CRCGN017_MCF10A.WT.HP_24H:L12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description isoprene 11.09 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

49 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:L12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.8194
TBX2 T-box 2 3.58072
WIF1 WNT inhibitory factor 1 3.174
PLS1 plastin 1 3.00975
AXIN1 axin 1 2.7602
GPATCH8 G patch domain containing 8 2.74067
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.65827
SQOR sulfide quinone oxidoreductase 2.6488
UGDH UDP-glucose 6-dehydrogenase 2.59115
PLAT plasminogen activator, tissue 2.54895
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.33105
MOK MOK protein kinase 2.25965
OLFML2B olfactomedin-like 2B 2.2124
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 2.2024
FZD7 frizzled class receptor 7 2.15562
LHFPL6 LHFPL tetraspan subfamily member 6 2.1289
CTSG cathepsin G 2.0865
SLC75A1 solute carrier family 75 member 1 2.07805
HBB hemoglobin, beta 2.04803
PARP1 poly (ADP-ribose) polymerase 1 2.0152

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -5.1203
PCCB propionyl CoA carboxylase, beta polypeptide -5.1137
TRAPPC3 trafficking protein particle complex 3 -4.9015
NT5DC2 5'-nucleotidase domain containing 2 -4.54965
HSPD1 heat shock 60kDa protein 1 (chaperonin) -4.34532
DCK deoxycytidine kinase -3.73945
VDAC1 voltage-dependent anion channel 1 -3.64145
LYPLA1 lysophospholipase I -3.30667
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.8126
ACAA1 acetyl-CoA acyltransferase 1 -2.58637
ND5 NADH dehydrogenase subunit 5 -2.5382
BAAT bile acid CoA:amino acid N-acyltransferase -2.3956
MRPS15 mitochondrial ribosomal protein S15 -2.38795
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -2.2861
COQ10B coenzyme Q10 homolog B (S. cerevisiae) -2.20245
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.1714
MRPL15 mitochondrial ribosomal protein L15 -2.1495
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 -2.1187
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -2.10755
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 -2.08255
TM4SF4 transmembrane 4 L six family member 4 -2.06625
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -2.06115
COL8A2 collagen, type VIII, alpha 2 -2.05113
WASHC4 WASH complex subunit 4 -2.0333
CFHR2 complement factor H-related 2 -2.02845
ZMYM6 zinc finger, MYM-type 6 -2.02535
NAXD NAD(P)HX dehydratase -2.02255
GIMAP4 GTPase, IMAP family member 4 -2.0005
CD53 CD53 molecule -2.00045