CRCGN017_MCF10A.WT.HP_24H:P20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description n-(2-bromo-2-ethylbutanoyl)urea 33.07 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

593 genes differentially expressed following the CRCGN017_MCF10A.WT.HP_24H:P20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 10.0
SPAG4 sperm associated antigen 4 10.0
IDE insulin-degrading enzyme 8.73577
KIF5C kinesin family member 5C 8.13065
ANO10 anoctamin 10 7.073
NRBF2 nuclear receptor binding factor 2 6.5835
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 6.2017
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 6.0091
CNRIP1 cannabinoid receptor interacting protein 1 4.943
CCDC6 coiled-coil domain containing 6 4.8605
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 4.7955
USP6 ubiquitin specific peptidase 6 4.6097
FLG filaggrin 4.5734
FCHO1 FCH domain only 1 4.5362
KDM5D lysine (K)-specific demethylase 5D 4.48
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 4.2739
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 4.2343
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) 4.1166
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 4.111
BACE1 beta-site APP-cleaving enzyme 1 4.0666
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 4.06
RB1 retinoblastoma 1 3.99075
EXD2 exonuclease 3'-5' domain containing 2 3.9182
TSPAN8 tetraspanin 8 3.8682
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 3.8168
TBC1D12 TBC1 domain family, member 12 3.7957
STMN4 stathmin-like 4 3.7515
LORICRIN loricrin cornified envelope precursor protein 3.7482
KRT2 keratin 2, type II 3.737
ABHD5 abhydrolase domain containing 5 3.655
RABL3 RAB, member of RAS oncogene family-like 3 3.6448
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 3.549
LCE2B late cornified envelope 2B 3.5288
INTS6 integrator complex subunit 6 3.472
HAL histidine ammonia-lyase 3.45595
JRKL JRK-like 3.446
MBOAT2 membrane bound O-acyltransferase domain containing 2 3.4121
STX12 syntaxin 12 3.40895
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7 3.3995
KLHL12 kelch-like family member 12 3.3691
UROS uroporphyrinogen III synthase 3.3688
GSTZ1 glutathione S-transferase zeta 1 3.3427
SOCS5 suppressor of cytokine signaling 5 3.34173
PIGV phosphatidylinositol glycan anchor biosynthesis, class V 3.33965
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 3.3304
ADGRL3 adhesion G protein-coupled receptor L3 3.28365
PPP1R3D protein phosphatase 1, regulatory subunit 3D 3.27735
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 3.2726
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked 3.26257
ZNF197 zinc finger protein 197 3.2595
NLGN4X neuroligin 4, X-linked 3.2367
TSPAN31 tetraspanin 31 3.19785
LMO2 LIM domain only 2 (rhombotin-like 1) 3.1476
CSNK1A1 casein kinase 1, alpha 1 3.12705
PDZD8 PDZ domain containing 8 3.1005
USP9Y ubiquitin specific peptidase 9, Y-linked 3.09345
ATP7B ATPase, Cu++ transporting, beta polypeptide 3.0865
DOCK2 dedicator of cytokinesis 2 3.0643
DSG1 desmoglein 1 3.0553
RBKS ribokinase 3.0515
SLPI secretory leukocyte peptidase inhibitor 3.04435
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 3.0361
THAP10 THAP domain containing 10 3.0326
IFI27 interferon, alpha-inducible protein 27 3.0285
CLIP2 CAP-GLY domain containing linker protein 2 3.0282
ACOT8 acyl-CoA thioesterase 8 3.0278
CADPS2 Ca++-dependent secretion activator 2 3.0272
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 3.0194
ALG11 ALG11, alpha-1,2-mannosyltransferase 3.009
CHODL chondrolectin 3.0064
SLAMF1 signaling lymphocytic activation molecule family member 1 3.0025
SIPA1 signal-induced proliferation-associated 1 3.0006
DEFB1 defensin, beta 1 2.9986
POF1B premature ovarian failure, 1B 2.9902
TGM5 transglutaminase 5 2.9847
AHNAK AHNAK nucleoprotein 2.9691
SYNGR2 synaptogyrin 2 2.9636
TMEM254 transmembrane protein 254 2.9623
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 2.9597
NDST4 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 2.9477
BCL6 B-cell CLL/lymphoma 6 2.94605
ZNF35 zinc finger protein 35 2.9241
PEF1 penta-EF-hand domain containing 1 2.92
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 2.91695
RTN3 reticulon 3 2.9081
ANOS1 anosmin 1 2.8953
EIF3CL eukaryotic translation initiation factor 3, subunit C-like 2.8935
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4 2.89007
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4 2.8803
HOXA1 homeobox A1 2.8703
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant 2.8546
STYXL1 serine/threonine/tyrosine interacting-like 1 2.8533
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 2.8449
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans) 2.84135
PRDX5 peroxiredoxin 5 2.83005
GSTT1 glutathione S-transferase theta 1 2.829
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 2.8283
TRAPPC11 trafficking protein particle complex 11 2.8244
PGGT1B protein geranylgeranyltransferase type I, beta subunit 2.81385
ACSBG1 acyl-CoA synthetase bubblegum family member 1 2.7998
CHP2 calcineurin-like EF-hand protein 2 2.7921
FJX1 four jointed box 1 (Drosophila) 2.7918
ATP9B ATPase, class II, type 9B 2.78965
EFCAB14 EF-hand calcium binding domain 14 2.7885
ACTA2 actin, alpha 2, smooth muscle, aorta 2.7636
RHOBTB1 Rho-related BTB domain containing 1 2.7545
ZNF217 zinc finger protein 217 2.7498
TRIL TLR4 interactor with leucine-rich repeats 2.74705
SYT12 synaptotagmin XII 2.7382
UEVLD UEV and lactate/malate dehyrogenase domains 2.7247
ULK2 unc-51 like autophagy activating kinase 2 2.7202
OCRL oculocerebrorenal syndrome of Lowe 2.7129
TTC12 tetratricopeptide repeat domain 12 2.7112
PTGDR prostaglandin D2 receptor (DP) 2.6957
ZNF518A zinc finger protein 518A 2.6784
MAP3K8 mitogen-activated protein kinase kinase kinase 8 2.6592
SNX19 sorting nexin 19 2.6588
RBM7 RNA binding motif protein 7 2.6561
PAQR6 progestin and adipoQ receptor family member VI 2.6554
RAMP1 receptor (G protein-coupled) activity modifying protein 1 2.6548
IFI6 interferon, alpha-inducible protein 6 2.6543
KPLCE KPRP N-terminal and LCE C-terminal like protein 2.6491
WIPF2 WAS/WASL interacting protein family, member 2 2.64473
AGR2 anterior gradient 2 2.6406
KRT34 keratin 34, type I 2.6406
HSPA1L heat shock 70kDa protein 1-like 2.6382
SLC46A3 solute carrier family 46, member 3 2.6376
PCBP4 poly(rC) binding protein 4 2.6371
BATF3 basic leucine zipper transcription factor, ATF-like 3 2.6363
CX3CR1 chemokine (C-X3-C motif) receptor 1 2.6359
CLASP2 cytoplasmic linker associated protein 2 2.63373
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 2.629
ZNF510 zinc finger protein 510 2.6276
TMEM165 transmembrane protein 165 2.6264
STOML1 stomatin (EPB72)-like 1 2.6211
MAB21L1 mab-21-like 1 (C. elegans) 2.6153
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) 2.6109
R3HDM2 R3H domain containing 2 2.6066
NUAK1 NUAK family, SNF1-like kinase, 1 2.6036
KCNK7 potassium channel, two pore domain subfamily K, member 7 2.6001
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 2.5993
FIBP fibroblast growth factor (acidic) intracellular binding protein 2.597
ABRAXAS2 abraxas 2, BRISC complex subunit 2.59645
ABLIM1 actin binding LIM protein 1 2.5946
TMEM134 transmembrane protein 134 2.5927
KIF1B kinesin family member 1B 2.5921
RAP2C RAP2C, member of RAS oncogene family 2.5887
CCL22 chemokine (C-C motif) ligand 22 2.5867
TXNRD3 thioredoxin reductase 3 2.5852
CCDC186 coiled-coil domain containing 186 2.5838
LOC128966586 pepsin A-4-like 2.5833
PGAM2 phosphoglycerate mutase 2 (muscle) 2.5815
NLGN4Y neuroligin 4, Y-linked 2.5764
UBE2W ubiquitin-conjugating enzyme E2W (putative) 2.5741
RBM12 RNA binding motif protein 12 2.57335
TAGLN2 transgelin 2 2.57265
CBLIF cobalamin binding intrinsic factor 2.562
PSORS1C2 psoriasis susceptibility 1 candidate 2 2.5604
EDC3 enhancer of mRNA decapping 3 2.5596
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 2.55793
KRT33A keratin 33A, type I 2.5523
PARVA parvin, alpha 2.54833
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2.54655
FNBP1 formin binding protein 1 2.54555
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2) 2.5431
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 2.5401
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa 2.537
INHBB inhibin, beta B 2.5351
SLC35A5 solute carrier family 35, member A5 2.534
RELN reelin 2.5265
LTA lymphotoxin alpha 2.5263
TMEM209 transmembrane protein 209 2.5257
UNC13B unc-13 homolog B (C. elegans) 2.525
ZNF329 zinc finger protein 329 2.5247
DUSP2 dual specificity phosphatase 2 2.5208
MLPH melanophilin 2.5197
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 2.5161
LPAR1 lysophosphatidic acid receptor 1 2.51473
FSCN3 fascin actin-bundling protein 3, testicular 2.5144
OSER1 oxidative stress responsive serine-rich 1 2.51315
SPATA2 spermatogenesis associated 2 2.50935
SAMHD1 SAM domain and HD domain 1 2.5068
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 2.5
ACSS3 acyl-CoA synthetase short-chain family member 3 2.4988
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 2.4957
TZMP1 transition zone microprotein 1 2.49535
AGTPBP1 ATP/GTP binding protein 1 2.4915
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 2.4841
CDSN corneodesmosin 2.4799
PGAP4 post-GPI attachment to proteins GalNAc transferase 4 2.4796
ACOX3 acyl-CoA oxidase 3, pristanoyl 2.4742
POLK polymerase (DNA directed) kappa 2.4655
ENDOD1 endonuclease domain containing 1 2.4641
CERS1 ceramide synthase 1 2.464
CCDC22 coiled-coil domain containing 22 2.46255
TMEM267 transmembrane protein 267 2.4515
MSMB microseminoprotein, beta- 2.4508
SGPL1 sphingosine-1-phosphate lyase 1 2.4496
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 2.4417
LDHC lactate dehydrogenase C 2.4321
ALOX15 arachidonate 15-lipoxygenase 2.4269
GPN2 GPN-loop GTPase 2 2.4253
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.4249
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 2.4249
SGSM3 small G protein signaling modulator 3 2.42247
BBS10 Bardet-Biedl syndrome 10 2.4172
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 2.4153
PMP2 peripheral myelin protein 2 2.4069
MRPL48 mitochondrial ribosomal protein L48 2.4065
FHIT fragile histidine triad 2.4001
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa 2.3996
KAT6B K(lysine) acetyltransferase 6B 2.39922
AGO4 argonaute RISC catalytic component 4 2.3967
FOXJ2 forkhead box J2 2.3898
TMOD1 tropomodulin 1 2.38505
LY75-CD302 LY75-CD302 readthrough 2.3796
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 2.377
HAUS3 HAUS augmin-like complex, subunit 3 2.3731
THNSL2 threonine synthase-like 2 (S. cerevisiae) 2.3626
SLC49A3 solute carrier family 49 member 3 2.3606
CNKSR3 CNKSR family member 3 2.3594
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 2.3536
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 2.3516
ZNF134 zinc finger protein 134 2.3512
NCAN neurocan 2.3499
SH3GLB2 SH3-domain GRB2-like endophilin B2 2.3466
ISG15 ISG15 ubiquitin-like modifier 2.3441
KRT85 keratin 85, type II 2.3407
SSH3 slingshot protein phosphatase 3 2.3372
PTPN9 protein tyrosine phosphatase, non-receptor type 9 2.3349
STIL SCL/TAL1 interrupting locus 2.3339
RC3H2 ring finger and CCCH-type domains 2 2.3313
CCL17 chemokine (C-C motif) ligand 17 2.3288
RSPH14 radial spoke head 14 homolog (Chlamydomonas) 2.3279
KRT86 keratin 86, type II 2.3265
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 2.3245
HCFC2 host cell factor C2 2.3221
SAYSD1 SAYSVFN motif domain containing 1 2.3203
RAB5B RAB5B, member RAS oncogene family 2.3201
DOCK1 dedicator of cytokinesis 1 2.3135
FAM168A family with sequence similarity 168, member A 2.3124
ZFY zinc finger protein, Y-linked 2.3097
FTSJ1 FtsJ RNA methyltransferase homolog 1 (E. coli) 2.30825
EIF3I eukaryotic translation initiation factor 3, subunit I 2.308
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 2.3079
PRRC1 proline-rich coiled-coil 1 2.3038
PDIA2 protein disulfide isomerase family A, member 2 2.3023
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.2991
KRT31 keratin 31, type I 2.2985
LY6G6C lymphocyte antigen 6 complex, locus G6C 2.2962
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 2.2954
PCDH9 protocadherin 9 2.29225
TTPAL tocopherol (alpha) transfer protein-like 2.2878
YARS1 tyrosyl-tRNA synthetase 1 2.2876
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 2.2872
TSPAN1 tetraspanin 1 2.2788
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 2.26915
LY86 lymphocyte antigen 86 2.2685
PLXDC2 plexin domain containing 2 2.2679
ANXA11 annexin A11 2.26475
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 2.2607
PDCL phosducin-like 2.2606
PADI2 peptidyl arginine deiminase, type II 2.2596
ZNF548 zinc finger protein 548 2.2589
PLAGL2 pleiomorphic adenoma gene-like 2 2.25225
BICD1 bicaudal D homolog 1 (Drosophila) 2.2522
TMOD3 tropomodulin 3 (ubiquitous) 2.2464
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) 2.2401
CGRRF1 cell growth regulator with ring finger domain 1 2.2347
ADGRB3 adhesion G protein-coupled receptor B3 2.233
TRIM68 tripartite motif containing 68 2.2329
TBXAS1 thromboxane A synthase 1 (platelet) 2.2322
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 2.2315
SPINK1 serine peptidase inhibitor, Kazal type 1 2.2311
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 2.23003
PCYOX1L prenylcysteine oxidase 1 like 2.2265
PRR14L proline rich 14-like 2.2262
PRPH2 peripherin 2 (retinal degeneration, slow) 2.2255
LAMA2 laminin, alpha 2 2.21997
RSBN1 round spermatid basic protein 1 2.2189
SPTBN2 spectrin, beta, non-erythrocytic 2 2.2181
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 2.2177
TOLLIP toll interacting protein 2.2152
OSBPL1A oxysterol binding protein-like 1A 2.2136
JMJD1C jumonji domain containing 1C 2.2126
XPO4 exportin 4 2.212
MED7 mediator complex subunit 7 2.2118
FKTN fukutin 2.2102
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 2.2053
CHKA choline kinase alpha 2.20505
DHRS7B dehydrogenase/reductase (SDR family) member 7B 2.2047
MAPK6 mitogen-activated protein kinase 6 2.198
CAB39L calcium binding protein 39-like 2.197
FAM131B family with sequence similarity 131, member B 2.1956
TFEB transcription factor EB 2.1951
FA2H fatty acid 2-hydroxylase 2.1922
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1 2.1915
FKBP6 FK506 binding protein 6, 36kDa 2.1855
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.1854
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma 2.1812
USP2 ubiquitin specific peptidase 2 2.1767
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 2.1704
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B 2.17
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 2.1668
ADAM15 ADAM metallopeptidase domain 15 2.1651
ARMCX5 armadillo repeat containing, X-linked 5 2.1641
NIBAN1 niban apoptosis regulator 1 2.1628
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 2.1622
ZNF365 zinc finger protein 365 2.1582
TSHZ2 teashirt zinc finger homeobox 2 2.1579
MVB12B multivesicular body subunit 12B 2.14883
GMEB1 glucocorticoid modulatory element binding protein 1 2.146
CREB3L1 cAMP responsive element binding protein 3-like 1 2.1432
NXF3 nuclear RNA export factor 3 2.1426
ELF2 E74-like factor 2 (ets domain transcription factor) 2.1425
PXMP4 peroxisomal membrane protein 4, 24kDa 2.1417
CTSF cathepsin F 2.1391
TESC tescalcin 2.1384
IZUMO4 IZUMO family member 4 2.13665
CCDC169-SOHLH2 CCDC169-SOHLH2 readthrough 2.1355
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1 2.1354
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.1353
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 2.1335
TMEM265 transmembrane protein 265 2.13285
SYTL2 synaptotagmin-like 2 2.1321
AQP5 aquaporin 5 2.1319
MFAP3 microfibrillar-associated protein 3 2.1319
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 2.1269
HOMER1 homer scaffolding protein 1 2.1255
DENND2A DENN/MADD domain containing 2A 2.12475
STXBP3 syntaxin binding protein 3 2.1234
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 2.1233
KLK6 kallikrein-related peptidase 6 2.123
SCG5 secretogranin V 2.1224
CPT2 carnitine palmitoyltransferase 2 2.12185
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 2.1202
API5 apoptosis inhibitor 5 2.11742
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 2.11503
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 2.115
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 2.1133
PPDPF pancreatic progenitor cell differentiation and proliferation factor 2.1125
PIGT phosphatidylinositol glycan anchor biosynthesis, class T 2.1117
SRR serine racemase 2.1079
SMAD5 SMAD family member 5 2.1057
ARFIP1 ADP-ribosylation factor interacting protein 1 2.1055
IFNGR1 interferon gamma receptor 1 2.1042
ZNF26 zinc finger protein 26 2.103
CPAP centrosome assembly and centriole elongation protein 2.0949
GABARAPL2 GABA(A) receptor-associated protein-like 2 2.0896
CTNND2 catenin (cadherin-associated protein), delta 2 2.0893
KLK8 kallikrein-related peptidase 8 2.0887
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 2.08695
KRT8 keratin 8, type II 2.0835
CDR2L cerebellar degeneration-related protein 2-like 2.0832
STK38L serine/threonine kinase 38 like 2.0823
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 2.0815
METTL1 methyltransferase like 1 2.0812
HOPX HOP homeobox 2.0807
MSL2 male-specific lethal 2 homolog (Drosophila) 2.08
CZIB CXXC motif containing zinc binding protein 2.0784
PPA1 pyrophosphatase (inorganic) 1 2.076
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 2.0752
SATB1 SATB homeobox 1 2.0686
KLK5 kallikrein-related peptidase 5 2.0684
BEGAIN brain-enriched guanylate kinase-associated 2.0655
MAP9 microtubule-associated protein 9 2.0547
MON2 MON2 homolog (S. cerevisiae) 2.05115
KRT10 keratin 10, type I 2.05037
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 2.0485
CH25H cholesterol 25-hydroxylase 2.048
TK2 thymidine kinase 2, mitochondrial 2.04383
KRT1 keratin 1, type II 2.0433
ADORA3 adenosine A3 receptor 2.0417
LGI1 leucine-rich, glioma inactivated 1 2.0396
KCTD11 potassium channel tetramerization domain containing 11 2.039
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 2.0348
CEP290 centrosomal protein 290kDa 2.034
CDH10 cadherin 10, type 2 (T2-cadherin) 2.0335
GAP43 growth associated protein 43 2.0319
ADCY7 adenylate cyclase 7 2.0308
DHCR24 24-dehydrocholesterol reductase 2.03
SEC14L5 SEC14-like 5 (S. cerevisiae) 2.0292
MFSD6 major facilitator superfamily domain containing 6 2.0292
LPP LIM domain containing preferred translocation partner in lipoma 2.0292
TM4SF4 transmembrane 4 L six family member 4 2.0288
CATSPER2 cation channel, sperm associated 2 2.0283
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 2.02315
ERI2 ERI1 exoribonuclease family member 2 2.0226
RAB3D RAB3D, member RAS oncogene family 2.0215
UBE2D1 ubiquitin-conjugating enzyme E2D 1 2.0201
DUSP13A dual specificity phosphatase 13A 2.0194
NOPCHAP1 NOP protein chaperone 1 2.0191
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 2.0187
FBXO34 F-box protein 34 2.0122
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 2.00995
IL13 interleukin 13 2.0094
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.0091
CEP15 centrosomal protein 15 2.0091
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 2.00527
NDC1 NDC1 transmembrane nucleoporin 2.0044
SNX16 sorting nexin 16 2.0039
CYB5R2 cytochrome b5 reductase 2 2.0034
LOC128031832 uncharacterized LOC128031832 2.0007
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B 2.0002

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -10.0
HMG20B high mobility group 20B -9.35975
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -7.634
MLEC malectin -6.37695
SMC1A structural maintenance of chromosomes 1A -5.4853
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -5.0545
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -5.02055
ACAA1 acetyl-CoA acyltransferase 1 -4.9515
RBM34 RNA binding motif protein 34 -4.736
CBR3 carbonyl reductase 3 -4.022
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -3.9075
HOXC10 homeobox C10 -3.9063
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.8416
NGRN neugrin, neurite outgrowth associated -3.7273
KDM5C lysine (K)-specific demethylase 5C -3.722
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 -3.68085
ZC3H15 zinc finger CCCH-type containing 15 -3.59295
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -3.4769
FOXD1 forkhead box D1 -3.4233
THAP11 THAP domain containing 11 -3.3962
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 -3.3037
SCFD1 sec1 family domain containing 1 -3.3029
LOC124905557 eukaryotic translation initiation factor 1A, X-chromosomal -3.2657
SIRPG signal-regulatory protein gamma -3.2308
FOXE1 forkhead box E1 -3.1702
MFSD12 major facilitator superfamily domain containing 12 -3.14415
MTIF2 mitochondrial translational initiation factor 2 -3.1235
CCNC cyclin C -3.1074
PAX9 paired box 9 -3.037
FTSJ3 FtsJ homolog 3 (E. coli) -3.0293
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -3.0274
MAGEA2B melanoma antigen family A2B -3.0146
OFD1 oral-facial-digital syndrome 1 -3.0128
RHOB ras homolog family member B -3.0055
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3) -2.9164
MN1 meningioma (disrupted in balanced translocation) 1 -2.9106
LRRC17 leucine rich repeat containing 17 -2.9011
ACIN1 apoptotic chromatin condensation inducer 1 -2.8849
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -2.8809
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 -2.8712
RNFT1-DT RNFT1 divergent transcript -2.8626
SEH1L SEH1-like (S. cerevisiae) -2.856
RPA3 replication protein A3, 14kDa -2.8512
PPIB peptidylprolyl isomerase B (cyclophilin B) -2.84415
MAP2K1 mitogen-activated protein kinase kinase 1 -2.8188
ANGPTL4 angiopoietin-like 4 -2.8069
LGI2 leucine-rich repeat LGI family, member 2 -2.7648
FNBP1L formin binding protein 1-like -2.7487
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 -2.7092
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 -2.7065
ERP29 endoplasmic reticulum protein 29 -2.6933
SSB Sjogren syndrome antigen B (autoantigen La) -2.6895
C1QBP complement component 1, q subcomponent binding protein -2.6831
BCR breakpoint cluster region -2.6698
CD247 CD247 molecule -2.6336
SQSTM1 sequestosome 1 -2.6242
NGLY1 N-glycanase 1 -2.6059
TRPV4 transient receptor potential cation channel, subfamily V, member 4 -2.6026
GRN granulin -2.5718
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 -2.55547
R3HDM4 R3H domain containing 4 -2.55065
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -2.54235
CCNL2 cyclin L2 -2.5151
HEXB hexosaminidase B (beta polypeptide) -2.5077
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F -2.5009
SNX2 sorting nexin 2 -2.4946
TMPRSS11E transmembrane protease, serine 11E -2.4787
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -2.4187
MFAP2 microfibrillar-associated protein 2 -2.4118
MAGEA1 melanoma antigen family A1 -2.4117
SRSF4 serine/arginine-rich splicing factor 4 -2.4076
LAPTM4A lysosomal protein transmembrane 4 alpha -2.4026
FBXO21 F-box protein 21 -2.40057
RPF1 ribosome production factor 1 homolog (S. cerevisiae) -2.399
RNLS renalase, FAD-dependent amine oxidase -2.3934
ORC3 origin recognition complex, subunit 3 -2.3889
NRIP3 nuclear receptor interacting protein 3 -2.3821
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -2.3739
FNBP4 formin binding protein 4 -2.3708
ITK IL2-inducible T-cell kinase -2.3622
UNC50 unc-50 homolog (C. elegans) -2.3553
YTHDC1 YTH domain containing 1 -2.3421
RWDD1 RWD domain containing 1 -2.3403
PRPF3 pre-mRNA processing factor 3 -2.3288
PRRX2 paired related homeobox 2 -2.3285
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -2.3276
THBS4 thrombospondin 4 -2.3247
FAIM Fas apoptotic inhibitory molecule -2.3206
CACTIN cactin, spliceosome C complex subunit -2.3119
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -2.3108
NUP88 nucleoporin 88kDa -2.31065
MFSD1 major facilitator superfamily domain containing 1 -2.3103
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -2.3056
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) -2.3051
ISCU iron-sulfur cluster assembly enzyme -2.3019
WDR11 WD repeat domain 11 -2.3006
SRPX sushi-repeat containing protein, X-linked -2.2986
HTRA1 HtrA serine peptidase 1 -2.2983
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -2.2943
MTO1 mitochondrial tRNA translation optimization 1 -2.2913
MED15 mediator complex subunit 15 -2.29
CPA4 carboxypeptidase A4 -2.2865
MRNIP MRN complex interacting protein -2.2847
DAD1 defender against cell death 1 -2.2833
USP3 ubiquitin specific peptidase 3 -2.2807
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast) -2.2803
RBM28 RNA binding motif protein 28 -2.2576
TULP4 tubby like protein 4 -2.2507
STEAP1B STEAP family member 1B -2.2496
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -2.24235
ZNF747 zinc finger protein 747 -2.2386
MUTYH mutY homolog -2.2385
S1PR4 sphingosine-1-phosphate receptor 4 -2.2335
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 -2.2307
PRRC2B proline-rich coiled-coil 2B -2.23055
PTPRM protein tyrosine phosphatase, receptor type, M -2.2263
XPC xeroderma pigmentosum, complementation group C -2.215
SERINC1 serine incorporator 1 -2.2124
H1-0 H1.0 linker histone -2.2119
SYF2 SYF2 pre-mRNA-splicing factor -2.2087
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) -2.1995
CD3D CD3d molecule, delta (CD3-TCR complex) -2.1957
FAM168B family with sequence similarity 168, member B -2.1915
S100A1 S100 calcium binding protein A1 -2.1871
RNF13 ring finger protein 13 -2.18095
NAE1 NEDD8 activating enzyme E1 subunit 1 -2.1795
CDK10 cyclin-dependent kinase 10 -2.17923
PRR11 proline rich 11 -2.1752
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 -2.1746
NCKAP1 NCK-associated protein 1 -2.1667
CD164 CD164 molecule, sialomucin -2.15877
AEBP1 AE binding protein 1 -2.1556
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 -2.15155
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 -2.1502
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.1502
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B -2.1502
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 -2.14793
TPSAB1 tryptase alpha/beta 1 -2.14335
YJU2 YJU2 splicing factor homolog -2.1424
ECSIT ECSIT signalling integrator -2.1411
UNC119B unc-119 homolog B (C. elegans) -2.1371
TPST1 tyrosylprotein sulfotransferase 1 -2.1368
RUFY1 RUN and FYVE domain containing 1 -2.1275
GCC2 GRIP and coiled-coil domain containing 2 -2.1235
MAGEA12 melanoma antigen family A12 -2.1201
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae) -2.1199
ABHD14A abhydrolase domain containing 14A -2.1162
FAM13A family with sequence similarity 13, member A -2.11517
PNN pinin, desmosome associated protein -2.1148
ANKMY2 ankyrin repeat and MYND domain containing 2 -2.1127
ATP13A1 ATPase type 13A1 -2.0989
SLBP stem-loop binding protein -2.0944
TMCC2 transmembrane and coiled-coil domain family 2 -2.0902
TMEM87A transmembrane protein 87A -2.0879
SOX15 SRY (sex determining region Y)-box 15 -2.0847
EAPP E2F-associated phosphoprotein -2.0842
ALKBH4 alkB, alkylation repair homolog 4 (E. coli) -2.0842
CORO1C coronin, actin binding protein, 1C -2.081
ICOS inducible T-cell co-stimulator -2.0708
CTSZ cathepsin Z -2.0693
MRPL34 mitochondrial ribosomal protein L34 -2.0688
MAST4 microtubule associated serine/threonine kinase family member 4 -2.06217
PHC1 polyhomeotic homolog 1 (Drosophila) -2.0615
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.0613
ARMC7 armadillo repeat containing 7 -2.0609
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) -2.0607
PCID2 PCI domain containing 2 -2.0588
DAAM2 dishevelled associated activator of morphogenesis 2 -2.0583
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -2.0496
CTSB cathepsin B -2.0494
TFB2M transcription factor B2, mitochondrial -2.0471
LARP7 La ribonucleoprotein domain family, member 7 -2.0469
H2AC7 H2A clustered histone 7 -2.0419
BCL9 B-cell CLL/lymphoma 9 -2.0357
BCAS2 breast carcinoma amplified sequence 2 -2.0317
AQP2 aquaporin 2 (collecting duct) -2.0311
GSTO1 glutathione S-transferase omega 1 -2.0174
KATNA1 katanin p60 (ATPase containing) subunit A 1 -2.0171
CDC50A cell division cycle 50 P4-ATPase accessory subunit A -2.0164
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -2.0159
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -2.0151
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.015
UXS1 UDP-glucuronate decarboxylase 1 -2.0143
LOC124907012 endogenous retrovirus group K member 7 Env polyprotein-like -2.0074
RBM10 RNA binding motif protein 10 -2.00497
TLE5 TLE family member 5, transcriptional modulator -2.0036
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.0036
CYFIP1 cytoplasmic FMR1 interacting protein 1 -2.0021
CRTC3 CREB regulated transcription coactivator 3 -2.0017