CRCGN017_MCF10A.WT.HP_24H:L06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description bromoethane 11.2 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:L06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MYLK myosin light chain kinase 4.87768
WFS1 Wolfram syndrome 1 (wolframin) 3.94429
ABHD6 abhydrolase domain containing 6 3.75248
FAM20B family with sequence similarity 20, member B 3.62061
KDM5A lysine (K)-specific demethylase 5A 2.80737
WIF1 WNT inhibitory factor 1 2.65729
CXCL2 chemokine (C-X-C motif) ligand 2 2.63664
ACTG2 actin, gamma 2, smooth muscle, enteric 2.61009
CNN1 calponin 1, basic, smooth muscle 2.41828
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.23259
GPER1 G protein-coupled estrogen receptor 1 2.22576
CERK ceramide kinase 2.1736
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.08523

decreased expression

Symbol Name Standardized Value
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -5.33988
PCCB propionyl CoA carboxylase, beta polypeptide -3.98436
EXOSC4 exosome component 4 -2.73077
TLCD3A TLC domain containing 3A -2.72097
ACAA1 acetyl-CoA acyltransferase 1 -2.68671
HSPA1A heat shock 70kDa protein 1A -2.62284
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.42995
TRAPPC3 trafficking protein particle complex 3 -2.31031
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.22667
ITGAV integrin, alpha V -2.01944