CRCGN017_MCF10A.WT.HP_24H:M02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzofuran 34.26 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

31 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:M02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.54673
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.44807
HBA1 hemoglobin, alpha 1 4.27068
HBB hemoglobin, beta 3.20472
CHMP6 charged multivesicular body protein 6 2.73745
XAB2 XPA binding protein 2 2.52453
TCTN1 tectonic family member 1 2.50164
ASL argininosuccinate lyase 2.41556
MTA2 metastasis associated 1 family, member 2 2.39654
GPATCH8 G patch domain containing 8 2.38379
ADGRE5 adhesion G protein-coupled receptor E5 2.38335
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 2.26367
THNSL2 threonine synthase-like 2 (S. cerevisiae) 2.22904
RAB8A RAB8A, member RAS oncogene family 2.04034
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.02953
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.01538

decreased expression

Symbol Name Standardized Value
ITFG1 integrin alpha FG-GAP repeat containing 1 -5.04292
BASP1 brain abundant, membrane attached signal protein 1 -4.43128
MRPS16 mitochondrial ribosomal protein S16 -4.10789
TRAPPC3 trafficking protein particle complex 3 -3.89685
DSG2 desmoglein 2 -3.64914
CD44 CD44 molecule (Indian blood group) -3.59278
CD58 CD58 molecule -3.54623
PARP2 poly (ADP-ribose) polymerase 2 -2.78944
ARID4B AT rich interactive domain 4B (RBP1-like) -2.77196
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -2.35253
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide -2.28852
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa -2.27437
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.27158
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.10655
CORO1A coronin, actin binding protein, 1A -2.07108