| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | reserpine 101.21 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
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111 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:P04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CCP110 | centriolar coiled coil protein 110kDa | 5.30935 |
| INSIG1 | insulin induced gene 1 | 5.11332 |
| STK10 | serine/threonine kinase 10 | 5.09602 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.87857 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.85042 |
| COMP | cartilage oligomeric matrix protein | 4.2331 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | 3.9861 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.68945 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 3.46725 |
| NOSIP | nitric oxide synthase interacting protein | 3.3103 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 3.2765 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 2.99415 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 2.87965 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 2.78005 |
| TBX2 | T-box 2 | 2.77443 |
| NUP133 | nucleoporin 133kDa | 2.6929 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.684 |
| NADSYN1 | NAD synthetase 1 | 2.65845 |
| DENND10 | DENN domain containing 10 | 2.5561 |
| TEX2 | testis expressed 2 | 2.5334 |
| RAB5B | RAB5B, member RAS oncogene family | 2.5332 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | 2.52732 |
| ADD3 | adducin 3 (gamma) | 2.5103 |
| ELOVL6 | ELOVL fatty acid elongase 6 | 2.4974 |
| SARAF | store-operated calcium entry-associated regulatory factor | 2.4963 |
| GRB10 | growth factor receptor-bound protein 10 | 2.48048 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | 2.47885 |
| TRIM11 | tripartite motif containing 11 | 2.47065 |
| MAP7 | microtubule-associated protein 7 | 2.44572 |
| COL16A1 | collagen, type XVI, alpha 1 | 2.436 |
| ACLY | ATP citrate lyase | 2.42442 |
| IPO13 | importin 13 | 2.42345 |
| NMRK1 | nicotinamide riboside kinase 1 | 2.41585 |
| CRYM | crystallin, mu | 2.3839 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | 2.299 |
| LOC124908558 | X antigen family member 1-like | 2.26565 |
| MVD | mevalonate (diphospho) decarboxylase | 2.26265 |
| P3H1 | prolyl 3-hydroxylase 1 | 2.2605 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 2.2593 |
| EVX1 | even-skipped homeobox 1 | 2.2549 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | 2.249 |
| COPS5 | COP9 signalosome subunit 5 | 2.24765 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.21785 |
| SYT1 | synaptotagmin I | 2.21347 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 2.20968 |
| ZBTB11 | zinc finger and BTB domain containing 11 | 2.19395 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) | 2.1492 |
| GSTK1 | glutathione S-transferase kappa 1 | 2.13825 |
| SQSTM1 | sequestosome 1 | 2.12835 |
| KCTD17 | potassium channel tetramerization domain containing 17 | 2.11755 |
| PKN1 | protein kinase N1 | 2.09593 |
| UBQLN2 | ubiquilin 2 | 2.09125 |
| FCHO1 | FCH domain only 1 | 2.0902 |
| SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 | 2.0862 |
| MKRN1 | makorin ring finger protein 1 | 2.07422 |
| UBXN2B | UBX domain protein 2B | 2.07035 |
| ESYT1 | extended synaptotagmin-like protein 1 | 2.0676 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.0574 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 | 2.05555 |
| SQLE | squalene epoxidase | 2.04592 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -6.3163 |
| PCNA | proliferating cell nuclear antigen | -5.65125 |
| BAG3 | BCL2-associated athanogene 3 | -5.33725 |
| SLC35B1 | solute carrier family 35, member B1 | -5.25 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -5.2441 |
| CCNB1 | cyclin B1 | -5.16335 |
| CLTB | clathrin, light chain B | -4.41411 |
| HMG20B | high mobility group 20B | -4.10715 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.9729 |
| C1QBP | complement component 1, q subcomponent binding protein | -2.92395 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.68095 |
| SLN | sarcolipin | -2.6464 |
| TRIP10 | thyroid hormone receptor interactor 10 | -2.6062 |
| GRB2 | growth factor receptor-bound protein 2 | -2.59475 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit | -2.5733 |
| PFN1 | profilin 1 | -2.54085 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) | -2.49538 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.48705 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.3519 |
| AXIN1 | axin 1 | -2.33195 |
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | -2.32045 |
| DCP1A | decapping mRNA 1A | -2.3118 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -2.29265 |
| EXOSC4 | exosome component 4 | -2.2892 |
| YAP1 | Yes-associated protein 1 | -2.27545 |
| PFDN1 | prefoldin subunit 1 | -2.27155 |
| FERRY3 | FERRY endosomal RAB5 effector complex subunit 3 | -2.25025 |
| BAD | BCL2-associated agonist of cell death | -2.24202 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -2.2359 |
| NGRN | neugrin, neurite outgrowth associated | -2.22755 |
| SPDL1 | spindle apparatus coiled-coil protein 1 | -2.21785 |
| TYRP1 | tyrosinase-related protein 1 | -2.2045 |
| DSG1 | desmoglein 1 | -2.1988 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -2.1567 |
| THAP11 | THAP domain containing 11 | -2.15285 |
| DCK | deoxycytidine kinase | -2.1253 |
| VDAC1 | voltage-dependent anion channel 1 | -2.11465 |
| TMEM100 | transmembrane protein 100 | -2.1041 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -2.08995 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | -2.08795 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | -2.0814 |
| CLEC5A | C-type lectin domain family 5, member A | -2.07655 |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | -2.05732 |
| GCFC2 | GC-rich sequence DNA-binding factor 2 | -2.05582 |
| IFNB1 | interferon, beta 1, fibroblast | -2.0543 |
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | -2.0456 |
| DCLRE1B | DNA cross-link repair 1B | -2.04355 |
| EMC9 | ER membrane protein complex subunit 9 | -2.04175 |
| FHIT | fragile histidine triad | -2.02375 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -2.01972 |
| PRMT5 | protein arginine methyltransferase 5 | -2.0029 |
