CRCGN017_MCF10A.WT.HP_24H:M18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo[c]phenanthrene 11.36 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:M18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 4.61252
RB1 retinoblastoma 1 2.7307
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.63493
WIF1 WNT inhibitory factor 1 2.33595
TPD52L2 tumor protein D52-like 2 2.2721
NSG2 neuronal vesicle trafficking associated 2 2.12025
CD40LG CD40 ligand 2.0829

decreased expression

Symbol Name Standardized Value
SGK1 serum/glucocorticoid regulated kinase 1 -4.7457
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -4.5603
DNM1L dynamin 1-like -4.45355
TRIB3 tribbles pseudokinase 3 -3.74975
TLCD3A TLC domain containing 3A -3.42735
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -3.4184
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.95235
NGRN neugrin, neurite outgrowth associated -2.8526
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -2.46855
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -2.40003
ACAA1 acetyl-CoA acyltransferase 1 -2.33075
RAI14 retinoic acid induced 14 -2.28075
SNX7 sorting nexin 7 -2.2506
VPS33B vacuolar protein sorting 33 homolog B (yeast) -2.13342
CSRP1 cysteine and glycine-rich protein 1 -2.05102
UPK2 uroplakin 2 -2.02415