| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-amino-5-(5-nitro-2-furyl)-1,3,4-oxadiazole 11.11 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
63 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:M15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 5.04135 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 4.8666 |
| STK10 | serine/threonine kinase 10 | 4.66815 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.66275 |
| ABHD4 | abhydrolase domain containing 4 | 4.57405 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 4.56575 |
| FZD7 | frizzled class receptor 7 | 4.46577 |
| NNT | nicotinamide nucleotide transhydrogenase | 4.16603 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.7992 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.5747 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 3.17357 |
| METRN | meteorin, glial cell differentiation regulator | 3.0009 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 2.82693 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.82298 |
| MCCC1 | methylcrotonoyl-CoA carboxylase 1 (alpha) | 2.48615 |
| SATB1 | SATB homeobox 1 | 2.39055 |
| PTK7 | protein tyrosine kinase 7 (inactive) | 2.28935 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 | 2.2783 |
| GSDMD | gasdermin D | 2.2479 |
| CLIC3 | chloride intracellular channel 3 | 2.2279 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 2.20645 |
| HBA1 | hemoglobin, alpha 1 | 2.20217 |
| PRR15L | proline rich 15-like | 2.1862 |
| MATN4 | matrilin 4 | 2.16405 |
| CCNA1 | cyclin A1 | 2.16395 |
| EVL | Enah/Vasp-like | 2.1571 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) | 2.142 |
| HBB | hemoglobin, beta | 2.08822 |
| CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 | 2.0492 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.03533 |
| ZNF84 | zinc finger protein 84 | 2.02995 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 2.0 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPIA | ribose 5-phosphate isomerase A | -9.0656 |
| GDF15 | growth differentiation factor 15 | -6.7563 |
| BAG3 | BCL2-associated athanogene 3 | -5.5875 |
| COG2 | component of oligomeric golgi complex 2 | -5.09135 |
| GLRX | glutaredoxin (thioltransferase) | -5.05653 |
| S100A8 | S100 calcium binding protein A8 | -5.0 |
| UFM1 | ubiquitin-fold modifier 1 | -4.9863 |
| VAT1 | vesicle amine transport 1 | -4.91265 |
| UBE3C | ubiquitin protein ligase E3C | -4.87945 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.12455 |
| HMG20B | high mobility group 20B | -4.09347 |
| SNX7 | sorting nexin 7 | -4.06325 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.82635 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.34075 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.03077 |
| HSPA1A | heat shock 70kDa protein 1A | -2.9302 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.79205 |
| RAD51C | RAD51 paralog C | -2.7706 |
| ATF6 | activating transcription factor 6 | -2.58717 |
| DCLK1 | doublecortin-like kinase 1 | -2.52208 |
| RHOBTB1 | Rho-related BTB domain containing 1 | -2.44145 |
| PROSER1 | proline and serine rich 1 | -2.3974 |
| PLA1A | phospholipase A1 member A | -2.33565 |
| MRPS31 | mitochondrial ribosomal protein S31 | -2.33542 |
| QPCT | glutaminyl-peptide cyclotransferase | -2.2747 |
| GSTT1 | glutathione S-transferase theta 1 | -2.26665 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -2.20015 |
| DUSP4 | dual specificity phosphatase 4 | -2.18445 |
| ALX1 | ALX homeobox 1 | -2.1712 |
| KRT1 | keratin 1, type II | -2.1636 |
| ASB9 | ankyrin repeat and SOCS box containing 9 | -2.04795 |