| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | griseofulvin 11.17 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
99 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:N12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | 6.72948 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 5.6506 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 5.00795 |
| COL11A1 | collagen, type XI, alpha 1 | 3.50163 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 3.1854 |
| TRAM2 | translocation associated membrane protein 2 | 3.0737 |
| EFHC1 | EF-hand domain (C-terminal) containing 1 | 3.0625 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 3.00685 |
| PLS1 | plastin 1 | 2.901 |
| WDR7 | WD repeat domain 7 | 2.5566 |
| CHN1 | chimerin 1 | 2.49975 |
| EMP2 | epithelial membrane protein 2 | 2.4599 |
| SMIM40 | small integral membrane protein 40 | 2.4328 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.40568 |
| NME5 | NME/NM23 family member 5 | 2.40465 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 | 2.397 |
| ADRB2 | adrenoceptor beta 2, surface | 2.39335 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 2.3498 |
| CD83 | CD83 molecule | 2.3431 |
| GET1 | guided entry of tail-anchored proteins factor 1 | 2.34085 |
| PSME3IP1 | proteasome activator subunit 3 interacting protein 1 | 2.3257 |
| PLAAT2 | phospholipase A and acyltransferase 2 | 2.3043 |
| ANKRD55 | ankyrin repeat domain 55 | 2.29815 |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 2.2871 |
| TBC1D31 | TBC1 domain family, member 31 | 2.27285 |
| ZNF33B | zinc finger protein 33B | 2.24585 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 2.2431 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 2.2079 |
| CETN2 | centrin, EF-hand protein, 2 | 2.2061 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.20315 |
| LOC105379278 | uncharacterized LOC105379278 | 2.1932 |
| TBPL1 | TBP-like 1 | 2.1763 |
| GHR | growth hormone receptor | 2.12655 |
| MTRF1 | mitochondrial translational release factor 1 | 2.118 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A | 2.0973 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 2.0809 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 2.07135 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 2.0683 |
| GUCY1B1 | guanylate cyclase 1 soluble subunit beta 1 | 2.05845 |
| ACYP2 | acylphosphatase 2, muscle type | 2.03235 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 2.0316 |
| WHR1 | winged helix repair factor 1 | 2.02922 |
| CCDC102B | coiled-coil domain containing 102B | 2.02515 |
| MNS1 | meiosis-specific nuclear structural 1 | 2.02195 |
| TCTN1 | tectonic family member 1 | 2.00825 |
| ZNF34 | zinc finger protein 34 | 2.0074 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 | 2.0008 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD320 | CD320 molecule | -9.93905 |
| HEATR1 | HEAT repeat containing 1 | -5.29947 |
| MSN | moesin | -5.17305 |
| KRT14 | keratin 14, type I | -5.0 |
| TUBA4A | tubulin, alpha 4a | -4.85835 |
| PCNA | proliferating cell nuclear antigen | -4.66275 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -4.55507 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -4.3256 |
| PFN1 | profilin 1 | -3.9478 |
| STXBP2 | syntaxin binding protein 2 | -3.85575 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -3.7876 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -3.56245 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -3.56085 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -3.4233 |
| GALE | UDP-galactose-4-epimerase | -3.1616 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | -2.94168 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.9154 |
| STK25 | serine/threonine kinase 25 | -2.88645 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.8807 |
| NOP56 | NOP56 ribonucleoprotein | -2.79767 |
| XPO7 | exportin 7 | -2.74178 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.6304 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -2.60385 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -2.56615 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -2.50778 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | -2.4812 |
| TIMM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) | -2.43432 |
| AMDHD2 | amidohydrolase domain containing 2 | -2.40275 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -2.39813 |
| PANK2 | pantothenate kinase 2 | -2.38845 |
| CHERP | calcium homeostasis endoplasmic reticulum protein | -2.3055 |
| ANKRD40 | ankyrin repeat domain 40 | -2.21615 |
| UQCR10 | ubiquinol-cytochrome c reductase, complex III subunit X | -2.17185 |
| ZNF358 | zinc finger protein 358 | -2.17015 |
| PTDSS2 | phosphatidylserine synthase 2 | -2.1613 |
| DDRGK1 | DDRGK domain containing 1 | -2.1608 |
| AURKB | aurora kinase B | -2.15235 |
| GSTP1 | glutathione S-transferase pi 1 | -2.1222 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -2.1221 |
| BAD | BCL2-associated agonist of cell death | -2.1212 |
| FAM174C | family with sequence similarity 174 member C | -2.11695 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -2.10145 |
| PFAS | phosphoribosylformylglycinamidine synthase | -2.1006 |
| JPT1 | Jupiter microtubule associated homolog 1 | -2.0939 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) | -2.0625 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit | -2.0427 |
| ITPA | inosine triphosphatase (nucleoside triphosphate pyrophosphatase) | -2.035 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) | -2.0301 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -2.0262 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -2.01835 |
| BSG | basigin (Ok blood group) | -2.01495 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -2.0035 |
