CRCGN017_MCF10A.WT.HP_24H:L14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-nitropropane 32.93 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:L14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 4.61758
SSBP2 single-stranded DNA binding protein 2 4.50527
WIF1 WNT inhibitory factor 1 3.00635
CNRIP1 cannabinoid receptor interacting protein 1 2.96175
STMN2 stathmin 2 2.44012
SESN1 sestrin 1 2.39365
OLFM1 olfactomedin 1 2.09953
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 2.0003

decreased expression

Symbol Name Standardized Value
SGK1 serum/glucocorticoid regulated kinase 1 -5.0
HMG20B high mobility group 20B -4.67017
RXYLT1 ribitol xylosyltransferase 1 -4.2174
SNX7 sorting nexin 7 -2.8596
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.66832
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -2.52405
THAP11 THAP domain containing 11 -2.45875
MAGEA12 melanoma antigen family A12 -2.41725
FASN fatty acid synthase -2.29329
LOC100533997 MAGEA10-MAGEA5 readthrough -2.27715
CSAG2 CSAG family, member 2 -2.2344
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit -2.1475
MAGEA2B melanoma antigen family A2B -2.14245
NGRN neugrin, neurite outgrowth associated -2.1391
MAGEA1 melanoma antigen family A1 -2.07645
HNF4G hepatocyte nuclear factor 4, gamma -2.05765