CRCGN017_MCF10A.WT.HP_24H:O04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description UnTrt perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

483 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:O04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
WIF1 WNT inhibitory factor 1 6.40617
HBA1 hemoglobin, alpha 1 5.49545
MEF2C myocyte enhancer factor 2C 5.45021
CERK ceramide kinase 4.57331
HBB hemoglobin, beta 4.35286
DENND2D DENN/MADD domain containing 2D 3.99951
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.91667
KLHL21 kelch-like family member 21 3.64042
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 3.63246
MYL9 myosin, light chain 9, regulatory 3.62947
BAMBI BMP and activin membrane-bound inhibitor 3.4426
ABHD4 abhydrolase domain containing 4 3.34966
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 3.22759
CD200 CD200 molecule 3.16632
GPR19 G protein-coupled receptor 19 3.05136
RSF1 remodeling and spacing factor 1 3.04639
TRAPPC6A trafficking protein particle complex 6A 3.04125
NIPSNAP3B nipsnap homolog 3B (C. elegans) 3.01789
FPGT fucose-1-phosphate guanylyltransferase 3.0129
NOD2 nucleotide-binding oligomerization domain containing 2 2.98667
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 2.96354
ATRNL1 attractin-like 1 2.95157
RASL11B RAS-like, family 11, member B 2.94179
JAK2 Janus kinase 2 2.89869
PLSCR1 phospholipid scramblase 1 2.86904
CXCR1 chemokine (C-X-C motif) receptor 1 2.85285
COL11A1 collagen, type XI, alpha 1 2.82728
DACT1 dishevelled-binding antagonist of beta-catenin 1 2.7645
RAB6B RAB6B, member RAS oncogene family 2.74915
GRM6 glutamate receptor, metabotropic 6 2.73929
AOAH acyloxyacyl hydrolase (neutrophil) 2.73406
ZNF141 zinc finger protein 141 2.71513
FGFR3 fibroblast growth factor receptor 3 2.71486
PLPP6 phospholipid phosphatase 6 2.71341
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 2.69174
ADGRE3 adhesion G protein-coupled receptor E3 2.68355
NANOS3 nanos homolog 3 (Drosophila) 2.67211
FAM204A family with sequence similarity 204, member A 2.66519
DDN dendrin 2.66232
EDN1 endothelin 1 2.65718
ARB2A ARB2 cotranscriptional regulator A 2.65518
RTN2 reticulon 2 2.63938
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 2.63784
DEPTOR DEP domain containing MTOR-interacting protein 2.63103
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 2.60586
FAM50B family with sequence similarity 50, member B 2.60403
TLR1 toll-like receptor 1 2.60227
IGSF6 immunoglobulin superfamily, member 6 2.58436
POLD3 polymerase (DNA-directed), delta 3, accessory subunit 2.5701
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 2.5685
SOX2 SRY (sex determining region Y)-box 2 2.56272
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.55876
TRIM66 tripartite motif containing 66 2.55787
SH3GL3 SH3-domain GRB2-like 3 2.55382
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 2.55213
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 2.55084
RNF13 ring finger protein 13 2.54396
STRN striatin, calmodulin binding protein 2.53917
KIAA0319 KIAA0319 2.53849
RBM41 RNA binding motif protein 41 2.53839
DOK5 docking protein 5 2.53483
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 2.53127
TM6SF1 transmembrane 6 superfamily member 1 2.52412
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.52344
AADAC arylacetamide deacetylase 2.51906
CFHR2 complement factor H-related 2 2.51858
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 2.51544
ZNF586 zinc finger protein 586 2.51444
YPEL5 yippee-like 5 (Drosophila) 2.51435
ZNF548 zinc finger protein 548 2.51077
KIF5A kinesin family member 5A 2.508
WASHC5 WASH complex subunit 5 2.50449
RAB21 RAB21, member RAS oncogene family 2.50026
ZNF124 zinc finger protein 124 2.49424
CNKSR2 connector enhancer of kinase suppressor of Ras 2 2.48776
PYHIN1 pyrin and HIN domain family, member 1 2.48407
IL12RB2 interleukin 12 receptor, beta 2 2.47541
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2.46508
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 2.45593
PILRA paired immunoglobin-like type 2 receptor alpha 2.45299
THSD4 thrombospondin, type I, domain containing 4 2.44881
ZNF835 zinc finger protein 835 2.44569
SYN2 synapsin II 2.44508
ZNF318 zinc finger protein 318 2.43854
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 2.43356
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 2.43268
FAM76A family with sequence similarity 76, member A 2.43073
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 2.42728
CD86 CD86 molecule 2.42698
TRIM52 tripartite motif containing 52 2.42584
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 2.4258
FBXO3 F-box protein 3 2.42548
TLR8 toll-like receptor 8 2.42505
SCN3B sodium channel, voltage gated, type III beta subunit 2.42471
TBR1 T-box, brain, 1 2.41682
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 2.416
CLEC10A C-type lectin domain family 10, member A 2.41568
SYN3 synapsin III 2.41249
MOB3B MOB kinase activator 3B 2.40982
ZFPM2 zinc finger protein, FOG family member 2 2.40827
ZNF253 zinc finger protein 253 2.4
TMEM94 transmembrane protein 94 2.39976
MMP2 matrix metallopeptidase 2 2.39687
MYOZ3 myozenin 3 2.39606
ARID3A AT rich interactive domain 3A (BRIGHT-like) 2.39399
MYOM2 myomesin 2 2.39368
CRIPTO3 cripto, EGF-CFC family member 3 2.39342
ADAM21 ADAM metallopeptidase domain 21 2.38903
RNF39 ring finger protein 39 2.38575
PPEF1 protein phosphatase, EF-hand calcium binding domain 1 2.38389
SP4 Sp4 transcription factor 2.38354
TERT telomerase reverse transcriptase 2.38032
CNTN5 contactin 5 2.37876
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 2.37828
CXCR4 chemokine (C-X-C motif) receptor 4 2.3715
ZNF507 zinc finger protein 507 2.3711
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 2.37048
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 2.3654
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa 2.36396
GHR growth hormone receptor 2.36134
CHRM3 cholinergic receptor, muscarinic 3 2.35573
H2AJ H2A.J histone 2.35431
NGRN neugrin, neurite outgrowth associated 2.35421
OR10J1 olfactory receptor, family 10, subfamily J, member 1 2.35128
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 2.3511
AK5 adenylate kinase 5 2.34758
HOXA2 homeobox A2 2.34634
GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 2.34367
GSDMB gasdermin B 2.34257
YIPF1 Yip1 domain family, member 1 2.33875
PPP1R17 protein phosphatase 1, regulatory subunit 17 2.33702
TUBB4A tubulin, beta 4A class IVa 2.33621
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 2.33477
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 2.33396
ZBTB44 zinc finger and BTB domain containing 44 2.33035
ART3 ADP-ribosyltransferase 3 2.32934
SUMO4 small ubiquitin-like modifier 4 2.3288
EPHB1 EPH receptor B1 2.32752
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.32233
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 2.32189
IKZF2 IKAROS family zinc finger 2 (Helios) 2.32087
TRIM5 tripartite motif containing 5 2.31991
STARD5 StAR-related lipid transfer (START) domain containing 5 2.3199
ISYNA1 inositol-3-phosphate synthase 1 2.31634
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.31371
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 2.3126
MIMS2 mitochondrial inner membrane scaffold 2 2.31056
SLC30A3 solute carrier family 30 (zinc transporter), member 3 2.30327
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 2.30232
FGR FGR proto-oncogene, Src family tyrosine kinase 2.30206
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 2.30182
FRMPD4 FERM and PDZ domain containing 4 2.30165
HOXD1 homeobox D1 2.29855
NCAN neurocan 2.29756
ENGASE endo-beta-N-acetylglucosaminidase 2.2975
PCLO piccolo presynaptic cytomatrix protein 2.29272
BCO1 beta-carotene oxygenase 1 2.28968
OR5I1 olfactory receptor, family 5, subfamily I, member 1 2.2842
KRT23 keratin 23, type I 2.28403
ADA2 adenosine deaminase 2 2.28272
BCL2L14 BCL2-like 14 (apoptosis facilitator) 2.27625
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 2.27477
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 2.27014
BTBD8 BTB (POZ) domain containing 8 2.26499
RRH retinal pigment epithelium-derived rhodopsin homolog 2.26386
CSH2 chorionic somatomammotropin hormone 2 2.26271
TMEM143 transmembrane protein 143 2.26254
ITFG1 integrin alpha FG-GAP repeat containing 1 2.26138
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.25546
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 2.25442
COL4A4 collagen, type IV, alpha 4 2.25212
PID1 phosphotyrosine interaction domain containing 1 2.24981
FAM131A family with sequence similarity 131, member A 2.24704
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 2.24595
NUAK1 NUAK family, SNF1-like kinase, 1 2.24227
ELAVL2 ELAV like neuron-specific RNA binding protein 2 2.2412
TNIP3 TNFAIP3 interacting protein 3 2.241
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 2.23987
ARL15 ADP-ribosylation factor-like 15 2.23973
CFHR5 complement factor H-related 5 2.2397
CD300A CD300a molecule 2.23696
LOC100996709 ADP-ribosylation factor-like protein 17 2.23663
ZNF606 zinc finger protein 606 2.23601
DRP2 dystrophin related protein 2 2.23594
ZNF107 zinc finger protein 107 2.23564
CD226 CD226 molecule 2.23448
SPAST spastin 2.23399
TAS2R1 taste receptor, type 2, member 1 2.22963
PRR14L proline rich 14-like 2.22652
REG1B regenerating islet-derived 1 beta 2.22579
PEX5L peroxisomal biogenesis factor 5-like 2.22216
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.22079
ZNF235 zinc finger protein 235 2.21985
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 2.2198
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B 2.21843
FGFR2 fibroblast growth factor receptor 2 2.2182
EEF1AKMT3 EEF1A lysine methyltransferase 3 2.21748
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6 2.21699
SEC31B SEC31 homolog B (S. cerevisiae) 2.21582
MSTN myostatin 2.21488
ZBTB3 zinc finger and BTB domain containing 3 2.20851
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.20734
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 2.20705
PSG5 pregnancy specific beta-1-glycoprotein 5 2.20267
MGAM2 maltase-glucoamylase 2 (putative) 2.1985
CABP1 calcium binding protein 1 2.1971
VEGFD vascular endothelial growth factor D 2.19628
FPR2 formyl peptide receptor 2 2.19536
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.19244
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 2.19218
OLFML1 olfactomedin-like 1 2.19087
ZNF514 zinc finger protein 514 2.19073
RTP4 receptor (chemosensory) transporter protein 4 2.1898
ZNF492 zinc finger protein 492 2.18802
PPCS phosphopantothenoylcysteine synthetase 2.18695
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like 2.18489
ACKR3 atypical chemokine receptor 3 2.18485
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 2.18341
QSER1 glutamine and serine rich 1 2.18312
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 2.1816
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 2.18145
RNF44 ring finger protein 44 2.18137
CPA4 carboxypeptidase A4 2.18116
ACVR2B activin A receptor, type IIB 2.17923
CA5B carbonic anhydrase VB, mitochondrial 2.17883
FOS FBJ murine osteosarcoma viral oncogene homolog 2.17792
CASP1 caspase 1, apoptosis-related cysteine peptidase 2.17791
HLA-DRA major histocompatibility complex, class II, DR alpha 2.17731
MSX2 msh homeobox 2 2.17597
MAN2C1 mannosidase, alpha, class 2C, member 1 2.17578
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 2.17359
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 2.17264
IL20RA interleukin 20 receptor, alpha 2.17075
CCL3L3 chemokine (C-C motif) ligand 3-like 3 2.16925
NUP62CL nucleoporin 62kDa C-terminal like 2.16801
WDR7 WD repeat domain 7 2.16697
RIMS1 regulating synaptic membrane exocytosis 1 2.16407
LRRC31 leucine rich repeat containing 31 2.16346
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 2.16223
LIAS lipoic acid synthetase 2.15857
CLEC4E C-type lectin domain family 4, member E 2.15816
TBC1D15 TBC1 domain family, member 15 2.15774
NLK nemo-like kinase 2.15544
RFX4 regulatory factor X, 4 (influences HLA class II expression) 2.15429
EGF epidermal growth factor 2.15366
ELMO1 engulfment and cell motility 1 2.15231
DRD5 dopamine receptor D5 2.15011
HIGD1B HIG1 hypoxia inducible domain family, member 1B 2.14995
ZNF223 zinc finger protein 223 2.14775
MYO16 myosin XVI 2.14737
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 2.14658
SIGLEC6 sialic acid binding Ig-like lectin 6 2.14545
PECAM1 platelet/endothelial cell adhesion molecule 1 2.14135
IFNA16 interferon, alpha 16 2.13958
GIMAP6 GTPase, IMAP family member 6 2.13694
SLC35E2B solute carrier family 35, member E2B 2.13664
CLIP3 CAP-GLY domain containing linker protein 3 2.1345
MMUT methylmalonyl-CoA mutase 2.13403
DGKI diacylglycerol kinase, iota 2.13002
ZNF529 zinc finger protein 529 2.12939
PRDM10 PR domain containing 10 2.12798
SLAMF7 SLAM family member 7 2.12397
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 2.12326
N4BP2L1 NEDD4 binding protein 2-like 1 2.11903
NOTCH1 notch 1 2.11777
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 2.11703
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 2.11348
MTRF1 mitochondrial translational release factor 1 2.1115
FAN1 FANCD2/FANCI-associated nuclease 1 2.1078
AMPD1 adenosine monophosphate deaminase 1 2.10772
MED31 mediator complex subunit 31 2.1073
ERMAP erythroblast membrane-associated protein (Scianna blood group) 2.10586
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 2.10557
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 2.10483
EFHD1 EF-hand domain family, member D1 2.10473
TAC3 tachykinin 3 2.10417
GRM5 glutamate receptor, metabotropic 5 2.10279
PARPBP PARP1 binding protein 2.10197
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 2.10192
PSG2 pregnancy specific beta-1-glycoprotein 2 2.10031
MFF mitochondrial fission factor 2.1003
WNT2B wingless-type MMTV integration site family, member 2B 2.09944
PCDHGA9 protocadherin gamma subfamily A, 9 2.09809
SH2B2 SH2B adaptor protein 2 2.09714
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 2.09536
ADGRG3 adhesion G protein-coupled receptor G3 2.09523
MRPL44 mitochondrial ribosomal protein L44 2.09476
TAS2R4 taste receptor, type 2, member 4 2.09467
OBP2B odorant binding protein 2B 2.09197
CDH9 cadherin 9, type 2 (T1-cadherin) 2.09192
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 2.09122
DUSP28 dual specificity phosphatase 28 2.09005
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 2.08957
SCN10A sodium channel, voltage gated, type X alpha subunit 2.08693
RLN2 relaxin 2 2.08643
METRN meteorin, glial cell differentiation regulator 2.08473
DNM3 dynamin 3 2.08034
PRKCE protein kinase C, epsilon 2.07948
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 2.07749
RAD51AP1 RAD51 associated protein 1 2.0752
TSFM Ts translation elongation factor, mitochondrial 2.07485
LGI1 leucine-rich, glioma inactivated 1 2.07437
KALRN kalirin, RhoGEF kinase 2.07382
THY1 Thy-1 cell surface antigen 2.07368
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 2.07294
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 2.07273
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.07236
OPCML opioid binding protein/cell adhesion molecule-like 2.07091
IFNA7 interferon, alpha 7 2.07067
CTSF cathepsin F 2.06738
RECK reversion-inducing-cysteine-rich protein with kazal motifs 2.0657
ATG14 autophagy related 14 2.06549
PPP2R2B protein phosphatase 2, regulatory subunit B, beta 2.06442
TRPC3 transient receptor potential cation channel, subfamily C, member 3 2.06346
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 2.06158
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 2.06043
DSCC1 DNA replication and sister chromatid cohesion 1 2.06039
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 2.05953
CBX7 chromobox homolog 7 2.05926
ATL2 atlastin GTPase 2 2.05852
SMIM8 small integral membrane protein 8 2.05758
THRB thyroid hormone receptor, beta 2.0566
SLITRK2 SLIT and NTRK-like family, member 2 2.05572
LOC124907012 endogenous retrovirus group K member 7 Env polyprotein-like 2.05441
IL13RA1 interleukin 13 receptor, alpha 1 2.05374
ATXN10 ataxin 10 2.05352
APCS amyloid P component, serum 2.05335
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) 2.05253
OR10H3 olfactory receptor, family 10, subfamily H, member 3 2.05217
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 2.04703
ZNF257 zinc finger protein 257 2.0459
SLCO3A1 solute carrier organic anion transporter family, member 3A1 2.04552
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.04305
GPR22 G protein-coupled receptor 22 2.04227
ISL1 ISL LIM homeobox 1 2.04042
SLCO1C1 solute carrier organic anion transporter family, member 1C1 2.04002
NOTCH4 notch 4 2.03925
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 2.03851
AJAP1 adherens junctions associated protein 1 2.03743
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.03703
ACSM3 acyl-CoA synthetase medium-chain family member 3 2.03701
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 2.03676
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 2.03615
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 2.03511
ACSL6 acyl-CoA synthetase long-chain family member 6 2.03346
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa 2.03331
CD80 CD80 molecule 2.0314
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 2.03119
RALYL RALY RNA binding protein-like 2.03017
HLA-DMB major histocompatibility complex, class II, DM beta 2.02933
AIRIM AFG2 interacting ribosome maturation factor 2.02875
PSG6 pregnancy specific beta-1-glycoprotein 6 2.02585
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 2.02554
SIRT5 sirtuin 5 2.0221
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 2.02102
SCRN3 secernin 3 2.01887
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 2.01816
KNG1 kininogen 1 2.01608
CASQ2 calsequestrin 2 (cardiac muscle) 2.01573
ARPP21 cAMP-regulated phosphoprotein, 21kDa 2.01469
LMCD1 LIM and cysteine-rich domains 1 2.01372
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta 2.01284
NMBR neuromedin B receptor 2.01282
KIF26B kinesin family member 26B 2.01163
TLR7 toll-like receptor 7 2.01116
MAP3K12 mitogen-activated protein kinase kinase kinase 12 2.01108
EPB41L5 erythrocyte membrane protein band 4.1 like 5 2.01045
PRND prion protein 2 (dublet) 2.00946
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit 2.00829
PSG3 pregnancy specific beta-1-glycoprotein 3 2.0064
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 2.00585
ARL4C ADP-ribosylation factor-like 4C 2.00556
GPRASP1 G protein-coupled receptor associated sorting protein 1 2.00476
ZNF260 zinc finger protein 260 2.00463
ASCL3 achaete-scute family bHLH transcription factor 3 2.00417
PARM1 prostate androgen-regulated mucin-like protein 1 2.00415
APAF1 apoptotic peptidase activating factor 1 2.0037
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 2.00368
SULF1 sulfatase 1 2.00366
CCDC121 coiled-coil domain containing 121 2.00352
KDM7A lysine (K)-specific demethylase 7A 2.00248
IFNA10 interferon, alpha 10 2.00219
TPK1 thiamin pyrophosphokinase 1 2.00152
RWDD3 RWD domain containing 3 2.00127
GRM3 glutamate receptor, metabotropic 3 2.0003
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.00013

decreased expression

Symbol Name Standardized Value
CD320 CD320 molecule -7.08211
EXOSC4 exosome component 4 -5.09967
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -4.9712
YME1L1 YME1-like 1 ATPase -4.87919
AKT1 v-akt murine thymoma viral oncogene homolog 1 -4.85395
TLCD3A TLC domain containing 3A -4.14593
COG7 component of oligomeric golgi complex 7 -4.05997
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -4.0114
MT2A metallothionein 2A -3.99988
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -3.92607
FABP5 fatty acid binding protein 5 (psoriasis-associated) -3.89929
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -3.78245
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -3.76985
KRT14 keratin 14, type I -3.72877
AMDHD2 amidohydrolase domain containing 2 -3.54659
NT5DC2 5'-nucleotidase domain containing 2 -3.48612
TM9SF3 transmembrane 9 superfamily member 3 -3.44544
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -3.12814
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -3.07929
PLK1 polo-like kinase 1 -3.04897
FPGS folylpolyglutamate synthase -2.98444
MPV17L-BMERB1 MPV17L-BMERB1 readthrough -2.88635
PTDSS2 phosphatidylserine synthase 2 -2.86074
GMPPA GDP-mannose pyrophosphorylase A -2.8441
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -2.8373
ARID4B AT rich interactive domain 4B (RBP1-like) -2.80868
TEX10 testis expressed 10 -2.7481
VKORC1 vitamin K epoxide reductase complex, subunit 1 -2.68572
MT1X metallothionein 1X -2.67521
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -2.65089
BASP1 brain abundant, membrane attached signal protein 1 -2.63485
NPY neuropeptide Y -2.61821
GNAS GNAS complex locus -2.59907
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 -2.57679
LOC112694756 uncharaterized LOC112694756 -2.50285
P3H3 prolyl 3-hydroxylase 3 -2.48823
ETFB electron-transfer-flavoprotein, beta polypeptide -2.47478
DCTN5 dynactin 5 (p25) -2.47144
BST2 bone marrow stromal cell antigen 2 -2.45236
OAT ornithine aminotransferase -2.45206
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.42117
CD164 CD164 molecule, sialomucin -2.41685
GIPC1 GIPC PDZ domain containing family, member 1 -2.39049
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -2.38537
CDC20 cell division cycle 20 -2.38506
MTPAP mitochondrial poly(A) polymerase -2.35517
TARS1 threonyl-tRNA synthetase 1 -2.33542
BATF basic leucine zipper transcription factor, ATF-like -2.33268
LINC02762 long intergenic non-protein coding RNA 2762 -2.32959
PYGL phosphorylase, glycogen, liver -2.30211
DEGS1 delta(4)-desaturase, sphingolipid 1 -2.30128
CMTM6 CKLF-like MARVEL transmembrane domain containing 6 -2.2939
UBE3C ubiquitin protein ligase E3C -2.28948
CREG1 cellular repressor of E1A-stimulated genes 1 -2.28579
CCT7 chaperonin containing TCP1, subunit 7 (eta) -2.28456
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -2.28428
NAP1L4 nucleosome assembly protein 1-like 4 -2.2789
PDCD6IP programmed cell death 6 interacting protein -2.27362
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.26327
PNKP polynucleotide kinase 3'-phosphatase -2.24906
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.24813
CAPZB capping protein (actin filament) muscle Z-line, beta -2.22585
TDP1 tyrosyl-DNA phosphodiesterase 1 -2.22133
DCLRE1C DNA cross-link repair 1C -2.22021
IPO4 importin 4 -2.21475
TKT transketolase -2.21046
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -2.20876
NPR2 natriuretic peptide receptor 2 -2.20524
CD81 CD81 molecule -2.20262
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 -2.19402
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -2.1788
KANK2 KN motif and ankyrin repeat domains 2 -2.16536
TBC1D16 TBC1 domain family, member 16 -2.15582
STX10 syntaxin 10 -2.1468
EIF3B eukaryotic translation initiation factor 3, subunit B -2.13756
DUSP4 dual specificity phosphatase 4 -2.13547
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa -2.12626
WASF3 WAS protein family, member 3 -2.1251
UBE2S ubiquitin-conjugating enzyme E2S -2.11905
GOLPH3 golgi phosphoprotein 3 (coat-protein) -2.11064
GDI2 GDP dissociation inhibitor 2 -2.10744
MVP major vault protein -2.09511
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) -2.08126
TOMM34 translocase of outer mitochondrial membrane 34 -2.07678
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -2.07224
PTOV1 prostate tumor overexpressed 1 -2.06592
XPO6 exportin 6 -2.06566
TRIB3 tribbles pseudokinase 3 -2.06427
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -2.04909
ARHGAP12 Rho GTPase activating protein 12 -2.04516
CLIP4 CAP-GLY domain containing linker protein family, member 4 -2.04426
RPA3 replication protein A3, 14kDa -2.0375
TMEM115 transmembrane protein 115 -2.03337
NUDC nudC nuclear distribution protein -2.02273
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -2.02114
ARHGAP17 Rho GTPase activating protein 17 -2.01659
NVL nuclear VCP-like -2.01495