| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | bromoethane 33.6 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:L05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AGR2 | anterior gradient 2 | 7.09034 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 5.42483 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 3.47304 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 3.14134 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.05893 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.01909 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.83148 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.81585 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 2.78396 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.69912 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.60459 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) | 2.56591 |
| PLA2G15 | phospholipase A2, group XV | 2.44337 |
| STIMATE | STIM activating enhancer | 2.43213 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.42557 |
| PRKCQ | protein kinase C, theta | 2.41415 |
| PRKX | protein kinase, X-linked | 2.40622 |
| LASP1 | LIM and SH3 protein 1 | 2.35193 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 2.3354 |
| CCDC92 | coiled-coil domain containing 92 | 2.26752 |
| ANKRD40 | ankyrin repeat domain 40 | 2.23352 |
| GRB10 | growth factor receptor-bound protein 10 | 2.2045 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.18303 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.16953 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 2.15568 |
| USP20 | ubiquitin specific peptidase 20 | 2.10138 |
| STK10 | serine/threonine kinase 10 | 2.08425 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 2.06608 |
| DCTN5 | dynactin 5 (p25) | 2.01646 |
| FCHO1 | FCH domain only 1 | 2.01172 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.95076 |
| HSPA8 | heat shock 70kDa protein 8 | -4.52932 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -3.95227 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -3.28597 |
| CYCS | cytochrome c, somatic | -3.20301 |
| CD81 | CD81 molecule | -3.10573 |
| ACOT9 | acyl-CoA thioesterase 9 | -2.98669 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.94789 |
| RPA3 | replication protein A3, 14kDa | -2.85798 |
| UFM1 | ubiquitin-fold modifier 1 | -2.8423 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -2.7614 |
| GOLT1B | golgi transport 1B | -2.71453 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -2.6442 |
| BAG3 | BCL2-associated athanogene 3 | -2.61234 |
| MSMO1 | methylsterol monooxygenase 1 | -2.59325 |
| CAB39 | calcium binding protein 39 | -2.56275 |
| PUF60 | poly-U binding splicing factor 60KDa | -2.5484 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.52837 |
| WASHC5 | WASH complex subunit 5 | -2.48725 |
| CDC45 | cell division cycle 45 | -2.48514 |
| KRT14 | keratin 14, type I | -2.46706 |
| OAT | ornithine aminotransferase | -2.46706 |
| S100A8 | S100 calcium binding protein A8 | -2.46706 |
| ADI1 | acireductone dioxygenase 1 | -2.45682 |
| C1QBP | complement component 1, q subcomponent binding protein | -2.43962 |
| PMM2 | phosphomannomutase 2 | -2.4132 |
| GDF15 | growth differentiation factor 15 | -2.40228 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -2.34298 |
| TENT4A | terminal nucleotidyltransferase 4A | -2.28404 |
| TES | testin LIM domain protein | -2.23106 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.23082 |
| SERHL2 | serine hydrolase-like 2 | -2.21264 |
| TXNDC9 | thioredoxin domain containing 9 | -2.20957 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -2.15881 |
| TUBB6 | tubulin, beta 6 class V | -2.12007 |
| C1QL1 | complement component 1, q subcomponent-like 1 | -2.10222 |
| AMOTL2 | angiomotin like 2 | -2.06706 |
| NDFIP1 | Nedd4 family interacting protein 1 | -2.05857 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -2.05459 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -2.0212 |
