CRCGN017_MCF10A.WT.HP_24H:N13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description phenacetin 98.44 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

141 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:N13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 5.87015
GPER1 G protein-coupled estrogen receptor 1 5.76918
WIF1 WNT inhibitory factor 1 4.1314
ARID5B AT rich interactive domain 5B (MRF1-like) 3.89625
WASF3 WAS protein family, member 3 3.6276
TLR4 toll-like receptor 4 3.3437
LOC122526780 uncharacterized LOC122526780 3.26435
FCHO1 FCH domain only 1 3.0401
IL13 interleukin 13 2.90465
CTNND2 catenin (cadherin-associated protein), delta 2 2.84225
LRRN3 leucine rich repeat neuronal 3 2.77895
MACF1 microtubule-actin crosslinking factor 1 2.74061
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.72482
IL5 interleukin 5 2.69295
TRPV6 transient receptor potential cation channel, subfamily V, member 6 2.62415
GARRE1 granule associated Rac and RHOG effector 1 2.6019
PLPPR1 phospholipid phosphatase related 1 2.5608
FOXL2 forkhead box L2 2.5505
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.4992
KCNIP1 Kv channel interacting protein 1 2.49645
EVX1 even-skipped homeobox 1 2.4926
PHACTR4 phosphatase and actin regulator 4 2.48695
SLN sarcolipin 2.4583
MAOB monoamine oxidase B 2.4413
TRAPPC6A trafficking protein particle complex 6A 2.44045
ISOC1 isochorismatase domain containing 1 2.43765
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 2.4319
NAP1L3 nucleosome assembly protein 1-like 3 2.4222
ACTA1 actin, alpha 1, skeletal muscle 2.42005
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.41025
CCL3L3 chemokine (C-C motif) ligand 3-like 3 2.41005
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 2.3769
TMEM120B transmembrane protein 120B 2.3737
STAU2 staufen double-stranded RNA binding protein 2 2.3397
CUEDC1 CUE domain containing 1 2.3349
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 2.33468
IL17RB interleukin 17 receptor B 2.3235
DPP4 dipeptidyl-peptidase 4 2.32018
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 2.31645
PPP1R9A protein phosphatase 1, regulatory subunit 9A 2.30565
GFAP glial fibrillary acidic protein 2.28995
MYBPH myosin binding protein H 2.2677
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 2.251
ZIC1 Zic family member 1 2.2486
SOBP sine oculis binding protein homolog (Drosophila) 2.2193
AKAP8L A kinase (PRKA) anchor protein 8-like 2.19497
CCDC71 coiled-coil domain containing 71 2.1913
VRTN vertebrae development associated 2.1841
GRIA3 glutamate receptor, ionotropic, AMPA 3 2.183
SORCS3 sortilin-related VPS10 domain containing receptor 3 2.174
BAMBI BMP and activin membrane-bound inhibitor 2.14905
RASL11B RAS-like, family 11, member B 2.14545
AMHR2 anti-Mullerian hormone receptor, type II 2.1444
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.1366
TTYH1 tweety family member 1 2.13465
POLH polymerase (DNA directed), eta 2.13355
DPF1 D4, zinc and double PHD fingers family 1 2.12585
AGO2 argonaute RISC catalytic component 2 2.1223
SUGP2 SURP and G patch domain containing 2 2.12197
SCRG1 stimulator of chondrogenesis 1 2.1169
CA10 carbonic anhydrase X 2.1114
APOE apolipoprotein E 2.1071
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 2.10515
MTM1 myotubularin 1 2.10378
DPP6 dipeptidyl-peptidase 6 2.09915
TET3 tet methylcytosine dioxygenase 3 2.0928
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 2.08965
MDN1 MDN1, midasin homolog (yeast) 2.0813
SLC4A3 solute carrier family 4 (anion exchanger), member 3 2.08115
GPR19 G protein-coupled receptor 19 2.0792
KLHDC8A kelch domain containing 8A 2.06805
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 2.06305
HLA-DMB major histocompatibility complex, class II, DM beta 2.058
DOK5 docking protein 5 2.04935
PCDHGA8 protocadherin gamma subfamily A, 8 2.04845
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 2.04835
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 2.04795
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 2.04615
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.04535
MYOT myotilin 2.04255
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 2.0388
TERT telomerase reverse transcriptase 2.0381
RRAS2 related RAS viral (r-ras) oncogene homolog 2 2.0364
GPM6A glycoprotein M6A 2.03397
PCDHB12 protocadherin beta 12 2.02365
NCAN neurocan 2.02255
UNC13A unc-13 homolog A (C. elegans) 2.02245
ZNF671 zinc finger protein 671 2.01705
NOL9 nucleolar protein 9 2.01335
PODXL podocalyxin-like 2.01265
NNAT neuronatin 2.00675
OMG oligodendrocyte myelin glycoprotein 2.00505
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 2.0047

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.4759
TM9SF3 transmembrane 9 superfamily member 3 -4.75965
HACD3 3-hydroxyacyl-CoA dehydratase 3 -4.68255
YME1L1 YME1-like 1 ATPase -4.65512
CD81 CD81 molecule -3.92355
KRT14 keratin 14, type I -3.735
STXBP2 syntaxin binding protein 2 -3.63
COG4 component of oligomeric golgi complex 4 -3.39925
SNX7 sorting nexin 7 -3.3692
MSMO1 methylsterol monooxygenase 1 -3.26285
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.9822
RXYLT1 ribitol xylosyltransferase 1 -2.97067
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.91505
PLEK2 pleckstrin 2 -2.7983
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.77595
MTPAP mitochondrial poly(A) polymerase -2.7243
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -2.6576
MT2A metallothionein 2A -2.6532
DCTD dCMP deaminase -2.64647
RAB11A RAB11A, member RAS oncogene family -2.52623
TUBA4A tubulin, alpha 4a -2.39445
SLIT2 slit homolog 2 (Drosophila) -2.38105
SEPTIN10 septin 10 -2.3662
NGRN neugrin, neurite outgrowth associated -2.32825
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.32695
PTER phosphotriesterase related -2.29895
ZWILCH zwilch kinetochore protein -2.2228
PPCDC phosphopantothenoylcysteine decarboxylase -2.20235
RNPEP arginyl aminopeptidase (aminopeptidase B) -2.19535
GFPT1 glutamine--fructose-6-phosphate transaminase 1 -2.18158
PFN1 profilin 1 -2.16035
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.16025
PRPF18 pre-mRNA processing factor 18 -2.15445
CRTAP cartilage associated protein -2.1371
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -2.11595
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -2.1016
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -2.09935
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.0904
TENT5C terminal nucleotidyltransferase 5C -2.06355
RNF187 ring finger protein 187 -2.06195
TMED3 transmembrane emp24 protein transport domain containing 3 -2.04995
CD46 CD46 molecule, complement regulatory protein -2.04722
KIF5B kinesin family member 5B -2.0436
CTNND1 catenin (cadherin-associated protein), delta 1 -2.0434
S100A3 S100 calcium binding protein A3 -2.03245
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.02105
RAB13 RAB13, member RAS oncogene family -2.01265
NRN1 neuritin 1 -2.0025