 ectodermal-neural cortex 1 (with BTB domain) -2.63037
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.62705
FBXO5 F-box protein 5 -2.62115
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.6199
GTSE1 G-2 and S-phase expressed 1 -2.61764
MRPL39 mitochondrial ribosomal protein L39 -2.605
ITGB1BP1 integrin beta 1 binding protein 1 -2.60332
TXNRD3 thioredoxin reductase 3 -2.59877
LBR lamin B receptor -2.5925
EXOSC9 exosome component 9 -2.5923
GMNN geminin, DNA replication inhibitor -2.58393
NDC80 NDC80 kinetochore complex component -2.5826
CKS1B CDC28 protein kinase regulatory subunit 1B -2.5823
RXYLT1 ribitol xylosyltransferase 1 -2.5783
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -2.5768
HMGB1 high mobility group box 1 -2.57657
PTTG1 pituitary tumor-transforming 1 -2.5758
CBY1 chibby homolog 1 (Drosophila) -2.5715
WDR12 WD repeat domain 12 -2.5701
AK4 adenylate kinase 4 -2.56813
TUBA3E tubulin, alpha 3e -2.5664
RPRD1A regulation of nuclear pre-mRNA domain containing 1A -2.56105
CDKN3 cyclin-dependent kinase inhibitor 3 -2.55915
CABIN1 calcineurin binding protein 1 -2.55673
ZNF148 zinc finger protein 148 -2.556
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -2.55585
WASF1 WAS protein family, member 1 -2.5533
SARS2 seryl-tRNA synthetase 2, mitochondrial -2.55285
LDHD lactate dehydrogenase D -2.5497
RSRC1 arginine/serine-rich coiled-coil 1 -2.5464
DTYMK deoxythymidylate kinase (thymidylate kinase) -2.54335
RPA3 replication protein A3, 14kDa -2.5412
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 -2.5379
RYK receptor-like tyrosine kinase -2.5355
RSU1 Ras suppressor protein 1 -2.5322
SNRPA small nuclear ribonucleoprotein polypeptide A -2.5305
RSL1D1 ribosomal L1 domain containing 1 -2.52405
IGF1 insulin-like growth factor 1 (somatomedin C) -2.52085
ZWINT ZW10 interacting kinetochore protein -2.52005
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) -2.51423
RBP1 retinol binding protein 1, cellular -2.51335
CD320 CD320 molecule -2.5125
ERI2 ERI1 exoribonuclease family member 2 -2.5107
PGAM4 phosphoglycerate mutase family member 4 -2.50985
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.5048
ZNF16 zinc finger protein 16 -2.5007
RAN RAN, member RAS oncogene family -2.49825
MRPL58 mitochondrial ribosomal protein L58 -2.4934
RABL6 RAB, member RAS oncogene family-like 6 -2.4919
UCHL5 ubiquitin carboxyl-terminal hydrolase L5 -2.49175
ANKRD49 ankyrin repeat domain 49 -2.4908
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -2.48945
TSPAN4 tetraspanin 4 -2.4875
MRPS22 mitochondrial ribosomal protein S22 -2.4851
NUP155 nucleoporin 155kDa -2.48195
CDT1 chromatin licensing and DNA replication factor 1 -2.47975
EMC9 ER membrane protein complex subunit 9 -2.4748
SCML2 sex comb on midleg-like 2 (Drosophila) -2.4748
AGPS alkylglycerone phosphate synthase -2.4718
ACOD1 aconitate decarboxylase 1 -2.46935
PPID peptidylprolyl isomerase D -2.46172
METTL3 methyltransferase like 3 -2.46168
SPDL1 spindle apparatus coiled-coil protein 1 -2.45965
UQCRC2 ubiquinol-cytochrome c reductase core protein II -2.45732
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.4556
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) -2.4415
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -2.439
LRPPRC leucine-rich pentatricopeptide repeat containing -2.43862
SUMF2 sulfatase modifying factor 2 -2.436
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) -2.4317
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) -2.4302
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -2.42875
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 -2.42265
ENY2 enhancer of yellow 2 homolog (Drosophila) -2.4224
SRSF6 serine/arginine-rich splicing factor 6 -2.41665
APIP APAF1 interacting protein -2.41615
RMI1 RecQ mediated genome instability 1 -2.41025
CENPX centromere protein X -2.40965
AHCY adenosylhomocysteinase -2.4095
PSIP1 PC4 and SFRS1 interacting protein 1 -2.4083
GTF2A2 general transcription factor IIA, 2, 12kDa -2.40655
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.40155
SOAT2 sterol O-acyltransferase 2 -2.39945
PPA2 pyrophosphatase (inorganic) 2 -2.39345
TSC22D3 TSC22 domain family, member 3 -2.39033
ZNF124 zinc finger protein 124 -2.3897
FAM216A family with sequence similarity 216, member A -2.3872
HOXA5 homeobox A5 -2.38615
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.38485
GOLGA8A golgin A8 family, member A -2.381
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 -2.3809
ATP5F1A ATP synthase F1 subunit alpha -2.3806
MTIF2 mitochondrial translational initiation factor 2 -2.3777
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) -2.3742
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -2.37305
PRPF4 pre-mRNA processing factor 4 -2.37175
LIPT1 lipoyltransferase 1 -2.36945
CENPS-CORT CENPS-CORT readthrough -2.36925
CERS1 ceramide synthase 1 -2.36825
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.3679
PTMA prothymosin, alpha -2.36628
ACTL6A actin-like 6A -2.36055
NIPSNAP2 nipsnap homolog 2 -2.358
CPOX coproporphyrinogen oxidase -2.3556
HMGN2 high mobility group nucleosomal binding domain 2 -2.3524
ARB2A ARB2 cotranscriptional regulator A -2.3486
CDH10 cadherin 10, type 2 (T2-cadherin) -2.3486
NOP14 NOP14 nucleolar protein -2.3451
CAND1 cullin-associated and neddylation-dissociated 1 -2.3441
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.3435
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -2.3435
HIRIP3 HIRA interacting protein 3 -2.34215
DLK1 delta-like 1 homolog (Drosophila) -2.34105
TCFL5 transcription factor-like 5 (basic helix-loop-helix) -2.341
POT1 protection of telomeres 1 -2.34065
COG2 component of oligomeric golgi complex 2 -2.33945
PDCD6 programmed cell death 6 -2.3394
CUL9 cullin 9 -2.3393
USP1 ubiquitin specific peptidase 1 -2.33905
CENPM centromere protein M -2.33685
PIMREG PICALM interacting mitotic regulator -2.3356
CENPE centromere protein E, 312kDa -2.33445
MCM6 minichromosome maintenance complex component 6 -2.334
STAT5B signal transducer and activator of transcription 5B -2.33332
SNU13 small nuclear ribonucleoprotein 13 -2.32965
RFC4 replication factor C (activator 1) 4, 37kDa -2.32795
SRSF7 serine/arginine-rich splicing factor 7 -2.3273
VTI1B vesicle transport through interaction with t-SNAREs 1B -2.32305
DUT deoxyuridine triphosphatase -2.32113
TTC27 tetratricopeptide repeat domain 27 -2.32025
ICE1 interactor of little elongation complex ELL subunit 1 -2.3193
ZNF862 zinc finger protein 862 -2.31265
SAE1 SUMO1 activating enzyme subunit 1 -2.3104
CCT4 chaperonin containing TCP1, subunit 4 (delta) -2.3104
OXSM 3-oxoacyl-ACP synthase, mitochondrial -2.30555
HOXA4 homeobox A4 -2.3052
FBL fibrillarin -2.3047
POGLUT1 protein O-glucosyltransferase 1 -2.30405
TFDP1 transcription factor Dp-1 -2.30183
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.2998
WDR70 WD repeat domain 70 -2.29005
TIPRL TOR signaling pathway regulator -2.2893
PA2G4 proliferation-associated 2G4, 38kDa -2.28737
TRAPPC2L trafficking protein particle complex 2-like -2.2802
COASY CoA synthase -2.28008
ZSCAN9 zinc finger and SCAN domain containing 9 -2.27935
LSM12 LSM12 homolog (S. cerevisiae) -2.2788
MRNIP MRN complex interacting protein -2.27615
UXT ubiquitously-expressed, prefoldin-like chaperone -2.27457
TMEM14A transmembrane protein 14A -2.27265
SIVA1 SIVA1, apoptosis-inducing factor -2.2699
USP39 ubiquitin specific peptidase 39 -2.2691
CHKA choline kinase alpha -2.26342
SKIC8 SKI8 subunit of superkiller complex -2.2609
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.2606
ZXDC ZXD family zinc finger C -2.26005
KRTAP5-2 keratin associated protein 5-2 -2.2594
TBP TATA box binding protein -2.25735
TRMT5 tRNA methyltransferase 5 -2.25715
TMA16 translation machinery associated 16 homolog (S. cerevisiae) -2.252
GTPBP8 GTP-binding protein 8 (putative) -2.25025
NOP16 NOP16 nucleolar protein -2.24817
PRKD3 protein kinase D3 -2.2461
ISOC2 isochorismatase domain containing 2 -2.24455
BANF1 barrier to autointegration factor 1 -2.2436
NBPF10 neuroblastoma breakpoint family, member 10 -2.2426
CHEK1 checkpoint kinase 1 -2.2418
TSPAN6 tetraspanin 6 -2.2352
HDHD5 haloacid dehalogenase like hydrolase domain containing 5 -2.23505
IL17RB interleukin 17 receptor B -2.235
POLR1E polymerase (RNA) I polypeptide E, 53kDa -2.2338
COQ3 coenzyme Q3 methyltransferase -2.2303
EAPP E2F-associated phosphoprotein -2.23005
IMPACT impact RWD domain protein -2.22755
RFC5 replication factor C (activator 1) 5, 36.5kDa -2.22555
MPHOSPH6 M-phase phosphoprotein 6 -2.2226
NTHL1 nth endonuclease III-like 1 (E. coli) -2.22205
CS citrate synthase -2.22145
B4GAT1 beta-1,4-glucuronyltransferase 1 -2.2213
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -2.21962
TRIB2 tribbles pseudokinase 2 -2.21777
TMEM186 transmembrane protein 186 -2.2172
SLC35A5 solute carrier family 35, member A5 -2.213
ASTE1 asteroid homolog 1 (Drosophila) -2.2099
RAB20 RAB20, member RAS oncogene family -2.2094
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.2088
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.20585
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 -2.20485
NDC1 NDC1 transmembrane nucleoporin -2.20315
HMGB2 high mobility group box 2 -2.20215
MCM3 minichromosome maintenance complex component 3 -2.20195
DDIT4 DNA-damage-inducible transcript 4 -2.2001
TMEM39B transmembrane protein 39B -2.19825
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa -2.19775
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.19415
FTO fat mass and obesity associated -2.1926
FGFR3 fibroblast growth factor receptor 3 -2.19042
C2CD5 C2 calcium-dependent domain containing 5 -2.1904
DEAF1 DEAF1 transcription factor -2.18885
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.1888
DEPDC1 DEP domain containing 1 -2.18735
PRKDC protein kinase, DNA-activated, catalytic polypeptide -2.18722
ASCC3 activating signal cointegrator 1 complex subunit 3 -2.1818
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.18008
NKAPD1 NKAP domain containing 1 -2.1728
AURKA aurora kinase A -2.16965
SEPTIN7 septin 7 -2.16827
TEX30 testis expressed 30 -2.1672
MRPS16 mitochondrial ribosomal protein S16 -2.1666
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.16655
CEP83 centrosomal protein 83kDa -2.1642
CDCA3 cell division cycle associated 3 -2.16045
RPL26L1 ribosomal protein L26-like 1 -2.16015
GMPR2 guanosine monophosphate reductase 2 -2.15975
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.15967
GPS1 G protein pathway suppressor 1 -2.1585
SNRPE small nuclear ribonucleoprotein polypeptide E -2.1584
KIF4A kinesin family member 4A -2.15805
NOLC1 nucleolar and coiled-body phosphoprotein 1 -2.15422
STIL SCL/TAL1 interrupting locus -2.15055
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -2.14805
DLAT dihydrolipoamide S-acetyltransferase -2.14742
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.14485
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) -2.14442
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.1432
GINS3 GINS complex subunit 3 (Psf3 homolog) -2.14062
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) -2.1398
MCM4 minichromosome maintenance complex component 4 -2.13702
SNRPB2 small nuclear ribonucleoprotein polypeptide B -2.13535
SKA1 spindle and kinetochore associated complex subunit 1 -2.13345
TMEM126B transmembrane protein 126B -2.13285
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial) -2.1313
FEN1 flap structure-specific endonuclease 1 -2.1298
KIF18A kinesin family member 18A -2.12905
NTAQ1 N-terminal glutamine amidase 1 -2.129
DNAAF5 dynein, axonemal, assembly factor 5 -2.12435
AZIN1 antizyme inhibitor 1 -2.1218
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -2.11635
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -2.1128
HAUS4 HAUS augmin-like complex, subunit 4 -2.112
SRSF2 serine/arginine-rich splicing factor 2 -2.10915
KIAA0586 KIAA0586 -2.10865
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B -2.1058
WDR43 WD repeat domain 43 -2.1058
EPHB2 EPH receptor B2 -2.10545
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.1052
SAP30 Sin3A-associated protein, 30kDa -2.10397
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.1032
RBBP4 retinoblastoma binding protein 4 -2.1026
KLHDC3 kelch domain containing 3 -2.10248
TPX2 TPX2, microtubule-associated -2.10095
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3 -2.1009
UNG uracil-DNA glycosylase -2.0999
FANCG Fanconi anemia, complementation group G -2.0976
RWDD2B RWD domain containing 2B -2.0975
DHFR dihydrofolate reductase -2.09739
CIC capicua transcriptional repressor -2.09695
MKI67 marker of proliferation Ki-67 -2.09665
PRKX protein kinase, X-linked -2.0964
MRPS27 mitochondrial ribosomal protein S27 -2.09625
ACOT2 acyl-CoA thioesterase 2 -2.0958
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.0953
NXT1 nuclear transport factor 2-like export factor 1 -2.0951
GALE UDP-galactose-4-epimerase -2.09505
CHODL chondrolectin -2.0881
GATA4 GATA binding protein 4 -2.08645
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.086
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2 -2.08595
BLM Bloom syndrome, RecQ helicase-like -2.08305
CPAP centrosome assembly and centriole elongation protein -2.0796
INTS13 integrator complex subunit 13 -2.07905
CZIB CXXC motif containing zinc binding protein -2.07735
FKBP4 FK506 binding protein 4, 59kDa -2.07695
CD58 CD58 molecule -2.07628
CCNB1 cyclin B1 -2.0748
ENOPH1 enolase-phosphatase 1 -2.0676
CCNG1 cyclin G1 -2.06745
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -2.06335
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase -2.05562
HJURP Holliday junction recognition protein -2.05545
EHF ets homologous factor -2.05435
PRC1 protein regulator of cytokinesis 1 -2.05415
ZNF250 zinc finger protein 250 -2.0516
LOC128966570 alpha-amylase 1B -2.05125
HMGN4 high mobility group nucleosomal binding domain 4 -2.05125
RPP40 ribonuclease P/MRP 40kDa subunit -2.0472
CEP57 centrosomal protein 57kDa -2.04549
BORA bora, aurora kinase A activator -2.04275
DNAAF2 dynein, axonemal, assembly factor 2 -2.04275
THEM6 thioesterase superfamily member 6 -2.0359
ADAT1 adenosine deaminase, tRNA-specific 1 -2.0342
LAMP5 lysosomal-associated membrane protein family, member 5 -2.03325
TUBGCP4 tubulin, gamma complex associated protein 4 -2.03075
MRPL40 mitochondrial ribosomal protein L40 -2.02983
SLBP stem-loop binding protein -2.02965
ZCCHC10 zinc finger, CCHC domain containing 10 -2.0257
NFYB nuclear transcription factor Y, beta -2.02398
PXMP2 peroxisomal membrane protein 2, 22kDa -2.02205
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.01992
HMGB3 high mobility group box 3 -2.0186
RAB31 RAB31, member RAS oncogene family -2.01587
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.0157
CBX5 chromobox homolog 5 -2.0144
NCALD neurocalcin delta -2.0124
GPSM2 G-protein signaling modulator 2 -2.01115
TTLL12 tubulin tyrosine ligase-like family member 12 -2.0099
RABEPK Rab9 effector protein with kelch motifs -2.0099
NUP43 nucleoporin 43kDa -2.00805
ZNF184 zinc finger protein 184 -2.0034
EXOSC5 exosome component 5 -2.0026