CRCGN017_MCF10A.WT.HP_24H:L24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulforaphane 10.87 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:L24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
UBQLN2 ubiquilin 2 5.78785
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 5.33725
E2F2 E2F transcription factor 2 4.882
PPARG peroxisome proliferator-activated receptor gamma 4.52065
ABHD6 abhydrolase domain containing 6 4.46897
TXNRD1 thioredoxin reductase 1 3.94805
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 3.75277
CNRIP1 cannabinoid receptor interacting protein 1 2.60385
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.3133
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.25978
AGR2 anterior gradient 2 2.21715
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.13535
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.13465
NR0B1 nuclear receptor subfamily 0, group B, member 1 2.12295
UGCG UDP-glucose ceramide glucosyltransferase 2.08503
SSH1 slingshot protein phosphatase 1 2.02802
KEAP1 kelch-like ECH-associated protein 1 2.0052
UNKL unkempt family zinc finger-like 2.0046

decreased expression

Symbol Name Standardized Value
NLRP4 NLR family, pyrin domain containing 4 -4.1945
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.34075
RNF167 ring finger protein 167 -2.91405
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.79017
ACAA1 acetyl-CoA acyltransferase 1 -2.77432
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.32335
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -2.0869
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.07245