| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | CREB binding protein|This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009] (NCBI Entrez Gene Database, 1387) |
| External Link | https://ncbi.nlm.nih.gov/gene/1387 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the CREBBP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LTF | lactotransferrin | 0.0147403 |
| EGR1 | early growth response 1 | 0.013118 |
| SEPP1 | selenoprotein P, plasma, 1 | 0.0130655 |
| XIC | X chromosome inactivation center | 0.0117655 |
| SIRT3 | sirtuin 3 | 0.0117619 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.0105895 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0105386 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0103528 |
| BEX1 | brain expressed, X-linked 1 | 0.0100707 |
| REEP1 | receptor accessory protein 1 | 0.00986466 |
| CENPE | centromere protein E, 312kDa | 0.0094959 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.00923896 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00916896 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00898755 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.00891323 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00865367 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00864332 |
| MPO | myeloperoxidase | 0.00823706 |
| PEG10 | paternally expressed 10 | 0.00810734 |
| GOLGA8A | golgin A8 family, member A | 0.00798459 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.00782908 |
| OAT | ornithine aminotransferase | 0.00778025 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00776801 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00776697 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00763393 |
| PTHLH | parathyroid hormone-like hormone | 0.00748659 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.00740443 |
| COCH | cochlin | 0.00738463 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | 0.00734357 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00718239 |
| AZU1 | azurocidin 1 | 0.00713501 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.00712949 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | 0.00708752 |
| TOM1L1 | target of myb1 (chicken)-like 1 | 0.00706892 |
| EPCAM | epithelial cell adhesion molecule | 0.00705711 |
| MATN2 | matrilin 2 | 0.00704517 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 | 0.00702443 |
| CA2 | carbonic anhydrase II | 0.0070212 |
| ODC1 | ornithine decarboxylase 1 | 0.00702089 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00700562 |
| ELANE | elastase, neutrophil expressed | 0.00695439 |
| NRIP3 | nuclear receptor interacting protein 3 | 0.0069238 |
| CAMP | cathelicidin antimicrobial peptide | 0.00692184 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00692181 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00690767 |
| GOLT1B | golgi transport 1B | 0.0069066 |
| BPI | bactericidal/permeability-increasing protein | 0.00688787 |
| ENPP4 | ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) | 0.00682844 |
| RAB40B | RAB40B, member RAS oncogene family | 0.00680458 |
| SSR4 | signal sequence receptor, delta | 0.00678762 |
| C12ORF4 | chromosome 12 open reading frame 4 | 0.00676995 |
| NEFH | neurofilament, heavy polypeptide | 0.00668159 |
| DLX2 | distal-less homeobox 2 | 0.00668129 |
| NEFM | neurofilament, medium polypeptide | 0.00667705 |
| GNAS | GNAS complex locus | 0.00664792 |
| MOSPD1 | motile sperm domain containing 1 | 0.00663132 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00657642 |
| ZNF91 | zinc finger protein 91 | 0.00649319 |
| MSX1 | msh homeobox 1 | 0.00644587 |
| NCAPG | non-SMC condensin I complex, subunit G | 0.00637661 |
| ARG1 | arginase 1 | 0.00631598 |
| HSPA4L | heat shock 70kDa protein 4-like | 0.00631426 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00629361 |
| NUCB2 | nucleobindin 2 | 0.00629092 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0062693 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.00626105 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | 0.0062277 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.0062244 |
| BBX | bobby sox homolog (Drosophila) | 0.00618532 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.00616759 |
| PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.006151 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.0061496 |
| JUNB | jun B proto-oncogene | 0.00614454 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | 0.0061424 |
| CCNE2 | cyclin E2 | 0.0061029 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00608633 |
| HOXC6 | homeobox C6 | 0.00605797 |
| SAR1B | secretion associated, Ras related GTPase 1B | 0.00605565 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 0.00604578 |
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble | 0.00603115 |
| WLS | wntless Wnt ligand secretion mediator | 0.00601574 |
| MARCHF5 | membrane associated ring-CH-type finger 5 | 0.00600916 |
| OGA | O-GlcNAcase | 0.00596465 |
| BSG | basigin (Ok blood group) | 0.00593363 |
| CCND2 | cyclin D2 | 0.00589001 |
| WBP5 | WW domain binding protein 5 | 0.00588913 |
| TMSB15A | thymosin beta 15a | 0.00585722 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.00583802 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.00582734 |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.00579019 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00577236 |
| SEC61B | Sec61 beta subunit | 0.00576771 |
| PRTN3 | proteinase 3 | 0.00576412 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | 0.00574431 |
| RB1 | retinoblastoma 1 | 0.00573519 |
| DSP | desmoplakin | 0.00570797 |
| HMGN5 | high mobility group nucleosome binding domain 5 | 0.00568504 |
| BDH2 | 3-hydroxybutyrate dehydrogenase, type 2 | 0.00563325 |
| SNX13 | sorting nexin 13 | 0.00562823 |
| MMP8 | matrix metallopeptidase 8 | 0.00562321 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.00562296 |
| CTH | cystathionine gamma-lyase | 0.00560689 |
| HMG20B | high mobility group 20B | 0.005599 |
| GAL | galanin/GMAP prepropeptide | 0.00559065 |
| YME1L1 | YME1-like 1 ATPase | 0.00558846 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00558775 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | 0.00556443 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00556061 |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.00555478 |
| DDA1 | DET1 and DDB1 associated 1 | 0.00553338 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | 0.00547989 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | 0.00547743 |
| ZNF271P | zinc finger protein 271, pseudogene | 0.00547044 |
| RAD51AP1 | RAD51 associated protein 1 | 0.00546823 |
| MTF2 | metal response element binding transcription factor 2 | 0.00544619 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) | 0.00543918 |
| CENPU | centromere protein U | 0.00542353 |
| CIT | citron rho-interacting serine/threonine kinase | 0.0053927 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0053848 |
| SC5D | sterol-C5-desaturase | 0.00536882 |
| METAP2 | methionyl aminopeptidase 2 | 0.0053688 |
| CDCA4 | cell division cycle associated 4 | 0.0053673 |
| HMGB3 | high mobility group box 3 | 0.00534379 |
| CTSV | cathepsin V | 0.00534363 |
| PRR11 | proline rich 11 | 0.00533814 |
| PCLAF | PCNA clamp associated factor | 0.00532484 |
| TKTL1 | transketolase-like 1 | 0.00532309 |
| PRPF4 | pre-mRNA processing factor 4 | 0.00531106 |
| HRASLS | HRAS-like suppressor | 0.00529406 |
| NPTX1 | neuronal pentraxin I | 0.00527824 |
| EDRF1 | erythroid differentiation regulatory factor 1 | 0.00527813 |
| RNASE3 | ribonuclease, RNase A family, 3 | 0.00526399 |
| TLK2 | tousled-like kinase 2 | 0.00525971 |
| ZBED8 | zinc finger, BED-type containing 8 | 0.00525139 |
| PHGDH | phosphoglycerate dehydrogenase | 0.00524452 |
| TAC1 | tachykinin, precursor 1 | 0.00524285 |
| HLTF | helicase-like transcription factor | 0.0052419 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.00523848 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00522672 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00522621 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00522063 |
| KIF5B | kinesin family member 5B | 0.00521748 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.00518728 |
| HOXB2 | homeobox B2 | 0.00517733 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00516902 |
| C2CD5 | C2 calcium-dependent domain containing 5 | 0.00514806 |
| HOXC10 | homeobox C10 | 0.00514113 |
| ZNF721 | zinc finger protein 721 | 0.00513586 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | 0.00513223 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | 0.00512896 |
| ODR4 | odr-4 GPCR localization factor homolog | 0.00512664 |
| AMZ2 | archaelysin family metallopeptidase 2 | 0.00511997 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 | 0.00511542 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00511178 |
| SPATA7 | spermatogenesis associated 7 | 0.00510181 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein | 0.0051012 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.00509467 |
| PWP1 | PWP1 homolog (S. cerevisiae) | 0.00509128 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00508859 |
| ARG2 | arginase 2 | 0.00508629 |
| C10ORF88 | chromosome 10 open reading frame 88 | 0.00508279 |
| ZNF410 | zinc finger protein 410 | 0.00506967 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00504737 |
| COL4A6 | collagen, type IV, alpha 6 | 0.00504708 |
| ANXA3 | annexin A3 | 0.00503663 |
| WRN | Werner syndrome, RecQ helicase-like | 0.00503254 |
| WAC | WW domain containing adaptor with coiled-coil | 0.00503008 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00501373 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00501225 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00500798 |
| LOC283683 | uncharacterized LOC283683 | 0.00500206 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00498934 |
| CCNB2 | cyclin B2 | 0.00497535 |
| PLA2G12A | phospholipase A2, group XIIA | 0.00494926 |
| NTS | neurotensin | 0.00494693 |
| TESC | tescalcin | 0.00493886 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00492915 |
| ORC6 | origin recognition complex, subunit 6 | 0.00491211 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 0.00489061 |
| PRPF4B | pre-mRNA processing factor 4B | 0.00486996 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00486898 |
| BTG3 | BTG family, member 3 | 0.00486336 |
| RTN1 | reticulon 1 | 0.00482377 |
| ACE2 | angiotensin I converting enzyme 2 | 0.00481996 |
| MCOLN3 | mucolipin 3 | 0.00481798 |
| GYG1 | glycogenin 1 | 0.00480391 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 | 0.00479482 |
| STRAP | serine/threonine kinase receptor associated protein | 0.00476845 |
| MRPL42 | mitochondrial ribosomal protein L42 | 0.00476826 |
| CA11 | carbonic anhydrase XI | 0.00475846 |
| MXD4 | MAX dimerization protein 4 | 0.00475217 |
| CEP112 | centrosomal protein 112kDa | 0.00475207 |
| ATG4A | autophagy related 4A, cysteine peptidase | 0.00474366 |
| SH3BGR | SH3 domain binding glutamate-rich protein | 0.0047377 |
| CYBRD1 | cytochrome b reductase 1 | 0.00472848 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00472407 |
| TNIK | TRAF2 and NCK interacting kinase | 0.00472327 |
| ZNF160 | zinc finger protein 160 | 0.00471964 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 0.00471912 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00471838 |
| ZC3H14 | zinc finger CCCH-type containing 14 | 0.00471804 |
| RAD51C | RAD51 paralog C | 0.00470974 |
| SMC2 | structural maintenance of chromosomes 2 | 0.00470177 |
| ELP1 | elongator acetyltransferase complex subunit 1 | 0.00470124 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0046958 |
| DENND1B | DENN/MADD domain containing 1B | 0.00469538 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | 0.00468609 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00467725 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 | 0.00467621 |
| NKX2-1 | NK2 homeobox 1 | 0.00466859 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.00466488 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | 0.00466274 |
| MED21 | mediator complex subunit 21 | 0.00464512 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00461885 |
| RTN2 | reticulon 2 | 0.00461686 |
| DKK4 | dickkopf WNT signaling pathway inhibitor 4 | 0.00461038 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00460213 |
| GPI | glucose-6-phosphate isomerase | 0.00458997 |
| TMEM106C | transmembrane protein 106C | 0.00458993 |
| SHOX2 | short stature homeobox 2 | 0.00458889 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | 0.00457952 |
| CLGN | calmegin | 0.00457788 |
| FAM50B | family with sequence similarity 50, member B | 0.00457436 |
| CCNJ | cyclin J | 0.00457319 |
| GLRX2 | glutaredoxin 2 | 0.00456369 |
| MNS1 | meiosis-specific nuclear structural 1 | 0.00455857 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00455644 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.00455532 |
| ELOVL2 | ELOVL fatty acid elongase 2 | 0.00455007 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A | 0.00454838 |
| CHKB | choline kinase beta | 0.00454548 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.00454367 |
| CHGB | chromogranin B | 0.00454259 |
| ZNF84 | zinc finger protein 84 | 0.00453491 |
| ZNF711 | zinc finger protein 711 | 0.0045199 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 | 0.00451417 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00450665 |
| KRT5 | keratin 5, type II | 0.00450578 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.00450275 |
| MAGEB2 | melanoma antigen family B2 | 0.00450265 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.00449754 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00449714 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 | 0.00448398 |
| IGSF1 | immunoglobulin superfamily, member 1 | 0.00447815 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.00447328 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.00447125 |
| ZNF43 | zinc finger protein 43 | 0.00445765 |
| NGFR | nerve growth factor receptor | 0.00445624 |
| AKIRIN1 | akirin 1 | 0.00445086 |
| PAQR3 | progestin and adipoQ receptor family member III | 0.00444773 |
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT19 | keratin 19, type I | -0.0168184 |
| TNS3 | tensin 3 | -0.0164551 |
| TGM2 | transglutaminase 2 | -0.0144382 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0142377 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0128126 |
| S100A8 | S100 calcium binding protein A8 | -0.0123409 |
| CHRDL1 | chordin-like 1 | -0.0122943 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | -0.012243 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.0117906 |
| TRIB2 | tribbles pseudokinase 2 | -0.011629 |
| C1S | complement component 1, s subcomponent | -0.0114469 |
| TSPAN4 | tetraspanin 4 | -0.0111787 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0110933 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0109872 |
| TMEM100 | transmembrane protein 100 | -0.0108641 |
| PODXL | podocalyxin-like | -0.0108379 |
| SNAI2 | snail family zinc finger 2 | -0.0108084 |
| PMP22 | peripheral myelin protein 22 | -0.0107921 |
| GAS1 | growth arrest-specific 1 | -0.0105611 |
| C1R | complement component 1, r subcomponent | -0.0104987 |
| RBM47 | RNA binding motif protein 47 | -0.0104217 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.0103777 |
| CD200 | CD200 molecule | -0.0102775 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.0102647 |
| CES1 | carboxylesterase 1 | -0.0100972 |
| MMP7 | matrix metallopeptidase 7 | -0.0100653 |
| TRIM16 | tripartite motif containing 16 | -0.0100351 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.010018 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00998411 |
| NELL1 | NEL-like 1 (chicken) | -0.00992218 |
| AGR2 | anterior gradient 2 | -0.00988033 |
| S100A9 | S100 calcium binding protein A9 | -0.00985363 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0097966 |
| MX2 | MX dynamin-like GTPase 2 | -0.00967287 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00959413 |
| MLPH | melanophilin | -0.00957344 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.00952932 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00952714 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -0.00948449 |
| PALLD | palladin, cytoskeletal associated protein | -0.00946385 |
| LY75 | lymphocyte antigen 75 | -0.00931836 |
| INAVA | innate immunity activator | -0.00930542 |
| EMP1 | epithelial membrane protein 1 | -0.00926815 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00926055 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00918413 |
| HOPX | HOP homeobox | -0.00914185 |
| CD93 | CD93 molecule | -0.00907654 |
| IRS2 | insulin receptor substrate 2 | -0.00899261 |
| CRIP1 | cysteine-rich protein 1 (intestinal) | -0.00892958 |
| CA12 | carbonic anhydrase XII | -0.00890688 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00889623 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0088877 |
| PPL | periplakin | -0.00882604 |
| CCN2 | cellular communication network factor 2 | -0.00873538 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -0.00872515 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00872371 |
| MGLL | monoglyceride lipase | -0.00868987 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00861757 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.00861491 |
| ABLIM1 | actin binding LIM protein 1 | -0.00857551 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | -0.00854761 |
| RIN2 | Ras and Rab interactor 2 | -0.00853104 |
| CLIC5 | chloride intracellular channel 5 | -0.00852409 |
| AEBP1 | AE binding protein 1 | -0.00850865 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.00842053 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00838917 |
| ACKR3 | atypical chemokine receptor 3 | -0.00828986 |
| IL1RN | interleukin 1 receptor antagonist | -0.00825871 |
| ADGRG1 | adhesion G protein-coupled receptor G1 | -0.00822225 |
| SDC1 | syndecan 1 | -0.00813797 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00812641 |
| LAMB1 | laminin, beta 1 | -0.00812416 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00807159 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00804085 |
| CP | ceruloplasmin (ferroxidase) | -0.00801282 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00798802 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.00797512 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.00796498 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.00796316 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00795418 |
| KYNU | kynureninase | -0.00794783 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | -0.00793488 |
| SLC43A3 | solute carrier family 43, member 3 | -0.00792971 |
| MMP3 | matrix metallopeptidase 3 | -0.00792895 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.00784305 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.0078056 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00779679 |
| CRYAB | crystallin, alpha B | -0.00777428 |
| TRIM14 | tripartite motif containing 14 | -0.00775122 |
| FLNA | filamin A, alpha | -0.00772442 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.00769614 |
| XYLT1 | xylosyltransferase I | -0.00768957 |
| THBS2 | thrombospondin 2 | -0.00763455 |
| GALE | UDP-galactose-4-epimerase | -0.00762791 |
| COL11A1 | collagen, type XI, alpha 1 | -0.00761768 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00757476 |
| MYRF | myelin regulatory factor | -0.00756935 |
| HSPB8 | heat shock 22kDa protein 8 | -0.00756464 |
| CCNA2 | cyclin A2 | -0.00756106 |
| PRSS23 | protease, serine, 23 | -0.00755238 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00753175 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 | -0.00750986 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00747931 |
| GPX3 | glutathione peroxidase 3 | -0.00747091 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00745075 |
| SPON1 | spondin 1, extracellular matrix protein | -0.00744715 |
| NRCAM | neuronal cell adhesion molecule | -0.00744279 |
| MOXD1 | monooxygenase, DBH-like 1 | -0.00743902 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00743168 |
| OPN3 | opsin 3 | -0.00743151 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.00736883 |
| S100A4 | S100 calcium binding protein A4 | -0.00736485 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00733202 |
| EPHA2 | EPH receptor A2 | -0.00728912 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | -0.00728161 |
| LPIN1 | lipin 1 | -0.00726883 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | -0.00725339 |
| MFGE8 | milk fat globule-EGF factor 8 protein | -0.00720485 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0071956 |
| PSCA | prostate stem cell antigen | -0.00718888 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.00717983 |
| PLXNB2 | plexin B2 | -0.0071664 |
| AMOTL2 | angiomotin like 2 | -0.00716536 |
| GPX2 | glutathione peroxidase 2 | -0.00715829 |
| KRT13 | keratin 13, type I | -0.00711054 |
| THBD | thrombomodulin | -0.00706485 |
| KLK6 | kallikrein-related peptidase 6 | -0.00704788 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 | -0.00703052 |
| FSTL1 | follistatin-like 1 | -0.00702615 |
| PLN | phospholamban | -0.00700313 |
| TMPRSS2 | transmembrane protease, serine 2 | -0.00698222 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00697626 |
| MFAP5 | microfibrillar associated protein 5 | -0.00696888 |
| NEBL | nebulette | -0.00693692 |
| ANKRD28 | ankyrin repeat domain 28 | -0.00692523 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | -0.00691962 |
| AHR | aryl hydrocarbon receptor | -0.00685691 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | -0.00685259 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | -0.00684176 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | -0.0068321 |
| DUSP4 | dual specificity phosphatase 4 | -0.00681316 |
| NPAS2 | neuronal PAS domain protein 2 | -0.00680942 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -0.00680314 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.00679828 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00679333 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0067909 |
| CTSK | cathepsin K | -0.00677836 |
| GPX1 | glutathione peroxidase 1 | -0.00677729 |
| CLCA4 | chloride channel accessory 4 | -0.00676845 |
| PTK6 | protein tyrosine kinase 6 | -0.00674564 |
| PYCARD | PYD and CARD domain containing | -0.00674561 |
| FABP4 | fatty acid binding protein 4, adipocyte | -0.00673932 |
| SPP1 | secreted phosphoprotein 1 | -0.00672353 |
| MMP19 | matrix metallopeptidase 19 | -0.0067136 |
| RIPOR2 | RHO family interacting cell polarization regulator 2 | -0.00670032 |
| PER2 | period circadian clock 2 | -0.00669267 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00669156 |
| S100P | S100 calcium binding protein P | -0.00668769 |
| TNC | tenascin C | -0.00668682 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.00664297 |
| LDB2 | LIM domain binding 2 | -0.00659528 |
| LAMA5 | laminin, alpha 5 | -0.00658831 |
| MYOF | myoferlin | -0.00657489 |
| TRIM29 | tripartite motif containing 29 | -0.00656199 |
| COL10A1 | collagen, type X, alpha 1 | -0.00655767 |
| ACTN4 | actinin, alpha 4 | -0.00652723 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00652522 |
| LYST | lysosomal trafficking regulator | -0.00652123 |
| RAB20 | RAB20, member RAS oncogene family | -0.00649645 |
| ACTN1 | actinin, alpha 1 | -0.00649314 |
| DCN | decorin | -0.00648091 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.00646117 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00645838 |
| VWF | von Willebrand factor | -0.00645138 |
| CCNF | cyclin F | -0.00644464 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00643871 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.00643768 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.00643457 |
| SP110 | SP110 nuclear body protein | -0.00643279 |
| HMOX1 | heme oxygenase 1 | -0.00642897 |
| PGD | phosphogluconate dehydrogenase | -0.00642849 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | -0.00642618 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00641917 |
| CYRIA | CYFIP related Rac1 interactor A | -0.00641584 |
| MCF2L | MCF.2 cell line derived transforming sequence-like | -0.00640734 |
| RXRA | retinoid X receptor, alpha | -0.00640112 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00640081 |
| MUC16 | mucin 16, cell surface associated | -0.00639879 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.00638217 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0063771 |
| CFH | complement factor H | -0.00637165 |
| LOXL1 | lysyl oxidase-like 1 | -0.00636783 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00636161 |
| TBX2 | T-box 2 | -0.00635771 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00635405 |
| SERINC5 | serine incorporator 5 | -0.00634878 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00633919 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00633365 |
| MMP12 | matrix metallopeptidase 12 | -0.00632656 |
| ADCY7 | adenylate cyclase 7 | -0.00632063 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.00631035 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.00630875 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.00629543 |
| FBLN1 | fibulin 1 | -0.00629119 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -0.00627704 |
| GCHFR | GTP cyclohydrolase I feedback regulator | -0.00626421 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00626388 |
| SH3BP4 | SH3-domain binding protein 4 | -0.00625439 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 | -0.00625118 |
| MYLK | myosin light chain kinase | -0.00624252 |
| RBPMS | RNA binding protein with multiple splicing | -0.00623251 |
| KRT7 | keratin 7, type II | -0.00623038 |
| DUSP3 | dual specificity phosphatase 3 | -0.00622673 |
| PPAP2A | phosphatidic acid phosphatase type 2A | -0.00622038 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.0062202 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing | -0.00620848 |
| IL1R1 | interleukin 1 receptor, type I | -0.00620697 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.00619148 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00619092 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 | -0.00618459 |
| AQP3 | aquaporin 3 (Gill blood group) | -0.00618247 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0061738 |
| LMNB1 | lamin B1 | -0.00616133 |
| AOX1 | aldehyde oxidase 1 | -0.00615271 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.00614836 |
| METRN | meteorin, glial cell differentiation regulator | -0.00614746 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.00614446 |
| STC1 | stanniocalcin 1 | -0.00614415 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00613168 |
| PDHX | pyruvate dehydrogenase complex, component X | -0.00612799 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0061258 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | -0.00609978 |
| PNOC | prepronociceptin | -0.00609079 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.00608548 |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | -0.00608431 |
| MPZL2 | myelin protein zero-like 2 | -0.00607096 |
| TLCD3A | TLC domain containing 3A | -0.00606846 |
| VCAN | versican | -0.00606643 |
| LY96 | lymphocyte antigen 96 | -0.00604322 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.00603927 |
| ADCY9 | adenylate cyclase 9 | -0.00602656 |
| COL5A1 | collagen, type V, alpha 1 | -0.00602157 |
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | -0.00601047 |
| PLK2 | polo-like kinase 2 | -0.00600768 |
| LAMA4 | laminin, alpha 4 | -0.00599803 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00599451 |
| MMD | monocyte to macrophage differentiation-associated | -0.00597774 |
| CDCP1 | CUB domain containing protein 1 | -0.00597458 |
| ANXA9 | annexin A9 | -0.00596822 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | -0.00595433 |
