CREBBP Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description CREB binding protein|This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009] (NCBI Entrez Gene Database, 1387)
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Genes

517 genes differentially expressed following the CREBBP gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
NPR3 natriuretic peptide receptor 3 3.34461
TAS1R1 taste receptor, type 1, member 1 3.34461
GRAP2 GRB2-related adaptor protein 2 3.34461
OAZ3 ornithine decarboxylase antizyme 3 3.34461
ZBED6 zinc finger, BED-type containing 6 3.34461
ASPA aspartoacylase 3.34461
GC group-specific component (vitamin D binding protein) 3.34461
RAB44 RAB44, member RAS oncogene family 3.34461
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 3.34461
PAX3 paired box 3 3.34461
RNF224 ring finger protein 224 3.34461
ITGB7 integrin, beta 7 3.34461
FNDC1 fibronectin type III domain containing 1 3.34461
GIPC3 GIPC PDZ domain containing family, member 3 3.34461
VWA3A von Willebrand factor A domain containing 3A 3.34461
SYT15B synaptotagmin 15B 3.34461
LPA lipoprotein, Lp(a) 3.34461
GMNC geminin coiled-coil domain containing 3.34461
LEF1 lymphoid enhancer-binding factor 1 3.34461
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 3.34461
FXYD3 FXYD domain containing ion transport regulator 3 3.34461
DNAH10 dynein, axonemal, heavy chain 10 3.34461
CLRN2 clarin 2 3.34461
BCO1 beta-carotene oxygenase 1 3.34461
CCDC83 coiled-coil domain containing 83 3.34461
HAP1 huntingtin-associated protein 1 3.34461
GPR26 G protein-coupled receptor 26 3.30069
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 3.30069
PI16 peptidase inhibitor 16 3.30069
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 3.30069
TRH thyrotropin-releasing hormone 3.30069
IGFL4 IGF-like family member 4 3.30069
CELF6 CUGBP, Elav-like family member 6 3.30069
NXPH3 neurexophilin 3 3.30069
IL17B interleukin 17B 3.30069
TBX15 T-box 15 3.30069
ADTRP androgen-dependent TFPI-regulating protein 3.30069
SH2D6 SH2 domain containing 6 3.30069
FOXR1 forkhead box R1 3.30069
ZACN zinc activated ligand-gated ion channel 3.30069
CELA3A chymotrypsin-like elastase family, member 3A 3.30069
PTGFR prostaglandin F receptor (FP) 3.30069
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 3.30069
OIT3 oncoprotein induced transcript 3 3.30069
OR2AJ1 olfactory receptor, family 2, subfamily AJ, member 1 3.30069
NMUR2 neuromedin U receptor 2 3.30069
KIAA1755 KIAA1755 3.30069
ERAP2 endoplasmic reticulum aminopeptidase 2 3.30069
RNASE9 ribonuclease, RNase A family, 9 (non-active) 3.30069
PCDHGA12 protocadherin gamma subfamily A, 12 3.30069
MNX1 motor neuron and pancreas homeobox 1 3.30069
VPREB3 pre-B lymphocyte 3 3.30069
ASCL1 achaete-scute family bHLH transcription factor 1 3.30069
TSHZ1 teashirt zinc finger homeobox 1 3.30069
DIO3 deiodinase, iodothyronine, type III 3.30069
ATOH7 atonal homolog 7 (Drosophila) 3.30069
TRPV5 transient receptor potential cation channel, subfamily V, member 5 3.30069
RAPSN receptor-associated protein of the synapse 3.30069
TPSD1 tryptase delta 1 3.30069
HBZ hemoglobin, zeta 3.30069
CPB1 carboxypeptidase B1 (tissue) 3.30069
ACVRL1 activin A receptor type II-like 1 3.30069
DLL4 delta-like 4 (Drosophila) 3.30069
PNLIPRP2 pancreatic lipase-related protein 2 3.30069
GNG13 guanine nucleotide binding protein (G protein), gamma 13 3.30069
ATOH8 atonal homolog 8 (Drosophila) 3.30069
NLRP6 NLR family, pyrin domain containing 6 3.30069
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 3.30069
CPNE8-AS1 CPNE8 antisense RNA 1 3.30069
TYROBP TYRO protein tyrosine kinase binding protein 3.30069
RAX2 retina and anterior neural fold homeobox 2 3.30069
PNLIPRP1 pancreatic lipase-related protein 1 3.30069
TRPC7 transient receptor potential cation channel, subfamily C, member 7 3.30069
LY6K lymphocyte antigen 6 complex, locus K 3.30069
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic 3.30069
ARL14EPL ADP-ribosylation factor-like 14 effector protein-like 3.30069
NDP Norrie disease (pseudoglioma) 3.30069
CCDC42 coiled-coil domain containing 42 3.30069
DLK1 delta-like 1 homolog (Drosophila) 3.30069
GPX5 glutathione peroxidase 5 3.30069
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 3.30069
SEPTIN14 septin 14 3.30069
PRRT1B proline rich transmembrane protein 1B 3.30069
MDFIC2 MyoD family inhibitor domain containing 2 3.30069
H3-7 H3.7 histone (putative) 3.30069
DNAAF6 dynein axonemal assembly factor 6 3.30069
TENT5D terminal nucleotidyltransferase 5D 3.30069
PLPP4 phospholipid phosphatase 4 3.30069
CALHM5 calcium homeostasis modulator family member 5 3.30069
TLE7 TLE family member 7 3.30069
PHF24 PHD finger protein 24 3.30069
IRAG2 inositol 1,4,5-triphosphate receptor associated 2 3.30069
BEST3 bestrophin 3 3.30069
LGSN lengsin, lens protein with glutamine synthetase domain 3.30069
GDF6 growth differentiation factor 6 3.30069
MAGEB3 melanoma antigen family B3 3.30069
PRB2 proline-rich protein BstNI subfamily 2 3.30069
ACTL10 actin-like 10 3.30069
SRPX2 sushi-repeat containing protein, X-linked 2 3.30069
RNF17 ring finger protein 17 3.30069
ZNF726 zinc finger protein 726 3.30069
NAPSA napsin A aspartic peptidase 3.30069
MYO7B myosin VIIB 3.30069
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 3.30069
ZNF503 zinc finger protein 503 3.30069
CD48 CD48 molecule 3.30069
IL6 interleukin 6 3.30069
IL4 interleukin 4 3.30069
GPR83 G protein-coupled receptor 83 3.30069
VCX3A variable charge, X-linked 3A 3.30069
CCR9 chemokine (C-C motif) receptor 9 3.30069
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 3.30069
PIWIL1 piwi-like RNA-mediated gene silencing 1 3.30069
C1QL4 complement component 1, q subcomponent-like 4 3.30069
LOC124901449 uncharacterized LOC124901449 3.30069
SLAMF1 signaling lymphocytic activation molecule family member 1 3.30069
SH3TC2 SH3 domain and tetratricopeptide repeats 2 3.30069
TFEC transcription factor EC 3.30069
ZNF492 zinc finger protein 492 3.30069
TEKT1 tektin 1 3.30069
IL17REL interleukin 17 receptor E-like 3.30069
DMRT3 doublesex and mab-3 related transcription factor 3 3.30069
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 3.30069
MORC1 MORC family CW-type zinc finger 1 3.30069
OR6X1 olfactory receptor, family 6, subfamily X, member 1 3.30069
BTG4 B-cell translocation gene 4 3.30069
DYTN dystrotelin 3.30069
CALHM3 calcium homeostasis modulator 3 3.30069
DLX5 distal-less homeobox 5 3.30069
TMIGD2 transmembrane and immunoglobulin domain containing 2 3.30069
PRR15L proline rich 15-like 3.30069
RGR retinal G protein coupled receptor 3.30069
CCNI2 cyclin I family, member 2 3.30069
MST1 macrophage stimulating 1 3.30069
CLEC1A C-type lectin domain family 1, member A 3.30069
MYLK2 myosin light chain kinase 2 3.30069
LRRC46 leucine rich repeat containing 46 3.30069
RSAD2 radical S-adenosyl methionine domain containing 2 3.30069
CLIC3 chloride intracellular channel 3 3.30069
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 3.30069
ILDR2 immunoglobulin-like domain containing receptor 2 3.30069
CCDC27 coiled-coil domain containing 27 3.30069
CHIT1 chitinase 1 (chitotriosidase) 3.30069
HKDC1 hexokinase domain containing 1 3.30069
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 3.30069
ITGA10 integrin, alpha 10 3.30069
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 3.30069
KLF1 Kruppel-like factor 1 (erythroid) 3.30069
PIP prolactin-induced protein 3.30069
NOX1 NADPH oxidase 1 3.30069
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 3.30069
BTNL3 butyrophilin-like 3 3.30069
ADGRA1 adhesion G protein-coupled receptor A1 3.30069
GP5 glycoprotein V (platelet) 3.30069
ERICH3 glutamate-rich 3 3.30069
OR14A16 olfactory receptor, family 14, subfamily A, member 16 3.30069
LAMB4 laminin, beta 4 3.30069
TMPRSS15 transmembrane protease, serine 15 3.30069
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 3.30069
RIIAD1 regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1 3.30069
THEM5 thioesterase superfamily member 5 3.30069
GRAPL GRB2-related adaptor protein-like 3.30069
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 3.30069
GOLGA8N golgin A8 family, member N 3.30069
LAMP5 lysosomal-associated membrane protein family, member 5 3.30069
TGM3 transglutaminase 3 3.30069
APOL6 apolipoprotein L, 6 3.30069
AMDHD1 amidohydrolase domain containing 1 3.30069
APOL1 apolipoprotein L, 1 3.30069
ANGPTL5 angiopoietin-like 5 3.30069
PLA2G5 phospholipase A2, group V 3.30069
GOLGA8K golgin A8 family, member K 3.30069
SLC38A11 solute carrier family 38, member 11 3.30069
UPK1A uroplakin 1A 3.30069
VXN vexin 3.2586
MYH2 myosin, heavy chain 2, skeletal muscle, adult 3.2586
MR1 major histocompatibility complex, class I-related 3.2586
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 3.2586
HMGN2 high mobility group nucleosomal binding domain 2 3.19665
KISS1 KiSS-1 metastasis-suppressor 3.17706
PDHX pyruvate dehydrogenase complex, component X 3.07971
ATAT1 alpha tubulin acetyltransferase 1 3.07971
GSTO1 glutathione S-transferase omega 1 3.07405
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 3.04431
GNG5 guanine nucleotide binding protein (G protein), gamma 5 3.01782
HINT1 histidine triad nucleotide binding protein 1 3.01782
PCDH12 protocadherin 12 2.93339
PON2 paraoxonase 2 2.92759
TIMCC TIM double twin CX3C motif chaperone 2.89356
KLHL15 kelch-like family member 15 2.88863
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 2.8148
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 2.73586
LEFTY1 left-right determination factor 1 2.69225
TRABD2A TraB domain containing 2A 2.66907
ADI1 acireductone dioxygenase 1 2.66907
UCK2 uridine-cytidine kinase 2 2.65787
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 2.64251
EHMT2 euchromatic histone-lysine N-methyltransferase 2 2.63526
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) 2.62321
GNS glucosamine (N-acetyl)-6-sulfatase 2.62321
FRS3 fibroblast growth factor receptor substrate 3 2.61794
FHIP2B FHF complex subunit HOOK interacting protein 2B 2.61794
ACAT2 acetyl-CoA acetyltransferase 2 2.57009
DBP D site of albumin promoter (albumin D-box) binding protein 2.55349
C7ORF25 chromosome 7 open reading frame 25 2.55071
OPRM1 opioid receptor, mu 1 2.55071
PDF peptide deformylase (mitochondrial) 2.55071
TMEM63A transmembrane protein 63A 2.52154
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 2.49322
PTTG1 pituitary tumor-transforming 1 2.48417
SCAMP1 secretory carrier membrane protein 1 2.47951
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 2.47859
MRPL12 mitochondrial ribosomal protein L12 2.47092
ARHGAP19 Rho GTPase activating protein 19 2.45886
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 2.45856
COA8 cytochrome c oxidase assembly factor 8 2.45669
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 2.45669
JPT2 Jupiter microtubule associated homolog 2 2.44006
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 2.43624
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 2.43298
PEBP4 phosphatidylethanolamine-binding protein 4 2.43298
CPO carboxypeptidase O 2.43298
DTX3 deltex 3, E3 ubiquitin ligase 2.42867
IMPG1 interphotoreceptor matrix proteoglycan 1 2.42854
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 2.42854
MDGA1 MAM domain containing glycosylphosphatidylinositol anchor 1 2.42854
CFAP100 cilia and flagella associated protein 100 2.42854
MMRN2 multimerin 2 2.42854
PLA2G10 phospholipase A2, group X 2.42854
PVALEF parvalbumin like EF-hand containing 2.42854
FAM133B family with sequence similarity 133, member B 2.42612
DTWD2 DTW domain containing 2 2.41898
SYT11 synaptotagmin XI 2.41506
PITPNB phosphatidylinositol transfer protein, beta 2.41303
KIF27 kinesin family member 27 2.4039
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit 2.40342
USPL1 ubiquitin specific peptidase like 1 2.40342
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 2.40342
GOLT1B golgi transport 1B 2.40342
SYCE1L synaptonemal complex central element protein 1-like 2.39879
MYO6 myosin VI 2.39357
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 2.36163
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 2.36163
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 2.35967
NME4 NME/NM23 nucleoside diphosphate kinase 4 2.34646
PYGL phosphorylase, glycogen, liver 2.34646
SLC39A6 solute carrier family 39 (zinc transporter), member 6 2.3433
TKFC triokinase/FMN cyclase 2.3433
CARNMT1 carnosine N-methyltransferase 1 2.3433
TMEM38A transmembrane protein 38A 2.34066
UBXN2B UBX domain protein 2B 2.34066
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2 2.33507
GGT7 gamma-glutamyltransferase 7 2.32185
CHP2 calcineurin-like EF-hand protein 2 2.32014
DERA deoxyribose-phosphate aldolase (putative) 2.28279
THOC3 THO complex 3 2.28141
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 2.27977
CCDC181 coiled-coil domain containing 181 2.27922
BCL10 B-cell CLL/lymphoma 10 2.25369
FJX1 four jointed box 1 (Drosophila) 2.25099
TUG1 taurine up-regulated 1 (non-protein coding) 2.24508
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 2.24479
CENPV centromere protein V 2.24229
EEIG2 EEIG family member 2 2.23801
ZDHHC18 zinc finger, DHHC-type containing 18 2.23801
SURF6 surfeit 6 2.23325
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 2.22965
PYGO2 pygopus family PHD finger 2 2.22215
ADISSP adipose secreted signaling protein 2.22117
PXN paxillin 2.21699
PURB purine-rich element binding protein B 2.21434
ARMCX5 armadillo repeat containing, X-linked 5 2.21391
SSR1 signal sequence receptor, alpha 2.21367
IFTAP intraflagellar transport associated protein 2.20594
PPOX protoporphyrinogen oxidase 2.18863
CTXN1 cortexin 1 2.18276
VEGFC vascular endothelial growth factor C 2.18128
FUCA1 fucosidase, alpha-L- 1, tissue 2.17252
APOB apolipoprotein B 2.1671
MIDN midnolin 2.15584
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 2.15343
TIGD4 tigger transposable element derived 4 2.15343
ZDHHC20 zinc finger, DHHC-type containing 20 2.15343
ZNF695 zinc finger protein 695 2.13512
EXOSC2 exosome component 2 2.13295
RPAIN RPA interacting protein 2.1327
MRTO4 mRNA turnover 4 homolog (S. cerevisiae) 2.12335
JOSD1 Josephin domain containing 1 2.11892
RITA1 RBPJ interacting and tubulin associated 1 2.11741
MEGF8 multiple EGF-like-domains 8 2.11358
H3-3B H3.3 histone B 2.10223
TRIM8 tripartite motif containing 8 2.10223
SGO1 shugoshin 1 2.10214
API5 apoptosis inhibitor 5 2.10214
MOSPD2 motile sperm domain containing 2 2.09884
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.08507
ABITRAM actin binding transcription modulator 2.08507
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 2.0837
ABRAXAS1 abraxas 1, BRCA1 A complex subunit 2.08013
MPDU1 mannose-P-dolichol utilization defect 1 2.0771
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 2.07307
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.07173
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 2.06639
LTO1 LTO1 maturation factor of ABCE1 2.06639
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived) 2.06639
BEX3 brain expressed X-linked 3 2.06639
CAPN3 calpain 3, (p94) 2.05871
CORT cortistatin 2.05871
SLIRP SRA stem-loop interacting RNA binding protein 2.05725
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 2.05458
KRTDAP keratinocyte differentiation-associated protein 2.05216
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 2.04962
SPAG9 sperm associated antigen 9 2.04962
ERCC5 excision repair cross-complementation group 5 2.04397
RNF185 ring finger protein 185 2.0352
CLDN1 claudin 1 2.03234
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 2.02846
RAB29 RAB29, member RAS oncogene family 2.0248
ZNF154 zinc finger protein 154 2.02251
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 2.01828
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 2.00604

decreased expression

Symbol Name Standardized Value
FOXO1 forkhead box O1 -3.34461
PI15 peptidase inhibitor 15 -3.30069
CNTNAP4 contactin associated protein-like 4 -3.30069
MUC16 mucin 16, cell surface associated -3.30069
ZNF385B zinc finger protein 385B -3.30069
PCDHGA6 protocadherin gamma subfamily A, 6 -3.30069
SYNDIG1 synapse differentiation inducing 1 -3.30069
AMPH amphiphysin -3.30069
DIAPH2 diaphanous-related formin 2 -3.30069
CDK3 cyclin-dependent kinase 3 -3.30069
ERFE erythroferrone -3.30069
ROR1 receptor tyrosine kinase-like orphan receptor 1 -3.30069
CREBBP CREB binding protein -3.22544
TCL1B T-cell leukemia/lymphoma 1B -3.20418
LOXL4 lysyl oxidase-like 4 -3.19665
MS4A12 membrane-spanning 4-domains, subfamily A, member 12 -3.19665
GLYATL1B glycine-N-acyltransferase like 1B -3.19665
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C -3.19665
KCTD4 potassium channel tetramerization domain containing 4 -3.19665
PF4V1 platelet factor 4 variant 1 -3.19665
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1 -3.19665
SP100 SP100 nuclear antigen -3.19665
OR1B1 olfactory receptor, family 1, subfamily B, member 1 (gene/pseudogene) -3.19665
SLC10A6 solute carrier family 10 (sodium/bile acid cotransporter), member 6 -3.19665
PODNL1 podocan-like 1 -3.19665
OVCH1 ovochymase 1 -3.19665
FAM107A family with sequence similarity 107, member A -3.19665
CCR6 chemokine (C-C motif) receptor 6 -3.19665
CLDN5 claudin 5 -3.19665
FOXD1 forkhead box D1 -3.19665
ZNF98 zinc finger protein 98 -3.19665
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z -3.19665
GJA9 gap junction protein, alpha 9, 59kDa -3.19665
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 -3.19665
SCGN secretagogin, EF-hand calcium binding protein -3.19665
FOXA2 forkhead box A2 -3.19665
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -3.19665
GLRA3 glycine receptor, alpha 3 -3.19665
LOC124902436 talanin -3.19665
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) -3.19665
KLK6 kallikrein-related peptidase 6 -3.19665
GPR12 G protein-coupled receptor 12 -3.19665
INSM1 insulinoma-associated 1 -3.19665
CXCR2 chemokine (C-X-C motif) receptor 2 -3.19665
AQP4 aquaporin 4 -3.19665
ARR3 arrestin 3, retinal (X-arrestin) -3.19665
LCN2 lipocalin 2 -3.19665
ITGA11 integrin, alpha 11 -3.19665
CCDC170 coiled-coil domain containing 170 -3.19665
EFCAB8 EF-hand calcium binding domain 8 -3.19665
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion -3.19665
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -3.19665
SOBP sine oculis binding protein homolog (Drosophila) -3.17706
SYNE1 spectrin repeat containing, nuclear envelope 1 -3.11638
FSD2 fibronectin type III and SPRY domain containing 2 -3.08793
IFI6 interferon, alpha-inducible protein 6 -3.08793
RAI14 retinoic acid induced 14 -2.93968
TECR trans-2,3-enoyl-CoA reductase -2.93127
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -2.91491
NLGN4X neuroligin 4, X-linked -2.90026
CCDC159 coiled-coil domain containing 159 -2.89353
HMBS hydroxymethylbilane synthase -2.84964
FAM78B family with sequence similarity 78, member B -2.83349
NPIPB13 nuclear pore complex interacting protein family, member B13 -2.79569
GJA1 gap junction protein, alpha 1, 43kDa -2.77606
FBXL7 F-box and leucine-rich repeat protein 7 -2.74627
MEI4 meiosis-specific 4 homolog (S. cerevisiae) -2.74364
UGP2 UDP-glucose pyrophosphorylase 2 -2.73547
GALNT17 polypeptide N-acetylgalactosaminyltransferase 17 -2.73547
PLPP1 phospholipid phosphatase 1 -2.73547
FRAS1 Fraser extracellular matrix complex subunit 1 -2.68301
C11ORF68 chromosome 11 open reading frame 68 -2.64735
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.64251
EYS eyes shut homolog (Drosophila) -2.64251
INTS12 integrator complex subunit 12 -2.62279
PNP purine nucleoside phosphorylase -2.61648
SOX4 SRY (sex determining region Y)-box 4 -2.61648
GPRIN1 G protein regulated inducer of neurite outgrowth 1 -2.6157
STRBP spermatid perinuclear RNA binding protein -2.58839
FAM169A family with sequence similarity 169, member A -2.58694
CC2D2B coiled-coil and C2 domain containing 2B -2.55071
LRFN3 leucine rich repeat and fibronectin type III domain containing 3 -2.52154
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 -2.52154
UNC5C unc-5 homolog C (C. elegans) -2.49879
C6ORF163 chromosome 6 open reading frame 163 -2.49533
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide -2.49533
DNAL1 dynein, axonemal, light chain 1 -2.48084
DLG2 discs, large homolog 2 (Drosophila) -2.47951
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 -2.47092
SYNGR3 synaptogyrin 3 -2.47092
STIM2 stromal interaction molecule 2 -2.47092
RUNX1 runt-related transcription factor 1 -2.46654
FLT1 fms-related tyrosine kinase 1 -2.45856
ZNF546 zinc finger protein 546 -2.45784
SLC39A11 solute carrier family 39, member 11 -2.45669
FLT3LG fms-related tyrosine kinase 3 ligand -2.43298
BEST2 bestrophin 2 -2.42867
KMT5C lysine methyltransferase 5C -2.42854
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A -2.41898
RORA RAR-related orphan receptor A -2.41506
LRRC4C leucine rich repeat containing 4C -2.41506
PES1 pescadillo ribosomal biogenesis factor 1 -2.39739
FKBP5 FK506 binding protein 5 -2.39739
C2CD2 C2 calcium-dependent domain containing 2 -2.39543
ZNF692 zinc finger protein 692 -2.39357
C4ORF33 chromosome 4 open reading frame 33 -2.39185
RRM2B ribonucleotide reductase M2 B (TP53 inducible) -2.34646
FANCC Fanconi anemia, complementation group C -2.34646
AAAS achalasia, adrenocortical insufficiency, alacrimia -2.3433
SOCS1 suppressor of cytokine signaling 1 -2.3433
DOCK2 dedicator of cytokinesis 2 -2.3433
THY1 Thy-1 cell surface antigen -2.33576
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III -2.33507
SHISAL2A shisa like 2A -2.31854
HYAL1 hyaluronoglucosaminidase 1 -2.30227
TMEM106C transmembrane protein 106C -2.29191
DOCK5 dedicator of cytokinesis 5 -2.28714
STXBP1 syntaxin binding protein 1 -2.27922
LRRC1 leucine rich repeat containing 1 -2.26749
DCAF17 DDB1 and CUL4 associated factor 17 -2.26244
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2 -2.24814
ANKRD6 ankyrin repeat domain 6 -2.24479
CNGA4 cyclic nucleotide gated channel alpha 4 -2.24479
H4C9 H4 clustered histone 9 -2.24479
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 -2.24479
SLC49A4 solute carrier family 49 member 4 -2.24479
ZFP36L1 ZFP36 ring finger protein-like 1 -2.24479
PCDH11X protocadherin 11 X-linked -2.24479
NKAP NFKB activating protein -2.24271
VANGL2 VANGL planar cell polarity protein 2 -2.24231
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) -2.24229
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -2.24229
IL17C interleukin 17C -2.23801
MAP6 microtubule-associated protein 6 -2.23801
MT1F metallothionein 1F -2.23801
SHISA9 shisa family member 9 -2.23325
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.23325
GPAA1 glycosylphosphatidylinositol anchor attachment 1 -2.23325
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein -2.23325
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase -2.22215
CADM4 cell adhesion molecule 4 -2.22201
RHCE Rh blood group, CcEe antigens -2.22201
SETD1B SET domain containing 1B -2.22
TNIP1 TNFAIP3 interacting protein 1 -2.21951
PCNX1 pecanex 1 -2.20768
USP43 ubiquitin specific peptidase 43 -2.20594
SENP6 SUMO1/sentrin specific peptidase 6 -2.20331
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 -2.19432
SULF2 sulfatase 2 -2.18863
SNX2 sorting nexin 2 -2.18823
SSBP3 single stranded DNA binding protein 3 -2.18128
TMEM190 transmembrane protein 190 -2.16237
C19ORF38 chromosome 19 open reading frame 38 -2.16237
ZWILCH zwilch kinetochore protein -2.15343
SIK3 SIK family kinase 3 -2.15343
SPDYE17 speedy/RINGO cell cycle regulator family member E17 -2.15343
PHF21B PHD finger protein 21B -2.15343
TM6SF1 transmembrane 6 superfamily member 1 -2.15343
TRPC5 transient receptor potential cation channel, subfamily C, member 5 -2.15091
CPEB3 cytoplasmic polyadenylation element binding protein 3 -2.15062
INAFM2 InaF-motif containing 2 -2.14283
MB21D2 Mab-21 domain containing 2 -2.13871
SMIM14 small integral membrane protein 14 -2.13295
ACP6 acid phosphatase 6, lysophosphatidic -2.12834
TMEM108 transmembrane protein 108 -2.12279
DHRS7B dehydrogenase/reductase (SDR family) member 7B -2.1156
TYRO3 TYRO3 protein tyrosine kinase -2.10214
ENTREP2 endosomal transmembrane epsin interactor 2 -2.09982
CLMP CXADR-like membrane protein -2.09234
VGF VGF nerve growth factor inducible -2.09234
DSCAM Down syndrome cell adhesion molecule -2.08507
FGFR3 fibroblast growth factor receptor 3 -2.08507
PRKCSH protein kinase C substrate 80K-H -2.08507
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 -2.08423
IRF1 interferon regulatory factor 1 -2.08361
DGKQ diacylglycerol kinase, theta 110kDa -2.06639
TCF4 transcription factor 4 -2.06639
WDR13 WD repeat domain 13 -2.06639
AXIN1 axin 1 -2.06639
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) -2.06639
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B -2.06607
RGS5 regulator of G-protein signaling 5 -2.0578
MRPS34 mitochondrial ribosomal protein S34 -2.04699
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5 -2.03395
MEGF6 multiple EGF-like-domains 6 -2.03054
SPRYD7 SPRY domain containing 7 -2.02985
PFAS phosphoribosylformylglycinamidine synthase -2.02545
CDK14 cyclin-dependent kinase 14 -2.02317
TCN2 transcobalamin II -2.0231
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 -2.02251
ZFHX4 zinc finger homeobox 4 -2.01151
MMP15 matrix metallopeptidase 15 (membrane-inserted) -2.00976
CHIC1 cysteine-rich hydrophobic domain 1 -2.00817
ARID4A AT rich interactive domain 4A (RBP1-like) -2.00604
PPP2R2B protein phosphatase 2, regulatory subunit B, beta -2.00434
XYLT1 xylosyltransferase I -2.00041