CRCGN017_MCF10A.WT.HP_24H:N08 Gene Set
Genes
45 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:N08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CCNA1
|
cyclin A1
|
5.54775
|
|
LOXL1
|
lysyl oxidase-like 1
|
4.8677
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
4.75077
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.5083
|
|
STAT3
|
signal transducer and activator of transcription 3 (acute-phase response factor)
|
4.44785
|
|
WIF1
|
WNT inhibitory factor 1
|
3.8596
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
3.7717
|
|
KLHL21
|
kelch-like family member 21
|
3.62425
|
|
CHEK1
|
checkpoint kinase 1
|
3.48347
|
|
HBB
|
hemoglobin, beta
|
3.29705
|
|
WASF3
|
WAS protein family, member 3
|
3.2391
|
|
TBX2
|
T-box 2
|
3.13583
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
2.9712
|
|
USP6NL
|
USP6 N-terminal like
|
2.88355
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.83695
|
|
MTA2
|
metastasis associated 1 family, member 2
|
2.7722
|
|
RBBP5
|
retinoblastoma binding protein 5
|
2.5851
|
|
STT3A
|
STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
|
2.5487
|
|
GSTK1
|
glutathione S-transferase kappa 1
|
2.39215
|
|
HBA1
|
hemoglobin, alpha 1
|
2.37707
|
|
LHFPL6
|
LHFPL tetraspan subfamily member 6
|
2.31095
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
2.28525
|
|
TRIM5
|
tripartite motif containing 5
|
2.2811
|
|
PLTP
|
phospholipid transfer protein
|
2.2701
|
|
NUTF2
|
nuclear transport factor 2
|
2.15505
|
|
ZW10
|
zw10 kinetochore protein
|
2.1107
|
|
XKR8
|
XK, Kell blood group complex subunit-related family, member 8
|
2.0782
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
2.06395
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
-4.93067
|
|
CCNB1
|
cyclin B1
|
-4.81075
|
|
HMG20B
|
high mobility group 20B
|
-4.69945
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.60555
|
|
NLRP4
|
NLR family, pyrin domain containing 4
|
-3.26765
|
|
PLK1
|
polo-like kinase 1
|
-3.07505
|
|
HS2ST1
|
heparan sulfate 2-O-sulfotransferase 1
|
-2.98055
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-2.9455
|
|
GDF15
|
growth differentiation factor 15
|
-2.79415
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.74945
|
|
METTL17
|
methyltransferase like 17
|
-2.41325
|
|
RPA3
|
replication protein A3, 14kDa
|
-2.3633
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
-2.24775
|
|
ADGRL3
|
adhesion G protein-coupled receptor L3
|
-2.13265
|
|
MGAT4A
|
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
|
-2.1306
|
|
FAM169A
|
family with sequence similarity 169, member A
|
-2.0403
|
|
BCHE
|
butyrylcholinesterase
|
-2.00425
|