CREB1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description cAMP responsive element binding protein 1|This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1385)
External Link http://www.ncbi.nlm.nih.gov/gene/1385
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171 interacting proteins for CREB1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ATF1 activating transcription factor 1
ATF6 activating transcription factor 6
ATF7 activating transcription factor 7
ATF7IP activating transcription factor 7 interacting protein
ATG13 autophagy related 13
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
ATXN3 ataxin 3
BRCA1 breast cancer 1, early onset
C14ORF1 chromosome 14 open reading frame 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARM1 coactivator-associated arginine methyltransferase 1
CCDC6 coiled-coil domain containing 6
CDC37 cell division cycle 37
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHD3 chromodomain helicase DNA binding protein 3
CHD8 chromodomain helicase DNA binding protein 8
CREBBP CREB binding protein
CREM cAMP responsive element modulator
CRTC1 CREB regulated transcription coactivator 1
CRTC2 CREB regulated transcription coactivator 2
CSNK1A1 casein kinase 1, alpha 1
CSNK1D casein kinase 1, delta
CSNK2A1 casein kinase 2, alpha 1 polypeptide
DACH1 dachshund family transcription factor 1
DAXX death-domain associated protein
DEAF1 DEAF1 transcription factor
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDF1 endothelial differentiation-related factor 1
EP300 E1A binding protein p300
FHL2 four and a half LIM domains 2
FHL3 four and a half LIM domains 3
FHL5 four and a half LIM domains 5
FLNA filamin A, alpha
GDNF glial cell derived neurotrophic factor
GFRA1 GDNF family receptor alpha 1
GLDC glycine dehydrogenase (decarboxylating)
GLI2 GLI family zinc finger 2
GLRX3 glutaredoxin 3
GRB2 growth factor receptor-bound protein 2
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HBS1L HBS1-like translational GTPase
HDAC1 histone deacetylase 1
HDAC2 histone deacetylase 2
HDAC8 histone deacetylase 8
HIPK2 homeodomain interacting protein kinase 2
HIPK3 homeodomain interacting protein kinase 3
HIST1H3B histone cluster 1, H3b
HNF1B HNF1 homeobox B
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HPS6 Hermansky-Pudlak syndrome 6
ILK integrin-linked kinase
IPO9 importin 9
JUN jun proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KCNIP3 Kv channel interacting protein 3, calsenilin
KIAA2026 KIAA2026
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MAX MYC associated factor X
MED15 mediator complex subunit 15
MEIS1 Meis homeobox 1
MFAP1 microfibrillar-associated protein 1
MTA2 metastasis associated 1 family, member 2
MTF2 metal response element binding transcription factor 2
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYOD1 myogenic differentiation 1
NCOR1 nuclear receptor corepressor 1
NFIL3 nuclear factor, interleukin 3 regulated
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRF1 nuclear respiratory factor 1
OBSL1 obscurin-like 1
PASK PAS domain containing serine/threonine kinase
PBX1 pre-B-cell leukemia homeobox 1
PDX1 pancreatic and duodenal homeobox 1
PIAS1 protein inhibitor of activated STAT, 1
PLCG1 phospholipase C, gamma 1
PLK1 polo-like kinase 1
POGZ pogo transposable element with ZNF domain
POU2F1 POU class 2 homeobox 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2R2D protein phosphatase 2, regulatory subunit B, delta
PPP5C protein phosphatase 5, catalytic subunit
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKCE protein kinase C, epsilon
PRKD1 protein kinase D1
PRKG1 protein kinase, cGMP-dependent, type I
PYCRL pyrroline-5-carboxylate reductase-like
RAB1A RAB1A, member RAS oncogene family
RB1CC1 RB1-inducible coiled-coil 1
RBBP4 retinoblastoma binding protein 4
RECQL5 RecQ protein-like 5
RET ret proto-oncogene
RFX3 regulatory factor X, 3 (influences HLA class II expression)
RGS13 regulator of G-protein signaling 13
RNF111 ring finger protein 111
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SGK1 serum/glucocorticoid regulated kinase 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIRT1 sirtuin 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SNW1 SNW domain containing 1
SOS1 son of sevenless homolog 1 (Drosophila)
SOX9 SRY (sex determining region Y)-box 9
SRA1 steroid receptor RNA activator 1
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SRF serum response factor (c-fos serum response element-binding transcription factor)
SSBP3 single stranded DNA binding protein 3
SUMO1 small ubiquitin-like modifier 1
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
THRA thyroid hormone receptor, alpha
TOX4 TOX high mobility group box family member 4
TP53 tumor protein p53
TRIM22 tripartite motif containing 22
TSSK4 testis-specific serine kinase 4
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I
ULK2 unc-51 like autophagy activating kinase 2
VIM vimentin
WDR26 WD repeat domain 26
WDR6 WD repeat domain 6
YAP1 Yes-associated protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YY1 YY1 transcription factor
ZHX1 zinc fingers and homeoboxes 1
ZMYM2 zinc finger, MYM-type 2
ZNF35 zinc finger protein 35
ZNF436 zinc finger protein 436
ZNF451 zinc finger protein 451
ZNF92 zinc finger protein 92