| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | chlordane 11.09 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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140 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:M09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| WIF1 | WNT inhibitory factor 1 | 6.53325 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.1398 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 4.85075 |
| HBB | hemoglobin, beta | 4.3849 |
| ADRB2 | adrenoceptor beta 2, surface | 4.35415 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.26895 |
| HBA1 | hemoglobin, alpha 1 | 3.88951 |
| ECD | ecdysoneless homolog (Drosophila) | 3.4501 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 3.40635 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 3.35075 |
| SQOR | sulfide quinone oxidoreductase | 3.29885 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 2.9536 |
| CA3 | carbonic anhydrase III | 2.87015 |
| GPATCH8 | G patch domain containing 8 | 2.85915 |
| ZNF451 | zinc finger protein 451 | 2.84965 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 2.772 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 2.6721 |
| HAT1 | histone acetyltransferase 1 | 2.66255 |
| COMP | cartilage oligomeric matrix protein | 2.60725 |
| SMIM41 | small integral membrane protein 41 | 2.5126 |
| DENND2D | DENN/MADD domain containing 2D | 2.50035 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 2.49395 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 2.44707 |
| RPL10A | ribosomal protein L10a | 2.42675 |
| DCAF4 | DDB1 and CUL4 associated factor 4 | 2.4053 |
| PALMD | palmdelphin | 2.4035 |
| BRD7 | bromodomain containing 7 | 2.35555 |
| LRRC1 | leucine rich repeat containing 1 | 2.3474 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | 2.3449 |
| RBBP5 | retinoblastoma binding protein 5 | 2.2984 |
| SLN | sarcolipin | 2.293 |
| FZD10 | frizzled class receptor 10 | 2.28715 |
| PLA2G12A | phospholipase A2, group XIIA | 2.2812 |
| GATA4 | GATA binding protein 4 | 2.2754 |
| PIK3C3 | phosphatidylinositol 3-kinase, catalytic subunit type 3 | 2.26522 |
| SLC5A7 | solute carrier family 5 (sodium/choline cotransporter), member 7 | 2.22315 |
| PRSS23 | protease, serine, 23 | 2.207 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 | 2.1967 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) | 2.17537 |
| EMP2 | epithelial membrane protein 2 | 2.17315 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | 2.17185 |
| UGT2B10 | UDP glucuronosyltransferase 2 family, polypeptide B10 | 2.17175 |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial | 2.16075 |
| GTPBP8 | GTP-binding protein 8 (putative) | 2.1543 |
| ZNF552 | zinc finger protein 552 | 2.15085 |
| SETD6 | SET domain containing 6 | 2.13175 |
| MAD2L1BP | MAD2L1 binding protein | 2.1293 |
| METTL22 | methyltransferase like 22 | 2.1207 |
| TOPBP1 | topoisomerase (DNA) II binding protein 1 | 2.12015 |
| CCL16 | chemokine (C-C motif) ligand 16 | 2.11425 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 2.11185 |
| CYB5A | cytochrome b5 type A (microsomal) | 2.11153 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 2.07605 |
| RLN2 | relaxin 2 | 2.06615 |
| APOC1 | apolipoprotein C-I | 2.06572 |
| EPHA4 | EPH receptor A4 | 2.05555 |
| SPATA5L1 | spermatogenesis associated 5-like 1 | 2.0541 |
| PEG3 | paternally expressed 3 | 2.04865 |
| DCAF13 | DDB1 and CUL4 associated factor 13 | 2.0468 |
| EXT1 | exostosin glycosyltransferase 1 | 2.0279 |
| NIF3L1 | NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) | 2.0264 |
| THEM6 | thioesterase superfamily member 6 | 2.0249 |
| RRH | retinal pigment epithelium-derived rhodopsin homolog | 2.0228 |
| UBXN8 | UBX domain protein 8 | 2.0201 |
| IFT52 | intraflagellar transport 52 | 2.01465 |
| PRKCQ | protein kinase C, theta | 2.01452 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 2.01345 |
| NKRF | NFKB repressing factor | 2.01265 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 2.0089 |
| CCKBR | cholecystokinin B receptor | 2.0076 |
| MBD5 | methyl-CpG binding domain protein 5 | 2.00255 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT14 | keratin 14, type I | -6.0866 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -5.7858 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -5.6675 |
| ACOT9 | acyl-CoA thioesterase 9 | -5.4575 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -5.214 |
| MT2A | metallothionein 2A | -5.10855 |
| HMG20B | high mobility group 20B | -4.90168 |
| TLCD3A | TLC domain containing 3A | -4.88855 |
| CYCS | cytochrome c, somatic | -4.7976 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.7448 |
| MSN | moesin | -4.72835 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -4.5004 |
| TRAPPC3 | trafficking protein particle complex 3 | -4.28648 |
| TUBA4A | tubulin, alpha 4a | -4.23445 |
| CANT1 | calcium activated nucleotidase 1 | -3.99258 |
| PFN1 | profilin 1 | -3.8257 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -3.3449 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -3.33735 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -3.31765 |
| CD81 | CD81 molecule | -3.27855 |
| ELAC2 | elaC ribonuclease Z 2 | -3.1949 |
| STXBP2 | syntaxin binding protein 2 | -3.04145 |
| XPO7 | exportin 7 | -2.7773 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -2.741 |
| CD320 | CD320 molecule | -2.68565 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -2.6717 |
| ILK | integrin-linked kinase | -2.6417 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | -2.61065 |
| BSG | basigin (Ok blood group) | -2.59825 |
| EXOSC4 | exosome component 4 | -2.55918 |
| TIMM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) | -2.48977 |
| MAP7D1 | MAP7 domain containing 1 | -2.4769 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -2.45705 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 | -2.43305 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -2.417 |
| MT1X | metallothionein 1X | -2.3773 |
| MED15 | mediator complex subunit 15 | -2.3559 |
| NECTIN2 | nectin cell adhesion molecule 2 | -2.33615 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | -2.33365 |
| ATF5 | activating transcription factor 5 | -2.3119 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | -2.31165 |
| LOC112694756 | uncharaterized LOC112694756 | -2.2578 |
| SETD1B | SET domain containing 1B | -2.2535 |
| DNM2 | dynamin 2 | -2.2523 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -2.2418 |
| MRPS15 | mitochondrial ribosomal protein S15 | -2.22955 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | -2.1896 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | -2.13945 |
| HSPA1A | heat shock 70kDa protein 1A | -2.13805 |
| MVP | major vault protein | -2.1334 |
| NADK | NAD kinase | -2.11795 |
| FAM222B | family with sequence similarity 222, member B | -2.1118 |
| ATP5F1B | ATP synthase F1 subunit beta | -2.1111 |
| NISCH | nischarin | -2.1047 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | -2.1033 |
| REEP5 | receptor accessory protein 5 | -2.09235 |
| PRR13 | proline rich 13 | -2.08165 |
| INTS3 | integrator complex subunit 3 | -2.0769 |
| AARS1 | alanyl-tRNA synthetase 1 | -2.07545 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | -2.07015 |
| DAPK3 | death-associated protein kinase 3 | -2.04098 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | -2.03142 |
| MCOLN1 | mucolipin 1 | -2.0252 |
| TAC4 | tachykinin 4 (hemokinin) | -2.02165 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | -2.0142 |
| TMEM134 | transmembrane protein 134 | -2.00995 |
| CRTAP | cartilage associated protein | -2.0093 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.00755 |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 | -2.00295 |
