CRCGN017_MCF10A.WT.HP_24H:M16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo[c]phenanthrene 102.22 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:M16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CASP2 caspase 2, apoptosis-related cysteine peptidase 3.86971
TIAM1 T-cell lymphoma invasion and metastasis 1 3.27515
CNRIP1 cannabinoid receptor interacting protein 1 2.98885
NUTF2 nuclear transport factor 2 2.69175
USP6NL USP6 N-terminal like 2.62525
ELP3 elongator acetyltransferase complex subunit 3 2.43115
CCL2 chemokine (C-C motif) ligand 2 2.4032
NOSIP nitric oxide synthase interacting protein 2.2745
EVL Enah/Vasp-like 2.1806
SAE1 SUMO1 activating enzyme subunit 1 2.11415
ZMIZ1 zinc finger, MIZ-type containing 1 2.07415
WDR76 WD repeat domain 76 2.05825
METRN meteorin, glial cell differentiation regulator 2.01065

decreased expression

Symbol Name Standardized Value
TXNDC9 thioredoxin domain containing 9 -5.02117
HMG20B high mobility group 20B -4.8395
BAG3 BCL2-associated athanogene 3 -4.45435
SNX7 sorting nexin 7 -4.4332
RXYLT1 ribitol xylosyltransferase 1 -3.8178
COPS7A COP9 signalosome subunit 7A -3.793
TRAPPC3 trafficking protein particle complex 3 -3.54465
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.0793
UNC50 unc-50 homolog (C. elegans) -2.99235
CREG1 cellular repressor of E1A-stimulated genes 1 -2.54675
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated -2.2349
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.20215
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.1321