CRCGN017_MCF10A.WT.HP_24H:N07 Gene Set
Genes
39 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:N07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
5.10325
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.7148
|
|
SLC37A4
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4
|
4.00555
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.58535
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
3.4259
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.7562
|
|
NPIPA6
|
nuclear pore complex interacting protein family, member A6
|
2.3826
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.37435
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
2.34575
|
|
FBXO11
|
F-box protein 11
|
2.31525
|
|
KIT
|
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
2.29325
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.25812
|
|
TMEM176B
|
transmembrane protein 176B
|
2.2224
|
|
HAAO
|
3-hydroxyanthranilate 3,4-dioxygenase
|
2.1995
|
|
TMEM176A
|
transmembrane protein 176A
|
2.18795
|
|
DCAF13
|
DDB1 and CUL4 associated factor 13
|
2.1276
|
|
OLFML2B
|
olfactomedin-like 2B
|
2.0568
|
|
UBAC1
|
UBA domain containing 1
|
2.0462
|
|
WIF1
|
WNT inhibitory factor 1
|
2.0361
|
|
CDH11
|
cadherin 11, type 2, OB-cadherin (osteoblast)
|
2.03327
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
2.0042
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DSG2
|
desmoglein 2
|
-10.0
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-5.33725
|
|
ECH1
|
enoyl CoA hydratase 1, peroxisomal
|
-4.92035
|
|
BAG3
|
BCL2-associated athanogene 3
|
-4.90955
|
|
SNX7
|
sorting nexin 7
|
-4.4347
|
|
PMM2
|
phosphomannomutase 2
|
-4.12245
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
-3.88578
|
|
HAT1
|
histone acetyltransferase 1
|
-3.69965
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
-3.66095
|
|
STXBP2
|
syntaxin binding protein 2
|
-3.6504
|
|
UQCR10
|
ubiquinol-cytochrome c reductase, complex III subunit X
|
-3.60585
|
|
RPA3
|
replication protein A3, 14kDa
|
-3.18285
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
-2.8702
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
-2.70893
|
|
P2RX5
|
purinergic receptor P2X, ligand gated ion channel, 5
|
-2.625
|
|
SLC35B1
|
solute carrier family 35, member B1
|
-2.27325
|
|
PLEKHB1
|
pleckstrin homology domain containing, family B (evectins) member 1
|
-2.22785
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
-2.0145
|