CRCGN017_MCF10A.WT.HP_24H:O06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description UnTrt perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

49 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:O06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCP110 centriolar coiled coil protein 110kDa 10.0
ARID5B AT rich interactive domain 5B (MRF1-like) 5.2916
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 4.9007
GADD45A growth arrest and DNA-damage-inducible, alpha 4.3524
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 4.3413
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.9425
RPP38 ribonuclease P/MRP 38kDa subunit 3.729
DENND2D DENN/MADD domain containing 2D 3.4434
BAMBI BMP and activin membrane-bound inhibitor 3.2043
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 2.9459
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) 2.8753
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.7163
METRN meteorin, glial cell differentiation regulator 2.4616
RUVBL1 RuvB-like AAA ATPase 1 2.4159
PLSCR3 phospholipid scramblase 3 2.35505
TRAPPC6A trafficking protein particle complex 6A 2.3223
KCTD20 potassium channel tetramerization domain containing 20 2.3184
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 2.2498
TEX10 testis expressed 10 2.1975
GAMT guanidinoacetate N-methyltransferase 2.1621
FOXJ1 forkhead box J1 2.1323
HBB hemoglobin, beta 2.09453
NEK4 NIMA-related kinase 4 2.0747
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 2.0636
CNN2 calponin 2 2.0272
BTBD1 BTB (POZ) domain containing 1 2.0245

decreased expression

Symbol Name Standardized Value
NSDHL NAD(P) dependent steroid dehydrogenase-like -7.9152
KRT14 keratin 14, type I -7.3668
PRCP prolylcarboxypeptidase (angiotensinase C) -4.3859
FAIM Fas apoptotic inhibitory molecule -3.3945
KLHL21 kelch-like family member 21 -3.1725
GDI1 GDP dissociation inhibitor 1 -2.5997
SSR4 signal sequence receptor, delta -2.5793
F8A2 coagulation factor VIII-associated 2 -2.5663
CETN2 centrin, EF-hand protein, 2 -2.516
CORO1A coronin, actin binding protein, 1A -2.4903
SLC35G2 solute carrier family 35, member G2 -2.3052
FABP3 fatty acid binding protein 3, muscle and heart -2.2835
ACKR1 atypical chemokine receptor 1 (Duffy blood group) -2.1673
BASP1 brain abundant, membrane attached signal protein 1 -2.1483
MECP2 methyl CpG binding protein 2 -2.13307
FAM50A family with sequence similarity 50, member A -2.1181
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma -2.106
KCTD5 potassium channel tetramerization domain containing 5 -2.0946
BCAP31 B-cell receptor-associated protein 31 -2.0782
DKC1 dyskeratosis congenita 1, dyskerin -2.0729
GET1 guided entry of tail-anchored proteins factor 1 -2.0698
VAMP7 vesicle-associated membrane protein 7 -2.0582
ZNF185 zinc finger protein 185 (LIM domain) -2.046