CRKL Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description v-crk avian sarcoma virus CT10 oncogene homolog-like|This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009] (NCBI Entrez Gene Database, 1399)
External Link https://ncbi.nlm.nih.gov/gene/1399
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Genes

500 genes differentially expressed following the CRKL gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
LMO3 LIM domain only 3 (rhombotin-like 2) 0.0588153
POSTN periostin, osteoblast specific factor 0.0547303
SEPP1 selenoprotein P, plasma, 1 0.0545793
RGCC regulator of cell cycle 0.0533065
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.0513442
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.0508172
ZNF395 zinc finger protein 395 0.0488673
CFI complement factor I 0.0478068
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 0.0477349
TIMP3 TIMP metallopeptidase inhibitor 3 0.0470954
VEGFA vascular endothelial growth factor A 0.0441172
METTL7A methyltransferase like 7A 0.0434517
SH3BGRL SH3 domain binding glutamate-rich protein like 0.0407711
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.040699
APOD apolipoprotein D 0.0402891
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.0399303
MET MET proto-oncogene, receptor tyrosine kinase 0.0398463
PDGFD platelet derived growth factor D 0.03983
PLPP3 phospholipid phosphatase 3 0.0386802
HNMT histamine N-methyltransferase 0.0385153
SPINK1 serine peptidase inhibitor, Kazal type 1 0.0383951
LTBP1 latent transforming growth factor beta binding protein 1 0.0377583
INHBB inhibin, beta B 0.0373341
CLEC2B C-type lectin domain family 2, member B 0.0373072
ZNF277 zinc finger protein 277 0.0370355
SKAP2 src kinase associated phosphoprotein 2 0.0369398
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.0363848
PEG10 paternally expressed 10 0.0360708
SELENBP1 selenium binding protein 1 0.0360631
PLAT plasminogen activator, tissue 0.0359796
ANXA1 annexin A1 0.0358186
SLC16A4 solute carrier family 16, member 4 0.0355909
INAVA innate immunity activator 0.0354156
MPZL2 myelin protein zero-like 2 0.0352034
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0344648
CDC25B cell division cycle 25B 0.0342022
CPE carboxypeptidase E 0.0338813
ZFP36L1 ZFP36 ring finger protein-like 1 0.0333958
COL1A2 collagen, type I, alpha 2 0.0333015
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.0329496
GLUL glutamate-ammonia ligase 0.0326596
AGRN agrin 0.0326297
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.0325712
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.0325142
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.0324152
FOLR1 folate receptor 1 (adult) 0.0321658
NT5E 5'-nucleotidase, ecto (CD73) 0.031566
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.0314948
ZNF12 zinc finger protein 12 0.0314678
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.0314586
WSB1 WD repeat and SOCS box containing 1 0.0312977
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 0.0312438
SCPEP1 serine carboxypeptidase 1 0.0312129
TLR4 toll-like receptor 4 0.0311887
CD44 CD44 molecule (Indian blood group) 0.0310945
PSIP1 PC4 and SFRS1 interacting protein 1 0.0309875
ANXA4 annexin A4 0.0305851
CAST calpastatin 0.0305168
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.0304211
ORAI3 ORAI calcium release-activated calcium modulator 3 0.0303426
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.0302939
SLC38A1 solute carrier family 38, member 1 0.0300398
EAPP E2F-associated phosphoprotein 0.0299444
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0298591
FN1 fibronectin 1 0.0297147
CD58 CD58 molecule 0.0296897
PTN pleiotrophin 0.0296535
KRAS Kirsten rat sarcoma viral oncogene homolog 0.0296395
MMP1 matrix metallopeptidase 1 0.0296116
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.0295997
FCGBP Fc fragment of IgG binding protein 0.0294974
NEBL nebulette 0.029454
F13A1 coagulation factor XIII, A1 polypeptide 0.0294044
LPXN leupaxin 0.0293558
LPAR6 lysophosphatidic acid receptor 6 0.0292256
YPEL5 yippee-like 5 (Drosophila) 0.0290799
SALL2 spalt-like transcription factor 2 0.0289079
OSBPL10 oxysterol binding protein-like 10 0.0288616
HOXA5 homeobox A5 0.0288474
LY96 lymphocyte antigen 96 0.0287694
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0287085
GREM1 gremlin 1, DAN family BMP antagonist 0.0286423
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.0286269
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.02827
SDC2 syndecan 2 0.0282632
BTG1 B-cell translocation gene 1, anti-proliferative 0.0276514
ACOX2 acyl-CoA oxidase 2, branched chain 0.0276221
PLXNB2 plexin B2 0.0275318
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.0275122
CPA3 carboxypeptidase A3 (mast cell) 0.0274396
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.0274223
MECOM MDS1 and EVI1 complex locus 0.0272976
FLRT3 fibronectin leucine rich transmembrane protein 3 0.0272903
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 0.0271923
COL4A5 collagen, type IV, alpha 5 0.0271531
SSBP2 single-stranded DNA binding protein 2 0.02713
NMRK1 nicotinamide riboside kinase 1 0.0270867
IL7R interleukin 7 receptor 0.0270459
RGS16 regulator of G-protein signaling 16 0.0270233
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0269161
ACOT13 acyl-CoA thioesterase 13 0.0266741
AKR1C3 aldo-keto reductase family 1, member C3 0.0266314
LMBRD1 LMBR1 domain containing 1 0.0266208
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0265021
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.0264072
FAM198B family with sequence similarity 198, member B 0.0263462
CLC Charcot-Leyden crystal galectin 0.0263119
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.0262769
FLT1 fms-related tyrosine kinase 1 0.0262279
DPP4 dipeptidyl-peptidase 4 0.0261762
TLN1 talin 1 0.0259815
IER5 immediate early response 5 0.0259651
EGLN3 egl-9 family hypoxia-inducible factor 3 0.0258408
BHLHE41 basic helix-loop-helix family, member e41 0.0257377
LYPD1 LY6/PLAUR domain containing 1 0.0257019
SSPN sarcospan 0.0256501
TESK1 testis-specific kinase 1 0.0255897
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.0254655
IPO13 importin 13 0.0254643
CTSH cathepsin H 0.0253838
NARF nuclear prelamin A recognition factor 0.0253593
RNASE6 ribonuclease, RNase A family, k6 0.0251761
DIPK1A divergent protein kinase domain 1A 0.0251632
LEPROT leptin receptor overlapping transcript 0.0251439
CETN2 centrin, EF-hand protein, 2 0.0249753
PPP1R13B protein phosphatase 1, regulatory subunit 13B 0.0249509
CBX1 chromobox homolog 1 0.0245715
ADORA2B adenosine A2b receptor 0.0245646
DNALI1 dynein, axonemal, light intermediate chain 1 0.0244312
SOX2 SRY (sex determining region Y)-box 2 0.0244088
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.0243653
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.024365
PRNP prion protein 0.0243327
ADAM9 ADAM metallopeptidase domain 9 0.0243326
LDOC1 leucine zipper, down-regulated in cancer 1 0.0243147
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha 0.0243016
BPHL biphenyl hydrolase-like (serine hydrolase) 0.024287
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 0.0242478
STON1 stonin 1 0.0240992
CDC20 cell division cycle 20 0.0240634
NELL1 NEL-like 1 (chicken) 0.0240422
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.0240185
CP ceruloplasmin (ferroxidase) 0.0240018
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.0239857
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G 0.023925
ANPEP alanyl (membrane) aminopeptidase 0.0238659
CREB1 cAMP responsive element binding protein 1 0.0238409
OXA1L oxidase (cytochrome c) assembly 1-like 0.0237688
RNF19B ring finger protein 19B 0.0237415
BEX1 brain expressed, X-linked 1 0.0237411
CUTA cutA divalent cation tolerance homolog (E. coli) 0.0236894
PNRC1 proline-rich nuclear receptor coactivator 1 0.0236019
HOXB2 homeobox B2 0.0234715
SGCE sarcoglycan, epsilon 0.0234707
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.0234678
CXCL14 chemokine (C-X-C motif) ligand 14 0.0234358
EPS8 epidermal growth factor receptor pathway substrate 8 0.0234349
RGL2 ral guanine nucleotide dissociation stimulator-like 2 0.0233295
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.0232046
CXADR coxsackie virus and adenovirus receptor 0.0231664
SEC14L1 SEC14-like 1 (S. cerevisiae) 0.0231377
TTYH1 tweety family member 1 0.0231285
PCYOX1 prenylcysteine oxidase 1 0.0230142
CD86 CD86 molecule 0.0229771
CPQ carboxypeptidase Q 0.0229547
SNX13 sorting nexin 13 0.0229184
ZNF580 zinc finger protein 580 0.0228572
ASPH aspartate beta-hydroxylase 0.0228436
ALB albumin 0.0228378
HIST1H2AC histone cluster 1, H2ac 0.0228326
HBP1 HMG-box transcription factor 1 0.0227613
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 0.022758
AKAP1 A kinase (PRKA) anchor protein 1 0.0227518
A2M alpha-2-macroglobulin 0.0227389
TES testin LIM domain protein 0.0226562
NEU1 sialidase 1 (lysosomal sialidase) 0.0226486
SFTPA2 surfactant protein A2 0.0226186
GSTK1 glutathione S-transferase kappa 1 0.0225118
SCRG1 stimulator of chondrogenesis 1 0.0223936
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 0.0223402
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.0223279
AHR aryl hydrocarbon receptor 0.0223136
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 0.0222581
ADIRF adipogenesis regulatory factor 0.0221399
TOB1 transducer of ERBB2, 1 0.0221207
GIMAP6 GTPase, IMAP family member 6 0.0221098
DENND1B DENN/MADD domain containing 1B 0.0220876
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.022084
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.0220551
GNS glucosamine (N-acetyl)-6-sulfatase 0.0220548
OPHN1 oligophrenin 1 0.0220117
CD14 CD14 molecule 0.0219849
TMEM50B transmembrane protein 50B 0.0219755
ADGRF5 adhesion G protein-coupled receptor F5 0.0218049
COLEC12 collectin sub-family member 12 0.0218048
ZNF467 zinc finger protein 467 0.0217866
TMX4 thioredoxin-related transmembrane protein 4 0.0217848
AREG amphiregulin 0.0217724
PELI1 pellino E3 ubiquitin protein ligase 1 0.0217482
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 0.0217367
STC1 stanniocalcin 1 0.0216826
ATXN10 ataxin 10 0.021627
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.0215789
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.0215728
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.0215514
BEX4 brain expressed, X-linked 4 0.0215321
FAM107A family with sequence similarity 107, member A 0.021513
COL5A2 collagen, type V, alpha 2 0.0214899
AUTS2 autism susceptibility candidate 2 0.0214616
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.021433
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.0213947
CERT1 ceramide transporter 1 0.0213902
PTPRK protein tyrosine phosphatase, receptor type, K 0.0213822
CCNG2 cyclin G2 0.0213527
PHIP pleckstrin homology domain interacting protein 0.021324
SLC38A10 solute carrier family 38, member 10 0.0212754
MAOA monoamine oxidase A 0.0212219
PCP4 Purkinje cell protein 4 0.021093
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.0210499
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.0210375
EPAS1 endothelial PAS domain protein 1 0.0210228
GPC4 glypican 4 0.0209516
PON3 paraoxonase 3 0.0209423
ZNF652 zinc finger protein 652 0.0209292
TULP3 tubby like protein 3 0.0209202
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.0208877
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0208193
ENC1 ectodermal-neural cortex 1 (with BTB domain) 0.0208055
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.0207989
SERINC1 serine incorporator 1 0.0207519
MMP10 matrix metallopeptidase 10 0.0207158
EXOC5 exocyst complex component 5 0.0207083
AKR1C1 aldo-keto reductase family 1, member C1 0.0206989
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.0206834
HIST2H2BE histone cluster 2, H2be 0.0206406
PPT1 palmitoyl-protein thioesterase 1 0.0206401
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.0206315
CDK14 cyclin-dependent kinase 14 0.020576
VCAN versican 0.0204964
RIPOR2 RHO family interacting cell polarization regulator 2 0.0204884
GLIPR1 GLI pathogenesis-related 1 0.0204861
AMZ2 archaelysin family metallopeptidase 2 0.0204774
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0204615
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.0204563
DDIT3 DNA-damage-inducible transcript 3 0.0204503
NDUFA6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa 0.0203671
SNAP29 synaptosomal-associated protein, 29kDa 0.0203604
PBX1 pre-B-cell leukemia homeobox 1 0.0203185
SFTPB surfactant protein B 0.0202943
PNMA2 paraneoplastic Ma antigen 2 0.0202881

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -0.134637
COQ8A coenzyme Q8A -0.0777198
PROM1 prominin 1 -0.0540268
EIF5A eukaryotic translation initiation factor 5A -0.053899
CYBA cytochrome b-245, alpha polypeptide -0.0458811
TFF1 trefoil factor 1 -0.0443315
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.0436904
GOLM1 golgi membrane protein 1 -0.0424933
PRPF4 pre-mRNA processing factor 4 -0.0418629
EPB41L4B erythrocyte membrane protein band 4.1 like 4B -0.0406961
CXCL5 chemokine (C-X-C motif) ligand 5 -0.0401086
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.0396206
ACTA1 actin, alpha 1, skeletal muscle -0.0391445
SLN sarcolipin -0.0388569
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -0.037382
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.0367864
GAL galanin/GMAP prepropeptide -0.0363436
TNNC1 troponin C type 1 (slow) -0.0359849
JUNB jun B proto-oncogene -0.0359422
CKM creatine kinase, muscle -0.0357509
RAD23B RAD23 homolog B (S. cerevisiae) -0.0357289
MYBPC1 myosin binding protein C, slow type -0.0357019
DEFB1 defensin, beta 1 -0.0348451
CHEK2 checkpoint kinase 2 -0.0347009
HOXC6 homeobox C6 -0.0339535
SACS sacsin molecular chaperone -0.0339136
KLHL41 kelch-like family member 41 -0.0337315
TMSB15A thymosin beta 15a -0.0336611
C2CD2 C2 calcium-dependent domain containing 2 -0.0326218
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.0325364
HMOX1 heme oxygenase 1 -0.0323358
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.032262
GATA3 GATA binding protein 3 -0.0320632
FAM171A1 family with sequence similarity 171, member A1 -0.0320278
RHCG Rh family, C glycoprotein -0.0317811
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) -0.0316129
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide -0.0309456
CHI3L2 chitinase 3-like 2 -0.0309421
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0306997
TSPAN13 tetraspanin 13 -0.0306436
KIAA0125 KIAA0125 -0.0306226
PDLIM5 PDZ and LIM domain 5 -0.0304987
ENO3 enolase 3 (beta, muscle) -0.03036
UGCG UDP-glucose ceramide glucosyltransferase -0.0302318
GRWD1 glutamate-rich WD repeat containing 1 -0.0301422
G0S2 G0/G1 switch 2 -0.0299623
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.0299371
QDPR quinoid dihydropteridine reductase -0.0297283
LTF lactotransferrin -0.0295929
IL32 interleukin 32 -0.0293661
GRB14 growth factor receptor-bound protein 14 -0.0290937
TSPYL5 TSPY-like 5 -0.0289872
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.0289162
MYH2 myosin, heavy chain 2, skeletal muscle, adult -0.0288977
ESR1 estrogen receptor 1 -0.0288968
PTGES prostaglandin E synthase -0.0287435
SLC39A6 solute carrier family 39 (zinc transporter), member 6 -0.0286876
RASIP1 Ras interacting protein 1 -0.028616
MB myoglobin -0.0285119
MYB v-myb avian myeloblastosis viral oncogene homolog -0.0282391
MYOT myotilin -0.0282021
CCP110 centriolar coiled coil protein 110kDa -0.028184
ARID4A AT rich interactive domain 4A (RBP1-like) -0.0281464
PRMT1 protein arginine methyltransferase 1 -0.0279912
SORD sorbitol dehydrogenase -0.0279546
CTH cystathionine gamma-lyase -0.0279376
DLK1 delta-like 1 homolog (Drosophila) -0.0274164
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.0274052
NUTF2 nuclear transport factor 2 -0.0272864
H1-0 H1.0 linker histone -0.0269887
ACTC1 actin, alpha, cardiac muscle 1 -0.0269423
HNRNPL heterogeneous nuclear ribonucleoprotein L -0.0266366
KRT14 keratin 14, type I -0.0265143
C5ORF30 chromosome 5 open reading frame 30 -0.0264913
NAV3 neuron navigator 3 -0.026325
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.0262519
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) -0.0262175
SMCO4 single-pass membrane protein with coiled-coil domains 4 -0.0261592
CRISP3 cysteine-rich secretory protein 3 -0.0259392
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.0258455
TPM3 tropomyosin 3 -0.0257511
UBE2S ubiquitin-conjugating enzyme E2S -0.0254853
TNNC2 troponin C type 2 (fast) -0.0254317
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0254151
PSAT1 phosphoserine aminotransferase 1 -0.0253527
RETREG1 reticulophagy regulator 1 -0.0252676
KLK11 kallikrein-related peptidase 11 -0.0252652
MFAP3L microfibrillar-associated protein 3-like -0.0251719
LGALS13 lectin, galactoside-binding, soluble, 13 -0.0251656
KLHL21 kelch-like family member 21 -0.0250867
MYOZ2 myozenin 2 -0.0247196
FUS FUS RNA binding protein -0.0246281
CPS1 carbamoyl-phosphate synthase 1, mitochondrial -0.0244969
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.0244698
PFKL phosphofructokinase, liver -0.0243698
NKX3-1 NK3 homeobox 1 -0.0242764
TTN titin -0.0242484
COL6A2 collagen, type VI, alpha 2 -0.0242319
U2AF1 U2 small nuclear RNA auxiliary factor 1 -0.0241674
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.0240556
DES desmin -0.0239947
KLF2 Kruppel-like factor 2 -0.0238898
ERG v-ets avian erythroblastosis virus E26 oncogene homolog -0.0238802
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10 -0.023859
TBC1D4 TBC1 domain family, member 4 -0.0238338
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0237927
DNTT DNA nucleotidylexotransferase -0.0237086
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) -0.0236681
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) -0.0236642
ARPC5L actin related protein 2/3 complex, subunit 5-like -0.0234707
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.0234417
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.0233597
NPM3 nucleophosmin/nucleoplasmin 3 -0.0233385
IL1RN interleukin 1 receptor antagonist -0.0232054
ACTN2 actinin, alpha 2 -0.023204
ANXA6 annexin A6 -0.023154
NLRP2 NLR family, pyrin domain containing 2 -0.0231284
TFF3 trefoil factor 3 (intestinal) -0.0231046
ERLIN1 ER lipid raft associated 1 -0.0230881
MFAP4 microfibrillar-associated protein 4 -0.0230694
TACSTD2 tumor-associated calcium signal transducer 2 -0.0230656
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.0229897
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.0229599
RMI1 RecQ mediated genome instability 1 -0.0229571
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.0228743
MSX1 msh homeobox 1 -0.0228509
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 -0.0227847
CRCT1 cysteine-rich C-terminal 1 -0.0227551
ANO1 anoctamin 1, calcium activated chloride channel -0.0227248
CEP76 centrosomal protein 76kDa -0.0226872
BASP1 brain abundant, membrane attached signal protein 1 -0.0226495
KLK10 kallikrein-related peptidase 10 -0.0225786
TPD52L1 tumor protein D52-like 1 -0.0225419
TCAP titin-cap -0.0225315
GGCT gamma-glutamylcyclotransferase -0.0224684
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.0224609
UBE2M ubiquitin-conjugating enzyme E2M -0.0223711
TNNI2 troponin I type 2 (skeletal, fast) -0.0223292
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.0223091
CCL19 chemokine (C-C motif) ligand 19 -0.0222982
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 -0.0222767
DNA2 DNA replication helicase/nuclease 2 -0.0222734
SELL selectin L -0.0222724
PSD3 pleckstrin and Sec7 domain containing 3 -0.0222634
LMNB2 lamin B2 -0.0222617
PI3 peptidase inhibitor 3, skin-derived -0.0222505
TPM2 tropomyosin 2 (beta) -0.0221782
PRPF19 pre-mRNA processing factor 19 -0.0221743
TSPAN8 tetraspanin 8 -0.0220903
KRT16 keratin 16, type I -0.0220733
RCAN1 regulator of calcineurin 1 -0.022053
KBTBD11 kelch repeat and BTB (POZ) domain containing 11 -0.0220443
NUP58 nucleoporin 58 -0.0220304
TXNL4B thioredoxin-like 4B -0.0219716
TRIM16 tripartite motif containing 16 -0.0219652
C8ORF4 chromosome 8 open reading frame 4 -0.0217747
SEC16A SEC16 homolog A (S. cerevisiae) -0.0216819
RAD51 RAD51 recombinase -0.0216676
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 -0.0216555
AAGAB alpha- and gamma-adaptin binding protein -0.0216391
ARMCX6 armadillo repeat containing, X-linked 6 -0.0216246
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 -0.0215693
MYOM1 myomesin 1 -0.0214838
ABHD10 abhydrolase domain containing 10 -0.0214316
MARCO macrophage receptor with collagenous structure -0.021195
C9ORF91 chromosome 9 open reading frame 91 -0.0211925
IRS2 insulin receptor substrate 2 -0.021186
SFRP4 secreted frizzled-related protein 4 -0.0211852
CDC6 cell division cycle 6 -0.0211481
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.0211462
LTBP2 latent transforming growth factor beta binding protein 2 -0.0211181
NEFH neurofilament, heavy polypeptide -0.0211033
TUFT1 tuftelin 1 -0.0210784
GSTP1 glutathione S-transferase pi 1 -0.021035
PDE4DIP phosphodiesterase 4D interacting protein -0.0209461
SMPX small muscle protein, X-linked -0.0209458
SLC31A1 solute carrier family 31 (copper transporter), member 1 -0.0208002
GCA grancalcin, EF-hand calcium binding protein -0.0207816
DPT dermatopontin -0.0207107
SRPRB signal recognition particle receptor, B subunit -0.0207101
KIAA0100 KIAA0100 -0.0206967
FAM111A family with sequence similarity 111, member A -0.0206747
SOAT1 sterol O-acyltransferase 1 -0.0206484
PCNT pericentrin -0.0206312
HAMP hepcidin antimicrobial peptide -0.0206262
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 -0.0206171
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -0.0205989
MYOZ1 myozenin 1 -0.0205885
HSPB8 heat shock 22kDa protein 8 -0.0204727
AADAC arylacetamide deacetylase -0.0204601
WWC1 WW and C2 domain containing 1 -0.0204592
SPRR2B small proline-rich protein 2B -0.0204052
REEP1 receptor accessory protein 1 -0.020366
GYG1 glycogenin 1 -0.0203518
RBM14 RNA binding motif protein 14 -0.020331
PYCR1 pyrroline-5-carboxylate reductase 1 -0.0202148
STAC SH3 and cysteine rich domain -0.0201944
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -0.0201901
TRH thyrotropin-releasing hormone -0.0201696
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -0.0201071
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant -0.0200825
TARP TCR gamma alternate reading frame protein -0.0200736
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 -0.020073
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.0200217
PPP2R1B protein phosphatase 2, regulatory subunit A, beta -0.0199523
CEPT1 choline/ethanolamine phosphotransferase 1 -0.0199388
STK10 serine/threonine kinase 10 -0.019925
GREB1 growth regulation by estrogen in breast cancer 1 -0.019887
LOC283683 uncharacterized LOC283683 -0.0198841
RAB8A RAB8A, member RAS oncogene family -0.0198677
EXOSC4 exosome component 4 -0.0197802
ASPN asporin -0.0197522
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b -0.0197145
RBM26 RNA binding motif protein 26 -0.0196804
CBFB core-binding factor, beta subunit -0.0196501
PPIF peptidylprolyl isomerase F -0.0196304
SIK1 salt-inducible kinase 1 -0.019616
PDLIM3 PDZ and LIM domain 3 -0.0195983
CDH1 cadherin 1, type 1, E-cadherin (epithelial) -0.0195863
MED13L mediator complex subunit 13-like -0.0195781
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -0.0194847
RBM38 RNA binding motif protein 38 -0.0194658
AURKB aurora kinase B -0.0194633
CEP135 centrosomal protein 135kDa -0.0194514
SHCBP1 SHC SH2-domain binding protein 1 -0.0194421
ENTR1 endosome associated trafficking regulator 1 -0.0194291
PKP1 plakophilin 1 -0.0194067
MGAM maltase-glucoamylase -0.0193772
KRT34 keratin 34, type I -0.0193421
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase -0.0193351
LEPR leptin receptor -0.0193214
ENG endoglin -0.0192807
MAP7 microtubule-associated protein 7 -0.0192571
TMPO thymopoietin -0.0192317
JADE3 jade family PHD finger 3 -0.0192114
MMP9 matrix metallopeptidase 9 -0.0191999
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.0191926
MCM10 minichromosome maintenance complex component 10 -0.0191442
GLTP glycolipid transfer protein -0.0191301
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.0191228
EMILIN1 elastin microfibril interfacer 1 -0.0191199
MAGEB2 melanoma antigen family B2 -0.0191097
TYRP1 tyrosinase-related protein 1 -0.019062
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0190472
HBS1L HBS1-like translational GTPase -0.0190171
CTPS1 CTP synthase 1 -0.0189933
TNNI1 troponin I type 1 (skeletal, slow) -0.0189674
ORC6 origin recognition complex, subunit 6 -0.0189576
AFG3L2 AFG3-like AAA ATPase 2 -0.0189439
FLNB filamin B, beta -0.0189347