CRCGN017_MCF10A.WT.HP_24H:M17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo[c]phenanthrene 34.07 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:M17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 4.44091
CXCR4 chemokine (C-X-C motif) receptor 4 4.31948
ABHD6 abhydrolase domain containing 6 3.96668
IGHMBP2 immunoglobulin mu binding protein 2 3.50423
ARID5B AT rich interactive domain 5B (MRF1-like) 3.19095
SNCA synuclein, alpha (non A4 component of amyloid precursor) 3.08923
FGFR4 fibroblast growth factor receptor 4 2.64092
OLFML2B olfactomedin-like 2B 2.6013
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.3658
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.2939
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.09145
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) 2.08435
RPP38 ribonuclease P/MRP 38kDa subunit 2.06345
COQ8A coenzyme Q8A 2.0145

decreased expression

Symbol Name Standardized Value
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -5.03485
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.72965
PARP2 poly (ADP-ribose) polymerase 2 -4.22635
APIP APAF1 interacting protein -2.74135
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.61205
METTL17 methyltransferase like 17 -2.3546
PRCP prolylcarboxypeptidase (angiotensinase C) -2.05835
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A -2.02455
FBXO3 F-box protein 3 -2.0057