CRCGN017_MCF10A.WT.HP_24H:L07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description acrylonitrile 114.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

11 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:L07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EPHB2 EPH receptor B2 4.50916
ACAA1 acetyl-CoA acyltransferase 1 3.31042
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 2.97195
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.15945

decreased expression

Symbol Name Standardized Value
PCCB propionyl CoA carboxylase, beta polypeptide -4.66275
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -3.72015
GDF15 growth differentiation factor 15 -3.58705
RGS2 regulator of G-protein signaling 2 -2.68175
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.51795
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.47787
TRIB3 tribbles pseudokinase 3 -2.09055