CRCGN017_MCF10A.WT.HP_24H:M12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description styrene 10.98 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

79 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:M12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 5.2304
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 5.11107
ABHD4 abhydrolase domain containing 4 4.83835
GARRE1 granule associated Rac and RHOG effector 1 3.93715
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.1095
NOSIP nitric oxide synthase interacting protein 2.90185
PCNT pericentrin 2.7849
METRN meteorin, glial cell differentiation regulator 2.52955
CENPE centromere protein E, 312kDa 2.2267
PIAS3 protein inhibitor of activated STAT, 3 2.15435
LPL lipoprotein lipase 2.14595
PCBP1 poly(rC) binding protein 1 2.13745
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 2.13635
TMPRSS11D transmembrane protease, serine 11D 2.1025
EMC6 ER membrane protein complex subunit 6 2.08645
S100A10 S100 calcium binding protein A10 2.02935
ACIN1 apoptotic chromatin condensation inducer 1 2.0008

decreased expression

Symbol Name Standardized Value
NT5DC2 5'-nucleotidase domain containing 2 -8.2993
MSMO1 methylsterol monooxygenase 1 -5.92035
TM9SF3 transmembrane 9 superfamily member 3 -5.66475
PCNA proliferating cell nuclear antigen -5.0
BAG3 BCL2-associated athanogene 3 -4.92945
GTPBP8 GTP-binding protein 8 (putative) -4.9219
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -4.83278
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.83255
DSG2 desmoglein 2 -4.55595
PRPF4 pre-mRNA processing factor 4 -3.982
SNX7 sorting nexin 7 -3.5442
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -3.29288
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -3.19743
BAD BCL2-associated agonist of cell death -3.17537
SMC1A structural maintenance of chromosomes 1A -3.05635
CNTN1 contactin 1 -2.91385
BASP1 brain abundant, membrane attached signal protein 1 -2.87145
DROSHA drosha, ribonuclease type III -2.8554
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.81367
FOS FBJ murine osteosarcoma viral oncogene homolog -2.761
EXOC3 exocyst complex component 3 -2.72455
ACAA1 acetyl-CoA acyltransferase 1 -2.67365
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.62755
GDF15 growth differentiation factor 15 -2.62015
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.5977
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 -2.5097
SLC44A1 solute carrier family 44 (choline transporter), member 1 -2.5091
ZNF623 zinc finger protein 623 -2.48275
COL16A1 collagen, type XVI, alpha 1 -2.46665
TMEM267 transmembrane protein 267 -2.451
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -2.4494
NARS1 asparaginyl-tRNA synthetase 1 -2.3816
DKK1 dickkopf WNT signaling pathway inhibitor 1 -2.3634
RTCA RNA 3'-terminal phosphate cyclase -2.3511
PANK2 pantothenate kinase 2 -2.3467
PLA2G12A phospholipase A2, group XIIA -2.31495
AQP4 aquaporin 4 -2.2652
TASP1 taspase, threonine aspartase, 1 -2.242
ZBED2 zinc finger, BED-type containing 2 -2.2262
ZNF7 zinc finger protein 7 -2.2118
PAIP1 poly(A) binding protein interacting protein 1 -2.19122
INSL4 insulin-like 4 (placenta) -2.1667
ZNF671 zinc finger protein 671 -2.1645
SLC12A7 solute carrier family 12 (potassium/chloride transporter), member 7 -2.144
ZNF304 zinc finger protein 304 -2.13285
WDR73 WD repeat domain 73 -2.12725
ZNF721 zinc finger protein 721 -2.12595
MLH1 mutL homolog 1 -2.11345
SPATA7 spermatogenesis associated 7 -2.1128
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 -2.09985
ARSL arylsulfatase L -2.09825
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 -2.09665
LIFR leukemia inhibitory factor receptor alpha -2.09225
TIMCC TIM double twin CX3C motif chaperone -2.0685
HSPA6 heat shock 70kDa protein 6 (HSP70B') -2.06427
KLK5 kallikrein-related peptidase 5 -2.0638
NME6 NME/NM23 nucleoside diphosphate kinase 6 -2.06305
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.0503
SPAG1 sperm associated antigen 1 -2.0485
SOX12 SRY (sex determining region Y)-box 12 -2.03495
FBXL7 F-box and leucine-rich repeat protein 7 -2.0275
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 -2.0123