CRCGN017_MCF10A.WT.HP_24H:P19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-(2-bromo-2-ethylbutanoyl)urea 99.21 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

730 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:P19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 10.0
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 10.0
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 7.72825
SLC35F5 solute carrier family 35, member F5 4.0624
FBXO11 F-box protein 11 3.955
CD96 CD96 molecule 3.7744
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 3.7682
ART3 ADP-ribosyltransferase 3 3.5041
UGT2B10 UDP glucuronosyltransferase 2 family, polypeptide B10 3.4832
S100G S100 calcium binding protein G 3.4803
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1 3.4525
MELTF melanotransferrin 3.3987
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 3.3185
SOX30 SRY (sex determining region Y)-box 30 3.2687
RBMXL2 RNA binding motif protein, X-linked-like 2 3.2504
FAM204A family with sequence similarity 204, member A 3.2384
LMO7 LIM domain 7 3.1971
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 3.1587
CBX8 chromobox homolog 8 3.1418
HTN1 histatin 1 3.1285
MYLK3 myosin light chain kinase 3 3.1202
TRPC1 transient receptor potential cation channel, subfamily C, member 1 3.10123
ACSL6 acyl-CoA synthetase long-chain family member 6 3.0728
GPR85 G protein-coupled receptor 85 3.0421
PAPOLG poly(A) polymerase gamma 3.02995
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 3.0193
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 3.0005
HTN3 histatin 3 2.9912
IFNA6 interferon, alpha 6 2.9904
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 2.9892
ZNF492 zinc finger protein 492 2.9853
SMR3B submaxillary gland androgen regulated protein 3B 2.98105
RANBP17 RAN binding protein 17 2.9801
ADGRE2 adhesion G protein-coupled receptor E2 2.9634
PEX13 peroxisomal biogenesis factor 13 2.9342
LDHAL6B lactate dehydrogenase A-like 6B 2.9297
MTTP microsomal triglyceride transfer protein 2.9294
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.9091
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 2.90828
SPTA1 spectrin, alpha, erythrocytic 1 2.906
TDRD1 tudor domain containing 1 2.9017
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 2.898
QSER1 glutamine and serine rich 1 2.8932
MTRF1L mitochondrial translational release factor 1-like 2.8929
ZNF460 zinc finger protein 460 2.8907
MBNL3 muscleblind-like splicing regulator 3 2.8901
WNT1 wingless-type MMTV integration site family, member 1 2.8868
TRAPPC6A trafficking protein particle complex 6A 2.8588
TRIM58 tripartite motif containing 58 2.8561
CFAP46 cilia and flagella associated protein 46 2.8485
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 2.8439
ACADSB acyl-CoA dehydrogenase, short/branched chain 2.8372
LPAR4 lysophosphatidic acid receptor 4 2.8369
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 2.8342
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 2.8285
TRPC5 transient receptor potential cation channel, subfamily C, member 5 2.8216
ACOT2 acyl-CoA thioesterase 2 2.818
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 2.8126
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1 2.805
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 2.8029
ACOXL acyl-CoA oxidase-like 2.8002
TBXAS1 thromboxane A synthase 1 (platelet) 2.7988
KLHDC8A kelch domain containing 8A 2.798
GYPE glycophorin E (MNS blood group) 2.79442
CADM1 cell adhesion molecule 1 2.79383
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 2.7906
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.7808
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 2.7753
PPP4R4 protein phosphatase 4, regulatory subunit 4 2.7703
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13 2.7663
CEP97 centrosomal protein 97kDa 2.7649
FN3K fructosamine 3 kinase 2.7626
TRAT1 T cell receptor associated transmembrane adaptor 1 2.7596
TEF thyrotrophic embryonic factor 2.7566
PLPP2 phospholipid phosphatase 2 2.7451
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide 2.7394
MSTN myostatin 2.7384
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa 2.7181
PDE11A phosphodiesterase 11A 2.7143
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 2.7115
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 2.7114
LGALS14 lectin, galactoside-binding, soluble, 14 2.7091
SPATA31C1 SPATA31 subfamily C, member 1 2.7074
OR2J3 olfactory receptor, family 2, subfamily J, member 3 2.705
ITGB8 integrin, beta 8 2.69535
FAM13C family with sequence similarity 13, member C 2.6889
SLC25A31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 2.6851
PHAF1 phagosome assembly factor 1 2.6843
ALLC allantoicase 2.6821
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 2.6785
MMP25 matrix metallopeptidase 25 2.677
NABP1 nucleic acid binding protein 1 2.6767
LY6E lymphocyte antigen 6 complex, locus E 2.6706
KNL1 kinetochore scaffold 1 2.6656
AKR1D1 aldo-keto reductase family 1, member D1 2.6645
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 2.6637
LGSN lengsin, lens protein with glutamine synthetase domain 2.656
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 2.6433
CETP cholesteryl ester transfer protein, plasma 2.6433
ATXN7L1 ataxin 7-like 1 2.643
MYH13 myosin, heavy chain 13, skeletal muscle 2.6423
OR2W1 olfactory receptor, family 2, subfamily W, member 1 2.6422
THAP1 THAP domain containing, apoptosis associated protein 1 2.6391
DENND1C DENN/MADD domain containing 1C 2.6355
DGKE diacylglycerol kinase, epsilon 64kDa 2.6347
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 2.6286
NTHL1 nth endonuclease III-like 1 (E. coli) 2.6283
LCT lactase 2.6192
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 2.6188
RCAN3 RCAN family member 3 2.6185
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase 2.6156
PCTP phosphatidylcholine transfer protein 2.6138
PPP1R3A protein phosphatase 1, regulatory subunit 3A 2.6137
CLCN5 chloride channel, voltage-sensitive 5 2.6103
CD5L CD5 molecule-like 2.6087
SPRYD7 SPRY domain containing 7 2.6079
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 2.6075
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 2.6048
PGR progesterone receptor 2.6043
CT55 cancer/testis antigen 55 2.6029
SPICE1 spindle and centriole associated protein 1 2.6017
ZBTB33 zinc finger and BTB domain containing 33 2.6009
IL2RG interleukin 2 receptor, gamma 2.6005
L2HGDH L-2-hydroxyglutarate dehydrogenase 2.5994
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.5982
OR10C1 olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) 2.5966
RHD Rh blood group, D antigen 2.5937
PCDHGA8 protocadherin gamma subfamily A, 8 2.5923
CD226 CD226 molecule 2.5857
CRYBA1 crystallin, beta A1 2.5852
SMR3A submaxillary gland androgen regulated protein 3A 2.5846
TEX12 testis expressed 12 2.5843
CFAP68 cilia and flagella associated protein 68 2.5842
SMAD3 SMAD family member 3 2.58335
ZSCAN5A zinc finger and SCAN domain containing 5A 2.5829
SPATA17 spermatogenesis associated 17 2.5785
ASB9 ankyrin repeat and SOCS box containing 9 2.5764
GRTP1 growth hormone regulated TBC protein 1 2.5715
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae) 2.5708
CMKLR2 chemerin chemokine-like receptor 2 2.5701
ADGB androglobin 2.5691
GCM2 glial cells missing homolog 2 (Drosophila) 2.5635
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) 2.562
PARD6B par-6 family cell polarity regulator beta 2.56135
PPP4R3B protein phosphatase 4 regulatory subunit 3B 2.5566
ELAVL2 ELAV like neuron-specific RNA binding protein 2 2.554
FOXL2 forkhead box L2 2.5515
RNF32 ring finger protein 32 2.5481
PPIAL4H peptidylprolyl isomerase A like 4H 2.5474
TAAR2 trace amine associated receptor 2 2.5439
LPAR6 lysophosphatidic acid receptor 6 2.5439
TIGD6 tigger transposable element derived 6 2.542
GPR25 G protein-coupled receptor 25 2.5416
PHF14 PHD finger protein 14 2.5413
RFX4 regulatory factor X, 4 (influences HLA class II expression) 2.539
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 2.5364
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 2.5308
GP6 glycoprotein VI (platelet) 2.5287
PLSCR2 phospholipid scramblase 2 2.5284
DRD3 dopamine receptor D3 2.52415
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 2.5241
GLRA3 glycine receptor, alpha 3 2.52403
SPATA6L spermatogenesis associated 6-like 2.5215
IL1RAP interleukin 1 receptor accessory protein 2.51765
FBXO24 F-box protein 24 2.5137
FOXD2 forkhead box D2 2.5113
TCP10L t-complex 10-like 2.511
TMOD2 tropomodulin 2 (neuronal) 2.5101
VPS50 VPS50 subunit of EARP/GARPII complex 2.5085
TRIM49B tripartite motif containing 49B 2.5058
MORC1 MORC family CW-type zinc finger 1 2.5034
CCDC70 coiled-coil domain containing 70 2.5022
PHKG2 phosphorylase kinase, gamma 2 (testis) 2.4992
ZNF157 zinc finger protein 157 2.4975
TEX15 testis expressed 15 2.4941
SCIN scinderin 2.494
INVS inversin 2.49197
MTUS2 microtubule associated tumor suppressor candidate 2 2.4918
USP2 ubiquitin specific peptidase 2 2.4914
GPR6 G protein-coupled receptor 6 2.491
HCRT hypocretin (orexin) neuropeptide precursor 2.4886
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.4885
IMPG1 interphotoreceptor matrix proteoglycan 1 2.487
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 2.4862
ANKRD7 ankyrin repeat domain 7 2.4858
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) 2.484
EPB42 erythrocyte membrane protein band 4.2 2.4806
ZNF780B zinc finger protein 780B 2.4788
HID1 HID1 domain containing 2.47665
YOD1 YOD1 deubiquitinase 2.4673
CPLANE1 ciliogenesis and planar polarity effector complex subunit 1 2.4646
SEMG2 semenogelin II 2.4601
PURG purine-rich element binding protein G 2.458
BRDT bromodomain, testis-specific 2.4577
PCDHB8 protocadherin beta 8 2.4574
FOXI1 forkhead box I1 2.4569
DNASE2B deoxyribonuclease II beta 2.4542
ZXDC ZXD family zinc finger C 2.4513
SCN7A sodium channel, voltage gated, type VII alpha subunit 2.4503
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 2.449
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 2.4461
PLA2R1 phospholipase A2 receptor 1, 180kDa 2.4435
CCDC144A coiled-coil domain containing 144A 2.4372
DSTYK dual serine/threonine and tyrosine protein kinase 2.4365
GNAT3 guanine nucleotide binding protein, alpha transducing 3 2.4351
ATXN3L ataxin 3-like 2.4331
MTMR7 myotubularin related protein 7 2.4305
ZNF214 zinc finger protein 214 2.4303
OR2B2 olfactory receptor, family 2, subfamily B, member 2 2.4293
BTBD7 BTB (POZ) domain containing 7 2.42855
MROH9 maestro heat-like repeat family member 9 2.4283
DIAPH3 diaphanous-related formin 3 2.4237
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.4235
GOLGA6B golgin A6 family, member B 2.4233
KIAA1549L KIAA1549-like 2.4233
NOX3 NADPH oxidase 3 2.4221
RFPL1 ret finger protein-like 1 2.4199
RYR2 ryanodine receptor 2 (cardiac) 2.4177
ZNF813 zinc finger protein 813 2.4176
HOXC11 homeobox C11 2.4168
IFNA5 interferon, alpha 5 2.4167
FOXL1 forkhead box L1 2.4162
CRISP2 cysteine-rich secretory protein 2 2.413
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 2.4127
GJA9 gap junction protein, alpha 9, 59kDa 2.4112
UTF1 undifferentiated embryonic cell transcription factor 1 2.4111
MTRF1 mitochondrial translational release factor 1 2.4085
OR2F2 olfactory receptor, family 2, subfamily F, member 2 2.40835
THOC5 THO complex 5 2.40725
ASCL2 achaete-scute family bHLH transcription factor 2 2.4057
ZIC4 Zic family member 4 2.4054
ZNF674 zinc finger protein 674 2.4035
FLT3LG fms-related tyrosine kinase 3 ligand 2.4025
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 2.3986
FBXO22 F-box protein 22 2.3985
GP5 glycoprotein V (platelet) 2.398
NPBWR2 neuropeptides B/W receptor 2 2.3971
DAZL deleted in azoospermia-like 2.3966
FBLN5 fibulin 5 2.3929
TRPC3 transient receptor potential cation channel, subfamily C, member 3 2.3899
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 2.3899
MAGEA8 melanoma antigen family A8 2.3897
VRK3 vaccinia related kinase 3 2.38927
HOXD10 homeobox D10 2.3877
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 2.386
SHH sonic hedgehog 2.3852
TAS2R4 taste receptor, type 2, member 4 2.3845
UBQLN3 ubiquilin 3 2.3844
ZNF234 zinc finger protein 234 2.3839
RAD51B RAD51 paralog B 2.3825
TLL1 tolloid-like 1 2.3812
RPGR retinitis pigmentosa GTPase regulator 2.3809
TSBP1 testis expressed basic protein 1 2.3783
RAVER2 ribonucleoprotein, PTB-binding 2 2.3767
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 2.3747
GLRA1 glycine receptor, alpha 1 2.3733
OPRM1 opioid receptor, mu 1 2.37113
AGBL3 ATP/GTP binding protein-like 3 2.3711
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 2.3686
AGTR2 angiotensin II receptor, type 2 2.36843
TAS2R7 taste receptor, type 2, member 7 2.3674
IFNA2 interferon, alpha 2 2.3673
OR2J2 olfactory receptor, family 2, subfamily J, member 2 2.36435
LGALS13 lectin, galactoside-binding, soluble, 13 2.3627
ZMYM1 zinc finger, MYM-type 1 2.3621
VAX2 ventral anterior homeobox 2 2.3581
SCN11A sodium channel, voltage gated, type XI alpha subunit 2.35805
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 2.3563
CD28 CD28 molecule 2.35463
SPACA1 sperm acrosome associated 1 2.3543
ZFX zinc finger protein, X-linked 2.35215
MAP3K8 mitogen-activated protein kinase kinase kinase 8 2.352
GYPC glycophorin C (Gerbich blood group) 2.3514
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 2.35065
ROPN1B rhophilin associated tail protein 1B 2.3505
HRH4 histamine receptor H4 2.34965
TRIM56 tripartite motif containing 56 2.3496
MBTD1 mbt domain containing 1 2.3487
H4C7 H4 clustered histone 7 2.3476
CCDC30 coiled-coil domain containing 30 2.3473
HES2 hes family bHLH transcription factor 2 2.3468
PBOV1 prostate and breast cancer overexpressed 1 2.3458
ZNF334 zinc finger protein 334 2.3438
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.3421
TAS2R8 taste receptor, type 2, member 8 2.3409
LAMC3 laminin, gamma 3 2.3402
BLZF1 basic leucine zipper nuclear factor 1 2.34
ZBTB7C zinc finger and BTB domain containing 7C 2.3394
GCM1 glial cells missing homolog 1 (Drosophila) 2.3357
CFAP43 cilia and flagella associated protein 43 2.329
USH2A Usher syndrome 2A (autosomal recessive, mild) 2.3275
NUAK2 NUAK family, SNF1-like kinase, 2 2.3274
FOXD3 forkhead box D3 2.3267
HCRTR1 hypocretin (orexin) receptor 1 2.3252
GTPBP10 GTP-binding protein 10 (putative) 2.3216
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 2.3215
NPY2R neuropeptide Y receptor Y2 2.32145
PCDHA2 protocadherin alpha 2 2.3204
FLT4 fms-related tyrosine kinase 4 2.3202
LPA lipoprotein, Lp(a) 2.32
SIRT4 sirtuin 4 2.31745
MAGEB4 melanoma antigen family B4 2.3155
ZNF132 zinc finger protein 132 2.3146
SPATA7 spermatogenesis associated 7 2.312
SLC30A1 solute carrier family 30 (zinc transporter), member 1 2.3117
ZNF80 zinc finger protein 80 2.3102
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 2.30827
G6PC1 glucose-6-phosphatase catalytic subunit 1 2.307
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 2.3063
SNTG2 syntrophin, gamma 2 2.3059
AMELY amelogenin, Y-linked 2.3054
LBX1 ladybird homeobox 1 2.3025
ZXDA zinc finger, X-linked, duplicated A 2.30215
OR7A5 olfactory receptor, family 7, subfamily A, member 5 2.3021
PDPN podoplanin 2.302
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 2.302
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 2.3019
PLAAT1 phospholipase A and acyltransferase 1 2.3015
TBC1D22B TBC1 domain family, member 22B 2.3011
EEA1 early endosome antigen 1 2.30085
PAH phenylalanine hydroxylase 2.30065
OR3A2 olfactory receptor, family 3, subfamily A, member 2 2.2999
NPHP1 nephronophthisis 1 (juvenile) 2.2994
SLC25A30 solute carrier family 25, member 30 2.2978
PDE12 phosphodiesterase 12 2.2956
ZNF571 zinc finger protein 571 2.2954
MAGEB3 melanoma antigen family B3 2.2951
OPRPN opiorphin prepropeptide 2.2944
PRH1-TAS2R14 PRH1-TAS2R14 readthrough 2.2942
TRMT9B tRNA methyltransferase 9B (putative) 2.2921
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 2.2899
MINAR1 membrane integral NOTCH2 associated receptor 1 2.2894
MGAT4C MGAT4 family, member C 2.2891
COQ8B coenzyme Q8B 2.2869
ADAM18 ADAM metallopeptidase domain 18 2.2857
NHLH2 nescient helix loop helix 2 2.2857
IFITM1 interferon induced transmembrane protein 1 2.28525
FOXE3 forkhead box E3 2.2851
TAS2R16 taste receptor, type 2, member 16 2.2828
PRR15L proline rich 15-like 2.2815
ITGA9 integrin, alpha 9 2.2809
ELOA2 elongin A2 2.2784
RERGL RERG/RAS-like 2.2763
EPB41 erythrocyte membrane protein band 4.1 2.27615
KLF1 Kruppel-like factor 1 (erythroid) 2.2759
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 2.27505
NEUROD6 neuronal differentiation 6 2.2743
ATG4A autophagy related 4A, cysteine peptidase 2.2735
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 2.2733
PLSCR3 phospholipid scramblase 3 2.2726
ZNF81 zinc finger protein 81 2.2717
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 2.2713
PDLIM3 PDZ and LIM domain 3 2.268
PACC1 proton activated chloride channel 1 2.2643
PSG2 pregnancy specific beta-1-glycoprotein 2 2.2633
PKD2L2 polycystic kidney disease 2-like 2 2.2618
GLP2R glucagon-like peptide 2 receptor 2.26
CFHR3 complement factor H-related 3 2.2587
OLAH oleoyl-ACP hydrolase 2.258
MPL MPL proto-oncogene, thrombopoietin receptor 2.2561
RGS18 regulator of G-protein signaling 18 2.254
EDDM3A epididymal protein 3A 2.25217
RYR3 ryanodine receptor 3 2.2521
TRPM1 transient receptor potential cation channel, subfamily M, member 1 2.25
IL33 interleukin 33 2.2496
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 2.2492
SKA1 spindle and kinetochore associated complex subunit 1 2.249
TNP2 transition protein 2 (during histone to protamine replacement) 2.24795
GPR68 G protein-coupled receptor 68 2.2463
FAT2 FAT atypical cadherin 2 2.2456
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 2.2449
FXN frataxin 2.2448
GREB1L growth regulation by estrogen in breast cancer-like 2.2415
ZNF391 zinc finger protein 391 2.24125
GPR65 G protein-coupled receptor 65 2.2405
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit 2.2404
PCDHGA1 protocadherin gamma subfamily A, 1 2.2401
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 2.24
CCDC57 coiled-coil domain containing 57 2.2377
XPA xeroderma pigmentosum, complementation group A 2.2371
RNF17 ring finger protein 17 2.23665
PLA2G2F phospholipase A2, group IIF 2.2349
ZNF471 zinc finger protein 471 2.2346
NRDE2 NRDE-2, necessary for RNA interference, domain containing 2.2343
NFE2 nuclear factor, erythroid 2 2.2324
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 2.23205
TREM1 triggering receptor expressed on myeloid cells 1 2.2317
PODNL1 podocan-like 1 2.2288
ZNF585B zinc finger protein 585B 2.2287
CCDC82 coiled-coil domain containing 82 2.2278
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing 2.2277
COL19A1 collagen, type XIX, alpha 1 2.2257
SLCO5A1 solute carrier organic anion transporter family, member 5A1 2.2252
NRG2 neuregulin 2 2.2241
LHCGR luteinizing hormone/choriogonadotropin receptor 2.2215
FOXN2 forkhead box N2 2.2214
CD7 CD7 molecule 2.2205
UBASH3A ubiquitin associated and SH3 domain containing A 2.2197
GYPB glycophorin B (MNS blood group) 2.2183
BTG4 B-cell translocation gene 4 2.2171
RFX3 regulatory factor X, 3 (influences HLA class II expression) 2.2167
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 2.2162
MAGEC3 melanoma antigen family C3 2.2161
HOXA2 homeobox A2 2.216
RIPPLY3 ripply transcriptional repressor 3 2.2147
CYLC2 cylicin, basic protein of sperm head cytoskeleton 2 2.2142
PPP1R17 protein phosphatase 1, regulatory subunit 17 2.2135
RAD21L1 RAD21-like 1 (S. pombe) 2.2124
TLR6 toll-like receptor 6 2.2118
AIG1 androgen-induced 1 2.2115
ZNF749 zinc finger protein 749 2.2114
VEZT vezatin, adherens junctions transmembrane protein 2.2108
KLK15 kallikrein-related peptidase 15 2.2105
NSUN7 NOP2/Sun domain family, member 7 2.2101
MLNR motilin receptor 2.2099
PIWIL1 piwi-like RNA-mediated gene silencing 1 2.2091
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 2.20855
OR52A1 olfactory receptor, family 52, subfamily A, member 1 2.2062
ZNF208 zinc finger protein 208 2.2038
NPVF neuropeptide VF precursor 2.2038
HOXB8 homeobox B8 2.2032
NPAP1 nuclear pore associated protein 1 2.2022
DPPA4 developmental pluripotency associated 4 2.2007
XCR1 chemokine (C motif) receptor 1 2.1959
CNTN5 contactin 5 2.1951
IFNA8 interferon, alpha 8 2.195
PRDM13 PR domain containing 13 2.1948
ZNF23 zinc finger protein 23 2.1946
HSF2BP heat shock transcription factor 2 binding protein 2.1935
CENPI centromere protein I 2.1934
SOX14 SRY (sex determining region Y)-box 14 2.1928
LGALS12 lectin, galactoside-binding, soluble, 12 2.191
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 2.19035
ZMYM5 zinc finger, MYM-type 5 2.1884
EFCC1 EF-hand and coiled-coil domain containing 1 2.187
PCDH11X protocadherin 11 X-linked 2.1824
CDY1 chromodomain protein, Y-linked, 1 2.18105
SPO11 SPO11 meiotic protein covalently bound to DSB 2.1801
CABP5 calcium binding protein 5 2.1777
GALR1 galanin receptor 1 2.1747
NRIP2 nuclear receptor interacting protein 2 2.1742
SSTR1 somatostatin receptor 1 2.1742
GK2 glycerol kinase 2 2.1741
LIFR leukemia inhibitory factor receptor alpha 2.174
GUCY2C guanylate cyclase 2C 2.174
ZNF223 zinc finger protein 223 2.1732
JUP junction plakoglobin 2.1728
RXFP3 relaxin/insulin-like family peptide receptor 3 2.1711
FGF8 fibroblast growth factor 8 (androgen-induced) 2.169
ZNF112 zinc finger protein 112 2.1683
DBF4B DBF4 zinc finger B 2.1645
SFT2D2 SFT2 domain containing 2 2.1632
AKAP5 A kinase (PRKA) anchor protein 5 2.1629
BMP15 bone morphogenetic protein 15 2.1624
ADAM2 ADAM metallopeptidase domain 2 2.1623
HOXD12 homeobox D12 2.1606
ANP32D acidic (leucine-rich) nuclear phosphoprotein 32 family, member D 2.1603
JAKMIP2 janus kinase and microtubule interacting protein 2 2.15975
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.1597
LRTM1 leucine-rich repeats and transmembrane domains 1 2.15785
ZBBX zinc finger, B-box domain containing 2.1574
ZXDB zinc finger, X-linked, duplicated B 2.157
CDH20 cadherin 20, type 2 2.1567
ELAC1 elaC ribonuclease Z 1 2.1563
INSL3 insulin-like 3 (Leydig cell) 2.1561
NKX2-1 NK2 homeobox 1 2.1558
MSR1 macrophage scavenger receptor 1 2.15552
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 2.1537
ATP11A ATPase, class VI, type 11A 2.1532
SYNPO2 synaptopodin 2 2.153
CASS4 Cas scaffolding protein family member 4 2.1526
CD3E CD3e molecule, epsilon (CD3-TCR complex) 2.1517
TAS2R10 taste receptor, type 2, member 10 2.1511
IFI27 interferon, alpha-inducible protein 27 2.1497
SPATA1 spermatogenesis associated 1 2.1474
RRH retinal pigment epithelium-derived rhodopsin homolog 2.1473
CBLN1 cerebellin 1 precursor 2.1453
HCK HCK proto-oncogene, Src family tyrosine kinase 2.145
NMBR neuromedin B receptor 2.1438
GFM1 G elongation factor, mitochondrial 1 2.1438
OR2B6 olfactory receptor, family 2, subfamily B, member 6 2.1435
OR3A1 olfactory receptor, family 3, subfamily A, member 1 2.1421
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa 2.142
R3HCC1L R3H domain and coiled-coil containing 1-like 2.1399
ITPKC inositol-trisphosphate 3-kinase C 2.1399
CRTAM cytotoxic and regulatory T cell molecule 2.1397
PECR peroxisomal trans-2-enoyl-CoA reductase 2.1363
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 2.1352
TNIP3 TNFAIP3 interacting protein 3 2.135
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 2.1346
CYSLTR1 cysteinyl leukotriene receptor 1 2.1338
CDADC1 cytidine and dCMP deaminase domain containing 1 2.1337
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.1324
VENTX VENT homeobox 2.1322
HYAL4 hyaluronoglucosaminidase 4 2.1321
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 2.1311
USP27X ubiquitin specific peptidase 27, X-linked 2.1306
LCOR ligand dependent nuclear receptor corepressor 2.1289
ZNF407 zinc finger protein 407 2.1285
APOF apolipoprotein F 2.1265
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 2.12643
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 2.12625
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 2.1231
LRIT1 leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 2.1226
THAP3 THAP domain containing, apoptosis associated protein 3 2.1223
GSC2 goosecoid homeobox 2 2.1209
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 2.1193
TMEM156 transmembrane protein 156 2.1158
WBP4 WW domain binding protein 4 2.11237
ADCY10 adenylate cyclase 10 (soluble) 2.11085
CCDC198 coiled-coil domain containing 198 2.1102
DPYD dihydropyrimidine dehydrogenase 2.1097
CCDC181 coiled-coil domain containing 181 2.1085
ZNF548 zinc finger protein 548 2.1081
TTBK2 tau tubulin kinase 2 2.1072
CRISP1 cysteine-rich secretory protein 1 2.1063
MICB MHC class I polypeptide-related sequence B 2.1059
DCC DCC netrin 1 receptor 2.105
MYT1L myelin transcription factor 1-like 2.10455
PDE4D phosphodiesterase 4D, cAMP-specific 2.1044
TSSK2 testis-specific serine kinase 2 2.1039
KIAA0408 KIAA0408 2.1038
FAM135A family with sequence similarity 135, member A 2.1032
IFNA16 interferon, alpha 16 2.10225
TRIM10 tripartite motif containing 10 2.10203
CDH19 cadherin 19, type 2 2.10165
MILR1 mast cell immunoglobulin-like receptor 1 2.0994
RPE65 retinal pigment epithelium-specific protein 65kDa 2.0992
IRGC immunity-related GTPase family, cinema 2.0986
CFAP73 cilia and flagella associated protein 73 2.09857
EXOC6B exocyst complex component 6B 2.0979
KIF24 kinesin family member 24 2.0955
TAAR5 trace amine associated receptor 5 2.0952
AFF4 AF4/FMR2 family, member 4 2.0946
FPGT-TNNI3K FPGT-TNNI3K readthrough 2.0926
DPF3 D4, zinc and double PHD fingers, family 3 2.0922
TLR5 toll-like receptor 5 2.0914
RABIF RAB interacting factor 2.091
PCDHA9 protocadherin alpha 9 2.0891
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 2.0889
SLC16A8 solute carrier family 16 (monocarboxylate transporter), member 8 2.0881
PSORS1C1 psoriasis susceptibility 1 candidate 1 2.0878
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 2.086
KLHL35 kelch-like family member 35 2.0848
HOXA1 homeobox A1 2.0845
IL1RAPL2 interleukin 1 receptor accessory protein-like 2 2.0843
XYLB xylulokinase homolog (H. influenzae) 2.08295
PSG3 pregnancy specific beta-1-glycoprotein 3 2.08193
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 2.0806
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 2.0805
LGMN legumain 2.0801
GRK4 G protein-coupled receptor kinase 4 2.0785
ZNF440 zinc finger protein 440 2.0777
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 2.07765
CBX2 chromobox homolog 2 2.0761
PTTG2 pituitary tumor-transforming 2 2.0761
PAPOLB poly(A) polymerase beta (testis specific) 2.0737
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28 2.0727
FSHR follicle stimulating hormone receptor 2.0719
STON1-GTF2A1L STON1-GTF2A1L readthrough 2.0713
IFT74 intraflagellar transport 74 2.0712
CD101 CD101 molecule 2.0706
FGF12 fibroblast growth factor 12 2.06955
MEP1A meprin A, alpha (PABA peptide hydrolase) 2.0689
NEUROG2 neurogenin 2 2.066
HYDIN HYDIN, axonemal central pair apparatus protein 2.0647
NR6A1 nuclear receptor subfamily 6, group A, member 1 2.06448
TUBAL3 tubulin, alpha-like 3 2.0643
ZNF550 zinc finger protein 550 2.0637
CRYBA4 crystallin, beta A4 2.0631
CNTNAP3B contactin associated protein-like 3B 2.0625
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 2.06085
DRC8 dynein regulatory complex subunit 8 2.0608
DGKH diacylglycerol kinase, eta 2.0604
WDHD1 WD repeat and HMG-box DNA binding protein 1 2.06033
MREG melanoregulin 2.0588
CD33 CD33 molecule 2.0588
H2BC11 H2B clustered histone 11 2.0587
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 2.0586
GJD3 gap junction protein, delta 3, 31.9kDa 2.0583
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 2.0581
AMELX amelogenin, X-linked 2.0575
ADAM7 ADAM metallopeptidase domain 7 2.0575
SCARF1 scavenger receptor class F, member 1 2.0561
ZCCHC10 zinc finger, CCHC domain containing 10 2.0549
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 2.0528
CA8 carbonic anhydrase VIII 2.0527
ZNF493 zinc finger protein 493 2.0524
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 2.05215
DRD1 dopamine receptor D1 2.0517
FHL5 four and a half LIM domains 5 2.0512
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13 2.0508
MCPH1 microcephalin 1 2.0502
OR1D4 olfactory receptor, family 1, subfamily D, member 4 (gene/pseudogene) 2.0495
HMHB1 histocompatibility (minor) HB-1 2.0492
QPCTL glutaminyl-peptide cyclotransferase-like 2.049
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 2.0487
CEP41 centrosomal protein 41kDa 2.046
SMIM8 small integral membrane protein 8 2.0459
KRT37 keratin 37, type I 2.0456
BTC betacellulin 2.0434
OLFM1 olfactomedin 1 2.04327
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1 2.0432
CA3 carbonic anhydrase III 2.0427
TBR1 T-box, brain, 1 2.042
TRIM66 tripartite motif containing 66 2.0413
RIBC2 RIB43A domain with coiled-coils 2 2.041
CD247 CD247 molecule 2.0401
WT1 Wilms tumor 1 2.03985
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 2.0397
TTC22 tetratricopeptide repeat domain 22 2.03913
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.03775
PRDM9 PR domain containing 9 2.0367
F13B coagulation factor XIII, B polypeptide 2.036
ZNF225 zinc finger protein 225 2.0358
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 2.0351
THPO thrombopoietin 2.03337
CRABP1 cellular retinoic acid binding protein 1 2.0311
RSC1A1 regulatory solute carrier protein, family 1, member 1 2.0301
TXK TXK tyrosine kinase 2.0275
MTNR1A melatonin receptor 1A 2.0274
CCDC121 coiled-coil domain containing 121 2.0258
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 2.0253
PCDHB6 protocadherin beta 6 2.0247
SCN10A sodium channel, voltage gated, type X alpha subunit 2.0228
KERA keratocan 2.022
GSG1 germ cell associated 1 2.0205
GIMAP6 GTPase, IMAP family member 6 2.0204
AQP5 aquaporin 5 2.0202
OCM2 oncomodulin 2 2.0201
KLF8 Kruppel-like factor 8 2.0191
PLCH1 phospholipase C, eta 1 2.01853
LMBR1L limb development membrane protein 1-like 2.0183
GNRHR gonadotropin-releasing hormone receptor 2.01753
LRRC3 leucine rich repeat containing 3 2.0173
CCDC33 coiled-coil domain containing 33 2.014
USP53 ubiquitin specific peptidase 53 2.0138
ADRA1D adrenoceptor alpha 1D 2.01225
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 2.0115
TAS2R9 taste receptor, type 2, member 9 2.0103
CEP135 centrosomal protein 135kDa 2.0094
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 2.0079
MSH4 mutS homolog 4 2.0076
ASCL3 achaete-scute family bHLH transcription factor 3 2.0072
CINP cyclin-dependent kinase 2 interacting protein 2.0065
POU3F4 POU class 3 homeobox 4 2.0056
SLITRK5 SLIT and NTRK-like family, member 5 2.00475
SCAI suppressor of cancer cell invasion 2.0047
KCNK13 potassium channel, two pore domain subfamily K, member 13 2.0036
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 2.0034
CASP7 caspase 7, apoptosis-related cysteine peptidase 2.0029
SLITRK3 SLIT and NTRK-like family, member 3 2.0029
LOC105379278 uncharacterized LOC105379278 2.0027
IFNA1 interferon, alpha 1 2.0001

decreased expression

Symbol Name Standardized Value
ENOPH1 enolase-phosphatase 1 -10.0
BASP1 brain abundant, membrane attached signal protein 1 -7.6194
TLCD3A TLC domain containing 3A -5.2664
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -4.4429
CHERP calcium homeostasis endoplasmic reticulum protein -3.35545
RPS5 ribosomal protein S5 -3.296
CDKN2A cyclin-dependent kinase inhibitor 2A -3.10883
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 -2.9343
COPS4 COP9 signalosome subunit 4 -2.8519
INTS12 integrator complex subunit 12 -2.8346
RAB3A RAB3A, member RAS oncogene family -2.7682
SEC31A SEC31 homolog A (S. cerevisiae) -2.7678
FIP1L1 factor interacting with PAPOLA and CPSF1 -2.7606
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B -2.7219
SEC24B SEC24 family member B -2.7214
SETBP1 SET binding protein 1 -2.7186
ANKMY2 ankyrin repeat and MYND domain containing 2 -2.6829
KRI1 KRI1 homolog (S. cerevisiae) -2.6683
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.664
USP21 ubiquitin specific peptidase 21 -2.6524
TYK2 tyrosine kinase 2 -2.6057
DENND4B DENN/MADD domain containing 4B -2.5506
SLBP stem-loop binding protein -2.5123
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -2.4906
RPL38 ribosomal protein L38 -2.4896
SFMBT1 Scm-like with four mbt domains 1 -2.4573
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) -2.4441
PCNP PEST proteolytic signal containing nuclear protein -2.4427
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 -2.4401
RPL29 ribosomal protein L29 -2.42655
SH3BP4 SH3-domain binding protein 4 -2.3865
MSMO1 methylsterol monooxygenase 1 -2.3573
RIPOR1 RHO family interacting cell polarization regulator 1 -2.3402
TAC4 tachykinin 4 (hemokinin) -2.3402
NELFA negative elongation factor complex member A -2.3341
SUZ12 SUZ12 polycomb repressive complex 2 subunit -2.3277
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) -2.29975
RPL19 ribosomal protein L19 -2.2855
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa -2.2689
RPL4 ribosomal protein L4 -2.2628
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -2.2449
GRPEL1 GrpE-like 1, mitochondrial (E. coli) -2.24295
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -2.2407
G0S2 G0/G1 switch 2 -2.2369
SMAP1 small ArfGAP 1 -2.2367
TBC1D16 TBC1 domain family, member 16 -2.2333
RPS29 ribosomal protein S29 -2.2322
CCNG2 cyclin G2 -2.22323
CTSZ cathepsin Z -2.2179
CBX6 chromobox homolog 6 -2.2111
RPS12 ribosomal protein S12 -2.2098
KRT14 keratin 14, type I -2.209
PAAF1 proteasomal ATPase-associated factor 1 -2.1906
LMTK1 lemur tail kinase 1 -2.1881
PLBD1 phospholipase B domain containing 1 -2.186
LSG1 large 60S subunit nuclear export GTPase 1 -2.1858
AATF apoptosis antagonizing transcription factor -2.1663
RPL34 ribosomal protein L34 -2.1599
DEF8 differentially expressed in FDCP 8 homolog (mouse) -2.1418
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.1308
MAP2K1 mitogen-activated protein kinase kinase 1 -2.1242
NELL1 NEL-like 1 (chicken) -2.1084
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) -2.0992
EMC8 ER membrane protein complex subunit 8 -2.0771
CCP110 centriolar coiled coil protein 110kDa -2.0752
HSPA1A heat shock 70kDa protein 1A -2.0719
RRAGA Ras-related GTP binding A -2.0694
GOLM1 golgi membrane protein 1 -2.0617
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like -2.04515
EIF3L eukaryotic translation initiation factor 3, subunit L -2.0441
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 -2.0314
EXOSC9 exosome component 9 -2.0273
STEAP1 six transmembrane epithelial antigen of the prostate 1 -2.0111
RPL36A ribosomal protein L36a -2.005
RPS7 ribosomal protein S7 -2.00265
UBA6 ubiquitin-like modifier activating enzyme 6 -2.0006