CREM Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description cAMP responsive element modulator|This gene encodes a bZIP transcription factor that binds to the cAMP responsive element found in many viral and cellular promoters. It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle, as well as other complex processes. Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness. Multiple alternatively spliced transcript variants encoding several different isoforms have been found for this gene, with some of them functioning as activators and some as repressors of transcription. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1390)
External Link http://www.ncbi.nlm.nih.gov/gene/1390
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Genes

36 interacting proteins for CREM from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ATF1 activating transcription factor 1
ATXN1 ataxin 1
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASP8AP2 caspase 8 associated protein 2
CD34 CD34 molecule
CDC34 cell division cycle 34
CDK1 cyclin-dependent kinase 1
CREB1 cAMP responsive element binding protein 1
CREB3L1 cAMP responsive element binding protein 3-like 1
CREB3L3 cAMP responsive element binding protein 3-like 3
CREB3L4 cAMP responsive element binding protein 3-like 4
CREBBP CREB binding protein
CSNK1A1 casein kinase 1, alpha 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2A2 casein kinase 2, alpha prime polypeptide
EMP3 epithelial membrane protein 3
FHL5 four and a half LIM domains 5
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
JUN jun proto-oncogene
KCNIP3 Kv channel interacting protein 3, calsenilin
MAPK3 mitogen-activated protein kinase 3
NFIL3 nuclear factor, interleukin 3 regulated
NRF1 nuclear respiratory factor 1
PIAS3 protein inhibitor of activated STAT, 3
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
SP100 SP100 nuclear antigen
SPI1 Spi-1 proto-oncogene
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TBP TATA box binding protein
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I