| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-diaminoanisole sulfate 34.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
58 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:M05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 5.92624 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) | 4.77948 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 4.57704 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.54551 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 3.97252 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | 3.96726 |
| INTS3 | integrator complex subunit 3 | 3.06051 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.05143 |
| HBB | hemoglobin, beta | 3.00984 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.64759 |
| TBX2 | T-box 2 | 2.63539 |
| FAR2 | fatty acyl CoA reductase 2 | 2.62436 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.59416 |
| SKIC8 | SKI8 subunit of superkiller complex | 2.53097 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.52735 |
| PKN1 | protein kinase N1 | 2.49329 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.39871 |
| SMIM40 | small integral membrane protein 40 | 2.36325 |
| CKMT1A | creatine kinase, mitochondrial 1A | 2.32003 |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | 2.32003 |
| CGREF1 | cell growth regulator with EF-hand domain 1 | 2.28035 |
| IL17RA | interleukin 17 receptor A | 2.26863 |
| RNASE4 | ribonuclease, RNase A family, 4 | 2.26136 |
| NEFM | neurofilament, medium polypeptide | 2.25094 |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta | 2.24854 |
| NEFL | neurofilament, light polypeptide | 2.24316 |
| HBA1 | hemoglobin, alpha 1 | 2.1735 |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 | 2.14149 |
| SNX17 | sorting nexin 17 | 2.09685 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 2.02851 |
| FZD2 | frizzled class receptor 2 | 2.01402 |
| AKIRIN1 | akirin 1 | 2.01077 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT14 | keratin 14, type I | -7.26721 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -6.067 |
| HMG20B | high mobility group 20B | -5.24018 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.18109 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -4.91086 |
| HSPA8 | heat shock 70kDa protein 8 | -4.61136 |
| PRPF4 | pre-mRNA processing factor 4 | -3.31991 |
| LYPLA1 | lysophospholipase I | -3.31126 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.27025 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -3.24465 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.21306 |
| GPKOW | G patch domain and KOW motifs | -3.20332 |
| RBM34 | RNA binding motif protein 34 | -2.59268 |
| NGRN | neugrin, neurite outgrowth associated | -2.38782 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase | -2.34222 |
| APOL1 | apolipoprotein L, 1 | -2.26243 |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 | -2.24486 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -2.22557 |
| RHOBTB2 | Rho-related BTB domain containing 2 | -2.20719 |
| ALDH8A1 | aldehyde dehydrogenase 8 family, member A1 | -2.18851 |
| HOXC11 | homeobox C11 | -2.11616 |
| CSRP1 | cysteine and glycine-rich protein 1 | -2.09398 |
| AKIP1 | A kinase (PRKA) interacting protein 1 | -2.05933 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 | -2.0328 |
| ADSS2 | adenylosuccinate synthase 2 | -2.03167 |
| RAB29 | RAB29, member RAS oncogene family | -2.00414 |
