| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | C-reactive protein, pentraxin-related|The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 1401) |
| External Link | https://ncbi.nlm.nih.gov/gene/1401 |
| Similar Terms | |
| Downloads & Tools |
500 genes differentially expressed following the CRP gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFI27 | interferon, alpha-inducible protein 27 | 0.0195915 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0187658 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0153394 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0147614 |
| IFI44L | interferon-induced protein 44-like | 0.0145622 |
| S100A10 | S100 calcium binding protein A10 | 0.0145493 |
| MX1 | MX dynamin-like GTPase 1 | 0.0130353 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | 0.0115717 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.0115568 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.0111082 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0108175 |
| MSX1 | msh homeobox 1 | 0.0107191 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.0106693 |
| XAF1 | XIAP associated factor 1 | 0.0105867 |
| MX2 | MX dynamin-like GTPase 2 | 0.0103213 |
| FSTL1 | follistatin-like 1 | 0.0101174 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00996281 |
| HOPX | HOP homeobox | 0.00957849 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.00954417 |
| TXN | thioredoxin | 0.00921669 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | 0.00914286 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00897907 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00891324 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00883325 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00881012 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00877857 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00872185 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00870897 |
| PLS3 | plastin 3 | 0.00867871 |
| IFI44 | interferon-induced protein 44 | 0.0086112 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.00861063 |
| GLA | galactosidase, alpha | 0.00859246 |
| IRF7 | interferon regulatory factor 7 | 0.00851204 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00848832 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00848462 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.00847098 |
| P2RY14 | purinergic receptor P2Y, G-protein coupled, 14 | 0.00837824 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00833084 |
| PDLIM1 | PDZ and LIM domain 1 | 0.00830559 |
| DPP4 | dipeptidyl-peptidase 4 | 0.00825711 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.00824041 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.00821056 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00812248 |
| USP18 | ubiquitin specific peptidase 18 | 0.00797507 |
| NRCAM | neuronal cell adhesion molecule | 0.007954 |
| SPON2 | spondin 2, extracellular matrix protein | 0.00794321 |
| KRT14 | keratin 14, type I | 0.00789214 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00784899 |
| DSP | desmoplakin | 0.00783397 |
| MIR22HG | MIR22 host gene | 0.00779214 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00773102 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00772196 |
| TJP2 | tight junction protein 2 | 0.00771009 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00769419 |
| TARS1 | threonyl-tRNA synthetase 1 | 0.00758064 |
| EZR | ezrin | 0.00755237 |
| KRT18 | keratin 18, type I | 0.00750573 |
| MMP11 | matrix metallopeptidase 11 | 0.00750095 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0074939 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00748658 |
| SFTPB | surfactant protein B | 0.00746053 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.00745943 |
| DUSP5 | dual specificity phosphatase 5 | 0.00745599 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | 0.00743815 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | 0.00743178 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.00739131 |
| UPP1 | uridine phosphorylase 1 | 0.00730431 |
| PTCH1 | patched 1 | 0.0072793 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00726681 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.00724667 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00724291 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0072341 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00721056 |
| PFKP | phosphofructokinase, platelet | 0.00719848 |
| TRIM22 | tripartite motif containing 22 | 0.00718337 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.00716699 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00716503 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00715197 |
| TBX3 | T-box 3 | 0.0071192 |
| NOTCH2NL | notch 2 N-terminal like | 0.00703269 |
| CAPN3 | calpain 3, (p94) | 0.00702794 |
| RBM47 | RNA binding motif protein 47 | 0.00702485 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00700916 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.00700747 |
| SPRR2B | small proline-rich protein 2B | 0.00696518 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00693985 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00692586 |
| IFI35 | interferon-induced protein 35 | 0.00691964 |
| PODXL | podocalyxin-like | 0.00691816 |
| COL5A2 | collagen, type V, alpha 2 | 0.00689609 |
| AMDHD2 | amidohydrolase domain containing 2 | 0.00689019 |
| MYBPC1 | myosin binding protein C, slow type | 0.00686603 |
| BST2 | bone marrow stromal cell antigen 2 | 0.0068635 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00684789 |
| HSPB1 | heat shock 27kDa protein 1 | 0.00684174 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00682145 |
| BIN1 | bridging integrator 1 | 0.00680882 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00680514 |
| DIO2 | deiodinase, iodothyronine, type II | 0.00680112 |
| MYOF | myoferlin | 0.00677879 |
| RTN2 | reticulon 2 | 0.00677666 |
| CHMP5 | charged multivesicular body protein 5 | 0.00677508 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00674172 |
| APOD | apolipoprotein D | 0.00674044 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.00672397 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.00670567 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.00668618 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.00668447 |
| GAB2 | GRB2-associated binding protein 2 | 0.00664021 |
| SSX1 | synovial sarcoma, X breakpoint 1 | 0.00657445 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.00655752 |
| IRF9 | interferon regulatory factor 9 | 0.00655134 |
| REG1A | regenerating islet-derived 1 alpha | 0.00653907 |
| RHOA | ras homolog family member A | 0.00653641 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.00653565 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 0.00652854 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | 0.00651195 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.0065104 |
| REG3A | regenerating islet-derived 3 alpha | 0.00647645 |
| RIN2 | Ras and Rab interactor 2 | 0.00641671 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | 0.00639767 |
| GNLY | granulysin | 0.00639616 |
| FILIP1L | filamin A interacting protein 1-like | 0.00637797 |
| DUSP14 | dual specificity phosphatase 14 | 0.00635366 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | 0.00631431 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 0.0062757 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | 0.00623192 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.00622405 |
| EMP1 | epithelial membrane protein 1 | 0.00619939 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00619401 |
| CLDND1 | claudin domain containing 1 | 0.00618179 |
| GLRX | glutaredoxin (thioltransferase) | 0.00616183 |
| KCTD14 | potassium channel tetramerization domain containing 14 | 0.00615059 |
| BAG2 | BCL2-associated athanogene 2 | 0.00614528 |
| GPX2 | glutathione peroxidase 2 | 0.00614185 |
| SFN | stratifin | 0.00612659 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00611134 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00608605 |
| TDRD7 | tudor domain containing 7 | 0.00607134 |
| ADM | adrenomedullin | 0.00605529 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.00602626 |
| TBCA | tubulin folding cofactor A | 0.00601508 |
| HMBOX1 | homeobox containing 1 | 0.00600685 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.00600014 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00598792 |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 | 0.00598335 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.00597786 |
| SPP1 | secreted phosphoprotein 1 | 0.00595837 |
| PERP | PERP, TP53 apoptosis effector | 0.00593964 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.00593668 |
| MED13 | mediator complex subunit 13 | 0.00593353 |
| PELO | pelota homolog (Drosophila) | 0.0059208 |
| CCNG2 | cyclin G2 | 0.0059087 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0059001 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.00589679 |
| ANXA5 | annexin A5 | 0.00588567 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 0.00588093 |
| KLF13 | Kruppel-like factor 13 | 0.00587241 |
| CTH | cystathionine gamma-lyase | 0.00587124 |
| FAM189A2 | family with sequence similarity 189, member A2 | 0.00587047 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 0.00585734 |
| ZNF281 | zinc finger protein 281 | 0.00584264 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.00583674 |
| NCOA2 | nuclear receptor coactivator 2 | 0.0058357 |
| GOLGB1 | golgin B1 | 0.00582556 |
| ANXA2P2 | annexin A2 pseudogene 2 | 0.0058123 |
| CDK7 | cyclin-dependent kinase 7 | 0.0058014 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.00579639 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.00578695 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | 0.00575115 |
| POSTN | periostin, osteoblast specific factor | 0.00574371 |
| NKG7 | natural killer cell granule protein 7 | 0.00573211 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.00572477 |
| IGHMBP2 | immunoglobulin mu binding protein 2 | 0.00572449 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00572407 |
| CCNL2 | cyclin L2 | 0.0057093 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0057087 |
| PRF1 | perforin 1 (pore forming protein) | 0.0057065 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 0.00570428 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.00569287 |
| IGF2R | insulin-like growth factor 2 receptor | 0.00568528 |
| TSKU | tsukushi, small leucine rich proteoglycan | 0.00564232 |
| HBP1 | HMG-box transcription factor 1 | 0.00561395 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00558954 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.0055804 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.00557208 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.00555885 |
| SPAG9 | sperm associated antigen 9 | 0.00555581 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.00555351 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | 0.00553902 |
| CLDN15 | claudin 15 | 0.00553534 |
| LAMA2 | laminin, alpha 2 | 0.00553401 |
| HLA-B | major histocompatibility complex, class I, B | 0.00553365 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0055312 |
| UVRAG | UV radiation resistance associated | 0.0055193 |
| EGR1 | early growth response 1 | 0.00551915 |
| GSDMB | gasdermin B | 0.00551645 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.00551036 |
| JMJD1C | jumonji domain containing 1C | 0.00550114 |
| RBPMS | RNA binding protein with multiple splicing | 0.00549771 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0054903 |
| PHF11 | PHD finger protein 11 | 0.00547377 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.00547359 |
| CBX1 | chromobox homolog 1 | 0.00545189 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.00545131 |
| MT1E | metallothionein 1E | 0.00544603 |
| ACADVL | acyl-CoA dehydrogenase, very long chain | 0.00544286 |
| PMP22 | peripheral myelin protein 22 | 0.00544058 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.00544009 |
| RALB | v-ral simian leukemia viral oncogene homolog B | 0.00543914 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00543843 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00542718 |
| GPR88 | G protein-coupled receptor 88 | 0.00540197 |
| CTSL | cathepsin L | 0.00539883 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.00539816 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00538683 |
| NPC1 | Niemann-Pick disease, type C1 | 0.00538289 |
| VEGFA | vascular endothelial growth factor A | 0.00535847 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 | 0.00534414 |
| NAV2 | neuron navigator 2 | 0.00533815 |
| AMOTL2 | angiomotin like 2 | 0.00532701 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.00532567 |
| KLF6 | Kruppel-like factor 6 | 0.00531744 |
| KRT1 | keratin 1, type II | 0.00530892 |
| PNN | pinin, desmosome associated protein | 0.00530582 |
| B2M | beta-2-microglobulin | 0.00530503 |
| ITGA6 | integrin, alpha 6 | 0.00530244 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00529927 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.00529168 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 | 0.00528822 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00528614 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00528456 |
| ATP6V1E1 | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 | 0.00527454 |
| REXO2 | RNA exonuclease 2 | 0.00524059 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00523532 |
| IL32 | interleukin 32 | 0.00522053 |
| ITGA7 | integrin, alpha 7 | 0.00520815 |
| SETD5 | SET domain containing 5 | 0.00520185 |
| HOXB7 | homeobox B7 | 0.00520005 |
| TPD52 | tumor protein D52 | 0.00519796 |
| FADS3 | fatty acid desaturase 3 | 0.00519588 |
| KRT17 | keratin 17, type I | 0.00519229 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.00518857 |
| ANXA2 | annexin A2 | 0.00518428 |
| TMPRSS11E | transmembrane protease, serine 11E | 0.00518199 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.00518117 |
| MCM2 | minichromosome maintenance complex component 2 | 0.0051697 |
| TGM1 | transglutaminase 1 | 0.00516486 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00516357 |
| PRSS23 | protease, serine, 23 | 0.00515862 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0255645 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.0147389 |
| MMP9 | matrix metallopeptidase 9 | -0.0138413 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.0131515 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | -0.0125035 |
| NPTX2 | neuronal pentraxin II | -0.0118102 |
| WDR7 | WD repeat domain 7 | -0.0114991 |
| CLC | Charcot-Leyden crystal galectin | -0.0111243 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.0104883 |
| CDCA4 | cell division cycle associated 4 | -0.0104666 |
| TSPYL5 | TSPY-like 5 | -0.0104231 |
| COG7 | component of oligomeric golgi complex 7 | -0.0103325 |
| S100A8 | S100 calcium binding protein A8 | -0.0102051 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.0100881 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0100873 |
| PADI2 | peptidyl arginine deiminase, type II | -0.00993499 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.00971018 |
| PNMA8A | PNMA family member 8A | -0.00962366 |
| RXYLT1 | ribitol xylosyltransferase 1 | -0.00947773 |
| LYZ | lysozyme | -0.00940222 |
| IL7R | interleukin 7 receptor | -0.00931361 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | -0.00906242 |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | -0.00900651 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00889275 |
| MEF2C | myocyte enhancer factor 2C | -0.00881142 |
| C7 | complement component 7 | -0.00870292 |
| CSTA | cystatin A (stefin A) | -0.00869039 |
| LTF | lactotransferrin | -0.00859227 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.00858767 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -0.00855701 |
| GAS1 | growth arrest-specific 1 | -0.0084985 |
| IRX5 | iroquois homeobox 5 | -0.00832767 |
| BPI | bactericidal/permeability-increasing protein | -0.00819294 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -0.00807933 |
| ELANE | elastase, neutrophil expressed | -0.00807307 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00801199 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | -0.00799767 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00793502 |
| PBX1 | pre-B-cell leukemia homeobox 1 | -0.0079148 |
| IFRD2 | interferon-related developmental regulator 2 | -0.00786137 |
| MLF1 | myeloid leukemia factor 1 | -0.00781697 |
| EREG | epiregulin | -0.00780798 |
| CAMP | cathelicidin antimicrobial peptide | -0.00779501 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00779404 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | -0.00769272 |
| MSMO1 | methylsterol monooxygenase 1 | -0.00756884 |
| CD52 | CD52 molecule | -0.00753594 |
| THBS1 | thrombospondin 1 | -0.00746113 |
| A2M | alpha-2-macroglobulin | -0.00742633 |
| COPS7A | COP9 signalosome subunit 7A | -0.00739148 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | -0.00734501 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00730331 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | -0.00723474 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.00716876 |
| MPO | myeloperoxidase | -0.00713812 |
| CLGN | calmegin | -0.00711369 |
| CLDN10 | claudin 10 | -0.00709941 |
| S100P | S100 calcium binding protein P | -0.00709749 |
| NELL2 | NEL-like 2 (chicken) | -0.00705324 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00704092 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.00702713 |
| RPA2 | replication protein A2, 32kDa | -0.00700512 |
| STEAP3 | STEAP family member 3, metalloreductase | -0.00699837 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00699827 |
| FGFR3 | fibroblast growth factor receptor 3 | -0.00698156 |
| TGFA | transforming growth factor, alpha | -0.00695276 |
| BIRC5 | baculoviral IAP repeat containing 5 | -0.00692903 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00680116 |
| CPE | carboxypeptidase E | -0.00678154 |
| NPY1R | neuropeptide Y receptor Y1 | -0.0066479 |
| MMP8 | matrix metallopeptidase 8 | -0.0066429 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00661284 |
| SOX11 | SRY (sex determining region Y)-box 11 | -0.00656982 |
| ADD3 | adducin 3 (gamma) | -0.00650367 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00649128 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | -0.00645495 |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits | -0.00645435 |
| LAMP3 | lysosomal-associated membrane protein 3 | -0.00643652 |
| EHF | ets homologous factor | -0.00641701 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00634099 |
| S100A9 | S100 calcium binding protein A9 | -0.00633035 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -0.00631187 |
| STMN2 | stathmin 2 | -0.00630677 |
| BEX1 | brain expressed, X-linked 1 | -0.00628827 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00626419 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00624708 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00623089 |
| AUTS2 | autism susceptibility candidate 2 | -0.0062214 |
| CCNA1 | cyclin A1 | -0.00617942 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00617588 |
| CDK14 | cyclin-dependent kinase 14 | -0.00617507 |
| C5AR1 | complement component 5a receptor 1 | -0.00616604 |
| IMPACT | impact RWD domain protein | -0.00614581 |
| FOXM1 | forkhead box M1 | -0.00613652 |
| GCA | grancalcin, EF-hand calcium binding protein | -0.00611796 |
| GFRA1 | GDNF family receptor alpha 1 | -0.00609905 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.00607356 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00606832 |
| DCLK1 | doublecortin-like kinase 1 | -0.00606692 |
| ZBED8 | zinc finger, BED-type containing 8 | -0.00606292 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -0.00602097 |
| MNDA | myeloid cell nuclear differentiation antigen | -0.00601012 |
| NEBL | nebulette | -0.00600602 |
| TMEM47 | transmembrane protein 47 | -0.00600032 |
| AGBL5 | ATP/GTP binding protein-like 5 | -0.00597347 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.00596437 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | -0.00596299 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | -0.00596064 |
| ZNF274 | zinc finger protein 274 | -0.00595843 |
| CCNE2 | cyclin E2 | -0.00593666 |
| IFT74 | intraflagellar transport 74 | -0.00591876 |
| GPR183 | G protein-coupled receptor 183 | -0.00591854 |
| NLGN4X | neuroligin 4, X-linked | -0.00590725 |
| FABP7 | fatty acid binding protein 7, brain | -0.0059025 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0058777 |
| HBB | hemoglobin, beta | -0.00584832 |
| VANGL1 | VANGL planar cell polarity protein 1 | -0.0058388 |
| PRKD3 | protein kinase D3 | -0.00583475 |
| PROM1 | prominin 1 | -0.0058214 |
| HTRA1 | HtrA serine peptidase 1 | -0.00582004 |
| C5ORF30 | chromosome 5 open reading frame 30 | -0.005808 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.00580638 |
| NVL | nuclear VCP-like | -0.00580459 |
| TRMT5 | tRNA methyltransferase 5 | -0.00578383 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor | -0.00578269 |
| HHEX | hematopoietically expressed homeobox | -0.00577353 |
| TP53 | tumor protein p53 | -0.00577063 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00575297 |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | -0.00575251 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00575059 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00574677 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00574197 |
| LY75 | lymphocyte antigen 75 | -0.00573866 |
| AOX1 | aldehyde oxidase 1 | -0.00572536 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | -0.00571141 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.0057079 |
| H1-0 | H1.0 linker histone | -0.00570501 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.00569717 |
| SELL | selectin L | -0.00569663 |
| MAP7 | microtubule-associated protein 7 | -0.00568694 |
| TTC27 | tetratricopeptide repeat domain 27 | -0.00568422 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | -0.00565666 |
| RRM2 | ribonucleotide reductase M2 | -0.00565587 |
| CYBB | cytochrome b-245, beta polypeptide | -0.00564307 |
| DHCR7 | 7-dehydrocholesterol reductase | -0.00562609 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | -0.0056206 |
| TLR5 | toll-like receptor 5 | -0.0056051 |
| RTN1 | reticulon 1 | -0.00558779 |
| SLC35E3 | solute carrier family 35, member E3 | -0.00558412 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00556356 |
| CLU | clusterin | -0.00555985 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00553334 |
| LBR | lamin B receptor | -0.00553115 |
| ZNF331 | zinc finger protein 331 | -0.00552635 |
| ERLIN2 | ER lipid raft associated 2 | -0.00551967 |
| AZU1 | azurocidin 1 | -0.00550191 |
| TUBA1A | tubulin, alpha 1a | -0.00548606 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00547796 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00545815 |
| PLPBP | pyridoxal phosphate binding protein | -0.00545464 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 | -0.00544601 |
| C12ORF29 | chromosome 12 open reading frame 29 | -0.00543584 |
| SV2A | synaptic vesicle glycoprotein 2A | -0.00542998 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | -0.00542918 |
| SUSD4 | sushi domain containing 4 | -0.00542075 |
| MYL9 | myosin, light chain 9, regulatory | -0.00541633 |
| KIF15 | kinesin family member 15 | -0.00540852 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00540806 |
| CDCA3 | cell division cycle associated 3 | -0.00539815 |
| FAM13A | family with sequence similarity 13, member A | -0.0053905 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00535025 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | -0.00534519 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00534118 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.00532987 |
| ATXN7L3B | ataxin 7-like 3B | -0.00532728 |
| CBX5 | chromobox homolog 5 | -0.00532119 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00531994 |
| TMEM246 | transmembrane protein 246 | -0.00531701 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | -0.00531365 |
| H1-10 | H1.10 linker histone | -0.00529898 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | -0.00529111 |
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | -0.00528482 |
| CAND1 | cullin-associated and neddylation-dissociated 1 | -0.00526934 |
| AZIN1 | antizyme inhibitor 1 | -0.00526364 |
| BEX4 | brain expressed, X-linked 4 | -0.00525526 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit | -0.00524687 |
| HIRIP3 | HIRA interacting protein 3 | -0.00524488 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00524478 |
| PRTN3 | proteinase 3 | -0.00524069 |
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | -0.00523387 |
| ITGA8 | integrin, alpha 8 | -0.00522858 |
| LTA4H | leukotriene A4 hydrolase | -0.00522019 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | -0.00521575 |
| NBEA | neurobeachin | -0.0051879 |
| SELENBP1 | selenium binding protein 1 | -0.00517325 |
| HRASLS | HRAS-like suppressor | -0.00517068 |
| DIPK1A | divergent protein kinase domain 1A | -0.00516905 |
| UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) | -0.00516837 |
| PDE8B | phosphodiesterase 8B | -0.00514646 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | -0.00513237 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) | -0.0051234 |
| PF4 | platelet factor 4 | -0.00511548 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | -0.00510947 |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 | -0.00510534 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.00510154 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.0051002 |
| RPIA | ribose 5-phosphate isomerase A | -0.00509539 |
| TRIP13 | thyroid hormone receptor interactor 13 | -0.00508132 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00508101 |
| RNF144A | ring finger protein 144A | -0.00507196 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -0.00507047 |
| CHIT1 | chitinase 1 (chitotriosidase) | -0.00506638 |
| ISYNA1 | inositol-3-phosphate synthase 1 | -0.00506583 |
| PTDSS1 | phosphatidylserine synthase 1 | -0.00505731 |
| CRABP1 | cellular retinoic acid binding protein 1 | -0.00503394 |
| THEMIS2 | thymocyte selection associated family member 2 | -0.00503316 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00503252 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | -0.00502886 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.00502539 |
| SCG5 | secretogranin V | -0.00502342 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00501582 |
| CTSK | cathepsin K | -0.00501368 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00501077 |
| DCK | deoxycytidine kinase | -0.00500366 |
| LDB2 | LIM domain binding 2 | -0.00499614 |
| GAL | galanin/GMAP prepropeptide | -0.00498513 |
| CIRBP | cold inducible RNA binding protein | -0.00498391 |
| GPC4 | glypican 4 | -0.00497736 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00497718 |
| MSLN | mesothelin | -0.00497148 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.0049678 |
| NEK2 | NIMA-related kinase 2 | -0.00496639 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | -0.00496033 |
| CCNF | cyclin F | -0.00495622 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00495599 |
| MAP9 | microtubule-associated protein 9 | -0.0049414 |
| CRYM | crystallin, mu | -0.00494136 |
| LINC00623 | long intergenic non-protein coding RNA 623 | -0.00494002 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.00493534 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -0.0049342 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | -0.00492971 |
| BAMBI | BMP and activin membrane-bound inhibitor | -0.0049267 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00491962 |
| OLFM1 | olfactomedin 1 | -0.0049186 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00489152 |
| CTBP1 | C-terminal binding protein 1 | -0.00487784 |
| USP1 | ubiquitin specific peptidase 1 | -0.00487751 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.00487709 |
| GCHFR | GTP cyclohydrolase I feedback regulator | -0.00487561 |
| PITX1 | paired-like homeodomain 1 | -0.00486701 |
