| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulforaphane 32.62 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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67 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:L23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 6.10985 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 5.6801 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.16355 |
| SKIC8 | SKI8 subunit of superkiller complex | 4.07298 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 3.08135 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 2.8399 |
| EPN2 | epsin 2 | 2.5999 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.5147 |
| H2BC12 | H2B clustered histone 12 | 2.49902 |
| RBBP5 | retinoblastoma binding protein 5 | 2.49005 |
| GLRX | glutaredoxin (thioltransferase) | 2.39127 |
| TBPL1 | TBP-like 1 | 2.36015 |
| PSMD5 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 | 2.3282 |
| PTK2 | protein tyrosine kinase 2 | 2.32048 |
| CHST10 | carbohydrate sulfotransferase 10 | 2.2692 |
| TRIM16 | tripartite motif containing 16 | 2.2472 |
| CRIPT | cysteine-rich PDZ-binding protein | 2.2298 |
| GSR | glutathione reductase | 2.2286 |
| PAK1IP1 | PAK1 interacting protein 1 | 2.19735 |
| POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa | 2.1911 |
| ADPGK | ADP-dependent glucokinase | 2.1851 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.17695 |
| PLPPR1 | phospholipid phosphatase related 1 | 2.12875 |
| SQSTM1 | sequestosome 1 | 2.12455 |
| UGDH | UDP-glucose 6-dehydrogenase | 2.1194 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | 2.089 |
| RBM48 | RNA binding motif protein 48 | 2.08535 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.0465 |
| OGFOD1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | 2.03925 |
| MRPL46 | mitochondrial ribosomal protein L46 | 2.0372 |
| AXIN1 | axin 1 | 2.0201 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HAT1 | histone acetyltransferase 1 | -4.92855 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -4.83635 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.69575 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.2858 |
| STXBP2 | syntaxin binding protein 2 | -3.5724 |
| KRT14 | keratin 14, type I | -3.0241 |
| COG4 | component of oligomeric golgi complex 4 | -2.90765 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -2.8601 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | -2.76525 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.66785 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -2.6561 |
| CCNL2 | cyclin L2 | -2.53635 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -2.4582 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -2.43905 |
| IL22RA1 | interleukin 22 receptor, alpha 1 | -2.3938 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.39215 |
| PLK1 | polo-like kinase 1 | -2.384 |
| MTARC2 | mitochondrial amidoxime reducing component 2 | -2.38005 |
| BAD | BCL2-associated agonist of cell death | -2.34175 |
| EPS8L3 | EPS8-like 3 | -2.32625 |
| GMPS | guanine monphosphate synthase | -2.2722 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 | -2.25585 |
| TUBA4A | tubulin, alpha 4a | -2.23225 |
| CDC20 | cell division cycle 20 | -2.22145 |
| DZIP1 | DAZ interacting zinc finger protein 1 | -2.2109 |
| AURKB | aurora kinase B | -2.2027 |
| GFUS | GDP-L-fucose synthase | -2.19723 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -2.1581 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 | -2.15765 |
| PLD2 | phospholipase D2 | -2.15555 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -2.13935 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -2.074 |
| MICALL2 | MICAL-like 2 | -2.0671 |
| TFF2 | trefoil factor 2 | -2.0313 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) | -2.02665 |
| IMMT | inner membrane protein, mitochondrial | -2.0217 |
