CRCGN017_MCF10A.WT.HP_24H:N19 Gene Set
Dataset
Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category
transcriptomics
Type
small molecule perturbation
Description
trisodium 5-oxo-1-(4-sulfonatophenyl)-4-[(e)-(4-sulfonatophenyl)diazenyl]-2,5-dihydro-1h-pyrazole-3-carboxylate 100.87 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome )
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Genes
29 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:N19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
Symbol
Name
Standardized Value
ABHD4
abhydrolase domain containing 4
4.6942
SPAG4
sperm associated antigen 4
4.4814
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
4.47965
ACAA1
acetyl-CoA acyltransferase 1
3.10155
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
3.0915
CCL2
chemokine (C-C motif) ligand 2
2.9717
TCTN1
tectonic family member 1
2.46135
SLC5A6
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
2.35775
FCHO1
FCH domain only 1
2.20325
SESN1
sestrin 1
2.18865
ZMIZ1
zinc finger, MIZ-type containing 1
2.1461
NAP1L2
nucleosome assembly protein 1-like 2
2.13605
EVI2B
ecotropic viral integration site 2B
2.1201
CYCS
cytochrome c, somatic
2.0753
GTPBP8
GTP-binding protein 8 (putative)
2.01835
decreased expression
Symbol
Name
Standardized Value
RXYLT1
ribitol xylosyltransferase 1
-3.74463
VDAC1
voltage-dependent anion channel 1
-3.5066
ARPP19
cAMP-regulated phosphoprotein, 19kDa
-3.25637
STXBP2
syntaxin binding protein 2
-3.15005
NGRN
neugrin, neurite outgrowth associated
-2.94915
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
-2.83145
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
-2.48825
TLCD3A
TLC domain containing 3A
-2.4872
DNAJA3
DnaJ (Hsp40) homolog, subfamily A, member 3
-2.41185
RPS5
ribosomal protein S5
-2.36655
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
-2.31523
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
-2.11762
CARMIL1
capping protein regulator and myosin 1 linker 1
-2.10575
CORO1A
coronin, actin binding protein, 1A
-2.08035
