CRCGN017_MCF10A.WT.HP_24H:N10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description griseofulvin 100.55 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

566 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:N10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MSRA methionine sulfoxide reductase A 6.22645
H2BC12 H2B clustered histone 12 6.01543
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.90745
WIF1 WNT inhibitory factor 1 5.86925
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 5.0767
CXCL2 chemokine (C-X-C motif) ligand 2 4.3341
PTPN1 protein tyrosine phosphatase, non-receptor type 1 4.2652
MAMLD1 mastermind-like domain containing 1 4.1928
H2BC9 H2B clustered histone 9 4.1352
H1-2 H1.2 linker histone, cluster member 3.8626
CDPF1 cysteine-rich, DPF motif domain containing 1 3.60225
NOTCH1 notch 1 3.4997
DHRS2 dehydrogenase/reductase (SDR family) member 2 3.4623
CEMIP2 cell migration inducing hyaluronidase 2 3.4526
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 3.4525
H2BC4 H2B clustered histone 4 3.34054
RGS2 regulator of G-protein signaling 2 3.2878
H2BC5 H2B clustered histone 5 3.27432
OXSR1 oxidative stress responsive 1 3.21725
MAST2 microtubule associated serine/threonine kinase 2 3.1886
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 3.1852
H2BC21 H2B clustered histone 21 3.12495
JUN jun proto-oncogene 3.0768
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 3.0146
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.98962
H2AC6 H2A clustered histone 6 2.9784
TBPL1 TBP-like 1 2.9755
CADM1 cell adhesion molecule 1 2.93422
BAMBI BMP and activin membrane-bound inhibitor 2.8793
DENND5B DENN/MADD domain containing 5B 2.86585
MAPKBP1 mitogen-activated protein kinase binding protein 1 2.8306
H2AC19 H2A clustered histone 19 2.80735
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.8021
TBL1Y transducin (beta)-like 1, Y-linked 2.7799
STX4 syntaxin 4 2.7687
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 2.7532
TERF2IP telomeric repeat binding factor 2, interacting protein 2.7374
FAT1 FAT atypical cadherin 1 2.73715
FCHO1 FCH domain only 1 2.73265
CTSE cathepsin E 2.732
TPST2 tyrosylprotein sulfotransferase 2 2.73065
H2AC7 H2A clustered histone 7 2.67905
TERT telomerase reverse transcriptase 2.67585
UBQLN2 ubiquilin 2 2.67395
PRKCQ protein kinase C, theta 2.66467
ZNF667 zinc finger protein 667 2.65795
GSDMB gasdermin B 2.64965
S100A4 S100 calcium binding protein A4 2.6421
KLRC3 killer cell lectin-like receptor subfamily C, member 3 2.6278
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.6218
ZC2HC1A zinc finger, C2HC-type containing 1A 2.6121
GRIA3 glutamate receptor, ionotropic, AMPA 3 2.61157
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa 2.607
UGDH UDP-glucose 6-dehydrogenase 2.60195
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 2.59845
OR2B6 olfactory receptor, family 2, subfamily B, member 6 2.5715
DCAF13 DDB1 and CUL4 associated factor 13 2.55575
DLX5 distal-less homeobox 5 2.55035
MACO1 macoilin 1 2.54515
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 2.54128
KLRF1 killer cell lectin-like receptor subfamily F, member 1 2.5376
VASP vasodilator-stimulated phosphoprotein 2.52485
EDN3 endothelin 3 2.52295
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 2.5225
H2BC3 H2B clustered histone 3 2.51785
CERT1 ceramide transporter 1 2.51465
ASXL3 additional sex combs like transcriptional regulator 3 2.5146
CLDN8 claudin 8 2.5089
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.50415
DOCK3 dedicator of cytokinesis 3 2.5025
USP9Y ubiquitin specific peptidase 9, Y-linked 2.49895
CPQ carboxypeptidase Q 2.49845
FGFR4 fibroblast growth factor receptor 4 2.49265
VENTX VENT homeobox 2.49105
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 2.48255
TXNL4B thioredoxin-like 4B 2.47825
ZNF124 zinc finger protein 124 2.47605
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 2.4732
ZNF155 zinc finger protein 155 2.472
MOK MOK protein kinase 2.46935
PAX8 paired box 8 2.46699
APOBR apolipoprotein B receptor 2.4551
GHR growth hormone receptor 2.45395
PTGDR prostaglandin D2 receptor (DP) 2.4484
CNKSR3 CNKSR family member 3 2.44795
PPT1 palmitoyl-protein thioesterase 1 2.44445
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 2.4435
CRYBA2 crystallin, beta A2 2.43575
PPP1R9A protein phosphatase 1, regulatory subunit 9A 2.43355
ZFY zinc finger protein, Y-linked 2.4335
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 2.43232
CAMK1D calcium/calmodulin-dependent protein kinase ID 2.4254
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.4215
AQP8 aquaporin 8 2.42085
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 2.4176
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.4109
SERGEF secretion regulating guanine nucleotide exchange factor 2.41015
CRYBA4 crystallin, beta A4 2.40735
RASAL2 RAS protein activator like 2 2.397
PNMA8A PNMA family member 8A 2.39555
B3GALT5 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 2.391
PRKCE protein kinase C, epsilon 2.3845
PYY peptide YY 2.37775
BSDC1 BSD domain containing 1 2.36608
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 2.36603
TRAPPC6A trafficking protein particle complex 6A 2.36455
HPGDS hematopoietic prostaglandin D synthase 2.36405
INPP5J inositol polyphosphate-5-phosphatase J 2.35485
RASA2 RAS p21 protein activator 2 2.3528
LPAR6 lysophosphatidic acid receptor 6 2.35135
PARM1 prostate androgen-regulated mucin-like protein 1 2.34635
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.34308
PID1 phosphotyrosine interaction domain containing 1 2.341
FCGBP Fc fragment of IgG binding protein 2.3286
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 2.3273
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.32725
NECAP1 NECAP endocytosis associated 1 2.32695
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7 2.32602
AP1G1 adaptor-related protein complex 1, gamma 1 subunit 2.3249
ADGRG3 adhesion G protein-coupled receptor G3 2.32405
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 2.3227
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.31855
TAS2R1 taste receptor, type 2, member 1 2.31655
KLHDC8A kelch domain containing 8A 2.3161
ATG4A autophagy related 4A, cysteine peptidase 2.3151
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 2.3134
RASL11B RAS-like, family 11, member B 2.31235
MON1B MON1 secretory trafficking family member B 2.3121
CPLX2 complexin 2 2.31045
CLEC5A C-type lectin domain family 5, member A 2.3097
ZBTB7C zinc finger and BTB domain containing 7C 2.3066
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 2.30192
NKAIN1 Na+/K+ transporting ATPase interacting 1 2.29825
MMP7 matrix metallopeptidase 7 2.29485
PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.29385
GLRX glutaredoxin (thioltransferase) 2.2938
PDE12 phosphodiesterase 12 2.2929
CXCL3 chemokine (C-X-C motif) ligand 3 2.29135
ANTKMT adenine nucleotide translocase lysine methyltransferase 2.2911
PLA2G15 phospholipase A2, group XV 2.2899
TSHZ2 teashirt zinc finger homeobox 2 2.28375
H2BC17 H2B clustered histone 17 2.28355
IRGQ immunity-related GTPase family, Q 2.28352
CSPP1 centrosome and spindle pole associated protein 1 2.28095
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 2.2746
STIMATE STIM activating enhancer 2.27445
HIGD1B HIG1 hypoxia inducible domain family, member 1B 2.2735
RTCA RNA 3'-terminal phosphate cyclase 2.2724
CAPN9 calpain 9 2.27133
EFCC1 EF-hand and coiled-coil domain containing 1 2.2662
RAI14 retinoic acid induced 14 2.26485
GRK3 G protein-coupled receptor kinase 3 2.26477
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 2.2599
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.25975
DGKE diacylglycerol kinase, epsilon 64kDa 2.25835
ZFP2 ZFP2 zinc finger protein 2.2559
DCSTAMP dendrocyte expressed seven transmembrane protein 2.25555
ZNF804A zinc finger protein 804A 2.25385
ZNF362 zinc finger protein 362 2.2538
IFNW1 interferon, omega 1 2.2531
IL18RAP interleukin 18 receptor accessory protein 2.25255
CRYGB crystallin, gamma B 2.25135
ZW10 zw10 kinetochore protein 2.2494
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.24865
ARHGAP25 Rho GTPase activating protein 25 2.248
BICD1 bicaudal D homolog 1 (Drosophila) 2.24487
PLA2G1B phospholipase A2, group IB (pancreas) 2.2433
TMOD2 tropomodulin 2 (neuronal) 2.24045
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 2.23945
CA4 carbonic anhydrase IV 2.23758
ENC1 ectodermal-neural cortex 1 (with BTB domain) 2.23553
TM9SF3 transmembrane 9 superfamily member 3 2.23345
ATF3 activating transcription factor 3 2.2316
SLCO3A1 solute carrier organic anion transporter family, member 3A1 2.23135
FAM131B family with sequence similarity 131, member B 2.23075
EDNRA endothelin receptor type A 2.2299
RAB27B RAB27B, member RAS oncogene family 2.22972
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 2.22845
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 2.2265
GP6 glycoprotein VI (platelet) 2.22595
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.2254
CA7 carbonic anhydrase VII 2.22345
PHACTR1 phosphatase and actin regulator 1 2.21995
TM6SF1 transmembrane 6 superfamily member 1 2.21675
LOC100652777 group 10 secretory phospholipase A2-like 2.21465
SPIN2A spindlin family, member 2A 2.2125
EMC3 ER membrane protein complex subunit 3 2.20815
HBEGF heparin-binding EGF-like growth factor 2.20682
TRIM49D2 tripartite motif containing 49D2 2.2054
TRIM36 tripartite motif containing 36 2.20475
KLRC1 killer cell lectin-like receptor subfamily C, member 1 2.2032
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 2.20272
SYN3 synapsin III 2.20125
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 2.2002
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 2.19745
PRDM9 PR domain containing 9 2.1933
ANO2 anoctamin 2, calcium activated chloride channel 2.1932
TDP2 tyrosyl-DNA phosphodiesterase 2 2.19065
EIF5A2 eukaryotic translation initiation factor 5A2 2.1906
AKAP5 A kinase (PRKA) anchor protein 5 2.1876
SRFBP1 serum response factor binding protein 1 2.18485
CORO2B coronin, actin binding protein, 2B 2.18185
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.18075
PHEX phosphate regulating endopeptidase homolog, X-linked 2.1784
IPO13 importin 13 2.1754
FSCN2 fascin actin-bundling protein 2, retinal 2.1742
RASL10A RAS-like, family 10, member A 2.1729
RAP1GAP RAP1 GTPase activating protein 2.17095
ENTREP2 endosomal transmembrane epsin interactor 2 2.1647
ZNF493 zinc finger protein 493 2.164
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.1626
GK2 glycerol kinase 2 2.1619
CD177 CD177 molecule 2.15995
IGFBP3 insulin-like growth factor binding protein 3 2.15937
CSRNP3 cysteine-serine-rich nuclear protein 3 2.1581
DRD1 dopamine receptor D1 2.15685
TAS2R4 taste receptor, type 2, member 4 2.15645
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 2.15585
TPSAB1 tryptase alpha/beta 1 2.15572
IL2 interleukin 2 2.1551
EXO5 exonuclease 5 2.15365
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 2.1528
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 2.1514
OR7A10 olfactory receptor, family 7, subfamily A, member 10 2.1472
PTGDR2 prostaglandin D2 receptor 2 2.14647
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2.14615
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 2.14455
MBTD1 mbt domain containing 1 2.1411
LINC02854 long intergenic non-protein coding RNA 2854 2.1399
NEUROD1 neuronal differentiation 1 2.1377
STK10 serine/threonine kinase 10 2.13745
CD22 CD22 molecule 2.13595
A2M alpha-2-macroglobulin 2.13575
SLC25A30 solute carrier family 25, member 30 2.13355
TEX12 testis expressed 12 2.13345
IFT54 intraflagellar transport 54 2.13295
IL10RA interleukin 10 receptor, alpha 2.13275
DOCK5 dedicator of cytokinesis 5 2.13265
SNTG1 syntrophin, gamma 1 2.13175
LRRTM2 leucine rich repeat transmembrane neuronal 2 2.1314
CD160 CD160 molecule 2.1274
TMCO1 transmembrane and coiled-coil domains 1 2.1265
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.12645
KATNIP katanin interacting protein 2.12555
C2CD2 C2 calcium-dependent domain containing 2 2.1246
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 2.12445
IL3 interleukin 3 2.12315
ZNF835 zinc finger protein 835 2.1219
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.11817
PRDM10 PR domain containing 10 2.1181
PLPPR1 phospholipid phosphatase related 1 2.11625
FGR FGR proto-oncogene, Src family tyrosine kinase 2.1123
PKD2L2 polycystic kidney disease 2-like 2 2.1119
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 2.1075
SCARF1 scavenger receptor class F, member 1 2.10545
ARL15 ADP-ribosylation factor-like 15 2.10395
BCL2A1 BCL2-related protein A1 2.1031
TP53I3 tumor protein p53 inducible protein 3 2.10305
FGF20 fibroblast growth factor 20 2.1024
TSPAN2 tetraspanin 2 2.0999
ZNF442 zinc finger protein 442 2.09985
FEZF2 FEZ family zinc finger 2 2.0984
ZNF764 zinc finger protein 764 2.0973
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 2.09555
COL4A5 collagen, type IV, alpha 5 2.09545
PDLIM1 PDZ and LIM domain 1 2.0942
TEX14 testis expressed 14 2.09315
SH2B3 SH2B adaptor protein 3 2.0929
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 2.0918
PGAP3 post-GPI attachment to proteins 3 2.09028
RHD Rh blood group, D antigen 2.08935
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 2.0891
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2.08905
ZNF471 zinc finger protein 471 2.0886
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.08705
MAST3 microtubule associated serine/threonine kinase 3 2.08655
STARD8 StAR-related lipid transfer (START) domain containing 8 2.0843
AQP9 aquaporin 9 2.08425
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 2.0842
IAPP islet amyloid polypeptide 2.0818
KIAA0408 KIAA0408 2.0814
CELA2B chymotrypsin-like elastase family, member 2B 2.08125
IL1R1 interleukin 1 receptor, type I 2.0799
CLCA4 chloride channel accessory 4 2.07605
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.0756
ETHE1 ethylmalonic encephalopathy 1 2.07505
TRPC6 transient receptor potential cation channel, subfamily C, member 6 2.0747
RNF19B ring finger protein 19B 2.0746
ALAS1 5'-aminolevulinate synthase 1 2.0742
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 2.0722
ZNF682 zinc finger protein 682 2.07175
FRMPD4 FERM and PDZ domain containing 4 2.07105
GRB7 growth factor receptor-bound protein 7 2.0702
ZNF235 zinc finger protein 235 2.06895
ZNF10 zinc finger protein 10 2.06845
TAAR2 trace amine associated receptor 2 2.067
H3C7 H3 clustered histone 7 2.06645
ARHGAP22 Rho GTPase activating protein 22 2.0662
DAZL deleted in azoospermia-like 2.066
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 2.0645
IFNA16 interferon, alpha 16 2.06332
SEPTIN4 septin 4 2.0633
CPNE2 copine II 2.0625
ELMO1 engulfment and cell motility 1 2.0616
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.0615
OPRK1 opioid receptor, kappa 1 2.0614
CNKSR2 connector enhancer of kinase suppressor of Ras 2 2.0606
GPRIN2 G protein regulated inducer of neurite outgrowth 2 2.0603
TRHDE thyrotropin-releasing hormone degrading enzyme 2.0602
JPH3 junctophilin 3 2.0595
ARHGAP6 Rho GTPase activating protein 6 2.05875
EPHB1 EPH receptor B1 2.0584
TIMP2 TIMP metallopeptidase inhibitor 2 2.05815
MT1G metallothionein 1G 2.0578
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 2.05725
ARL4C ADP-ribosylation factor-like 4C 2.05722
PTPRD protein tyrosine phosphatase, receptor type, D 2.05707
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 2.05475
ZNF34 zinc finger protein 34 2.0546
ANKRD44 ankyrin repeat domain 44 2.0533
SDC2 syndecan 2 2.05038
SP4 Sp4 transcription factor 2.05025
CHD6 chromodomain helicase DNA binding protein 6 2.04878
SCTR secretin receptor 2.0481
ADGRE2 adhesion G protein-coupled receptor E2 2.048
IFNA5 interferon, alpha 5 2.04665
SUSD4 sushi domain containing 4 2.04475
PDE8B phosphodiesterase 8B 2.04465
ZNF780B zinc finger protein 780B 2.0398
SLC10A3 solute carrier family 10, member 3 2.0396
OR7C1 olfactory receptor, family 7, subfamily C, member 1 2.0381
H2BC14 H2B clustered histone 14 2.0377
SPICE1 spindle and centriole associated protein 1 2.0374
MAPK10 mitogen-activated protein kinase 10 2.0372
ZNF254 zinc finger protein 254 2.0366
DOCK4 dedicator of cytokinesis 4 2.03605
PEG10 paternally expressed 10 2.036
GAL3ST4 galactose-3-O-sulfotransferase 4 2.03555
PCDHB8 protocadherin beta 8 2.03515
PGM5 phosphoglucomutase 5 2.03505
IL10 interleukin 10 2.0347
TPO thyroid peroxidase 2.03255
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 2.03235
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 2.03195
BCO1 beta-carotene oxygenase 1 2.03035
KLHL18 kelch-like family member 18 2.03013
USP29 ubiquitin specific peptidase 29 2.0287
DGKI diacylglycerol kinase, iota 2.02855
SIPA1L3 signal-induced proliferation-associated 1 like 3 2.02807
BTC betacellulin 2.0258
FGF22 fibroblast growth factor 22 2.02575
VGLL1 vestigial-like family member 1 2.02548
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 2.02335
ZBED2 zinc finger, BED-type containing 2 2.02305
CASS4 Cas scaffolding protein family member 4 2.0219
KLRB1 killer cell lectin-like receptor subfamily B, member 1 2.02115
DGKB diacylglycerol kinase, beta 90kDa 2.01915
ETV3 ets variant 3 2.0175
CPA2 carboxypeptidase A2 (pancreatic) 2.01655
DIPK1A divergent protein kinase domain 1A 2.01468
GJA9 gap junction protein, alpha 9, 59kDa 2.0129
CIAO3 cytosolic iron-sulfur assembly component 3 2.01195
BMP8A bone morphogenetic protein 8a 2.01195
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.0103
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.00935
ADRA1B adrenoceptor alpha 1B 2.0092
RXRG retinoid X receptor, gamma 2.0086
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 2.00812
SLC7A4 solute carrier family 7, member 4 2.00625
DPP6 dipeptidyl-peptidase 6 2.00605
OSTM1 osteopetrosis associated transmembrane protein 1 2.0057

decreased expression

Symbol Name Standardized Value
UBE2C ubiquitin-conjugating enzyme E2C -9.85775
CDK1 cyclin-dependent kinase 1 -6.43467
TOP2A topoisomerase (DNA) II alpha 170kDa -6.3759
TXNDC9 thioredoxin domain containing 9 -6.19282
ADI1 acireductone dioxygenase 1 -5.3577
GALE UDP-galactose-4-epimerase -5.22725
PSRC1 proline/serine-rich coiled-coil 1 -4.9842
BAG3 BCL2-associated athanogene 3 -4.7101
ETFB electron-transfer-flavoprotein, beta polypeptide -4.7028
CD81 CD81 molecule -4.67975
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -4.627
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -4.4741
CCNB2 cyclin B2 -4.28455
NT5DC2 5'-nucleotidase domain containing 2 -4.0269
AURKB aurora kinase B -3.99815
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.9799
CCNA2 cyclin A2 -3.9619
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.88832
CARMIL1 capping protein regulator and myosin 1 linker 1 -3.88485
CDC25B cell division cycle 25B -3.7506
HMMR hyaluronan-mediated motility receptor (RHAMM) -3.74327
ZDHHC6 zinc finger, DHHC-type containing 6 -3.72585
MRPL12 mitochondrial ribosomal protein L12 -3.71285
ASF1B anti-silencing function 1B histone chaperone -3.6673
MRPS16 mitochondrial ribosomal protein S16 -3.642
CDK4 cyclin-dependent kinase 4 -3.63495
HADH hydroxyacyl-CoA dehydrogenase -3.63493
NUSAP1 nucleolar and spindle associated protein 1 -3.6242
PGM1 phosphoglucomutase 1 -3.5589
TP53 tumor protein p53 -3.50817
COG4 component of oligomeric golgi complex 4 -3.4925
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -3.4736
CDC20 cell division cycle 20 -3.4318
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -3.42335
OXA1L oxidase (cytochrome c) assembly 1-like -3.38335
RPA3 replication protein A3, 14kDa -3.36485
MELK maternal embryonic leucine zipper kinase -3.3296
SMC1A structural maintenance of chromosomes 1A -3.31228
KIF11 kinesin family member 11 -3.3121
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.29245
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -3.28485
TTK TTK protein kinase -3.19995
TES testin LIM domain protein -3.19
CETN3 centrin, EF-hand protein, 3 -3.10955
CBR3 carbonyl reductase 3 -3.00445
PLK1 polo-like kinase 1 -2.98715
RMI1 RecQ mediated genome instability 1 -2.97125
CENPA centromere protein A -2.96785
HOXA5 homeobox A5 -2.96315
NNT nicotinamide nucleotide transhydrogenase -2.94627
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -2.94025
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.93345
RUVBL1 RuvB-like AAA ATPase 1 -2.9205
NUP85 nucleoporin 85kDa -2.90125
STMN1 stathmin 1 -2.8867
CDCA4 cell division cycle associated 4 -2.8747
AKT1 v-akt murine thymoma viral oncogene homolog 1 -2.8542
CIRBP cold inducible RNA binding protein -2.84653
CKAP2 cytoskeleton associated protein 2 -2.8401
NCAPG2 non-SMC condensin II complex, subunit G2 -2.8385
SPAG7 sperm associated antigen 7 -2.82895
TPX2 TPX2, microtubule-associated -2.8061
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.79892
MSRB1 methionine sulfoxide reductase B1 -2.7743
KIF14 kinesin family member 14 -2.76885
BOLA1 bolA family member 1 -2.75625
RACGAP1 Rac GTPase activating protein 1 -2.7541
HJURP Holliday junction recognition protein -2.74675
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.74675
NLRP4 NLR family, pyrin domain containing 4 -2.74365
MKI67 marker of proliferation Ki-67 -2.70959
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 -2.7027
COX5B cytochrome c oxidase subunit Vb -2.6944
GAA glucosidase, alpha; acid -2.6793
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.6752
KIF20A kinesin family member 20A -2.6572
NMI N-myc (and STAT) interactor -2.6462
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.64575
PHGDH phosphoglycerate dehydrogenase -2.6418
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) -2.6411
TACC3 transforming, acidic coiled-coil containing protein 3 -2.62925
BIRC5 baculoviral IAP repeat containing 5 -2.6257
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.5984
DDIT4 DNA-damage-inducible transcript 4 -2.59495
FANCI Fanconi anemia, complementation group I -2.59328
PUM2 pumilio RNA-binding family member 2 -2.58068
ALDOC aldolase C, fructose-bisphosphate -2.54805
TPD52L1 tumor protein D52-like 1 -2.54572
BLM Bloom syndrome, RecQ helicase-like -2.5444
MZT2B mitotic spindle organizing protein 2B -2.5408
HAUS4 HAUS augmin-like complex, subunit 4 -2.53245
MRPL23 mitochondrial ribosomal protein L23 -2.53225
CCNF cyclin F -2.51552
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.48225
INTS3 integrator complex subunit 3 -2.47815
KIF15 kinesin family member 15 -2.4544
CDK6 cyclin-dependent kinase 6 -2.432
ZBED5 zinc finger, BED-type containing 5 -2.41685
SEPTIN6 septin 6 -2.40228
TROAP trophinin associated protein -2.39265
KRCC1 lysine-rich coiled-coil 1 -2.3853
SPDL1 spindle apparatus coiled-coil protein 1 -2.3825
FPGS folylpolyglutamate synthase -2.37775
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.37495
CDCA3 cell division cycle associated 3 -2.3682
CEP55 centrosomal protein 55kDa -2.36785
ATRAID all-trans retinoic acid-induced differentiation factor -2.353
TFDP1 transcription factor Dp-1 -2.34847
VRK1 vaccinia related kinase 1 -2.34465
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.33325
PPIE peptidylprolyl isomerase E (cyclophilin E) -2.33205
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.32435
FBXO5 F-box protein 5 -2.32125
NEIL3 nei endonuclease VIII-like 3 (E. coli) -2.3173
LOC112694756 uncharaterized LOC112694756 -2.316
MRPS2 mitochondrial ribosomal protein S2 -2.31465
IMMT inner membrane protein, mitochondrial -2.31005
KIF18A kinesin family member 18A -2.30785
UBA1 ubiquitin-like modifier activating enzyme 1 -2.29045
BAHCC1 BAH domain and coiled-coil containing 1 -2.2783
TRMT5 tRNA methyltransferase 5 -2.27805
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.25325
CHEK2 checkpoint kinase 2 -2.25325
PCNA proliferating cell nuclear antigen -2.25075
LYRM1 LYR motif containing 1 -2.2442
CDT1 chromatin licensing and DNA replication factor 1 -2.242
EAPP E2F-associated phosphoprotein -2.2406
HSPA1A heat shock 70kDa protein 1A -2.2371
ENO1 enolase 1, (alpha) -2.23685
AARS1 alanyl-tRNA synthetase 1 -2.23515
TRIM28 tripartite motif containing 28 -2.2244
ADNP activity-dependent neuroprotector homeobox -2.2203
ATP5F1D ATP synthase F1 subunit delta -2.21843
PPA2 pyrophosphatase (inorganic) 2 -2.21755
GYS1 glycogen synthase 1 (muscle) -2.2169
NCAPH non-SMC condensin I complex, subunit H -2.211
SNX17 sorting nexin 17 -2.21085
CLTA clathrin, light chain A -2.20658
GRB14 growth factor receptor-bound protein 14 -2.20615
UNC50 unc-50 homolog (C. elegans) -2.201
ACOD1 aconitate decarboxylase 1 -2.20025
TSKU tsukushi, small leucine rich proteoglycan -2.19925
POLE polymerase (DNA directed), epsilon, catalytic subunit -2.19485
SCYL3 SCY1-like 3 (S. cerevisiae) -2.19182
TRAPPC12 trafficking protein particle complex 12 -2.19115
EP400 E1A binding protein p400 -2.18197
CRYL1 crystallin, lambda 1 -2.1811
TBC1D16 TBC1 domain family, member 16 -2.1804
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.17623
IGFLR1 IGF-like family receptor 1 -2.1739
VAMP5 vesicle-associated membrane protein 5 -2.16285
NUP43 nucleoporin 43kDa -2.15715
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.15615
FKBP3 FK506 binding protein 3, 25kDa -2.15135
WASHC4 WASH complex subunit 4 -2.14903
EML4 echinoderm microtubule associated protein like 4 -2.14755
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.1464
MAGED1 melanoma antigen family D1 -2.14415
LACTB2 lactamase, beta 2 -2.1438
EXOC1 exocyst complex component 1 -2.13985
DDB2 damage-specific DNA binding protein 2, 48kDa -2.1354
DOCK1 dedicator of cytokinesis 1 -2.12845
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 -2.12455
MID1IP1 MID1 interacting protein 1 -2.1212
DCLRE1A DNA cross-link repair 1A -2.12085
SGSH N-sulfoglucosamine sulfohydrolase -2.11595
PTBP1 polypyrimidine tract binding protein 1 -2.11419
PRC1 protein regulator of cytokinesis 1 -2.11185
ECH1 enoyl CoA hydratase 1, peroxisomal -2.10635
MTA1 metastasis associated 1 -2.1009
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.09505
SETD1B SET domain containing 1B -2.0859
LBR lamin B receptor -2.08455
AMDHD2 amidohydrolase domain containing 2 -2.08415
FAM168B family with sequence similarity 168, member B -2.08185
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) -2.0767
CRTAP cartilage associated protein -2.07535
SIAH2 siah E3 ubiquitin protein ligase 2 -2.07485
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.06555
ANAPC1 anaphase promoting complex subunit 1 -2.06275
FADD Fas (TNFRSF6)-associated via death domain -2.0573
PCCB propionyl CoA carboxylase, beta polypeptide -2.0517
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.04485
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.04475
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 -2.03823
TSC22D4 TSC22 domain family, member 4 -2.03655
KIF4A kinesin family member 4A -2.02475
HMGB2 high mobility group box 2 -2.02225
PCYOX1L prenylcysteine oxidase 1 like -2.01505
SPC25 SPC25, NDC80 kinetochore complex component -2.01255
DARS1 aspartyl-tRNA synthetase 1 -2.00863
TIA1 TIA1 cytotoxic granule-associated RNA binding protein -2.00561
HNRNPF heterogeneous nuclear ribonucleoprotein F -2.0042
PHKA1 phosphorylase kinase, alpha 1 (muscle) -2.00245
GPSM2 G-protein signaling modulator 2 -2.00195