CRCGN017_MCF10A.WT.HP_24H:M03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzofuran 11.42 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:M03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 5.61882
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 5.178
PEX11A peroxisomal biogenesis factor 11 alpha 4.40844
CXCL2 chemokine (C-X-C motif) ligand 2 4.28299
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 4.02723
MAMLD1 mastermind-like domain containing 1 3.45576
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 3.37413
KDM5A lysine (K)-specific demethylase 5A 3.08683
TIAM1 T-cell lymphoma invasion and metastasis 1 3.01761
METRN meteorin, glial cell differentiation regulator 2.52181
CDCA4 cell division cycle associated 4 2.18287
NCKIPSD NCK interacting protein with SH3 domain 2.16983

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -4.46278
PCNA proliferating cell nuclear antigen -4.4126
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.24258
HSPA1A heat shock 70kDa protein 1A -3.14909
C1QBP complement component 1, q subcomponent binding protein -2.40599
NGRN neugrin, neurite outgrowth associated -2.26881
THAP11 THAP domain containing 11 -2.19085
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -2.16548
GOLPH3 golgi phosphoprotein 3 (coat-protein) -2.10516
LAD1 ladinin 1 -2.09906
ACAA1 acetyl-CoA acyltransferase 1 -2.02366
BRIX1 BRX1, biogenesis of ribosomes -2.02