| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | phenacetin 10.94 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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172 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:N15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 5.2285 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.0759 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | 5.0299 |
| IDE | insulin-degrading enzyme | 3.88195 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.1948 |
| BECN1 | beclin 1, autophagy related | 3.04705 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 3.0369 |
| RAB31 | RAB31, member RAS oncogene family | 2.927 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 2.915 |
| TRIM13 | tripartite motif containing 13 | 2.8225 |
| HBB | hemoglobin, beta | 2.78838 |
| FZD7 | frizzled class receptor 7 | 2.61913 |
| TRAPPC6A | trafficking protein particle complex 6A | 2.61305 |
| MTRF1 | mitochondrial translational release factor 1 | 2.51215 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) | 2.49885 |
| RAB27B | RAB27B, member RAS oncogene family | 2.46805 |
| ARL4A | ADP-ribosylation factor-like 4A | 2.46485 |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) | 2.45833 |
| GHR | growth hormone receptor | 2.45715 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 2.45385 |
| CCNA1 | cyclin A1 | 2.4417 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.42882 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 2.4279 |
| CCNB1 | cyclin B1 | 2.3818 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 2.35608 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 2.34575 |
| TRIM52 | tripartite motif containing 52 | 2.3449 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 2.34265 |
| CEP15 | centrosomal protein 15 | 2.3339 |
| TUBD1 | tubulin, delta 1 | 2.32597 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | 2.32263 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.27955 |
| EFHD1 | EF-hand domain family, member D1 | 2.27445 |
| DENND10 | DENN domain containing 10 | 2.26835 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) | 2.2667 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 2.26292 |
| S100A7 | S100 calcium binding protein A7 | 2.2441 |
| TDRD3 | tudor domain containing 3 | 2.22458 |
| TMEM254 | transmembrane protein 254 | 2.21095 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 2.20945 |
| MFF | mitochondrial fission factor | 2.2031 |
| EPHA4 | EPH receptor A4 | 2.19905 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like | 2.19495 |
| LARS1 | leucyl-tRNA synthetase 1 | 2.19055 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 2.1868 |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 | 2.18255 |
| PYROXD1 | pyridine nucleotide-disulphide oxidoreductase domain 1 | 2.16445 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) | 2.1581 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 | 2.157 |
| HAT1 | histone acetyltransferase 1 | 2.15695 |
| RIPPLY2-CYB5R4 | RIPPLY2-CYB5R4 readthrough | 2.1494 |
| FLG | filaggrin | 2.14725 |
| JAK2 | Janus kinase 2 | 2.13985 |
| TSTD2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | 2.1264 |
| RIDA | reactive intermediate imine deaminase A homolog | 2.1214 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | 2.10825 |
| CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2.09525 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 2.0863 |
| ERLIN2 | ER lipid raft associated 2 | 2.08418 |
| LIN7B | lin-7 homolog B (C. elegans) | 2.083 |
| HBA1 | hemoglobin, alpha 1 | 2.07703 |
| COL5A2 | collagen, type V, alpha 2 | 2.07687 |
| LYRM2 | LYR motif containing 2 | 2.07595 |
| LORICRIN | loricrin cornified envelope precursor protein | 2.0753 |
| COL6A3 | collagen, type VI, alpha 3 | 2.06805 |
| OCA2 | oculocutaneous albinism II | 2.0668 |
| KRT2 | keratin 2, type II | 2.06615 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | 2.062 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 2.05935 |
| EPHX3 | epoxide hydrolase 3 | 2.0587 |
| LARP7 | La ribonucleoprotein domain family, member 7 | 2.0572 |
| LYRM1 | LYR motif containing 1 | 2.05435 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) | 2.04457 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 | 2.04405 |
| DMXL1 | Dmx-like 1 | 2.0436 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 2.04305 |
| GSTK1 | glutathione S-transferase kappa 1 | 2.0314 |
| CETN2 | centrin, EF-hand protein, 2 | 2.02895 |
| MPC2 | mitochondrial pyruvate carrier 2 | 2.02715 |
| IL15 | interleukin 15 | 2.02705 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 | 2.02597 |
| TSC1 | tuberous sclerosis 1 | 2.01765 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 2.01325 |
| LIFR | leukemia inhibitory factor receptor alpha | 2.01295 |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein | 2.011 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 | 2.00675 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EXOSC4 | exosome component 4 | -7.50267 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -6.61585 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | -5.33135 |
| CCDC86 | coiled-coil domain containing 86 | -5.1932 |
| TUBA4A | tubulin, alpha 4a | -5.0 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | -4.93585 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -4.9025 |
| ACOT9 | acyl-CoA thioesterase 9 | -4.71565 |
| PCNA | proliferating cell nuclear antigen | -4.39205 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.25105 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.8674 |
| PLK1 | polo-like kinase 1 | -3.84885 |
| TLCD3A | TLC domain containing 3A | -3.81165 |
| PLOD3 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 | -3.7515 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | -3.69285 |
| KRT14 | keratin 14, type I | -3.6082 |
| STXBP2 | syntaxin binding protein 2 | -3.5791 |
| MSN | moesin | -3.5733 |
| GFUS | GDP-L-fucose synthase | -3.5636 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -3.45427 |
| CDC20 | cell division cycle 20 | -3.34075 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -3.28638 |
| MCOLN1 | mucolipin 1 | -3.1426 |
| NUDC | nudC nuclear distribution protein | -3.12715 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -3.03845 |
| MT2A | metallothionein 2A | -2.9526 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 | -2.9501 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -2.93005 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -2.9237 |
| FPGS | folylpolyglutamate synthase | -2.8443 |
| AMDHD2 | amidohydrolase domain containing 2 | -2.82555 |
| MTA1 | metastasis associated 1 | -2.74633 |
| NISCH | nischarin | -2.72915 |
| PNKP | polynucleotide kinase 3'-phosphatase | -2.69095 |
| OSBPL10 | oxysterol binding protein-like 10 | -2.6486 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -2.64575 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -2.64045 |
| PNPLA6 | patatin-like phospholipase domain containing 6 | -2.5421 |
| KIF2C | kinesin family member 2C | -2.5364 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -2.526 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -2.5248 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -2.50925 |
| AXIN1 | axin 1 | -2.50495 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -2.4537 |
| MGAT4B | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B | -2.45205 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -2.37675 |
| DBN1 | drebrin 1 | -2.3576 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -2.3568 |
| TIMM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) | -2.33502 |
| SNX7 | sorting nexin 7 | -2.3251 |
| NIPSNAP1 | nipsnap homolog 1 (C. elegans) | -2.32387 |
| MVP | major vault protein | -2.31375 |
| ANKRD10 | ankyrin repeat domain 10 | -2.31025 |
| SMTN | smoothelin | -2.30687 |
| FOXK2 | forkhead box K2 | -2.27415 |
| SORBS3 | sorbin and SH3 domain containing 3 | -2.2727 |
| PRMT5 | protein arginine methyltransferase 5 | -2.25665 |
| KLC1 | kinesin light chain 1 | -2.24787 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | -2.24295 |
| MRPL30 | mitochondrial ribosomal protein L30 | -2.22265 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.21618 |
| CARM1 | coactivator-associated arginine methyltransferase 1 | -2.21035 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | -2.20475 |
| PANK4 | pantothenate kinase 4 | -2.2029 |
| FOSL1 | FOS-like antigen 1 | -2.19625 |
| LOC112694756 | uncharaterized LOC112694756 | -2.19127 |
| SAC3D1 | SAC3 domain containing 1 | -2.1891 |
| VAT1 | vesicle amine transport 1 | -2.15575 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.1468 |
| TWF2 | twinfilin actin binding protein 2 | -2.1262 |
| TNIP1 | TNFAIP3 interacting protein 1 | -2.1188 |
| ILK | integrin-linked kinase | -2.11305 |
| MAP1S | microtubule-associated protein 1S | -2.109 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 | -2.10415 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) | -2.0879 |
| PRKCD | protein kinase C, delta | -2.08715 |
| MNT | MAX network transcriptional repressor | -2.0805 |
| RIC8A | RIC8 guanine nucleotide exchange factor A | -2.0755 |
| DUSP4 | dual specificity phosphatase 4 | -2.06087 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.0535 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 | -2.0401 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -2.03695 |
| MRPL37 | mitochondrial ribosomal protein L37 | -2.024 |
| CDR2L | cerebellar degeneration-related protein 2-like | -2.02235 |
| COG4 | component of oligomeric golgi complex 4 | -2.016 |
| IER3 | immediate early response 3 | -2.01175 |
