CRCGN017_MCF10A.WT.HP_24H:O17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dichlorvos 33.79 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

473 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:O17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
EAPP E2F-associated phosphoprotein 5.35705
LYN LYN proto-oncogene, Src family tyrosine kinase 4.74698
NOSIP nitric oxide synthase interacting protein 4.5974
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 3.91245
ZW10 zw10 kinetochore protein 3.7121
SLC35B1 solute carrier family 35, member B1 3.68295
TSPYL5 TSPY-like 5 3.4465
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3.29205
BACE2 beta-site APP-cleaving enzyme 2 3.2353
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 3.2202
USP6NL USP6 N-terminal like 3.18425
TOGARAM1 TOG array regulator of axonemal microtubules 1 3.1368
ZNF586 zinc finger protein 586 3.07485
ELF2 E74-like factor 2 (ets domain transcription factor) 3.06247
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 3.04135
FBXO3 F-box protein 3 3.0362
TLR4 toll-like receptor 4 3.0319
OBP2B odorant binding protein 2B 2.9341
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.8691
SRP54 signal recognition particle 54kDa 2.86205
RBM7 RNA binding motif protein 7 2.8544
GATA3 GATA binding protein 3 2.8436
CCNA1 cyclin A1 2.8418
EFHD1 EF-hand domain family, member D1 2.83865
ABHD18 abhydrolase domain containing 18 2.837
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.82053
GHR growth hormone receptor 2.79495
DPM1 dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit 2.7713
RNF139 ring finger protein 139 2.75585
ZNF669 zinc finger protein 669 2.7554
CDK20 cyclin-dependent kinase 20 2.7359
WIF1 WNT inhibitory factor 1 2.7241
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.71047
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like 2.7054
LEMD3 LEM domain containing 3 2.7029
ACTR6 ARP6 actin-related protein 6 homolog (yeast) 2.69615
TSC1 tuberous sclerosis 1 2.693
COL11A1 collagen, type XI, alpha 1 2.67992
MPC2 mitochondrial pyruvate carrier 2 2.6756
KDM5D lysine (K)-specific demethylase 5D 2.6727
TM2D1 TM2 domain containing 1 2.65602
ZNF8 zinc finger protein 8 2.6373
CELF2 CUGBP, Elav-like family member 2 2.63728
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 2.62748
CCL2 chemokine (C-C motif) ligand 2 2.62695
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 2.623
FBXL5 F-box and leucine-rich repeat protein 5 2.6178
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 2.61175
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 2.6091
TMEM50A transmembrane protein 50A 2.6038
RHOBTB1 Rho-related BTB domain containing 1 2.59935
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 2.59595
GNA14 guanine nucleotide binding protein (G protein), alpha 14 2.5941
NKAPD1 NKAP domain containing 1 2.59395
EPHX3 epoxide hydrolase 3 2.5885
OBP2A odorant binding protein 2A 2.5837
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.57705
GTPBP8 GTP-binding protein 8 (putative) 2.5623
PDGFRL platelet-derived growth factor receptor-like 2.561
TBC1D15 TBC1 domain family, member 15 2.5541
KRABD4 KRAB domain containing 4 2.55245
FAM124B family with sequence similarity 124B 2.538
KLHL29 kelch-like family member 29 2.5275
TSPYL4 TSPY-like 4 2.4942
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 2.48915
MED23 mediator complex subunit 23 2.48525
DIO2 deiodinase, iodothyronine, type II 2.47909
FUBP3 far upstream element (FUSE) binding protein 3 2.4739
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') 2.46585
ANAPC10 anaphase promoting complex subunit 10 2.45355
MYLIP myosin regulatory light chain interacting protein 2.44485
N4BP2L1 NEDD4 binding protein 2-like 1 2.4382
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 2.43385
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 2.42925
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 2.4272
NT5C2 5'-nucleotidase, cytosolic II 2.4208
ZFAND1 zinc finger, AN1-type domain 1 2.4163
CCL23 chemokine (C-C motif) ligand 23 2.41535
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 2.4099
TBPL1 TBP-like 1 2.40965
CRBN cereblon 2.4076
USP9Y ubiquitin specific peptidase 9, Y-linked 2.4062
DIXDC1 DIX domain containing 1 2.3894
TAF11 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa 2.38515
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 2.3806
ISOC1 isochorismatase domain containing 1 2.37515
KAT7 K(lysine) acetyltransferase 7 2.37475
C5 complement component 5 2.3732
NID2 nidogen 2 (osteonidogen) 2.3671
LGMN legumain 2.3667
LY86 lymphocyte antigen 86 2.3613
CCDC28A coiled-coil domain containing 28A 2.36035
SPAG16 sperm associated antigen 16 2.3581
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 2.35625
STAU2 staufen double-stranded RNA binding protein 2 2.35475
CCDC30 coiled-coil domain containing 30 2.35435
CCNC cyclin C 2.3484
TMBIM4 transmembrane BAX inhibitor motif containing 4 2.34795
GPN3 GPN-loop GTPase 3 2.3479
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 2.345
CEP15 centrosomal protein 15 2.3438
NME5 NME/NM23 family member 5 2.33565
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 2.3318
GPR52 G protein-coupled receptor 52 2.3292
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 2.3164
STXBP3 syntaxin binding protein 3 2.3161
TUBD1 tubulin, delta 1 2.30813
VLDLR very low density lipoprotein receptor 2.2993
NAP1L3 nucleosome assembly protein 1-like 3 2.2991
SUMO1 small ubiquitin-like modifier 1 2.29703
SGMS1 sphingomyelin synthase 1 2.29465
NNAT neuronatin 2.28655
USPL1 ubiquitin specific peptidase like 1 2.2828
CASD1 CAS1 domain containing 1 2.2785
GOLGA7 golgin A7 2.27305
TESMIN testis expressed metallothionein like protein 2.26585
OGFRL1 opioid growth factor receptor-like 1 2.26525
TCEAL1 transcription elongation factor A (SII)-like 1 2.2588
SNRPB2 small nuclear ribonucleoprotein polypeptide B 2.2552
DEPTOR DEP domain containing MTOR-interacting protein 2.253
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 2.2482
TPO thyroid peroxidase 2.2433
RAB27A RAB27A, member RAS oncogene family 2.23591
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.23395
ENC1 ectodermal-neural cortex 1 (with BTB domain) 2.23288
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 2.2307
RYR3 ryanodine receptor 3 2.22995
RWDD3 RWD domain containing 3 2.2288
ARHGAP15 Rho GTPase activating protein 15 2.2268
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 2.2265
PRKCQ protein kinase C, theta 2.226
ATP8B4 ATPase, class I, type 8B, member 4 2.224
STAT5A signal transducer and activator of transcription 5A 2.22105
MED13 mediator complex subunit 13 2.21878
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.21655
SNAP91 synaptosomal-associated protein, 91kDa 2.2163
EIF4E eukaryotic translation initiation factor 4E 2.21475
SMG8 SMG8 nonsense mediated mRNA decay factor 2.2136
ZNF587B zinc finger protein 587B 2.21135
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.207
MS4A5 membrane-spanning 4-domains, subfamily A, member 5 2.20185
PLAAT4 phospholipase A and acyltransferase 4 2.2
RBM48 RNA binding motif protein 48 2.19408
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 2.19155
APOC1 apolipoprotein C-I 2.18972
OR7A5 olfactory receptor, family 7, subfamily A, member 5 2.18765
PCTP phosphatidylcholine transfer protein 2.1871
GUCY1B1 guanylate cyclase 1 soluble subunit beta 1 2.17583
TMEM165 transmembrane protein 165 2.17315
ZNF350 zinc finger protein 350 2.1689
CNTNAP1 contactin associated protein 1 2.16665
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 2.1657
CERT1 ceramide transporter 1 2.1638
ZNF143 zinc finger protein 143 2.1615
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 2.16055
TENM4 teneurin transmembrane protein 4 2.1538
PTGDR prostaglandin D2 receptor (DP) 2.1514
GRK3 G protein-coupled receptor kinase 3 2.14663
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) 2.14185
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.14135
RUNDC3B RUN domain containing 3B 2.1395
CST4 cystatin S 2.13775
PTBP2 polypyrimidine tract binding protein 2 2.13595
PACRG PARK2 co-regulated 2.13363
CCDC59 coiled-coil domain containing 59 2.1288
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 2.12415
COMP cartilage oligomeric matrix protein 2.12395
CAPN6 calpain 6 2.12325
EFR3A EFR3 homolog A (S. cerevisiae) 2.12232
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa 2.11665
KIN Kin17 DNA and RNA binding protein 2.11115
CDC73 cell division cycle 73 2.1106
GSAP gamma-secretase activating protein 2.11053
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 2.10975
ZNF222 zinc finger protein 222 2.1078
MIS18BP1 MIS18 binding protein 1 2.1077
PTS 6-pyruvoyltetrahydropterin synthase 2.1037
BCAS2 breast carcinoma amplified sequence 2 2.1002
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 2.09535
JAK2 Janus kinase 2 2.0944
ENTREP1 endosomal transmembrane epsin interactor 1 2.0937
IL7 interleukin 7 2.09175
LIMS1 LIM and senescent cell antigen-like domains 1 2.07877
CD69 CD69 molecule 2.07815
TRIM52 tripartite motif containing 52 2.07725
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 2.07505
PSG7 pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) 2.07125
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.07105
MAGT1 magnesium transporter 1 2.0664
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 2.06635
CCDC25 coiled-coil domain containing 25 2.06605
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 2.06605
ZBTB44 zinc finger and BTB domain containing 44 2.06395
TG thyroglobulin 2.06165
PDLIM3 PDZ and LIM domain 3 2.06005
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 2.05675
SLC38A6 solute carrier family 38, member 6 2.05585
ZNHIT6 zinc finger, HIT-type containing 6 2.0543
ZFY zinc finger protein, Y-linked 2.0534
PWP1 PWP1 homolog (S. cerevisiae) 2.05052
ZNF124 zinc finger protein 124 2.05035
RABL3 RAB, member of RAS oncogene family-like 3 2.04885
CYRIB CYFIP related Rac1 interactor B 2.04815
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 2.0457
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 2.04275
PPP1R3D protein phosphatase 1, regulatory subunit 3D 2.04235
SH3GL3 SH3-domain GRB2-like 3 2.0363
SIDT1 SID1 transmembrane family, member 1 2.036
NANOS3 nanos homolog 3 (Drosophila) 2.03595
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 2.03365
CYLD cylindromatosis (turban tumor syndrome) 2.03253
AZIN2 antizyme inhibitor 2 2.02765
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 2.0271
TBC1D12 TBC1 domain family, member 12 2.02525
MMP26 matrix metallopeptidase 26 2.02385
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 2.02335
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 2.02278
MAP9 microtubule-associated protein 9 2.02175
SCN9A sodium channel, voltage gated, type IX alpha subunit 2.0211
MORF4L1 mortality factor 4 like 1 2.0173
ZNF451 zinc finger protein 451 2.01393
UFL1 UFM1-specific ligase 1 2.01318
FEV FEV (ETS oncogene family) 2.0129
GOLGA8F golgin A8 family, member F 2.0118
CPPED1 calcineurin-like phosphoesterase domain containing 1 2.00705
RIT2 Ras-like without CAAX 2 2.00695
PTPRD protein tyrosine phosphatase, receptor type, D 2.00677
HEBP1 heme binding protein 1 2.00595
TRA2A transformer 2 alpha homolog (Drosophila) 2.00065
DPP6 dipeptidyl-peptidase 6 2.0004

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -6.42992
AKT1 v-akt murine thymoma viral oncogene homolog 1 -5.395
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -5.16885
TUBA4A tubulin, alpha 4a -5.0
KRT14 keratin 14, type I -4.9511
ETFB electron-transfer-flavoprotein, beta polypeptide -4.8579
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -4.83465
PCCB propionyl CoA carboxylase, beta polypeptide -4.8208
VAT1 vesicle amine transport 1 -4.5995
GFUS GDP-L-fucose synthase -4.53625
ECH1 enoyl CoA hydratase 1, peroxisomal -4.4811
PLK1 polo-like kinase 1 -4.45625
UBA1 ubiquitin-like modifier activating enzyme 1 -4.41135
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -4.24785
STXBP2 syntaxin binding protein 2 -4.1335
LOC112694756 uncharaterized LOC112694756 -4.10255
MGAT4B mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B -4.0824
CSK c-src tyrosine kinase -4.07795
TKT transketolase -4.02045
COPS7A COP9 signalosome subunit 7A -3.94695
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -3.90715
SGK1 serum/glucocorticoid regulated kinase 1 -3.82405
DDIT4 DNA-damage-inducible transcript 4 -3.8114
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.7247
TUFM Tu translation elongation factor, mitochondrial -3.6288
NT5DC2 5'-nucleotidase domain containing 2 -3.6176
DERA deoxyribose-phosphate aldolase (putative) -3.5791
KIF2C kinesin family member 2C -3.50343
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -3.45895
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) -3.44858
TFDP1 transcription factor Dp-1 -3.4296
MVP major vault protein -3.3888
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -3.38
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -3.367
RBM42 RNA binding motif protein 42 -3.3625
SORBS3 sorbin and SH3 domain containing 3 -3.35895
MRPS2 mitochondrial ribosomal protein S2 -3.3051
MTA1 metastasis associated 1 -3.29572
VDAC1 voltage-dependent anion channel 1 -3.28597
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative) -3.2692
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -3.2225
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -3.17565
HSPB1 heat shock 27kDa protein 1 -3.1492
AURKB aurora kinase B -3.14915
BCKDK branched chain ketoacid dehydrogenase kinase -3.1491
AMDHD2 amidohydrolase domain containing 2 -3.13935
ATP5F1D ATP synthase F1 subunit delta -3.13055
UQCRC1 ubiquinol-cytochrome c reductase core protein I -3.1257
MT2A metallothionein 2A -3.09335
CLTB clathrin, light chain B -3.09035
PNPLA6 patatin-like phospholipase domain containing 6 -3.0858
RNF40 ring finger protein 40, E3 ubiquitin protein ligase -3.08175
ACOD1 aconitate decarboxylase 1 -3.0624
TWF2 twinfilin actin binding protein 2 -3.03655
NIPSNAP1 nipsnap homolog 1 (C. elegans) -3.01283
ANXA2 annexin A2 -3.00562
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -2.9987
ACTN4 actinin, alpha 4 -2.9977
ADGRE5 adhesion G protein-coupled receptor E5 -2.9961
POLD4 polymerase (DNA-directed), delta 4, accessory subunit -2.9774
FPGS folylpolyglutamate synthase -2.93315
RANGAP1 Ran GTPase activating protein 1 -2.93033
SMC1A structural maintenance of chromosomes 1A -2.9294
MISP mitotic spindle positioning -2.92825
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 -2.92823
CABIN1 calcineurin binding protein 1 -2.92302
POGK pogo transposable element with KRAB domain -2.91515
NUDC nudC nuclear distribution protein -2.89892
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -2.8931
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -2.8909
MAP2K2 mitogen-activated protein kinase kinase 2 -2.88147
BAG6 BCL2-associated athanogene 6 -2.87435
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.8534
APEH acylaminoacyl-peptide hydrolase -2.85045
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -2.84995
MYBBP1A MYB binding protein (P160) 1a -2.83755
INF2 inverted formin, FH2 and WH2 domain containing -2.83575
PUF60 poly-U binding splicing factor 60KDa -2.8123
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.78883
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -2.78475
COL17A1 collagen, type XVII, alpha 1 -2.7743
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -2.7648
TBC1D10B TBC1 domain family, member 10B -2.76065
FARSA phenylalanyl-tRNA synthetase, alpha subunit -2.7582
ERCC2 excision repair cross-complementation group 2 -2.73105
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha -2.725
NR2F6 nuclear receptor subfamily 2, group F, member 6 -2.71175
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -2.7071
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) -2.6965
ZYX zyxin -2.6965
WASF2 WAS protein family, member 2 -2.689
SART1 squamous cell carcinoma antigen recognized by T cells -2.68745
GPS1 G protein pathway suppressor 1 -2.6795
CARMIL1 capping protein regulator and myosin 1 linker 1 -2.67105
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -2.66705
TUBGCP2 tubulin, gamma complex associated protein 2 -2.65258
TNIP1 TNFAIP3 interacting protein 1 -2.65255
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.65115
AATF apoptosis antagonizing transcription factor -2.6439
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) -2.63035
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa -2.61713
PNKP polynucleotide kinase 3'-phosphatase -2.59475
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -2.58775
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) -2.58332
TPM4 tropomyosin 4 -2.5808
CLIP2 CAP-GLY domain containing linker protein 2 -2.57265
SLC67A1 solute carrier family 67 member 1 -2.5654
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -2.56297
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.55805
WDR18 WD repeat domain 18 -2.55755
MUS81 MUS81 structure-specific endonuclease subunit -2.5555
NCLN nicalin -2.5534
SCAP SREBF chaperone -2.54695
TP53BP2 tumor protein p53 binding protein 2 -2.5366
LAMB3 laminin, beta 3 -2.53495
AXIN1 axin 1 -2.53455
DNM2 dynamin 2 -2.52315
CIC capicua transcriptional repressor -2.5214
FOXM1 forkhead box M1 -2.51855
NGRN neugrin, neurite outgrowth associated -2.5133
BCL2L1 BCL2-like 1 -2.51242
AP2M1 adaptor-related protein complex 2, mu 1 subunit -2.50585
WDR13 WD repeat domain 13 -2.50345
CTDNEP1 CTD nuclear envelope phosphatase 1 -2.4739
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites -2.4693
CD320 CD320 molecule -2.45755
MFN2 mitofusin 2 -2.4444
CDC34 cell division cycle 34 -2.4315
MST1R macrophage stimulating 1 receptor -2.42785
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) -2.42445
PLXNB2 plexin B2 -2.4243
MYDGF myeloid-derived growth factor -2.42362
GDF15 growth differentiation factor 15 -2.4183
CDPF1 cysteine-rich, DPF motif domain containing 1 -2.4182
MRPL12 mitochondrial ribosomal protein L12 -2.41585
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -2.41375
HSPD1 heat shock 60kDa protein 1 (chaperonin) -2.41262
RNF126 ring finger protein 126 -2.41223
MRPL30 mitochondrial ribosomal protein L30 -2.4075
SCARB1 scavenger receptor class B, member 1 -2.4066
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 -2.40175
BSG basigin (Ok blood group) -2.3667
CNN2 calponin 2 -2.36565
AP2S1 adaptor-related protein complex 2, sigma 1 subunit -2.36122
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast) -2.35825
TMEM214 transmembrane protein 214 -2.35815
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) -2.35585
RBM10 RNA binding motif protein 10 -2.34833
SF3B2 splicing factor 3b, subunit 2, 145kDa -2.34275
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -2.34265
PACS2 phosphofurin acidic cluster sorting protein 2 -2.34078
CBX4 chromobox homolog 4 -2.33635
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) -2.32915
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -2.32708
DEF6 differentially expressed in FDCP 6 homolog (mouse) -2.32385
CLUH clustered mitochondria (cluA/CLU1) homolog -2.31785
PRRC2A proline-rich coiled-coil 2A -2.30405
MED15 mediator complex subunit 15 -2.29465
PRKCD protein kinase C, delta -2.2823
JADE2 jade family PHD finger 2 -2.27448
POM121C POM121 transmembrane nucleoporin C -2.27273
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -2.2637
FLNA filamin A, alpha -2.26308
FAM3A family with sequence similarity 3, member A -2.26003
MLF2 myeloid leukemia factor 2 -2.2599
REX1BD required for excision 1-B domain containing -2.2514
GRHPR glyoxylate reductase/hydroxypyruvate reductase -2.25103
RNF187 ring finger protein 187 -2.2503
GYS1 glycogen synthase 1 (muscle) -2.2484
CALR calreticulin -2.24485
SEPTIN10 septin 10 -2.24237
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.2422
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 -2.227
BRMS1L breast cancer metastasis-suppressor 1-like -2.225
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 -2.22075
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor -2.22042
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 -2.2192
ARAF A-Raf proto-oncogene, serine/threonine kinase -2.2112
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 -2.2111
IMP4 IMP4, U3 small nucleolar ribonucleoprotein -2.20705
TBL3 transducin (beta)-like 3 -2.2027
ACY1 aminoacylase 1 -2.20025
ASCC2 activating signal cointegrator 1 complex subunit 2 -2.19805
TLN1 talin 1 -2.1965
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide -2.19625
PPP1R13L protein phosphatase 1, regulatory subunit 13 like -2.1818
AARS1 alanyl-tRNA synthetase 1 -2.1801
NUP93 nucleoporin 93kDa -2.1778
MAP1S microtubule-associated protein 1S -2.17555
PFN1 profilin 1 -2.15735
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) -2.14978
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 -2.14825
RUSF1 RUS family member 1 -2.1454
HMGA1 high mobility group AT-hook 1 -2.13453
FSTL3 follistatin-like 3 (secreted glycoprotein) -2.13295
ILK integrin-linked kinase -2.132
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) -2.13182
GMPPA GDP-mannose pyrophosphorylase A -2.13005
TOP6BL TOP6B like initiator of meiotic double strand breaks -2.12865
VARS1 valyl-tRNA synthetase 1 -2.12538
ADISSP adipose secreted signaling protein -2.12415
GAMT guanidinoacetate N-methyltransferase -2.11595
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -2.11585
PRMT5 protein arginine methyltransferase 5 -2.1148
TSPAN4 tetraspanin 4 -2.1141
HRAS Harvey rat sarcoma viral oncogene homolog -2.11195
INTS3 integrator complex subunit 3 -2.10715
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -2.10715
SF3A1 splicing factor 3a, subunit 1, 120kDa -2.10683
MICALL1 MICAL-like 1 -2.10505
ECSIT ECSIT signalling integrator -2.105
TRIM27 tripartite motif containing 27 -2.09333
ZNF219 zinc finger protein 219 -2.08495
ETHE1 ethylmalonic encephalopathy 1 -2.0849
IRF3 interferon regulatory factor 3 -2.0788
MCL1 myeloid cell leukemia 1 -2.07542
MFAP2 microfibrillar-associated protein 2 -2.07025
DUSP9 dual specificity phosphatase 9 -2.0688
RCC1L RCC1 like -2.0663
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 -2.0661
GCN1 GCN1 activator of EIF2AK4 -2.06523
MOGAT1 monoacylglycerol O-acyltransferase 1 -2.065
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha -2.06215
PPP6R1 protein phosphatase 6, regulatory subunit 1 -2.0601
IGLL1 immunoglobulin lambda-like polypeptide 1 -2.05835
UBXN6 UBX domain protein 6 -2.0532
EIF3CL eukaryotic translation initiation factor 3, subunit C-like -2.0497
HPS6 Hermansky-Pudlak syndrome 6 -2.04515
FBXW4 F-box and WD repeat domain containing 4 -2.044
EDC3 enhancer of mRNA decapping 3 -2.043
DDB2 damage-specific DNA binding protein 2, 48kDa -2.0428
KDM5C lysine (K)-specific demethylase 5C -2.0372
GTPBP6 GTP binding protein 6 (putative) -2.03525
BTBD2 BTB (POZ) domain containing 2 -2.02885
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.0259
VAC14 Vac14 homolog (S. cerevisiae) -2.02145
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -2.02115
THOP1 thimet oligopeptidase 1 -2.01915
EFNB1 ephrin-B1 -2.01755
PTOV1 prostate tumor overexpressed 1 -2.0095
FAM50A family with sequence similarity 50, member A -2.00615
KRI1 KRI1 homolog (S. cerevisiae) -2.0033
MAP7D1 MAP7 domain containing 1 -2.00045