CRCGN017_MCF10A.WT.HP_24H:L03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description o-nitrotoluene 11.2 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:L03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 4.22635
PPARG peroxisome proliferator-activated receptor gamma 3.2287
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2.83585
CCL2 chemokine (C-C motif) ligand 2 2.6755
PRR15L proline rich 15-like 2.47107
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.31567
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.30028
SSBP2 single-stranded DNA binding protein 2 2.18377
COMP cartilage oligomeric matrix protein 2.1818
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.11813
FAM13A family with sequence similarity 13, member A 2.0606

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -5.04368
DERA deoxyribose-phosphate aldolase (putative) -3.58731
TLCD3A TLC domain containing 3A -3.32797
MTERF3 mitochondrial transcription termination factor 3 -3.15835
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -3.05731
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.20282
STXBP1 syntaxin binding protein 1 -2.18517
SORBS3 sorbin and SH3 domain containing 3 -2.12554
GDF15 growth differentiation factor 15 -2.12506
TM9SF2 transmembrane 9 superfamily member 2 -2.01863