CRCGN017_MCF10A.WT.HP_24H:N20 Gene Set
Dataset
Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category
transcriptomics
Type
small molecule perturbation
Description
trisodium 5-oxo-1-(4-sulfonatophenyl)-4-[(e)-(4-sulfonatophenyl)diazenyl]-2,5-dihydro-1h-pyrazole-3-carboxylate 33.62 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome )
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Genes
24 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:N20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
Symbol
Name
Standardized Value
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
5.19085
ACAA1
acetyl-CoA acyltransferase 1
3.3595
ARID5B
AT rich interactive domain 5B (MRF1-like)
3.3307
PDLIM1
PDZ and LIM domain 1
2.6099
SKIC8
SKI8 subunit of superkiller complex
2.3584
TRAPPC6A
trafficking protein particle complex 6A
2.24825
RFC5
replication factor C (activator 1) 5, 36.5kDa
2.17575
DUSP11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
2.16055
PCBP4
poly(rC) binding protein 4
2.08925
decreased expression
Symbol
Name
Standardized Value
MRPS2
mitochondrial ribosomal protein S2
-5.01735
SNX7
sorting nexin 7
-4.1896
PPP1R26
protein phosphatase 1, regulatory subunit 26
-3.96585
CD320
CD320 molecule
-3.01415
DNAJA3
DnaJ (Hsp40) homolog, subfamily A, member 3
-2.89095
SEC16A
SEC16 homolog A (S. cerevisiae)
-2.8022
ELAC2
elaC ribonuclease Z 2
-2.7699
SLC7A5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
-2.66255
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
-2.50268
PAEP
progestagen-associated endometrial protein
-2.433
MED22
mediator complex subunit 22
-2.33745
REXO4
REX4, RNA exonuclease 4 homolog (S. cerevisiae)
-2.27085
PRRC2B
proline-rich coiled-coil 2B
-2.19565
PFN1
profilin 1
-2.1034
SETX
senataxin
-2.04115
