CRIPT Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description cysteine-rich PDZ-binding protein|This gene encodes a protein that binds to the PDZ3 peptide recognition domain. The encoded protein may modulates protein interactions with the cytoskeleton. A mutation in this gene resulted in short stature with microcephaly and distinctive facies. [provided by RefSeq, Jun 2014] (NCBI Entrez Gene Database, 9419)
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Genes

308 genes differentially expressed following the CRIPT gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SPATA45 spermatogenesis associated 45 2.5975
AK9 adenylate kinase 9 2.5975
DND1 DND microRNA-mediated repression inhibitor 1 2.5975
ECPAS Ecm29 proteasome adaptor and scaffold 2.5975
SDS serine dehydratase 2.5975
CARD6 caspase recruitment domain family, member 6 2.5975
ACADL acyl-CoA dehydrogenase, long chain 2.5975
PLA2G4B phospholipase A2, group IVB (cytosolic) 2.5975
KLK5 kallikrein-related peptidase 5 2.5975
SGMS2 sphingomyelin synthase 2 2.5975
RASAL3 RAS protein activator like 3 2.5975
PHOX2A paired-like homeobox 2a 2.5975
KCNIP3 Kv channel interacting protein 3, calsenilin 2.5975
ENTHD1 ENTH domain containing 1 2.5975
LMX1B LIM homeobox transcription factor 1, beta 2.5975
FIMP1 fertilization-influencing membrane protein 1 2.5975
TSKS testis-specific serine kinase substrate 2.5975
HRK harakiri, BCL2 interacting protein 2.5975
SHOX short stature homeobox 2.5975
PCDHB4 protocadherin beta 4 2.5975
LRRC8D leucine rich repeat containing 8 family, member D 2.59414
WDR87 WD repeat domain 87 2.59414
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 2.59414
PROKR1 prokineticin receptor 1 2.59414
CHADL chondroadherin-like 2.59414
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 2.59414
KLHL35 kelch-like family member 35 2.59414
COL19A1 collagen, type XIX, alpha 1 2.59414
TMPRSS11F transmembrane protease, serine 11F 2.59414
PRAMEF20 PRAME family member 20 2.59414
OVOL1 ovo-like zinc finger 1 2.59414
HRH4 histamine receptor H4 2.59414
HMGCLL1 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1 2.59414
RASL10A RAS-like, family 10, member A 2.59414
CEMP1 cementum protein 1 2.59414
SLC46A3 solute carrier family 46, member 3 2.59414
MSC musculin 2.59414
LRG1 leucine-rich alpha-2-glycoprotein 1 2.59414
SLC39A5 solute carrier family 39 (zinc transporter), member 5 2.59414
SLC9C2 solute carrier family 9, member C2 (putative) 2.59414
POSTN periostin, osteoblast specific factor 2.59414
CA9 carbonic anhydrase IX 2.59414
C9ORF152 chromosome 9 open reading frame 152 2.59414
KHDC3L KH domain containing 3-like, subcortical maternal complex member 2.59414
CEP295NL CEP295 N-terminal like 2.59414
PTX3 pentraxin 3, long 2.59414
PCDHB1 protocadherin beta 1 2.59414
DRICH1 aspartate-rich 1 2.59414
NOXO1 NADPH oxidase organizer 1 2.59414
DGAT2L6 diacylglycerol O-acyltransferase 2-like 6 2.59414
CCNB3 cyclin B3 2.59414
PEAR1 platelet endothelial aggregation receptor 1 2.59414
LMO1 LIM domain only 1 (rhombotin 1) 2.59414
GFAP glial fibrillary acidic protein 2.59414
DLX4 distal-less homeobox 4 2.59414
TBX20 T-box 20 2.59414
LOC124902694 uncharacterized LOC124902694 2.59414
STYXL2 serine/threonine/tyrosine interacting like 2 2.59414
STING1 stimulator of interferon response cGAMP interactor 1 2.59414
SELE selectin E 2.59414
PCDHGA9 protocadherin gamma subfamily A, 9 2.59414
ROPN1L rhophilin associated tail protein 1-like 2.59414
OPRM1 opioid receptor, mu 1 2.59414
ADGRG3 adhesion G protein-coupled receptor G3 2.59414
HTRA4 HtrA serine peptidase 4 2.59414
CPNE8-AS1 CPNE8 antisense RNA 1 2.59414
FYB1 FYN binding protein 1 2.59414
SMIM36 small integral membrane protein 36 2.59414
ACP4 acid phosphatase 4 2.59414
GSTT4 glutathione S-transferase theta 4 2.59414
DEFB131B defensin beta 131B 2.59414
CPLANE2 ciliogenesis and planar polarity effector complex subunit 2 2.59414
CIROP ciliated left-right organizer metallopeptidase 2.59414
CABCOCO1 ciliary associated calcium binding coiled-coil 1 2.59414
DYNC2I1 dynein 2 intermediate chain 1 2.59414
CCN6 cellular communication network factor 6 2.59414
TMEM271 transmembrane protein 271 2.59414
FMO2 flavin containing monooxygenase 2 (non-functional) 2.59414
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa 2.59414
C20ORF202 chromosome 20 open reading frame 202 2.59414
ADGRG1 adhesion G protein-coupled receptor G1 2.59414
IL6 interleukin 6 2.59414
MSX2 msh homeobox 2 2.59414
PTP4A1 protein tyrosine phosphatase type IVA, member 1 2.59414
CD79A CD79a molecule, immunoglobulin-associated alpha 2.59414
CD79B CD79b molecule, immunoglobulin-associated beta 2.59414
CCDC13 coiled-coil domain containing 13 2.59414
MBD5 methyl-CpG binding domain protein 5 2.59414
ACTL8 actin-like 8 2.59414
PDE1B phosphodiesterase 1B, calmodulin-dependent 2.59414
SH3TC1 SH3 domain and tetratricopeptide repeats 1 2.59414
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 2.59414
IMPG2 interphotoreceptor matrix proteoglycan 2 2.59414
PLEK2 pleckstrin 2 2.59414
SAMD11 sterile alpha motif domain containing 11 2.59414
TARM1 T cell-interacting, activating receptor on myeloid cells 1 2.59414
GTSF1 gametocyte specific factor 1 2.59414
BARX1 BARX homeobox 1 2.59414
CDKN2A cyclin-dependent kinase inhibitor 2A 2.59414
PCBP3 poly(rC) binding protein 3 2.59414
NKX3-1 NK3 homeobox 1 2.59414
PTK6 protein tyrosine kinase 6 2.59414
AQP9 aquaporin 9 2.59414
ISL2 ISL LIM homeobox 2 2.59414
LPAR5 lysophosphatidic acid receptor 5 2.59414
PRRX1 paired related homeobox 1 2.59414
NUTM2A NUT family member 2A 2.59414
POU3F3 POU class 3 homeobox 3 2.59414
PXT1 peroxisomal, testis specific 1 2.59414
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2.59414
PLA1A phospholipase A1 member A 2.59414
SST somatostatin 2.59414
CD8A CD8a molecule 2.59414
CD8B CD8b molecule 2.59414
TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like 2.59414
HLA-DOB major histocompatibility complex, class II, DO beta 2.59414
OR13A1 olfactory receptor, family 13, subfamily A, member 1 2.59414
CGB7 chorionic gonadotropin, beta polypeptide 7 2.59414
PLEKHS1 pleckstrin homology domain containing, family S member 1 2.59414
EFCAB8 EF-hand calcium binding domain 8 2.59414
DNAH12 dynein, axonemal, heavy chain 12 2.59414
CT55 cancer/testis antigen 55 2.59414
RAD21L1 RAD21-like 1 (S. pombe) 2.59414
GLOD5 glyoxalase domain containing 5 2.59414
LRRC46 leucine rich repeat containing 46 2.59414
LCN2 lipocalin 2 2.59414
MAP3K19 mitogen-activated protein kinase kinase kinase 19 2.59414
NIPAL4 NIPA-like domain containing 4 2.59414
ALAS2 5'-aminolevulinate synthase 2 2.59414
NEK6 NIMA-related kinase 6 2.59414
NPBWR1 neuropeptides B/W receptor 1 2.59414
LRRC32 leucine rich repeat containing 32 2.59414
DMRTC1 DMRT-like family C1 2.59414
SLCO2B1 solute carrier organic anion transporter family, member 2B1 2.59414
FBP2 fructose-1,6-bisphosphatase 2 2.59414
SPAG6 sperm associated antigen 6 2.59414
GPAT2 glycerol-3-phosphate acyltransferase 2, mitochondrial 2.59414
PRR29 proline rich 29 2.59414
SPACA5 sperm acrosome associated 5 2.59414
C2ORF78 chromosome 2 open reading frame 78 2.59414
LAMB3 laminin, beta 3 2.59414
FAM151A family with sequence similarity 151, member A 2.59414
NPM2 nucleophosmin/nucleoplasmin 2 2.59414
MPL MPL proto-oncogene, thrombopoietin receptor 2.59414
GOLGA8J golgin A8 family, member J 2.59414
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 2.59414
VAX1 ventral anterior homeobox 1 2.59414
KLHL10 kelch-like family member 10 2.59414
FGF9 fibroblast growth factor 9 2.59414
POU4F1 POU class 4 homeobox 1 2.59414
ITGB7 integrin, beta 7 2.59414
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 2.59414
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) 2.59414
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 2.59414
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 2.59414
CLEC9A C-type lectin domain family 9, member A 2.59414
PAIP1 poly(A) binding protein interacting protein 1 2.59414
IRX5 iroquois homeobox 5 2.59414
ANXA2R annexin A2 receptor 2.59414
BTBD19 BTB (POZ) domain containing 19 2.59414
GPR68 G protein-coupled receptor 68 2.59414
UBXN10 UBX domain protein 10 2.59414
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 2.56686
FZD7 frizzled class receptor 7 2.53404
NTN5 netrin 5 2.50471
PADI4 peptidyl arginine deiminase, type IV 2.50471
ITLN2 intelectin 2 2.49622
CDK10 cyclin-dependent kinase 10 2.46574
ZNF692 zinc finger protein 692 2.42485
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 2.41806
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 2.4083
GLRB glycine receptor, beta 2.38035
MT1X metallothionein 1X 2.35555
ITGA6 integrin, alpha 6 2.35555
AGGF1 angiogenic factor with G patch and FHA domains 1 2.3399
SLC45A1 solute carrier family 45, member 1 2.32681
CLCN1 chloride channel, voltage-sensitive 1 2.32681
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 2.32466
ZC3H3 zinc finger CCCH-type containing 3 2.30096
STK10 serine/threonine kinase 10 2.29544
YPEL1 yippee-like 1 (Drosophila) 2.28571
ARMH3 armadillo like helical domain containing 3 2.27095
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa 2.24465
KIF1B kinesin family member 1B 2.23554
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 2.19459
CNOT8 CCR4-NOT transcription complex, subunit 8 2.19273
LGALSL lectin, galactoside-binding-like 2.19273
TMTC1 transmembrane and tetratricopeptide repeat containing 1 2.19002
SASH1 SAM and SH3 domain containing 1 2.18305
SH3D19 SH3 domain containing 19 2.16669
AGMO alkylglycerol monooxygenase 2.15448
GLI3 GLI family zinc finger 3 2.14635
WNT5B wingless-type MMTV integration site family, member 5B 2.14635
ASB16 ankyrin repeat and SOCS box containing 16 2.13388
CD24 CD24 molecule 2.13035
TSPAN18 tetraspanin 18 2.13035
NUMA1 nuclear mitotic apparatus protein 1 2.11141
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) 2.10577
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1 2.10412
TTC21A tetratricopeptide repeat domain 21A 2.09905
ERBB2 erb-b2 receptor tyrosine kinase 2 2.08538
RDX radixin 2.07281
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 2.06578
NDE1 nudE neurodevelopment protein 1 2.06345
HNRNPA1L3 heterogeneous nuclear ribonucleoprotein A1 like 3 2.05294
EFL1 elongation factor like GTPase 1 2.05049
UBALD1 UBA-like domain containing 1 2.03919
C20ORF96 chromosome 20 open reading frame 96 2.03526
KSR2 kinase suppressor of ras 2 2.03111
SEZ6 seizure related 6 homolog (mouse) 2.02979
ZNF33A zinc finger protein 33A 2.0263
ACOXL acyl-CoA oxidase-like 2.01283
TDRKH tudor and KH domain containing 2.01283

decreased expression

Symbol Name Standardized Value
SMYD2 SET and MYND domain containing 2 -2.5975
ABITRAM actin binding transcription modulator -2.5975
MRPL12 mitochondrial ribosomal protein L12 -2.5975
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.5975
ZNF528 zinc finger protein 528 -2.5975
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -2.59414
NAMPT nicotinamide phosphoribosyltransferase -2.59414
THOC3 THO complex 3 -2.59414
ZNF583 zinc finger protein 583 -2.59414
SLC10A4 solute carrier family 10, member 4 -2.59414
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2 -2.59414
KISS1R KISS1 receptor -2.59414
CCDC149 coiled-coil domain containing 149 -2.59414
CRMP1 collapsin response mediator protein 1 -2.59414
GLIS2 GLIS family zinc finger 2 -2.59414
ARHGAP39 Rho GTPase activating protein 39 -2.59414
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) -2.59414
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -2.59414
SPDYE10 speedy/RINGO cell cycle regulator family member E10 -2.59414
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F -2.59414
LMOD1 leiomodin 1 (smooth muscle) -2.59414
WNT3 wingless-type MMTV integration site family, member 3 -2.59414
MCMDC2 minichromosome maintenance domain containing 2 -2.56995
ATP5F1D ATP synthase F1 subunit delta -2.55661
DOCK4 dedicator of cytokinesis 4 -2.46574
PLXDC1 plexin domain containing 1 -2.41806
RPL15 ribosomal protein L15 -2.41806
CD4 CD4 molecule -2.39362
SGCE sarcoglycan, epsilon -2.39183
USP18 ubiquitin specific peptidase 18 -2.35555
INSR insulin receptor -2.35466
TMEM191C transmembrane protein 191C -2.32466
HHLA1 HERV-H LTR-associating 1 -2.31608
ZNF506 zinc finger protein 506 -2.31408
IFT70B intraflagellar transport 70B -2.30102
PEAK3 PEAK family member 3 -2.30102
SPMIP11 sperm microtubule inner protein 11 -2.30102
REPS2 RALBP1 associated Eps domain containing 2 -2.30102
PCDHGB3 protocadherin gamma subfamily B, 3 -2.30102
CDNF cerebral dopamine neurotrophic factor -2.30102
PROZ protein Z, vitamin K-dependent plasma glycoprotein -2.30102
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -2.30102
FAM43B family with sequence similarity 43, member B -2.30102
OR2A12 olfactory receptor, family 2, subfamily A, member 12 -2.30102
POM121L2 POM121 transmembrane nucleoporin-like 2 -2.30102
CNTN5 contactin 5 -2.30102
TUBB1 tubulin, beta 1 class VI -2.30102
PDZRN4 PDZ domain containing ring finger 4 -2.30102
MIXL1 Mix paired-like homeobox -2.30102
C16ORF54 chromosome 16 open reading frame 54 -2.30102
WDR24 WD repeat domain 24 -2.30102
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 -2.30102
SAP25 Sin3A-associated protein, 25kDa -2.30102
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 -2.30102
SIDT1 SID1 transmembrane family, member 1 -2.30102
BCAS1 breast carcinoma amplified sequence 1 -2.30102
CBX8 chromobox homolog 8 -2.30102
TTC13 tetratricopeptide repeat domain 13 -2.30102
FOXP2 forkhead box P2 -2.30102
TTC29 tetratricopeptide repeat domain 29 -2.30102
STOML1 stomatin (EPB72)-like 1 -2.30102
PRPH2 peripherin 2 (retinal degeneration, slow) -2.30102
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) -2.30102
SEC14L1 SEC14-like 1 (S. cerevisiae) -2.27769
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -2.27508
ANKRD28 ankyrin repeat domain 28 -2.26517
CRIPT cysteine-rich PDZ-binding protein -2.25302
F8 coagulation factor VIII, procoagulant component -2.24621
LZTS3 leucine zipper, putative tumor suppressor family member 3 -2.23896
STK40 serine/threonine kinase 40 -2.22121
GOLPH3 golgi phosphoprotein 3 (coat-protein) -2.21009
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide -2.19371
ZNF823 zinc finger protein 823 -2.18984
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.18977
RHPN1 rhophilin, Rho GTPase binding protein 1 -2.18305
HAPLN1 hyaluronan and proteoglycan link protein 1 -2.18305
B4GALNT3 beta-1,4-N-acetyl-galactosaminyl transferase 3 -2.18305
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L -2.18264
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 -2.16637
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3 -2.15774
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 -2.15774
CC2D2B coiled-coil and C2 domain containing 2B -2.15774
CWF19L1 CWF19-like 1, cell cycle control (S. pombe) -2.15597
GHRL ghrelin/obestatin prepropeptide -2.14635
CSK c-src tyrosine kinase -2.13829
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 -2.11114
HAP1 huntingtin-associated protein 1 -2.10936
KATNAL1 katanin p60 subunit A-like 1 -2.10577
HLA-DMA major histocompatibility complex, class II, DM alpha -2.09894
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -2.07931
AVIL advillin -2.07281
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 -2.06578
MCM3 minichromosome maintenance complex component 3 -2.0554
ZNF701 zinc finger protein 701 -2.0554
SMC1A structural maintenance of chromosomes 1A -2.01583