CRCGN017_MCF10A.WT.HP_24H:L01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-nitrotoluene 100.8 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:L01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WFS1 Wolfram syndrome 1 (wolframin) 3.71419
MNAT1 MNAT CDK-activating kinase assembly factor 1 3.46301
EAPP E2F-associated phosphoprotein 3.36792
ZW10 zw10 kinetochore protein 3.25
FGFR4 fibroblast growth factor receptor 4 2.78972
TSEN2 TSEN2 tRNA splicing endonuclease subunit 2.69819
SYNE2 spectrin repeat containing, nuclear envelope 2 2.44358
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.41823
COQ8A coenzyme Q8A 2.10859
SESN1 sestrin 1 2.0475
IGHMBP2 immunoglobulin mu binding protein 2 2.02632

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -5.88368
KRT14 keratin 14, type I -5.32017
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.31032
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.47978
BAG3 BCL2-associated athanogene 3 -3.4236
CHMP4B charged multivesicular body protein 4B -3.39094
ETFB electron-transfer-flavoprotein, beta polypeptide -3.28942
ANXA2 annexin A2 -3.0202
CD58 CD58 molecule -2.99772
DSG2 desmoglein 2 -2.94036
PUF60 poly-U binding splicing factor 60KDa -2.81163
LDHD lactate dehydrogenase D -2.49856
MT2A metallothionein 2A -2.36075
UBE2A ubiquitin-conjugating enzyme E2A -2.20591
UBE3C ubiquitin protein ligase E3C -2.17354