| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | penicillin-v-potassium 11.21 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
74 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:M21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PEX11A | peroxisomal biogenesis factor 11 alpha | 4.9758 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 4.779 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.61522 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 3.807 |
| CBR1 | carbonyl reductase 1 | 2.9636 |
| SNX11 | sorting nexin 11 | 2.76155 |
| ELP4 | elongator acetyltransferase complex subunit 4 | 2.7118 |
| OLFM1 | olfactomedin 1 | 2.55463 |
| WIF1 | WNT inhibitory factor 1 | 2.49475 |
| STATH | statherin | 2.47305 |
| MUC7 | mucin 7, secreted | 2.3378 |
| HBB | hemoglobin, beta | 2.3217 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 2.26445 |
| ODAM | odontogenic, ameloblast asssociated | 2.2415 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 2.2323 |
| HSPB2 | heat shock 27kDa protein 2 | 2.1637 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | 2.11735 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa | 2.11495 |
| DCAF11 | DDB1 and CUL4 associated factor 11 | 2.10385 |
| NDUFB11 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa | 2.10125 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 2.08925 |
| SMR3B | submaxillary gland androgen regulated protein 3B | 2.06805 |
| CRIPT | cysteine-rich PDZ-binding protein | 2.06675 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | 2.0659 |
| PIR | pirin (iron-binding nuclear protein) | 2.065 |
| CSNK1A1 | casein kinase 1, alpha 1 | 2.06319 |
| HSPB7 | heat shock 27kDa protein family, member 7 (cardiovascular) | 2.05545 |
| CRYAB | crystallin, alpha B | 2.04375 |
| FAM53C | family with sequence similarity 53, member C | 2.042 |
| LPO | lactoperoxidase | 2.02055 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 | 2.0173 |
| PEX13 | peroxisomal biogenesis factor 13 | 2.0163 |
| GALK1 | galactokinase 1 | 2.01175 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT14 | keratin 14, type I | -7.1351 |
| COG2 | component of oligomeric golgi complex 2 | -5.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.69575 |
| MSN | moesin | -3.83255 |
| RNF167 | ring finger protein 167 | -3.54265 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.5364 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -3.31729 |
| FTSJ3 | FtsJ homolog 3 (E. coli) | -2.8851 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.83685 |
| CD320 | CD320 molecule | -2.8304 |
| WASHC4 | WASH complex subunit 4 | -2.75985 |
| TRAPPC14 | trafficking protein particle complex subunit 14 | -2.4909 |
| UPP1 | uridine phosphorylase 1 | -2.45505 |
| PFN1 | profilin 1 | -2.43455 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -2.41743 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.36335 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.35355 |
| KAT2A | K(lysine) acetyltransferase 2A | -2.33615 |
| BAAT | bile acid CoA:amino acid N-acyltransferase | -2.31025 |
| WDR26 | WD repeat domain 26 | -2.27505 |
| KRT6B | keratin 6B, type II | -2.2533 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) | -2.2376 |
| SETD6 | SET domain containing 6 | -2.23045 |
| TTC13 | tetratricopeptide repeat domain 13 | -2.22915 |
| TRIB3 | tribbles pseudokinase 3 | -2.2239 |
| KRT6A | keratin 6A, type II | -2.14212 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -2.12915 |
| HDHD5 | haloacid dehalogenase like hydrolase domain containing 5 | -2.1214 |
| TMPRSS11E | transmembrane protease, serine 11E | -2.10285 |
| TWNK | twinkle mtDNA helicase | -2.09375 |
| SMC6 | structural maintenance of chromosomes 6 | -2.086 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.083 |
| TKTL1 | transketolase-like 1 | -2.0746 |
| CPTP | ceramide-1-phosphate transfer protein | -2.07195 |
| MAGEC2 | melanoma antigen family C2 | -2.05315 |
| TMEM121 | transmembrane protein 121 | -2.053 |
| ZNF324 | zinc finger protein 324 | -2.02425 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 | -2.0206 |
| UTP25 | UTP25 small subunit processome component | -2.00755 |
| AQP6 | aquaporin 6, kidney specific | -2.00723 |
| LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | -2.00365 |
